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Udai Banerji

@udaibanerji.bsky.social
67 followers 19 following 28 posts

Clinician Scientist, passionate translational medicine and drug discovery in oncology and beyond...

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Udai Banerji @udaibanerji.bsky.social · 06/07/2026
Congratulations to Fisher Lab @ucl.ac.uk on predicting combinations of anticancer drugs, was privileged to be part of the consortium. Executable models offer insights that black box models do not. pubmed.ncbi.nlm.nih.gov/42341181/ @icr.ac.uk @crukconvergence.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 09/05/2026
Research can be all consuming, sometimes you have to stop and look around.....
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Udai Banerji @udaibanerji.bsky.social · 02/05/2026
Proximity induced degradation has only just begun!
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Udai Banerji @udaibanerji.bsky.social · 30/04/2026
The intersection of the PI3K/AKT pathway and immunotherapy. ICECAP study led by Prof Juanita Lopez. pubmed.ncbi.nlm.nih.gov/42043781/ @icr.ac.uk @icrdduiit.bsky.social @icr-ctsu.bsky.social @royalmarsden.org @crukconvergence.bsky.social @ecmc-uk.bsky.social @nihr.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 22/04/2026
At #AACR26. Leveraging cancer stroma to deliver anticancer drugs. Fibroblast co-culture experiments in PDAC and sarcoma cell lines to study the role of AVA6000 a FAP activated doxorubicin prodrug as a single agent and in combination. @icr.ac.uk @crukconvergence.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 21/04/2026
At #AACR26 Poster 6457.CD137 agonist. Exciting responses in breast cancer and high spec pharmacodynamic imaging showing decreasing metabolism (FDG-PET) but increasing lymphocytic infiltration (CD8 PET). @icr.ac.uk @royalmarsden.org @crukconvergence.bsky.social @ecmc-uk.bsky.social @nihr.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 20/04/2026
At ##AACR26 , great to see the Cancer Therapeutics podium filled by ex Drug Development Unit fellows who are now Profs all across the world! @icr.ac.uk @royalmarsden.org . 👏👏👏
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Udai Banerji @udaibanerji.bsky.social · 24/03/2026
Its a honour to be appointed as a NIHR Senior Investigator. The NIHR has kept research at the forefront of the NHS and allows us to perform patient centric, scientifically robust research. @icr.ac.uk @royalmarsden.org @nihr.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 27/02/2026
Seville (bitter) oranges some times used for marmalade or juice but not usually edible as an oranges contain furanocumarins, CYP3A4 inhibitors that increase levels of drugs metabolised by CYP3A4.
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Udai Banerji @udaibanerji.bsky.social · 13/11/2025
Fuelling the qest for the next generation of clinician scientists. Great opportunity!
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Udai Banerji @udaibanerji.bsky.social · 01/11/2025
PhD convocation ceremony at @icr.ac.uk with DrDr Alvaro Graces. His thesis entitled Clonal Dynamics and evolutionary pathways in high grade serous ovarian cancer under therapeutic pressure siggests our current use of chemotherapy can be better optimised. @trevorgraham.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 29/08/2025
Interesting insights into phase I trial recruitment in oncology and health care utilization using data extracted from unstructured text in health care records. pubmed.ncbi.nlm.nih.gov/40855012/ @icr.ac.uk @royalmarsden.org @ecmc-uk.bsky.social @crukconvergence.bsky.social @nihr.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 14/07/2025
Organoid culture is prohibitively expensive. Solution to Harvest Organoids Efficiently (SHOE) allows rapid and inexpensive harvesting of organoids. Please use in your research labs and cite. pubmed.ncbi.nlm.nih.gov/40641211/ @icr.ac.uk @royalmarsden.org @crukconvergence.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 08/07/2025
Antibody-drug-conjugate toxicity is real and poorly understood. Looking for trends in association with antibody/linker/payloads. pubmed.ncbi.nlm.nih.gov/40611310/ @icr.ac.uk @royalmarsden.org @ecmc-uk.bsky.social @crukconvergence.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 27/06/2025
Published today @natmed.nature.com www.nature.com/articles/s41... Thank you to all patients, families and research staff. @icr.ac.uk @icrdduiit.bsky.social‬ ‪@icr-ctsu.bsky.social @royalmarsden.org @ecmc-uk.bsky.social‬ @nihr.bsky.social @crukconvergence.bsky.social @cancerresearchuk.org ‪
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Udai Banerji @udaibanerji.bsky.social · 27/06/2025
Published today in @natmed.nature.com www.nature.com/articles/s41... combination of avutometinib and defactinib in LGSOC. @icr.ac.uk‬ @icrdduiit.bsky.social‬ @icr-ctsu.bsky.social @royalmarsden.org @ecmc-uk.bsky.social @nihr.bsky.social‬ ‪@crukconvergence.bsky.social @cancerresearchuk.org ‪
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Udai Banerji @udaibanerji.bsky.social · 19/06/2025
#MCCR2025. Methods in clinical cancer research workshop hits its 25 year birthday! Fabulous opportunity to train young oncologists to develop research protocols. Especially proud to have been a trainee over 20 years ago and having served as faculty. @ESMO @EORTC @theaacr.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 07/05/2025
Sharing good practice to run complex radio-immuno conjugate trials in the UK to accelerate drug development and improve outcomes of cancer patients. @ecmc.bsky.social @icr.ac.uk @icrdduiit.bsky.social @nihr.bsky.social @cruk.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 30/04/2025
Professor Paul Workman, fellow of AACR, talking on the urgency in developing chemical probes to fight cancer. #AACR2025 @icr.ac.uk
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Udai Banerji @udaibanerji.bsky.social · 30/04/2025
End of a long day at AACR. Presented using patient derived organoids to understand and refine mechanisms of synergy of avutometinib and defactinb combination in low grade ovarian, an area of unmet need. @icr.ac.uk @crukconvergence.bsky.social @nihr.bsky.social @ecmc-uk.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 26/04/2025
Masterclass in next generation ADCs! ED11 #AACR2025 worth watching online if you missed it.
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Udai Banerji @udaibanerji.bsky.social · 26/04/2025
Only at #AACR 2025, Love the commitment!!!
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Udai Banerji @udaibanerji.bsky.social · 26/04/2025
#AACR2025 has begun. Educational sessions on plasticity/drug resistance and models of cancer evolution. Feel the buzz! @icr.ac.uk @cancerresearchuk.org @nihr.bsky.social
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Udai Banerji @udaibanerji.bsky.social · 26/02/2025
Happy retirement to my wife Jane, joined nurse training 42 years ago, worked across several NHS trusts and Australian public hospitals on clinical trials of carboplatin, VP16 (etoposide), GCSF, ondansetron and CHART RT in clinic. Worked in tral management @icr since 2005. Time to put up your feet!
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Udai Banerji @udaibanerji.bsky.social · 24/01/2025
www.icr.ac.uk/about-us/icr... Blog about projects @icrlondon.bsky.social in ovarian cancer. Its only the tip of the iceberg, there are many exciting projects too early to talk about! Blessed to be a small cog in the big wheel of progress in cancer research at my institution and beyond…
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Udai Banerji @udaibanerji.bsky.social · 11/01/2025
Unfolded protein response meets AR transcription. We need to think out the box to tackle known oncogenic drivers. Great piece of work from my colleague @AdamSharpMedOnc out this week aacrjournals.org/clincancerre... @icrlondon.bsky.social @theaacr.bsky.social
aacrjournals.org
NXP800 activates the unfolded protein response, altering AR and E2F function to impact castration-resistant prostate cancer growth
Abstract. Purpose: Advanced prostate cancer (PCa) is invariably fatal with the androgen receptor (AR) being a major therapeutic target. AR signaling inhibitors have improved overall survival for men w...
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Udai Banerji @udaibanerji.bsky.social · 08/01/2025
Very interesting personalized m-RNA cancer vaccine paper in nature medicine www.nature.com/articles/s41... published this week establishing proof concept of the technology. Trial was led by my colleague Juantia Lopez and our unit was involved as part of an international clinical trial.
nature.com
Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial - Nature Medicine
In this phase 1 trial, patients with locally advanced or metastatic solid tumors were treated with the individualized mRNA neoantigen-specific immunotherapy (iNeST) autogene cevumeran alone or in comb...
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