Reposted by Vitor Aguiar
How do genetic #riskvariants translate into cellular dysfunction in #autoimmunedisease?
Excited to share our latest preprint “Variant-to-function mapping in lupus links IL12A to the expansion of disease-associated B cells with a cytotoxic program”
www.medrxiv.org/content/10.6...
medrxiv.org
Variant-to-function mapping in lupus links IL12A to the expansion of disease-associated B cells with a cytotoxic program
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by over 200 risk variants identified through genome-wide association studies. While the majority of these are non-codin...
