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Yue Hao 郝樾

@yuehao.bsky.social
195 followers 52 following 2 posts

Data Scientist & Applied AI Engineer. Former postdoc @MechofEvolution @ASUBiodesign 🌞🔱. #Bioinformatics PhD @NCState 🐺 and @Mizzou 🐯.

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Reposted by Yue Hao 郝樾
Daniel Bolnick @danielbolnick.bsky.social · 10/06/2026
I've been keeping this quiet for a while, but now's as good a time as any to announce: I have a book contract for a new textbook, Applied Evolutionary Medicine, with Princeton Univ Press. Core theme: "What, if anything, do medical practitioners do differently when they understand evolution"?
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Creight Photo 🌱☮️ @afewfromtheforest.bsky.social · 04/06/2026
(earth forests) #ThankfulThursday 📍Pennsylvania
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Gavin Conant @gavin-conant.bsky.social · 01/06/2026
Just posted a new pre-print on how buffering of cellular noise by changes in ploidy could be responsible for for hybrid vigor. I would be very interested in whether people find this a plausible idea or just "noise!" bioRxiv 2026.05.27.728238; doi: doi.org/10.64898/202...
doi.org
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Gavin Conant @gavin-conant.bsky.social · 18/05/2026
With the addition of a new 8-genome dataset for the grass Rho polyploidy, POInT Browse is now up to 13 polyploidies, 87 genomes and almost 1 million genes. Check it out: wgd.statgen.ncsu.edu
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Yue Hao 郝樾 @yuehao.bsky.social · 06/05/2026
Androgen loss accelerates brain tumour growth via HPA axis activation www.nature.com/articles/s41...
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Nucleic Acids Research @narjournal.bsky.social · 29/04/2026
⭐ #NARBreakthrough ⭐ New study delivers the first chromosome-level phased assemblies, uncovering >50,000 #structuralvariants and rescuing millions of #unmappable reads in BJ and IMR-90 human cell lines. 📖 Read here: doi.org/10.1093/nar/... #Genomics #CellLines #CommunityResource
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Yue Hao 郝樾 @yuehao.bsky.social · 01/04/2026
Gapless pangenome analyses reveal fast Brassica rapa subspeciation | Science www.science.org/doi/10.1126/...
science.org
Gapless pangenome analyses reveal fast Brassica rapa subspeciation
Brassica rapa (Br) encompasses many morphotypes and subspecies, so it is a good model with which to investigate plant diversification and subspeciation. Here, we resequenced the genomes of 1720 Br acc...
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Christian Landry @christianlandry.bsky.social · 23/03/2026
For those interested, the papers associated with my talk: pubmed.ncbi.nlm.nih.gov/39146405/ pubmed.ncbi.nlm.nih.gov/41699381/ pubmed.ncbi.nlm.nih.gov/36735790/ pubmed.ncbi.nlm.nih.gov/36050399/ pubmed.ncbi.nlm.nih.gov/41763210/ pubmed.ncbi.nlm.nih.gov/31454312/
pubmed.ncbi.nlm.nih.gov
Compensatory mutations potentiate constructive neutral evolution by gene duplication - PubMed
The functions of proteins generally depend on their assembly into complexes. During evolution, some complexes have transitioned from homomers encoded by a single gene to heteromers encoded by duplicate genes. This transition could occur without adaptive evolution through intermolecular compensatory …
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Graham Coop @gcbias.bsky.social · 12/03/2026
A fitting end to teaching speciation in the last week of undergrad evolution. Darwin 1858 March 11th, definitely was running on empty in week 10 of the quarter.
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Wouter De Coster @wdecoster.bsky.social · 12/03/2026
Thrilled to see our work from the past years finally published! We found a novel repeat expansion in the GOLGA8A gene in 60% of the aFTLD-U patients, a rare subtype of frontotemporal dementia. Huge thanks to all collaborators and patients for making this possible. www.nature.com/articles/s41...
nature.com
A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions - Nature Genetics
Genome-wide analysis coupled with long-read sequencing identifies a repeat expansion in GOLGA8A associated with high risk for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusi...
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Nature @nature.com · 10/03/2026
For the first time, researchers have simulated nearly every chemical reaction in a living bacterial cell go.nature.com/4lrAulM
go.nature.com
'Virtual cell' captures most-basic process of life: bacterial division
Researchers simulated nearly every molecule in a bacterial cell — and then watched the cell grow and reproduce.
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Wolfram Höps @wolfram-hops.bsky.social · 06/03/2026
🔄 Inversions predispose to recurrent deletions and duplications in chromsome 15q13.3. 🔁 Using de-novo assemblies of 10 patient-parent trios, we investigated how recurrent copy-number variants (CNVs) in the 15q13.3 locus arise. www.biorxiv.org/content/10.6... A brief tour (1/17)
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Gavin Conant @gavin-conant.bsky.social · 18/12/2025
Returning the page proofs for my quantitative biology textbook, out in February: www.routledge.com/Quantitative...
routledge.com
Quantitative Biology: Life from the Numbers
Biology at all scales has become a data-driven science, with large-scale datasets driving fields from population genomics to ecology. Practicing biologists have no choice but to use computational appr...
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Gavin Conant @gavin-conant.bsky.social · 31/10/2025
Congratulations to Lindsey Zanno of NC State and her collaborator for showing that what was thought to be a juvenile T. rex is actually a new species! www.nature.com/articles/d41...
nature.com
‘Teenage T. rex’ fossil is actually a different species
The discovery of smaller predator Nanotyrannus could prompt a re-think of tyrannosaur evolution.
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MILO Lab @milolab.bsky.social · 19/11/2025
If you are at #SNO2025 be sure to check @milolab.bsky.social talks and posters including a keynote talk by @heilandhenrik.bsky.social #Hawaii🏖️🌊 #glioblastoma
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J. Chris Pires @jchrispires.bsky.social · 03/08/2025
Traveled to Columbia, Missouri, to celebrate the successful #PhD defenses of my last two esteemed graduate students at the University of Missouri-Columbia! Michael Pisias (PhD Plant Biology, advised by Bing Yang); & Shawn K. Thomas (PhD Biology, co-advised by Jacob Washburn). #Crop #Evolution #agsky
Michael Pisias, Shawn Thomas, Chris Pires, standing in regalia at columns at University of Missouri-ColumbiaMichael Pisias and Shawn Thomas standing in regalia at columns at University of Missouri-ColumbiaShawn Thomas, Michael Pisias, and Chris Pires, having a fun photo in regalia at columns at the University of Missouri-Columbia
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 21/07/2025
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 18/06/2025
#SMBE2025 Symposium 4: Gene trees and beyond: genealogical methods and their applications in evolutionary genetics 🔗 smbe2025.scimeeting.cn/en/web/program/25070
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 22/04/2025
to really take your research to the next level, it is important to build interdisciplinary teams #collaboration #scientificinterfaces
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Tressie McMillan Cottom @tressiemcphd.bsky.social · 21/04/2025
The L.A. Times names THICK one of the best non-fiction books of the last 30 years. I will be honest with you, even I cannot always believe that this is my life. Thank you. Very much. www.latimes.com/entertainmen...
latimes.com
The 30 best nonfiction books of the last 30 years
To celebrate the 30th edition of the L.A. Times Festival of Books, we asked authors, editors, critics and scholars to select the 30 best nonfiction books since the festival was inaugurated.
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Prof Peter Hotez MD PhD DSc(hon) @peterhotezmdphd.bsky.social · 17/04/2025
journals.plos.org/plosbiology/...
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Floris Barthel @florisbarthel.bsky.social · 16/04/2025
🚨 Pre-print alert! 🚨 We generated chromosome-scale diploid genome assemblies for the widely used fibroblast lines BJ and IMR-90. These models of replicative senescence and telomere shortening now have fully resolved telomeres, subtelomeres, and centromeres. 🧬 🧵👇
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