Reposted by Yue Hao 郝樾Daniel Bolnick @danielbolnick.bsky.social · 10/06/2026I've been keeping this quiet for a while, but now's as good a time as any to announce: I have a book contract for a new textbook, Applied Evolutionary Medicine, with Princeton Univ Press. Core theme: "What, if anything, do medical practitioners do differently when they understand evolution"? 16810
Reposted by Yue Hao 郝樾Creight Photo 🌱☮️ @afewfromtheforest.bsky.social · 04/06/2026(earth forests) #ThankfulThursday 📍Pennsylvania 949771
Reposted by Yue Hao 郝樾Gavin Conant @gavin-conant.bsky.social · 01/06/2026Just posted a new pre-print on how buffering of cellular noise by changes in ploidy could be responsible for for hybrid vigor. I would be very interested in whether people find this a plausible idea or just "noise!" bioRxiv 2026.05.27.728238; doi: doi.org/10.64898/202...doi.org 011
Reposted by Yue Hao 郝樾Gavin Conant @gavin-conant.bsky.social · 18/05/2026With the addition of a new 8-genome dataset for the grass Rho polyploidy, POInT Browse is now up to 13 polyploidies, 87 genomes and almost 1 million genes. Check it out: wgd.statgen.ncsu.edu 031
Yue Hao 郝樾 @yuehao.bsky.social · 06/05/2026Androgen loss accelerates brain tumour growth via HPA axis activation www.nature.com/articles/s41... 000
Reposted by Yue Hao 郝樾Nucleic Acids Research @narjournal.bsky.social · 29/04/2026⭐ #NARBreakthrough ⭐ New study delivers the first chromosome-level phased assemblies, uncovering >50,000 #structuralvariants and rescuing millions of #unmappable reads in BJ and IMR-90 human cell lines. 📖 Read here: doi.org/10.1093/nar/... #Genomics #CellLines #CommunityResource 143
Yue Hao 郝樾 @yuehao.bsky.social · 01/04/2026Gapless pangenome analyses reveal fast Brassica rapa subspeciation | Science www.science.org/doi/10.1126/...science.orgGapless pangenome analyses reveal fast Brassica rapa subspeciationBrassica rapa (Br) encompasses many morphotypes and subspecies, so it is a good model with which to investigate plant diversification and subspeciation. Here, we resequenced the genomes of 1720 Br acc... 031
Reposted by Yue Hao 郝樾Christian Landry @christianlandry.bsky.social · 23/03/2026For those interested, the papers associated with my talk: pubmed.ncbi.nlm.nih.gov/39146405/ pubmed.ncbi.nlm.nih.gov/41699381/ pubmed.ncbi.nlm.nih.gov/36735790/ pubmed.ncbi.nlm.nih.gov/36050399/ pubmed.ncbi.nlm.nih.gov/41763210/ pubmed.ncbi.nlm.nih.gov/31454312/pubmed.ncbi.nlm.nih.govCompensatory mutations potentiate constructive neutral evolution by gene duplication - PubMedThe functions of proteins generally depend on their assembly into complexes. During evolution, some complexes have transitioned from homomers encoded by a single gene to heteromers encoded by duplicate genes. This transition could occur without adaptive evolution through intermolecular compensatory … 0209
Reposted by Yue Hao 郝樾Graham Coop @gcbias.bsky.social · 12/03/2026A fitting end to teaching speciation in the last week of undergrad evolution. Darwin 1858 March 11th, definitely was running on empty in week 10 of the quarter. 05112
Reposted by Yue Hao 郝樾Wouter De Coster @wdecoster.bsky.social · 12/03/2026Thrilled to see our work from the past years finally published! We found a novel repeat expansion in the GOLGA8A gene in 60% of the aFTLD-U patients, a rare subtype of frontotemporal dementia. Huge thanks to all collaborators and patients for making this possible. www.nature.com/articles/s41...nature.comA repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions - Nature GeneticsGenome-wide analysis coupled with long-read sequencing identifies a repeat expansion in GOLGA8A associated with high risk for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusi... 032
Reposted by Yue Hao 郝樾Nature @nature.com · 10/03/2026For the first time, researchers have simulated nearly every chemical reaction in a living bacterial cell go.nature.com/4lrAulMgo.nature.com'Virtual cell' captures most-basic process of life: bacterial divisionResearchers simulated nearly every molecule in a bacterial cell — and then watched the cell grow and reproduce. 07929
Reposted by Yue Hao 郝樾Wolfram Höps @wolfram-hops.bsky.social · 06/03/2026🔄 Inversions predispose to recurrent deletions and duplications in chromsome 15q13.3. 🔁 Using de-novo assemblies of 10 patient-parent trios, we investigated how recurrent copy-number variants (CNVs) in the 15q13.3 locus arise. www.biorxiv.org/content/10.6... A brief tour (1/17) 1104
Reposted by Yue Hao 郝樾Gavin Conant @gavin-conant.bsky.social · 18/12/2025Returning the page proofs for my quantitative biology textbook, out in February: www.routledge.com/Quantitative...routledge.comQuantitative Biology: Life from the NumbersBiology at all scales has become a data-driven science, with large-scale datasets driving fields from population genomics to ecology. Practicing biologists have no choice but to use computational appr... 0143
Reposted by Yue Hao 郝樾Gavin Conant @gavin-conant.bsky.social · 31/10/2025Congratulations to Lindsey Zanno of NC State and her collaborator for showing that what was thought to be a juvenile T. rex is actually a new species! www.nature.com/articles/d41...nature.com‘Teenage T. rex’ fossil is actually a different speciesThe discovery of smaller predator Nanotyrannus could prompt a re-think of tyrannosaur evolution. 021
Reposted by Yue Hao 郝樾MILO Lab @milolab.bsky.social · 19/11/2025If you are at #SNO2025 be sure to check @milolab.bsky.social talks and posters including a keynote talk by @heilandhenrik.bsky.social #Hawaii🏖️🌊 #glioblastoma 051
Reposted by Yue Hao 郝樾J. Chris Pires @jchrispires.bsky.social · 03/08/2025Traveled to Columbia, Missouri, to celebrate the successful #PhD defenses of my last two esteemed graduate students at the University of Missouri-Columbia! Michael Pisias (PhD Plant Biology, advised by Bing Yang); & Shawn K. Thomas (PhD Biology, co-advised by Jacob Washburn). #Crop #Evolution #agsky 2028124
Reposted by Yue Hao 郝樾Society for Molecular Biology and Evolution @official-smbe.bsky.social · 21/07/2025 011
Reposted by Yue Hao 郝樾Society for Molecular Biology and Evolution @official-smbe.bsky.social · 18/06/2025#SMBE2025 Symposium 4: Gene trees and beyond: genealogical methods and their applications in evolutionary genetics 🔗 smbe2025.scimeeting.cn/en/web/program/25070 152
Reposted by Yue Hao 郝樾ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 22/04/2025to really take your research to the next level, it is important to build interdisciplinary teams #collaboration #scientificinterfaces 0457
Reposted by Yue Hao 郝樾Tressie McMillan Cottom @tressiemcphd.bsky.social · 21/04/2025The L.A. Times names THICK one of the best non-fiction books of the last 30 years. I will be honest with you, even I cannot always believe that this is my life. Thank you. Very much. www.latimes.com/entertainmen...latimes.comThe 30 best nonfiction books of the last 30 yearsTo celebrate the 30th edition of the L.A. Times Festival of Books, we asked authors, editors, critics and scholars to select the 30 best nonfiction books since the festival was inaugurated. 453644326
Reposted by Yue Hao 郝樾Prof Peter Hotez MD PhD DSc(hon) @peterhotezmdphd.bsky.social · 17/04/2025journals.plos.org/plosbiology/... 89319
Reposted by Yue Hao 郝樾Floris Barthel @florisbarthel.bsky.social · 16/04/2025🚨 Pre-print alert! 🚨 We generated chromosome-scale diploid genome assemblies for the widely used fibroblast lines BJ and IMR-90. These models of replicative senescence and telomere shortening now have fully resolved telomeres, subtelomeres, and centromeres. 🧬 🧵👇 195