Reposted by Jorge Vicente
Preprint Alert! 🚨
Have you ever wondered how highly conserved molecular complexes adapted to ever changing cellular environments?
Thrilled to show our work on 26S proteasome evolution in the green lineage. 🌱🧬👇
www.biorxiv.org/content/10.6...
A thread🧵
biorxiv.org
Gene repertoire expansion and cis-regulatory diversification shaped 26S proteasome evolution within a proteostasis-centered network
The 26S proteasome is essential for proteostasis and constitutes one of the most conserved molecular machineries in eukaryotes. Its homeostasis is maintained by a mechanistically conserved feedback lo...