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Jorge Vicente

@yorgsvicen.bsky.social
175 followers 168 following 1 posts

Junior Project Leader, Ramón y Cajal Fellow. Plants, pathogens and proteostasis at CNB-CSIC (Madrid)

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Reposted by Jorge Vicente
Gautier Langin @glangin.bsky.social · 11/09/2026
Preprint Alert! 🚨 Have you ever wondered how highly conserved molecular complexes adapted to ever changing cellular environments? Thrilled to show our work on 26S proteasome evolution in the green lineage. 🌱🧬👇 www.biorxiv.org/content/10.6... A thread🧵
biorxiv.org
Gene repertoire expansion and cis-regulatory diversification shaped 26S proteasome evolution within a proteostasis-centered network
The 26S proteasome is essential for proteostasis and constitutes one of the most conserved molecular machineries in eukaryotes. Its homeostasis is maintained by a mechanistically conserved feedback lo...
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Reposted by Jorge Vicente
Isa Manrique @isamanrique.bsky.social · 16/09/2026
Our paper is out! 🤩 HYT1, a new Cys2- substrate of the #Ndegron pathway to add to the list! 🌱 Thanks to @n-end-rules.bsky.social @charlene-kunaka.bsky.social @gunjansharma88.bsky.social , Susana and all the people involved in this work! You can read it on @natcomms.nature.com👇🏼
nature.com
Hierarchical regulation of oxygen-sensing through coupled transducers in Arabidopsis thaliana - Nature Communications
The PLANT CYSTEINE OXIDASE (PCO) N-degron pathway contributes to oxygen sensing in plants. Here the authors identify HYPOXIA TRANSDUCER1 (HYT1) as a substrate of PCO and show it forms a coherent feed-...
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Reposted by Jorge Vicente
N End Rules @n-end-rules.bsky.social · 16/09/2026
We introduce a new transducer of oxygen sensing: Cys2-HYT1 @isamanrique.bsky.social @charlene-kunaka.bsky.social Susanna Ubeda Tomas & @gunjansharma88.bsky.social ma88.bsky.social lead work defining HYT1 contribution to root hypoxia tolerance. @natcomms.nature.com www.nature.com/articles/s41...
nature.com
Hierarchical regulation of oxygen-sensing through coupled transducers in Arabidopsis thaliana - Nature Communications
The PLANT CYSTEINE OXIDASE (PCO) N-degron pathway contributes to oxygen sensing in plants. Here the authors identify HYPOXIA TRANSDUCER1 (HYT1) as a substrate of PCO and show it forms a coherent feed-...
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Reposted by Jorge Vicente
bioRxiv Plant Bio @biorxiv-plants.bsky.social · 27/07/2026
Functional diversification of UBP6 in plant immunity through N-degron pathway regulation www.biorxiv.org/content/10.64898/20…
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Reposted by Jorge Vicente
N End Rules @n-end-rules.bsky.social · 27/07/2026
New preprint: In collaboration with @yorgsvicen.bsky.social we show metacaspase9 and ATE N-degron pathway-dependent proteoform stability act to diversify UBP6 function during plant immunity www.biorxiv.org/content/10.6...
biorxiv.org
Functional diversification of UBP6 in plant immunity through N‑degron pathway regulation
Deubiquitylases are key proteolytic regulators of ubiquitin-dependent cellular processes, catalyzing the removal or remodelling of ubiquitin modifications on substrate proteins, including those target...
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Jorge Vicente @yorgsvicen.bsky.social · 27/07/2026
Our new preprint shows that metacaspase-mediated proteoform generation and N-degron pathway-dependent proteoform stability act together to diversify UBP6 function during Arabidopsis immunity www.biorxiv.org/content/10.6...
biorxiv.org
Functional diversification of UBP6 in plant immunity through N‑degron pathway regulation
Deubiquitylases are key proteolytic regulators of ubiquitin-dependent cellular processes, catalyzing the removal or remodelling of ubiquitin modifications on substrate proteins, including those target...
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Reposted by Jorge Vicente
bioRxiv Plant Bio @biorxiv-plants.bsky.social · 12/02/2026
Conditional stability of HY5 through the ATE N-degron pathway regulates environmental responses in Arabidopsis thaliana www.biorxiv.org/content/10.64898/20…
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Reposted by Jorge Vicente
N End Rules @n-end-rules.bsky.social · 12/02/2026
Surprisingly: "Conditional stability of HY5 through the ATE N-degron pathway regulates environmental responses in Arabidopsis thaliana". The shining bounds of N-degron pathway influence expands! @charlene-kunaka.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Jorge Vicente
Sjon Hartman @hartman-plantlab.com · 11/02/2026
We're recruiting a PhD student to try and understand stress memory and gene function, using gene editing, in trees! #plantscience
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Reposted by Jorge Vicente
N End Rules @n-end-rules.bsky.social · 22/11/2025
Recent advances in the mechanism, transduction and function of oxygen sensing in plants #nendrule #hypoxia #plantscience academic.oup.com/jxb/advance-...
academic.oup.com
Recent advances in the mechanism, transduction and function of oxygen sensing in plants
Abstract. Response to reduced ambient oxygen is a key component of plant adaptation in natural and farmed environments and is regulated by oxygen dependent
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Reposted by Jorge Vicente
Centro Nacional de Biotecnología (CNB) @cnb-csic.bsky.social · 17/11/2025
🌍Are you a young #bioscience researcher working abroad? Tell us about your research next 22 December at the #CNB_CSIC and @cbm-csic-uam.bsky.social  Joint meeting   ℹ️More info👇 f.mtr.cool/ndbdpkdsiu
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Reposted by Jorge Vicente
Centro Nacional de Biotecnología (CNB) @cnb-csic.bsky.social · 20/10/2025
🌍Are you a young #bioscience researcher working abroad? Tell us about your research next 22 December at the #CNB_CSIC and @cbm-csic-uam.bsky.social  Joint meeting   ℹ️More info👇 f.mtr.cool/ndbdpkdsiu
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Reposted by Jorge Vicente
Şuayb Üstün @suaybuestuen.bsky.social · 20/06/2025
Was super fun to present our recent work on protein translation and bacterial infection in the proteostasis session at #ICAR2025 Thanks to the organizers again!
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Reposted by Jorge Vicente
N End Rules @n-end-rules.bsky.social · 28/05/2025
How did oxygen-sensing evolve in plants? In collaboration with @syno2xis.bsky.social Great work from @lauradc.bsky.social et. al. #plantscience @leverhulme.ac.uk “ERFVIIs as transducers of oxygen-sensing in the evolution of land plant response to hypoxia” www.cell.com/molecular-pl...
cell.com
ERFVIIs as transducers of oxygen-sensing in the evolution of land plant response to hypoxia
Short summary:This study investigates the evolution of the low-oxygen response in land plants mediated by group VII Ethylene Response Factors (ERFVIIs). We identified conserved transcriptional signatu...
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Reposted by Jorge Vicente
bactodeath.bsky.social @bactodeath.bsky.social · 03/02/2025
Happy to share our new preprint on the role of the metacaspase AtMC1 in immunity: www.biorxiv.org/content/10.1...
biorxiv.org
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Reposted by Jorge Vicente
Centro Nacional de Biotecnología (CNB) @cnb-csic.bsky.social · 19/12/2024
Once again, we are hosting the Advances in Molecular Biology Workshop, welcoming young researchers working abroad. Throughout the day, we have enjoyed exciting talks and discussions. Additionally, we concluded the event with a round table featuring @nogaleslab.bsky.social (CNB-CSIC JAE Chair).
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Reposted by Jorge Vicente
Vinay Shukla @vinayshukla.bsky.social · 15/12/2024
Preprint alert, please share!! With our new study, we engineered an orthogonal hypoxia-responsive system in plants inspired by mammalian HIF protein degradation. We demonstrated that this system could control protein stability and activity, enabling modulation of Oxygen sensing outputs. Here's how:
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