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dl2409.bsky.social

@dl2409.bsky.social
245 followers 702 following 338 posts

Research/Teaching Genetics/Molecular Biology- DNA repair/ yeast

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Anne C. Hart @ach-ceneuro.bsky.social · 30/09/2026
Position available to work on Alternating Hemiplegia of Childhood; develop assays & test compounds using Hart lab #Celegans disease models. Ideal for scientist with Bachelors or Masters degree seeking mentorship, but previous at-the-bench experience is required. See REQ211438 on Brown Univ website.
C. elegans, various life stages
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dl2409.bsky.social @dl2409.bsky.social · 28/09/2026
They Kept Outsiders Away for 500 Years. Their World Is About to Change. www.nytimes.com/2026/09/23/m...
nytimes.com
They Kept Outsiders Away for 500 Years. Their World Is About to Change.
My father dedicated his life to studying the Guna people of Panama, and they may soon allow unprecedented development through their land. I went on a trek through the jungle to find out why.
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dl2409.bsky.social @dl2409.bsky.social · 28/09/2026
In an $80 Motel Room, a Discovery to Shed Light on the Origins of Life www.nytimes.com/2026/09/26/s...
nytimes.com
In an $80 Motel Room, a Discovery to Shed Light on the Origins of Life
A scrappy science project led to a significant discovery: two new species of a rare organism that could elucidate a fundamental transition in the history of life on our planet.
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Max Kozlov @maxkozlov.bsky.social · 25/09/2026
The bottom line? Academics have to contend with predatory journals, shoddy conferences, and now "deepfake prestige", as one of my sources called it. AI tools are only turbocharging this behavior and making it harder than ever to detect. Just as fast as one website goes down, another 10 can launch.
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Anna O. Law @unlawfulentries.bsky.social · 24/09/2026
There are multiple smaller departments and programs like Puerto Rican and Latinx Studies and Africana Studies in the same boat. Small numbers of faculty over-worked b/c essential committees still have to be staffed and tensions are high as morale is low. Different degrees of bleeding out.
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Annika Barber @annikabarber.bsky.social · 24/09/2026
My husband and I often comment that if it’s this difficult for two financially secure parents with graduate degrees, flexible schedules for calls & appointments, and reliable internet access & transportation to get our kids disability services- how does anyone less privileged succeed?
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dl2409.bsky.social @dl2409.bsky.social · 23/09/2026
www.nytimes.com/2026/09/19/w...
nytimes.com
Nepal’s Gen Z Is Taking on the World’s Polluters Over Climate Disasters
The young government of Nepal, a nation with a tiny carbon footprint, is seeking reparations from the world’s major economies as it bears the brunt of collapsing Himalayan glaciers.
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dl2409.bsky.social @dl2409.bsky.social · 17/09/2026
Finally!! After all these years. Someone is recommending “The Stench of Honolulu,” by Jack Handey! Great book-very funny! --> 👇 Anthony Jeselnik: Men Should Think of Reading as ‘Lifting Weights for Your Brain’ www.nytimes.com/2026/09/17/b...
nytimes.com
Anthony Jeselnik Explains Why He Started a Book Club
But the comedian isn’t naïve when he makes selections for his popular book club: “Most importantly, they’re short.”
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dl2409.bsky.social @dl2409.bsky.social · 15/09/2026
!!!!! 👇
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Edward Hopper @edwardhopper.bsky.social · 15/09/2026
Bridges were New York’s emblems before the skyline came to define the city. In Queensborough Bridge (1913), Hopper turned steel into a horizon as he studied how infrastructure shapes urban feeling.
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Kendra "Gloom is My Beat" Pierre-Louis @kendrawrites.com · 06/09/2026
Went to the Louis Armstrong house today and my god Louis loved music.
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Jeremy Berg @jeremymberg.bsky.social · 22/08/2026
I thought about this, but I am actually being kind. Jon was one of the leading proponents of programs to increase representation in the biomedical workforce when he was NIGMS Director but folded like a cheap umbrella early on. 1/4
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dl2409.bsky.social @dl2409.bsky.social · 22/08/2026
👇about Jon Lorsch, ex JHMI biophysics professor., NIGMS director, and current NIG Deputy director- a downward spiral !
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c0nc0rdance @c0nc0rdance.bsky.social · 12/08/2026
Her project involved combing the research literature for antioxidant substances found to decrease some of the cellular effects of aging: degenerative processes, early-stage steps toward cancer. She selected 33 of the top ones & in her high school science lab, dosed C. elegans roundworms with them.
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c0nc0rdance @c0nc0rdance.bsky.social · 12/08/2026
Let's talk about AOC as a young scientist & her award winning research on antioxidants & C. elegans, a standard roundworm model. She grew up in the Bronx. Ethnically Puerto Rican, her dad Sergio, an architect, died when she was 19. Her mother cleaned houses, drove a school bus. Working class.
Alexandria with her project for ISEF 2007.  A young woman with square glasses, she stands in front of a cardboard display recounting her work on antioxidants.
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Edward Hopper @edwardhopper.bsky.social · 08/08/2026
View Across Interior Courtyard at 48 rue de Lille, Paris - 1906 botfrens.com/collections/173/conten…
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Elizabeth Spiers @espiers.bsky.social · 07/08/2026
As anyone in publishing will tell you, women do not resist reading books by men, but men will often dismiss books by women. This is not a publishing problem or a failure to target men. It's a misogyny problem.
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ANCOR @therealancor.bsky.social · 06/08/2026
Today, the Senate Homeland Security & Governmental Affairs Committee voted the Recognizing the Role of DSPs Act unanimously out of committee. Help us keep up the momentum. Take action today & ask your members of Congress to support the direct support workforce!
ancor.org
Tell Congress to Support the Recognizing the Role of DSPs Act | ANCOR
The bipartisan Recognizing the Role of Direct Support Professionals Act urges the Office of Management and Budget to establish a Standard Occupational Classification (SOC) for direct support professio...
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dl2409.bsky.social @dl2409.bsky.social · 03/08/2026
10-Minute Challenge: ‘A Sunday on La Grande Jatte’ www.nytimes.com/interactive/...
nytimes.com
10-Minute Challenge: ‘A Sunday on La Grande Jatte’
We’d like you to look at one piece of art for 10 minutes, uninterrupted.
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Melissa Toups @meltoups.bsky.social · 30/07/2026
My university has kept the 1990 ratio by paying our PhD students less than I made 18 years ago as a grad student. Not great!
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Flo Débarre @flodebarre.eurosky.social · 29/07/2026
I will be following Anthony Fauci's hearing today, and I will post comments in this thread with the hashtag #faucihearing. Feel free to mute it! ▫️1/🧵 www.hsgac.senate.gov
screenshot of the HSCA Committee on Upcoming Hearings
Full Committee Hearing
Testimony of Anthony Fauci
July 29th, 2026
at
8:30am
Senate Dirksen Building, SD-342
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Rep. Ilhan Omar @repilhan.bsky.social · 23/07/2026
Proud to lead a statement with 10 of my colleagues to condemn the State Department’s attack on Americans’ free speech rights and collective punishment of Cubans: 🧵
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dl2409.bsky.social @dl2409.bsky.social · 23/07/2026
Deep in This Lake, a Contagious Cancer Is Spreading www.nytimes.com/2026/07/22/s...
nytimes.com
Deep in This Lake, a Contagious Cancer Is Spreading
Transmissible tumors have been reported in a handful of animal species, but never before among fish. Is it possible in humans?
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dl2409.bsky.social @dl2409.bsky.social · 11/07/2026
Which Version of the ‘Odyssey’ Should You Read? www.nytimes.com/video/books/...
nytimes.com
Video: Which Version of the ‘Odyssey’ Should You Read?
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Rachael French @drrachaelf.bsky.social · 24/06/2026
Yesterday, I submitted a request for a raise for one of my staff. (actually, I submitted the justification for a raise to my Dean’s office and they submitted the request to personnel). I’ve got another one in the works.
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Karolin Luger @nucleosomepolice.bsky.social · 20/06/2026
Please share this gift article from The New York Times with friends, family, sceptics, and People who think that studying weird things is a waste of money. Then follow up with meaningful discussion about what I call 'free range science'. Free without subscription. www.nytimes.com/2026/06/20/o...
nytimes.com
Opinion | The Science That Turned Lizard Venom Into GLP-1s Is Under Attack
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Ashley Juavinett, PhD @ashleyjuavinett.bsky.social · 19/06/2026
omg are the USA men good now welcome, we’ve been waiting
static.klipy.com
Alex Morgan's Iconic Tea Celebration
ALT: Alex Morgan's Iconic Tea Celebration
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Jase Gehring @skyjase.bsky.social · 17/06/2026
they even got the gradients right by pouring the H2O2 in from the side. it's a giga-plate fr @baym.lol is seeing his vision fully realized
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Claude Monet @monet.bsky.social · 16/06/2026
Weeping Willow - 1918 botfrens.com/collections/41/content…
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Claude Monet @monet.bsky.social · 13/06/2026
San Giorgio Maggiore at Dusk - 1908 botfrens.com/collections/41/content…
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Claude Monet @monet.bsky.social · 13/06/2026
Rouen Cathedral - 1892 botfrens.com/collections/41/content…
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Michael Okun @michael-okun.bsky.social · 10/06/2026
I’ve officially resigned as Associate Editor for Frontiers in Systems Neuroscience. It used to be a reputable journal, but became a case study in how forced automation destroys academic integrity. 👇
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dl2409.bsky.social @dl2409.bsky.social · 11/06/2026
Trump’s Assaults on Scientific Research Just Got Worse www.nytimes.com/2026/06/09/o...
nytimes.com
Opinion | Trump’s Assaults on Scientific Research Just Got Worse
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dl2409.bsky.social @dl2409.bsky.social · 03/06/2026
a bit of History...
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David Ho @davidho.bsky.social · 13/05/2026
Like I said, NSF is disbursing funds but awarding very few grants. This means big projects with established PIs are benefiting, and early-career scientists are suffering. This is how US science dies.
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Craig Kaplan @triggerloop.bsky.social · 13/05/2026
Everyone should ask the Congressional representatives why they don’t want to fund cancer research when they allow mRNA vaccines to be snuffed out. Promising new small study on mRNA vaccine for breast cancer
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Mark Peifer (He, him) @peiferlabunc.bsky.social · 13/05/2026
While BioNtech & Moderna become household names because of their Covid vaccines, those emerged from different projects: finding ways to treat the most challenging cancers. They hypothesized that we could vaccinate patients against their own tumors, & evidence is mounting that they were right! 1/n 🧪
https://www.nature.com/articles/s41586-025-10004-2
Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC

    U. Sahin, M. Schmidt, E. Derhovanessian, A. Cortini, I. Vogler, T. Omokoko, E. Godehardt, S. Attig, S. Newrzela, J. Grützner, N. Bidmon, S. Bolte, S. Brachtendorf, T. Stuhlmann, D. Langer, D. Brüne, J. Blake, A. Feldner, H. Lindman, A. Schneeweiss, M. Eichbaum & Ö. Türeci 
Triple-negative breast cancer (TNBC) is frequently associated with metastatic relapse, even at an early stage1. Here we assessed an individualized neoantigen mRNA vaccine in 14 patients with TNBC following surgery and after neoadjuvant or adjuvant therapy. In peripheral blood of nearly all patients, high-magnitude, vaccine-induced, mostly de novo T cell responses to multiple neoantigens were detected that remained functional for several years. Characterization of individual patients revealed that a large proportion of these T cells developed into two subsets: a late-differentiated phenotype with markers indicative of ‘ready-to-act’ cytotoxic effector T cells, and T cells with a stem cell-like memory phenotype. Eleven patients remained relapse-free for up to six years post-vaccination. Recurrence occurred in three patients: the individual with the weakest vaccine-induced T cell response relapsed, but achieved complete remission on subsequent anti-PD-1 therapy; another patient had a tumour with low major histocompatibility complex (MHC) class I expression with MHC class I-deficient cells growing out under vaccination; and the third patient was BRCA-positive and had a recurrence from a genetically distinct primary tumour. These findings demonstrate the feasibility of individualized RNA vaccines in TNBC, document persistence of vaccine-induced, functional neoantigen-specific T cells and provide insights into possible immune escape mechanisms that will guide future approaches.
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dl2409.bsky.social @dl2409.bsky.social · 12/05/2026
Transformer/Nick Lane is a fantastic book!
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Nathaniel Comfort @nccomfort.bsky.social · 12/05/2026
this is great, thanks. Have you read Transformer? Lane has a really interesting model of how the TCA cycle could evolve from abiotic reactions and how it would flip to the Krebs cycle & CO2 fixation as O2 levels rise (hope i’m not mangling that; sitting in dentist’s office!).
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Claude Monet @monet.bsky.social · 12/05/2026
Red Boats at Argenteuil - 1875 botfrens.com/collections/41/content…
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dl2409.bsky.social @dl2409.bsky.social · 07/05/2026
It’s not that the NIH was “imperfect”- it is- was- a well thought out,well ran and excellently functioning institution. The only problem: it was not adequately funded, by a lot.That’s not imperfect. It’s: not supported as it should have been
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Claude Monet @monet.bsky.social · 28/04/2026
Lunch on the Grass (central panel) - 1865/1866 botfrens.com/collections/41/content…
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Don Moynihan @donmoyn.bsky.social · 28/04/2026
I know we get inured to stuff, but it is hard to fathom the cruelty here. At a time of tax cuts for the most powerful, they are trying to remove basic supports for the most vulnerable. The Trump administration's war on people with disabilities continues.
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dl2409.bsky.social @dl2409.bsky.social · 28/04/2026
😀DOA stands for “degradation of alpha” : mutants that do not degrade Matalpha2 upon switching from alpha to a: yeast cell bio!! Apoyg!!
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Craig Kaplan @triggerloop.bsky.social · 27/04/2026
Look at this crazy thing
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dl2409.bsky.social @dl2409.bsky.social · 25/04/2026
On the NSF- an (other) absolute shame that this administration is responsible for-
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Claude Monet @monet.bsky.social · 25/04/2026
Étretat: The Beach and the Falaise d'Amont - 1885 botfrens.com/collections/41/content…
Gift of Mrs. John H. (Anne R.) Winterbotham in memory of John H. Winterbotham; Joseph Winterbotham Collection
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