Sign in

MRC Integrative Epidemiology Unit

@uob-ieu.bsky.social
221 followers 121 following 55 posts

MRC Integrative Epidemiology Unit at @bristoluni.bsky.social uses genetics, population data & experimental interventions to look for causes of chronic disease. bristol.ac.uk/ieu

PostsRepliesMedia
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 25/08/2026
Antidepressant use in pregnancy linked to small increases in some birth risks, but absolute increase in risk is still small. www.bristol.ac.uk/integrative-...
bristol.ac.uk
2026: Antidepressant use in pregnancy linked to small increases in some birth risks | MRC Integrative Epidemiology Unit | University of Bristol
000
Reposted by MRC Integrative Epidemiology Unit
George Davey Smith @mendelrandom.bsky.social · 22/07/2026
Does the (live) shingles vaccine protect against dementia? Fergus Hamilton and colleagues provide important evidence in a new preprint using hospital data from the whole of England in a regression discontinuity design from which we *don't* show evidence of a meaningful protective effect /cont
38245
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 10/07/2026
A team of researchers will be at @merthyrscience.bsky.social tomorrow, with fun activities and opportunities to comment on real research. If you are in the area do come and say hello!
A ball pool full of little fabric people in different colours, with a magnetic fishing rod on top.
000
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 01/07/2026
If you are local to Bristol do come along to Keynsham Music Festival on Saturday. We'll be part of a brand-new "Discovery Zone" science area at this free, community festival. Come to see us and become a "Health data detective"! keynshammusicfestival.co.uk/futures-disc...
A white tent under a tree, with two people standing in the foreground. Around the tent are a range of fun activities for people to do and learn about.
000
Reposted by MRC Integrative Epidemiology Unit
Amanda (Mandy) Hughes @ammhughes.bsky.social · 19/06/2026
Our new paper in BMJ Public Health finds being bullied at work predicts long-term weight gain. Adds to evidence that workplace bullying harms health and strengthens the case for regulatory measures to tackle it. With @domignon.bsky.social @uob-ieu.bsky.social bmjpublichealth.bmj.com/content/4/2/...
bmjpublichealth.bmj.com
Body mass index and workplace bullying: exploring causality in two general population Norwegian surveys, the HUNT study and the Norwegian Mother, Father and Child Cohort Study (MoBa)
Introduction To interrogate whether reported associations between body mass index (BMI) and workplace bullying (WPB) reflect an impact of weight on bullying, an impact of bullying on weight or confoun...
022
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 03/06/2026
How is blood clot risk associated with cancer DNA? This is a question that Naomi Cornish and colleagues are helping to answer. Watch this short animation to learn more. www.youtube.com/watch?v=DzRY... @wellcometrust.bsky.social
youtube.com
Tumour genetic risks for cancer-associated thrombosis
YouTube video by MRC IEU at University of Bristol
010
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 26/05/2026
A new pilot trial shows promise for using anti-inflammatory treatment for treament-resistant depression. ieureka.blogs.bristol.ac.uk/2026/05/21/i...
A grey teddy bear, wearing a face mask and cuddling a white and grey spotty blanket. In front of the bear are bottles and packs of pills and a stethoscope. Photo by Myriam Zilles on Unsplash.
010
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 20/05/2026
Congratulations to @eimearfoley.bsky.social and colleagues on this important new paper, which suggests that an anti-inflammatory drug commonly used for rheumatoid arthritis could help difficult-to-treat depression. www.bristol.ac.uk/news/2026/ma...
bristol.ac.uk
May: pilot-trial-suggests-anti | News and features | University of Bristol
012
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 20/05/2026
If you are at Merthyr Science Festival on 11th July do come and say hello to our team. There will be a range of fun activities to give you a taste of how looking at health information from lots of people helps us learn what makes us sick or well.
010
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 19/03/2026
This week IEU's Dr David Hill was a guest on The Last Show podcast. David was talking about his research into socioeconomic status and brain health in later life. podcasts.apple.com/ca/podcast/s...
podcasts.apple.com
Socioeconomic Status Alters Your Brain Structure
Podcast Episode · The Last Show with David Cooper · March 18 · 11m
100
Reposted by MRC Integrative Epidemiology Unit
George Davey Smith @mendelrandom.bsky.social · 18/03/2026
A comprehensive new tool for exploring how genetic variation influences outcomes, of relevance to everything driven by phenotypes, which encapsulates many domains, from how drugs work to how natural selection works ... / cont
183
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 16/03/2026
The Human Genotype-Phenotype Map is an integrated discovery engine designed to help genetic epidemiologists move from a list of SNPs to a systemic understanding of pleiotropic architecture. Read more in @elmorea.bsky.social's blog post: ieureka.blogs.bristol.ac.uk/2026/03/11/g...
ieureka.blogs.bristol.ac.uk
A Guide to The Genotype-Phenotype Map – IEUREKA!
041
Reposted by MRC Integrative Epidemiology Unit
jasminekhouja.bsky.social @jasminekhouja.bsky.social · 12/03/2026
Before the UK‑wide disposable vape ban, we asked 22 young adults who used disposables about the ban and how they might respond. Some reactions were expected, others were more concerning: “I’d probably start smoking." Read more about our latest study, led by Richie Carr: doi.org/10.1371/jour...
031
Reposted by MRC Integrative Epidemiology Unit
Adlung Lab @adlunglab.com · 05/02/2026
Higher BMI from menarche to age 40 protects against breast cancer, but this effect attenuates when controlling for prepubertal adiposity, write Power et al. from @uob-ieu.bsky.social in @science.org Advances www.science.org/doi/... 🧪
022
Reposted by MRC Integrative Epidemiology Unit
Sophie Jade Fairweather @sjfairweather.bsky.social · 05/02/2026
Our systematic review highlights a lack of robust models to forecast future risk of persistent or worsening anxiety and depression, especially in child/adolescent populations where there is opportunity for early intervention. Read: tinyurl.com/h7vjzjch @bristolbrc.bsky.social @uob-ieu.bsky.social
tinyurl.com
Prediction models for longitudinal trajectories of depression and anxiety: a systematic review
Prediction of atypical health trajectories may enable early intervention. We systematically reviewed the existing literature on models for predicting …
032
Reposted by MRC Integrative Epidemiology Unit
NIHR Biomedical Research Centre: Bristol @bristolbrc.bsky.social · 09/02/2026
📢 New research paper! 🫂Our review shows there's a lack of risk calculators to predict long-term #depression and #anxiety 👉 www.bristolbrc.nihr.ac.uk/review-finds... #MentalHealth #MentalHealthResearch @sjfairweather.bsky.social @uob-ieu.bsky.social
bristolbrc.nihr.ac.uk
Review finds lack of risk calculators to predict long-term depression and anxiety - Bristol Biomedical Research Centre
There are very few risk calculators to predict how symptoms of anxiety and depression will change over the course of a person’s life, according to a recent review of past research. This is the first s...
034
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 02/02/2026
We are excited today for the start of the new Obesity-related Cancer Epidemiology Programme, funded by @cancerresearchuk.org. Read more in our news story: www.bristol.ac.uk/integrative-...
bristol.ac.uk
2026: OCEP launch | MRC Integrative Epidemiology Unit | University of Bristol
142
Reposted by MRC Integrative Epidemiology Unit
George Davey Smith @mendelrandom.bsky.social · 26/01/2026
Brilliant inaugural lecture by Professor Evie Stergiakouli on her career so far, @uob-ieu.bsky.social so lucky to have secured her talents right from its inception. Thx Evie!
0102
Reposted by MRC Integrative Epidemiology Unit
fmberstein.bsky.social @fmberstein.bsky.social · 14/01/2026
We found that higher maternal blood pressure increases the risk of multiple adverse pregnancy outcomes, highlighting the importance of interventions aimed at controlling blood pressure in the population. Check out this press release for more details: www.bristol.ac.uk/news/2026/ja...
bristol.ac.uk
January: Higher maternal blood pressure increases the risk of pregnancy complications | News and features | University of Bristol
121
Reposted by MRC Integrative Epidemiology Unit
fmberstein.bsky.social @fmberstein.bsky.social · 14/01/2026
After five years of collaboration with the MR-Preg group, I'm excited to share our latest Mendelian randomization study on maternal blood pressure during pregnancy and perinatal health, published today in BMC Medicine 🎉 Thanks to all those involved! rdcu.be/eY0nB
102
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 15/01/2026
Newspaper headlines often share compelling quick fixes for health issues - but often the realities of what causes health conditions is more complex. In this blog post @mendelrandom.bsky.social explains why he encourages scientists to look for ways they might be wrong. www.ukri.org/blog/why-evi...
ukri.org
Why evidence matters in health research
Professor George Davey Smith explains why he encourages scientists to look for ways they might be wrong.
053
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 05/01/2026
Happy New Year! To start the year, do read this @ukri.org interview with our director @mendelrandom.bsky.social, recipient of the prestigious MRC Millennium Medal. medium.com/@UKRI/why-co...
medium.com
Why ‘coffee causes cancer’ headlines get it wrong
Coffee causes cancer. Red wine protects your heart. Chocolate cuts diabetes risk. These headlines catch the eye, but are they true?
051
Reposted by MRC Integrative Epidemiology Unit
GW4-CAT HP @gw4cat.bsky.social · 27/11/2025
Congratulations Professor George Davey Smith on being awarded the Medical Research Council Millennium Medal @uob-ieu.bsky.social @bristoluni.bsky.social, @ukri.org
051
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 17/11/2025
Many congratulations to IEU's Director, Professor George Davey Smith. This week he is being awarded the prestigious Medical Research Council Millennium Medal. @childrenofthe90s.bsky.social @bristoluni.bsky.social @ukri.org www.bristol.ac.uk/news/2025/no...
bristol.ac.uk
November: MRC Millennium Medal awarded to preeminent British health scientist from Bristol | News and features | University of Bristol
030
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 17/11/2025
Many congratulations to IEU's Director, Professor @mendelrandom.bsky.social. This week he is being awarded the prestigious Medical Research Council Millennium Medal. @childrenofthe90s.bsky.social @bristoluni.bsky.social www.bristol.ac.uk/news/2025/no...
bristol.ac.uk
November: MRC Millennium Medal awarded to preeminent British health scientist from Bristol | News and features | University of Bristol
010
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 14/11/2025
Huge congratulations to our director @mendelrandom.bsky.social on this prestigious medal, which MRC is awarding to him next week.
020
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 13/11/2025
IEU is again represented strongly in the latest Clarivate Highly Cited Researcher awards. Congratulations to the nine IEU researchers in the latest list (over a thousanth of all the awards). clarivate.com/highly-cited...
clarivate.com
Clarivate Highly Cited Researchers 2025
The Highly Cited Researchers 2025 list identifies and celebrates individuals who have demonstrated significant and broad influence in their fields of research. Through rigorous selection criteria and ...
021
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 29/10/2025
As the clocks changed last weekend, the Daily Mail published an article about the health impacts of these twice-yearly changes, including an interview with IEU's @meldelange.bsky.social www.dailymail.co.uk/sciencetech/...
dailymail.co.uk
Scientists call for the clock change to be DITCHED entirely
In the early hours of tomorrow morning the clocks will jump back an hour. But rather than celebrate having a lie-in, experts have warned it could have a slew of negative consequences.
011
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 10/10/2025
Cholesterol-lowering drugs could reduce the risk of dementia, study finds - read about this important new research from the MRC Integrative Epidemiology Unit www.bristol.ac.uk/news/2025/oc...
bristol.ac.uk
October: Cholesterol dementia study | News and features | University of Bristol
020
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 24/09/2025
How fat is distributed in people’s bodies could make a difference to their risk of certain cancers. Read more in our latest press release. www.bristol.ac.uk/news/2025/se...
bristol.ac.uk
September: Adiposity and cancer | News and features | University of Bristol
011
Reposted by MRC Integrative Epidemiology Unit
Gemma Taylor @gemmamjtaylor.bsky.social · 02/09/2025
Share: Complete your PhD in data science & epidemiology with real-world impact! Join us at @uob-ieu.bsky.social @bristoluni.bsky.social through the @gw4biomeddtp.bsky.social. Fully funded project exploring biological mechanisms linking smoking & mental health. gw4biomed.ac.uk/what-are-the...
gw4biomed.ac.uk
What are the biological mechanisms underlying the association between smoking, smoking cessation and mental health: a triangulation approach - GW4 BioMed MRC DTP
Project Code MRCPHS26Br Taylor G Project Type Dry lab Research Theme Population Health Science Project Summary Download Summary What are the biological mechanisms underlying the association between sm...
035
Reposted by MRC Integrative Epidemiology Unit
Gemma Taylor @gemmamjtaylor.bsky.social · 02/09/2025
Share: Complete your PhD in data science & epidemiology with real-world impact! Join us at @uob-ieu.bsky.social @bristoluni.bsky.social through the @gw4biomeddtp.bsky.social. Fully funded project exploring co-use of e-cigarettes, cannabis and tobacco gw4biomed.ac.uk/understandin...
054
Reposted by MRC Integrative Epidemiology Unit
NIHR Biomedical Research Centre: Bristol @bristolbrc.bsky.social · 11/09/2025
💡 New research paper! Can we find new ways to treat serious lung disease? 🫁 Higher levels of interleukin-6 in patients with pleural infection are linked to more serious disease 🤒 www.bristolbrc.nihr.ac.uk/higher-level... @uob-ieu.bsky.social @nihrexeterbrc.bsky.social @bristolaru.bsky.social
bristolbrc.nihr.ac.uk
Higher levels of interleukin-6 in patients with pleural infection are linked to more serious disease - Bristol Biomedical Research Centre
Patients with a pleural infection who have higher levels of interleukin-6 in their blood or pleural fluid are likely to be more unwell than patients with lower interleukin-6 levels, a new study shows....
111
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 01/09/2025
Do you have strong research software engineering skills who wants to make a real-world impact? We are looking for a Senior Research Associate/Research Fellow in Genetic Epidemiology Research (Software Engineer). Apply by 14th September. www.bristol.ac.uk/jobs/find/de...
bristol.ac.uk
Details | Working at Bristol | University of Bristol
021
Reposted by MRC Integrative Epidemiology Unit
Medical Research UK @medicalresearchuk.bsky.social · 29/08/2025
🧁🧬 Great British Bake Off finalist @joshpsmalley.bsky.social joined @lpaternoster.bsky.social to turn her genetic research into delicious vanilla & passionfruit cupcakes - with a scientific twist. 🎥 Watch the full video here: youtu.be/xcc200LksM4?... @bristolbrc.bsky.social @uob-ieu.bsky.social
youtu.be
Explaining science through baking with Bake Off finalist Josh Smalley and Dr Paternoster
YouTube video by Medical Research Foundation
011
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 27/08/2025
New Scientist cover story! Latest issue puts a spotlight on the work of Golam Khandaker & others in our Immunopsychiatry programme, as well as other groups, in uncovering links between inflammation & mental health. @childrenofthe90s.bsky.social www.newscientist.com/article/2491...
newscientist.com
Chronic inflammation messes with your mind. Here's how to calm it
From depression to dementia, we are now realising the profound impacts of long-term inflammation on the brain. A better understanding of the underlying mechanisms is unlocking new treatments to protec...
033
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 18/08/2025
We've just come back from a great weekend at the Green Man Festival. Weather was lovely, music was great and we had a great time talking with ~1500 people about what health research questions they would like answers to. Lots of reflections to share - once we've finished unpacking and sleeping!
Images shows pieces of white fabric with handwriting and pictures on it, hanging from string in a tree on a sunny day. This is research question bunting. The writing cannot be easily read in this image because the bunting was blowing in the wind but the bunting represents questions about health that people would like there to be research on. Popular themes included women's health, diet and mental health.
000
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 12/08/2025
If you are at the Green Man Festival at the weekend come and visit us in Einstein's Garden! We have a range of activities to demonstrate how to be an epidemiologist. www.bristol.ac.uk/integrative-...
bristol.ac.uk
2025: Green Man 2025 | MRC Integrative Epidemiology Unit | University of Bristol
010
Reposted by MRC Integrative Epidemiology Unit
Éimear M. Foley @eimearfoley.bsky.social · 09/07/2025
Yesterday, I officially graduated with a PhD in Immunopsychiatry from the @uob-ieu.bsky.social @bristoluni.bsky.social 🎉 🎓 An incredibly special (and sunny!) day spent celebrating with friends and family. A huge thank you to my parents, siblings, supervisors, and all those supporting from afar ❤️
Three people standing under a sign reading "University of Bristol Wills Memorial Building"
4322
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 07/07/2025
We have a great time on Saturday at #KeynshamMusicFestival talking about how to be an epidemiologist. Thank you to the festival for inviting us and for all the interesting conversations with the people who visited our stall.
A white gazebo under a tree, with two people in front. Hanging from the gazebo are three pictures with holes cut out for faces so people can take photos with them to 'picture yourself as an epidemiologist'. One picture shows a doctor weighing a baby, another shows a someone analysing health data on a laptop, while the third shows someone standing at a podium briefing policy makers.A man in a grey top and a white sunhat and a woman with a spotty dress and blonde pigtails standing in a white gazebo. The man is standing in front of a map of cholera cases in Victorian London. The woman is holding a photo stand in of a painting of someone behind a podium doing a Covid policy briefing.A man points to a map of cholera cases in Victorian London, mounted on a wooden board. This is a game called 'Pin the pump on the map', where visitors put a magnet where they think the contaminated pump is.
010
Reposted by MRC Integrative Epidemiology Unit
hannahjjones.bsky.social @hannahjjones.bsky.social · 06/07/2025
It was absolutely amazing being a part of @merthyrscience.bsky.social yesterday representing @uob-ieu.bsky.social. Had some fantastic discussions on mental health research. Thank you to all involved!!!
131
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 24/06/2025
The role of ‘good’ fats in addressing inflammation is more complex than first thought. Omega-3 fatty acids, popularly believed to reduce inflammation in the body, appear to increase certain inflammatory markers. www.bristol.ac.uk/news/2025/ju...
bristol.ac.uk
‘Good’ fats and inflammation: more complex than first thought
Omega-3 fatty acids, popularly believed to reduce inflammation in the body, appear to increase certain inflammatory markers, researchers have found.
000
Reposted by MRC Integrative Epidemiology Unit
Chloe Slaney @chloeslaney.bsky.social · 10/06/2025
Commentary by @mendelrandom.bsky.social and me on paper suggesting highly prevalent East Asian #ALDH2 null variant may magnify adverse effects of maternal alcohol use during pregnancy on child development. ▶️ onlinelibrary.wiley.com/doi/10.1111/... @uob-ieu.bsky.social @bristoluni.bsky.social
174
Reposted by MRC Integrative Epidemiology Unit
Lavinia Paternoster @lpaternoster.bsky.social · 04/06/2025
New research on genetics of eczema - found interaction between IL7R locus and dog exposure. Not sufficient evidence to suggest getting a dog, but important insight into how one particular mechanism might be influenced by the environment onlinelibrary.wiley.com/doi/10.1111/... @uob-ieu.bsky.social
onlinelibrary.wiley.com
Gene–Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies
Atopic eczema is a complex trait resulting from multiple genetic and environmental factors. This study investigated evidence for interaction between 24 established eczema genetic risk variants and 18...
121
Reposted by MRC Integrative Epidemiology Unit
Éimear M. Foley @eimearfoley.bsky.social · 09/06/2025
Looking forward to this! If you're attending #PNIRS2025 be sure to come to our session (Symposia 4) on Wednesday morning and say hello 👋 @ymilaneschi.bsky.social @dpmoriarity.bsky.social @uob-ieu.bsky.social
097
Reposted by MRC Integrative Epidemiology Unit
Gemma Sharp @gemmasharp.bsky.social · 22/05/2025
Our study is in the news: Heavy and painful periods are linked to missing school and lower GCSE results - something that anyone who menstruates could probably already tell you, but that is largely not discussed or ignored. Well done to Gemma Sawyer @uob-ieu.bsky.social who did all the hard work
064
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 14/05/2025
Next Thursday we'll be part of a Pint of Science event in Bristol on cancer innovations. Come along and hear Naomi Cornish discussing "The Clot Thickens: Cancer's Sticky Accomplice" as well as learning about other interesting research. pintofscience.co.uk/event/cancer...
pintofscience.co.uk
Cancer Innovations
Come and listen to the newest innovations in cancer treatments, from RNA splicing to combination therapy, and a peak to the future of personalised medicine…
000
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 07/05/2025
Depression and other mental health conditions linked with immune response, finds new research from IEU. Read more: www.bristol.ac.uk/news/2025/ap...
bristol.ac.uk
Depression and other mental health conditions linked with immune response, study finds
Depression, schizophrenia and other mental health conditions affect 1 in 4 people in their lifetime, but mechanisms underlying these conditions are poorly understood. New research led by researchers a...
000
MRC Integrative Epidemiology Unit @uob-ieu.bsky.social · 07/05/2025
Young men growing up around parents who are physically violent to each other are 43% more likely to carry out violence or abuse in their own relationships - read about this new research from IEU and @capcbristol.bsky.social www.bristol.ac.uk/news/2025/ma...
bristol.ac.uk
Breaking the cycle: supporting young boys in violent homes could prevent relationship violence, study suggests
Young men growing up around parents who are physically violent to each other are 43% more likely to carry out violence or abuse in their own relationships, new University of Bristol research has found...
022
Reposted by MRC Integrative Epidemiology Unit
Centre for Academic Primary Care (CAPC), Bristol @capcbristol.bsky.social · 02/05/2025
The Medical Research Council (MRC) funded study used Children of the 90s data and was led by Dr Annie Herbert @uob-ieu.bsky.social @capcbristol.bsky.social and published in @lancetrh-europe.bsky.social. Read the full paper: www.thelancet.com/journals/lan...
thelancet.com
The impact of parental intimate partner violence and abuse (IPVA) on young adult relationships: a UK general population cohort study
Interventions supporting young boys exposed to maternal physical IPVA could reduce risks of them using violence or abuse in their relationships. Services supporting families experiencing IPVA should c...
111