Eli Van Allen @vanallenlab.bsky.social · 07/05/2025Relatedly - there really is *so much* to be optimistic about, regularly inspired by folks like Jett who will improve the way we care for people everywhere 020
Eli Van Allen @vanallenlab.bsky.social · 07/05/2025Thinking about the way of the world, a chat ~25 years ago about a new camp for kids whose parents have cancer, and (soon-to-be) Dr. Jett Crowdis today He shares his motivations in medicine, the link to Camp Kesem, and our science in @harvard.edu Gazette news.harvard.edu/gazette/stor...news.harvard.eduThe boy had just lost his dad to cancer. Jett Crowdis listened. — Harvard GazetteHarvard Medical School graduate found his calling in a connection forged while serving as a camp counselor. 290
Eli Van Allen @vanallenlab.bsky.social · 15/04/2025In this perspective, we examined the present and future interface of AI & translational cancer research for @cp-cancercell.bsky.social - led by the stellar Dr. Josephine Yates! @danafarber.bsky.social @broadinstitute.org www.sciencedirect.com/science/arti...sciencedirect.comNew horizons at the interface of artificial intelligence and translational cancer researchArtificial intelligence (AI) is increasingly being utilized in cancer research as a computational strategy for analyzing multiomics datasets. Advances… 062
Eli Van Allen @vanallenlab.bsky.social · 10/02/2025Thanks @danafarber.bsky.social @broadinstitute.org for the uniquely supportive + collaborative environments to pursue this work, NIH / NCI / PICI / Novartis + more for the research funding, & most importantly to the patients who continue to inspire by agreeing to these research programs... 030
Eli Van Allen @vanallenlab.bsky.social · 10/02/2025Here's our latest - jointly with @rhaq1.bsky.social lab & co-lead by Drs. Schiantarelli, Benamar, Park et al - studying why some tumors stop responding to immunotherapy. This continues to be a tough puzzle to solve, but important for science & patients alike... 1184
Reposted by Eli Van AllenVijay G. Sankaran @bloodgenes.bsky.social · 08/02/2025While on clinical service recently, I saw many children who were severely ill due to cancer, flu, and other causes. Sadly this move will mean that healthcare access for many children will be lost, as our institutions suffer from the loss of this critical support: grants.nih.gov/grants/guide...grants.nih.govNOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost RatesNIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD 0368
Eli Van Allen @vanallenlab.bsky.social · 02/01/2025Tons of team science here, based on data from heroic kids + their families... Also...check out Riaz's new lab (website): gillanilab.dana-farber.org + Ryan's original tweetorial on the preprint: x.com/RyanLCollins... + @danafarbernews.bsky.social press release: www.dana-farber.org/newsroom/new...gillanilab.dana-farber.orgGillani Lab - Computational Pediatric Cancer ResearchGillani Lab - Computational Pediatric Cancer Research 010
Eli Van Allen @vanallenlab.bsky.social · 02/01/2025Here's our latest, led by Drs. Riaz Gillani & Ryan Collins - we studied a type of inherited genetic event (structural variants) + risk of developing certain cancers in kids: @danafarber.bsky.social @bostonchildrens.bsky.social @broadinstitute.org @science.org www.science.org/doi/10.1126/...science.orgRare germline structural variants increase risk for pediatric solid tumorsPediatric solid tumors are a leading cause of childhood disease mortality. In this work, we examined germline structural variants (SVs) as risk factors for pediatric extracranial solid tumors using ge... 34719
Reposted by Eli Van AllenDerek Thompson @dkthomp.bsky.social · 21/12/2024People sometimes make fun of science that sounds stupid and random. Meanwhile, a study of lizard saliva turned into a peptide medication, which was turned into a diabetes medication, which was turned into a GLP1 weight loss drug, that just became the first therapy every approved for … sleep apnea 372171775071
Reposted by Eli Van AllenMolecular Oncology Almanac @moalmanac.org · 06/12/2024Our December knowledge base release is now out! With these two recent FDA approvals, we now have curated over 1,000 records🥳 Explore through our browser at moalmanac.org 031
Eli Van Allen @vanallenlab.bsky.social · 04/12/2024Congrats to Larry, Aram et al on latest prostate cancer immunology effort, now out in @natureportfolio.bsky.social - fun collaboration + more to come! @danafarber.bsky.social @ucsfcancer.bsky.social www.nature.com/articles/s41...nature.comEvolution of myeloid-mediated immunotherapy resistance in prostate cancer - NatureSingle-cell profiling of human prostate cancer and studies in mouse models show that macrophages expressing SPP1 mediate immunotherapeutic resistance through adenosine pathway activation and repr... 0224
Reposted by Eli Van AllenMolecular Oncology Almanac @moalmanac.org · 25/11/2024Hello world! We're a paired knowledge base and algorithm for precision cancer medicine, based out of the @vanallenlab.bsky.social within @danafarber.bsky.social in #Boston #MA. You can learn more about us at moalmanac.org!moalmanac.orgThe Molecular Oncology Almanac 071
Reposted by Eli Van AllenSasha Gusev @sashagusevposts.bsky.social · 24/11/2024I wrote about the National Institutes of Health and the various serious and unserious proposals for NIH reform that have been floating around. It is important to understand how this agency actually functions and point criticism at the right problems. A short 🧵:open.substack.comDistinguishing real from invented problems with the NIHHow does the NIH work and where does it work well? 614367
Eli Van Allen @vanallenlab.bsky.social · 20/10/2023Great panel on AI in cancer research at the US Senate, led by Ned Sharpless and organized by Senators Rounds, Schumer, Heinrich, and Young - key engagement & thoughts from the organizers and other Senators, and a chance to share our exciting work at Dana-Farber and beyond! 051
Eli Van Allen @vanallenlab.bsky.social · 22/09/2023Here, we built biologically interpretable computer vision models for H&E + mIF images to learn key tumor and immune microenvironmental states in kidney cancer that also inform immunotherapy response - congrats Drs. Nyman, Signoretti, Choueiri et al! www.cell.com/cell-reports... 061
Eli Van Allen @vanallenlab.bsky.social · 19/09/2023Rarely are my LA childhood/living experiences helpful around here, but I just talked someone starting a lab in Children's Hospital LA out of "living by the beach and commuting to that part of Sunset" Feels like I did something important, still shook by the potential catastrophe 030