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Wouter De Coster

@wdecoster.bsky.social
578 followers 238 following 114 posts

Dad. Scientist at VIB. Bioinformatics postdoc. Sequencing technologies enthusiastic. Geneticist. He/him.

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Wouter De Coster @wdecoster.bsky.social · 28/09/2026
Looking forward to using it to fill in a large, tedious list of co-authors
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Wouter De Coster @wdecoster.bsky.social · 28/09/2026
We, internationally, have failed so many people.
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Common Tern Project @commonternproject.bsky.social · 10/08/2026
Question: do I know anyone near Nantes who would be willing to pick up a dead gull-billed tern and its logger? L49 has sadly been killed near a road. I’d be very grateful for a picture and the logger and would of course reimburse postage.
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Wouter De Coster @wdecoster.bsky.social · 03/08/2026
I guess you could still send it to the authors and leave it up to them to improve their manuscript?
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Fritz Sedlazeck @sedlazeck.bsky.social · 26/06/2026
Four days, one whiteboard, forty open browser tabs, and against all odds, something that actually makes an impact in the field :). Hackathon @bcmhgsc.bsky.social Aug 25-28 Register:https://fritzsedlazeck.github.io/blog/2026/hackathon-2026/ @dnanexus.bsky.social @dcgenomics.bsky.social
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Wouter De Coster @wdecoster.bsky.social · 25/06/2026
Do you employ Bowerick Wowbagger perhaps?
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Wouter De Coster @wdecoster.bsky.social · 25/06/2026
Absolutely, looking forward :-)
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Wouter De Coster @wdecoster.bsky.social · 25/06/2026
Ported the aSTRonaut tool for visualizing tandem repeat sequence composition to Rust using the amazing kuva library from @psy-fer.bsky.social. Blog post at wdecoster.github.io/gigabaseorgi..., documentation at github.com/wdecoster/aS.... Feedback appreciated!
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Wouter De Coster @wdecoster.bsky.social · 24/06/2026
Done!
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Wouter De Coster @wdecoster.bsky.social · 23/06/2026
Oof that is bad
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George Conway ⚖️🇺🇸 @gtconway.bsky.social · 22/06/2026
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James Ferguson @psy-fer.bsky.social · 19/06/2026
kuva v0.3.0 release! - New raster backend: faster than the old one, dropped dep. - New QuiverPlot type - Pre-compiled release binaries (thanks @wdecoster.bsky.social ) - .parquet input for all CLI subcommands Also lots of fixes and other features crates.io/crates/kuva github.com/Psy-Fer/kuva
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Wouter De Coster @wdecoster.bsky.social · 15/06/2026
Congrats! The field is better because of you!
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bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 11/06/2026
inquiSTR: a toolkit for accurate and efficient population-scale tandem repeat genotyping and analysis www.biorxiv.org/content/10.64898/20…
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Wouter De Coster @wdecoster.bsky.social · 10/06/2026
Impressive, most impressive.
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Wouter De Coster @wdecoster.bsky.social · 08/06/2026
So this is how liberty dies...
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Wouter De Coster @wdecoster.bsky.social · 03/06/2026
THE WORST.
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Element Biosciences @elembio.bsky.social · 29/05/2026
🧬 Repeat expansions cause 50+ monogenic disorders and many workflows miss them. 🔬 See how we developed a PCR-free hybrid capture with Trinity™ to retain representation of repetitive loci, enabling accurate genotyping at these expansions on short-read platforms. Poster here: bit.ly/4oFuPZo
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Trish Greenhalgh @trishgreenhalgh.bsky.social · 23/05/2026
Every summer I repost this article on how to spot drowning. Please read it and pass on. In the last few years I’ve had SIX messages from people who saved a kid’s life after clicking on the link from my feed. slate.com/technology/2...
slate.com
Drowning Doesn’t Look Like Drowning
Drowning is not the violent, splashing call for help that most people expect.
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Wouter De Coster @wdecoster.bsky.social · 12/05/2026
They are just getting absolutely hammered by vibe-code adoption
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Wouter De Coster @wdecoster.bsky.social · 08/05/2026
It is an average. Not everyone has co-workers, some jobs are done alone?
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Wouter De Coster @wdecoster.bsky.social · 08/05/2026
Here you go :-)
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James Ferguson @psy-fer.bsky.social · 07/05/2026
kuva v0.2.0 Now over 60 plots! New plot types: Gantt, Network, Waffle, Horizon, PopulationPyramid, Joint, Clustermap, ROC, PR, Lollipop, Survival, Raincloud, Slope, Venn, Parallel, Mosaic, Streamgraph, Radar, Treemap, Sunburst, Bump, Funnel, Rose, Calendar, Legend, Text github.com/Psy-Fer/kuva
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Wouter De Coster @wdecoster.bsky.social · 05/05/2026
The year is 2026. It is now easier to vibe-rewrite a Python tool in Rust than to figure out how to get the dependencies installed.
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The Obama Foundation @obamafoundation.bsky.social · 04/05/2026
May the Fourth be with YOU, from the Obama Presidential Center. Opening June 19.
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Wouter De Coster @wdecoster.bsky.social · 23/04/2026
Oh, it starts to make sense now, the order of positions is relevant after all.
media.tenor.com
a man with glasses is surrounded by a glowing circle and the website pmitf.com is displayed below him
ALT: a man with glasses is surrounded by a glowing circle and the website pmitf.com is displayed below him
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Wouter De Coster @wdecoster.bsky.social · 23/04/2026
Sure, but one is "horizontal-vertical" (LeftTop), and the other is "vertical-horizontal" (TopLeft). So if I change the legend from inside to outside, it is not just changing Inside to Outside.
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Wouter De Coster @wdecoster.bsky.social · 22/04/2026
Hrm it is OutsideLeftTop and InsideTopLeft for the legend, it seems, is that intentional or just inconsistent?
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Wouter De Coster @wdecoster.bsky.social · 22/04/2026
Now, a sophisticated company like that is an offer you cannot refuse!
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Wouter De Coster @wdecoster.bsky.social · 20/04/2026
Very painful and late change
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Barry Butler Photography @barrybutler9.bsky.social · 19/04/2026
On this day in 2019, I witnessed one of the coolest things ever. A lenticular cloud lit-up by a setting sun over the Perito Morena Glacier in Argentina.
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Wouter De Coster @wdecoster.bsky.social · 01/04/2026
media.tenor.com
a man wearing sunglasses and a leather jacket is talking about scientists .
ALT: a man wearing sunglasses and a leather jacket is talking about scientists .
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James Ferguson @psy-fer.bsky.social · 31/03/2026
I got a little carried away making interactive plots using native SVG features. Then @jpelbers.bsky.social asked if it could run DOOM. It was probably a joke...but I took it as more of a challenge. Anyway. kuva doom -o doom.svg Fully playable and fully contained DOOM inside an SVG
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Wouter De Coster @wdecoster.bsky.social · 31/03/2026
Yup, can confirm.
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Wouter De Coster @wdecoster.bsky.social · 31/03/2026
Whoa, very cool indeed. Time to switch it seems!
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Wouter De Coster @wdecoster.bsky.social · 27/03/2026
I'm sorry, we can't really support that
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Wouter De Coster @wdecoster.bsky.social · 27/03/2026
The registration deadline for the Flanders Nanopore Day with @nanoporetech.com is quickly approaching, and the program suggests it will be an amazing event! All information is available at nanoporeflanders.be
nanoporeflanders.be
Flanders Nanopore Day 2026 - Flanders Nanopore Day
The Flanders Nanopore Day - April 17th, 2026
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Wouter De Coster @wdecoster.bsky.social · 26/03/2026
Deleting tasks is like a drug.
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Mariko Bennett @nachoriko.bsky.social · 24/03/2026
I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.
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Wouter De Coster @wdecoster.bsky.social · 24/03/2026
I would try something like the UltraMarathonRT rnaconnect.com/products/umr...
rnaconnect.com
uMRT Reverse Transcriptase Kit
UltraMarathonRT Reverse Transcriptase Kit is designed to meet the evolving needs of the RNA research community. It is an ultra-processive reverse transcriptase that uses a single pass to create cDNAs ...
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Wouter De Coster @wdecoster.bsky.social · 13/03/2026
I got absolutely ridiculed by our director when I brought up the concept at a departmental meeting nine years ago, as a PhD student.
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Wouter De Coster @wdecoster.bsky.social · 12/03/2026
Thrilled to see our work from the past years finally published! We found a novel repeat expansion in the GOLGA8A gene in 60% of the aFTLD-U patients, a rare subtype of frontotemporal dementia. Huge thanks to all collaborators and patients for making this possible. www.nature.com/articles/s41...
nature.com
A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions - Nature Genetics
Genome-wide analysis coupled with long-read sequencing identifies a repeat expansion in GOLGA8A associated with high risk for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusi...
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Wouter De Coster @wdecoster.bsky.social · 07/03/2026
"it depends"
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Harriet Dashnow @hdashnow.bsky.social · 06/03/2026
Wonder which tandem repeat genotyper to use on your Oxford Nanopore genomes? We benchmarked 7 tools on >100 ONT genomes. We assessed usability, assembly concordance, Mendelian consistency, and sensitivity to pathogenic expansions. www.biorxiv.org/content/10.6... 🖥️ 🧬 @cubiomedinfo.bsky.social
biorxiv.org
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Wouter De Coster @wdecoster.bsky.social · 03/03/2026
Hope you corrected it to 42.
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Wouter De Coster @wdecoster.bsky.social · 02/03/2026
Is this you?
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The Oatmeal @theoatmeal.bsky.social · 26/02/2026
We need to talk about naked mole rats theoatmeal.com/comics/naked...
theoatmeal.com
We need to talk about naked mole rats - The Oatmeal
This is a comic about naked mole rats, aka tube goblins.
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Keith @minguseyes.bsky.social · 24/02/2026
"The men implicated in the Epstein files reinforces that I spend half my life explaining to men that their simplified, optimistic view of other men doesn’t line up with the experience of women and girls trying to dodge sexual harassment, assault and abuse attempts." - Leslie Morgan Steiner
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James Ferguson @psy-fer.bsky.social · 22/02/2026
Building a new plotting library in pure Rust. Making themes and colourblind mode available on every plot type from day 1. What other accessibility options can I add?
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Wouter De Coster @wdecoster.bsky.social · 20/02/2026
Noooo not another tool to benchmark against :)
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