iiinova — where your digital self keeps evolving

Reposted by Andy Truman PhD

Anna Leder @annaleder.bsky.social · 21/09/2026

A huge thank you to my co-first authors Raju and @masgu.bsky.social, our collaborators Nadinath Nillegoda, @trumanlab.bsky.social, @paolodelosrios.bsky.social, @chercheurjuteux.com, @hillerlab.bsky.social and everyone else involved!

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Reposted by Andy Truman PhD

Mathieu M.J.E. Rebeaud @chercheurjuteux.com · 17/09/2026

A conserved tyrosine motif encodes a structural vulnerability controlling stability and activity across J-domain proteins This interesting story, which involved several labs and some ideas of my own, has finally been released. www.nature.com/articles/s42...

nature.com

A conserved tyrosine motif encodes a structural vulnerability controlling stability and activity across J-domain proteins - Communications Biology

NMR spectroscopy and functional assays define a conserved tyrosine motif outside the canonical J-domain core of J-domain proteins. The motif stabilizes the fold, and its phosphomimetic perturbation dr...

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Andy Truman PhD @trumanlab.bsky.social · 27/04/2026

Honored and humbled to have received the UNC Charlotte Klein College of Science Excellence in Research Award (Advanced Scholar) for our work on Proteostasis and the Hsp70 chaperone code 🔥

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Reposted by Andy Truman PhD

Mathieu M.J.E. Rebeaud @chercheurjuteux.com · 15/04/2026

Voilà enfin le papier dont je vous parlais depuis un petit temps. Hsp70 diversification and repurposing across the tree of life: Lessons from the evolutionary and mechanistic trajectory of the Hsp70–Hsp110 chaperone system febs.onlinelibrary.wiley.com/doi/10.1111/...

febs.onlinelibrary.wiley.com

FEBS Press

Evolutionary and mechanistic divergence in the Hsp70–Hsp110 chaperone system. Prokaryotic Hsp70s probably diversified into multiple orthologues that cooperated with co-chaperones such as JDPs and NEF...

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Andy Truman PhD @trumanlab.bsky.social · 18/09/2025

Colleague Shan Yan doing a great job highlighting our Genome research at the NC Biotech Summit at the newly opened Pearl campus in Charlotte!

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Andy Truman PhD @trumanlab.bsky.social · 13/09/2025

Had a wonderful time visiting Marquette University Biological Sciences to share our recent work on the Hsp70 Chaperone Code! Thanks to Emily Sontag for inviting me! Such a beautiful campus and loved talking with the students and faculty about the exciting research going on 🔥🔥🔥#hsp70

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Reposted by Andy Truman PhD

American Society for Biochemistry and Molecular Biology @asbmb.bsky.social · 10/09/2025

This study, led by Megan Mitchem & Ashley Choi at the Truman Lab (@trumanlab.bsky.social), provides a resource for dissecting the functional landscape of Cdc37 post-translational regulation & highlights new regulatory sites w/potential relevance to chaperone-kinase network dysregulation in disease.

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Andy Truman PhD @trumanlab.bsky.social · 20/08/2025

Friday was the 10th anniversary of setting up my lab! My amazing team hosted a party-the showstopper was the video they made that contained messages from all my previous students, mentors and collaborators!Finished the day by failing Beat the bomb in Charlotte!

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Andy Truman PhD @trumanlab.bsky.social · 06/08/2025

@ronbeavis.bsky.social Hi Ron, I teach a graduate course on cell signaling and each year do a couple of classes on PTMs. I love showing the students how to use the gpmdb for their studies but can’t access it anymore from the US. Do you offer paid access/educational discount for those in the US?

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Andy Truman PhD @trumanlab.bsky.social · 01/07/2025

Excited to begin my new role as Associate Chair for Research in the Department of Biological Sciences at UNC Charlotte 🔥🔥

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Andy Truman PhD @trumanlab.bsky.social · 13/06/2025

Great time celebrating the achievements of the lab at Fahrenheit restaurant-graduations, proposal defenses, papers and grants! So grateful for the hard work and energy my team bring!

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Reposted by Andy Truman PhD

Andy Truman PhD @trumanlab.bsky.social · 08/09/2023

A really important skill for trainees to learn is to be a “closer” of a project-that is to take it over the finish line for publication. This means doing the experiments, getting the figures/text ready for submission and being prepared to do review corrections 😀

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Andy Truman PhD @trumanlab.bsky.social · 05/06/2025

Classic NIH shenanigans-R03 scores: A0: ND A1: 26 (need 25 to be funded) Revised A0: 40 😭

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Reposted by Andy Truman PhD

Mathieu M.J.E. Rebeaud @chercheurjuteux.com · 03/06/2025

On adaptation to a mesophilic environment and the chaperone network in Archaea Hopla il est là et je ferais une petite explication de ce que j'ai cherché à comprendre dedans. Mais ça parle de chaperonnes et d'archées et de relations entre évolution et HSP70. www.biorxiv.org/content/10.1...

biorxiv.org

On adaptation to a mesophilic environment and the chaperone network in Archaea

A prevailing hypothesis for the emergence of life on Earth holds that it might have originated in hydrothermal vents, where the environmental conditions, although physically and chemically extreme (ac...

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Andy Truman PhD @trumanlab.bsky.social · 12/05/2025

Grateful to have been awarded the first UNC Charlotte Klein College of Science award for Research and Scholarship (KNOBEL) 🔥🔥🔥

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Andy Truman PhD @trumanlab.bsky.social · 24/04/2025

Another Hsp70-Hsp90 complex spotted in the wild 🔥🔥🔥

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Andy Truman PhD @trumanlab.bsky.social · 17/04/2025

Proud of undergraduate students Shreya Patel and Erica Flores on doing a great job presenting their work at the University of North Carolina at Charlotte Undergraduate Research Symposium! Incredible findings on the Hsp70 and BiP PTM code!

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Andy Truman PhD @trumanlab.bsky.social · 17/04/2025

I started using Merlin about a month ago and my kids aged 7 and 11 love it! We have found so many cool birds in Charlotte :)

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Andy Truman PhD @trumanlab.bsky.social · 01/04/2025

You are doing that on a daily basis?

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Andy Truman PhD @trumanlab.bsky.social · 31/03/2025

My ioniq 5 has a range of 320 miles. Most people don’t need more than this in one go.

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Reposted by Andy Truman PhD

Saccharomyces Genome Database @yeastgenome.bsky.social · 20/03/2025

The Pacific Northwest Yeast Club is holding their annual meeting on June 20th, 2025 in beautiful Vancouver, Canada! There are only 100 spots and registration is open now: www.pnwyc.net

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Reposted by Andy Truman PhD

Yeast Journal @yeast-journal.bsky.social · 10/02/2025

Hi everybody! The Yeast journal is finally on Bluesky! Follow us to keep updated on the latest research articles, reviews and special issues on #Yeast biology and more! 🙂

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Andy Truman PhD @trumanlab.bsky.social · 27/03/2025

The celebration of UNC Charlotte reaching R1 status was such a positive and inspiring event! Go Niners 🔥🔥🔥

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Andy Truman PhD @trumanlab.bsky.social · 06/03/2025

Our inaugural Rising Stars in Proteostasis seminar was a roaring success! Thanks to Dr. Ian Guldner for visiting from Stanford University and giving an amazing talk on the decline of proteostasis in aging 🔥🔥🔥 #proteostasis #charlotte

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Andy Truman PhD @trumanlab.bsky.social · 05/03/2025

His got mixed up between transgender and transgenic

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Andy Truman PhD @trumanlab.bsky.social · 05/03/2025

Access to the GPM database removed for US researchers 😬

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Andy Truman PhD @trumanlab.bsky.social · 02/03/2025

I can no longer access pubmed or eracommons WTH is going on????

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Reposted by Andy Truman PhD

Mark Peifer (He, him) @peiferlabunc.bsky.social · 01/03/2025

In a remarkable new paper, Qureshi and Duss use multi-colour single-molecule fluorescence microscopy to directly and simultaneously track transcription, translation & coupling 3/n www.nature.com/articles/s41...

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Reposted by Andy Truman PhD

Elaine Luo @oceanmicrobes.bsky.social · 20/02/2025

Hi everyone! New here 😄 excited to connect and learn about/share cool research in aquatic microbial ecology, or just science in general! Here's our lab photo to kick-start another year! #newPI

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Andy Truman PhD @trumanlab.bsky.social · 18/01/2025

Incredible as always-Rick Morimoto gives the final talk of the day at the Midwest Stress Response and Molecular Chaperone Meeting 🔥

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Andy Truman PhD @trumanlab.bsky.social · 18/01/2025

This is a major meeting for the molecular chaperone field

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Andy Truman PhD @trumanlab.bsky.social · 18/01/2025

So excited to be back in Chicago for the Midwest Stress Meeting!

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Andy Truman PhD @trumanlab.bsky.social · 16/12/2024

We’ve had a great response so far! Please forward to any researchers that may be interested! 😀

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