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Thomas R. Cox

@trcox.matrixandmetastasis.com
2.5K followers 441 following 36 posts

Professor & Head of the Matrix & Metastasis Lab at the Garvan Institute of Medical Research & UNSW Sydney Gadigal Country 🇦🇺 🏳️‍🌈 🔬Pancreatic / Lung / Breast / Bowel Cancer & all things extracellular matrix 🧫 → linktr.ee/thomasrcox ←

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Reposted by Thomas R. Cox
Garvan Institute @garvaninstitute.bsky.social · 22/09/2026
Applications for our Summer Scholarships Program are open. We welcome applications from students who demonstrate initiative, original thinking and a genuine passion for discovery. 🔗Learn more or apply here: ow.ly/PCur50ZPYkf #SummerScholarships #MedicalResearch #CareerDevelopment
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Garvan Institute @garvaninstitute.bsky.social · 09/08/2026
The finishing touches are going up 👀 Tomorrow, Art of Discovery opens its doors – a free, immersive exhibition where our researchers turn cancer, genomics and immunology into illuminated art. 🔗 Plan your visit: ow.ly/X4Gi50ZxkH2 #ArtOfDiscovery #ImmersiveExhibition #ScienceAndArt
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Garvan Institute @garvaninstitute.bsky.social · 08/07/2026
Aggressive lung cancer uses our body’s own structural scaffolding to spread. With support from The Global Lung Cancer Impact Challenge, Dr Amelia Parker is developing new antibody therapies to block cancer’s support network. 🔬Read more: ow.ly/rSWw50ZlprF #LungCancer
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Metastasis Research Society @metastasisresearch.bsky.social · 28/06/2026
Excited to be kicking things off today for the 21st biennial Congress of the MRS. Going to be a fantastic couple of days ahead #MRS2026 #metastasis
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Metastasis Research Society @metastasisresearch.bsky.social · 30/06/2026
Day 1 of the MRS Biennial Congress brought together metastasis researchers from across the globe, trainees and PIs alike. Grateful for a moment to capture this incredible scientific community. #MRS2026 #metastasis #TME
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Julie S. Di Martino, PhD. @juliesdimartino.bsky.social · 22/06/2026
I’m thrilled and truly honored to share that I have received a @susangkomen.bsky.social Career Catalyst Research grant to support my lab’s work on breast cancer dormancy. I’m deeply grateful to my mentors and patient advocate for their continuous support in helping me reach this milestone.🎗️
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Garvan Institute @garvaninstitute.bsky.social · 27/03/2026
Just published: Garvan researchers have mapped the world’s most detailed cellular ‘atlas’ of early-stage prostate cancer. Prof Alexander Swarbrick’s team showed that many entirely "healthy-looking" cells already harbour cancer-related DNA changes. ow.ly/fFAw50Yzu6O
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Garvan Institute @garvaninstitute.bsky.social · 27/03/2026
City2Surf entries are now open! Support vital medical research by taking part with #GoGarvan. Learn more on our website: ow.ly/wCLb50YzwpH #City2Surf #SydneyRunning #RunForResearch #CharityRun #RunSydney #ActiveForACause #SupportResearch #SydneyEvents #MedicalResearc #City2Surf #2026
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Metastasis Research Society @metastasisresearch.bsky.social · 28/02/2026
EXCITING NEWS! Registration and abstract submission for the 21st Biennial Congress of the MRS is now OPEN! Find all the information here: metastasis-research.org/2024/06/26/m...
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Reposted by Thomas R. Cox
Garvan Institute @garvaninstitute.bsky.social · 29/01/2026
In this episode, Dr Ankur Sharma delves into the critical insight that cancer is not just a rogue cell – it’s an entire ecosystem – and that ecosystem is the key to unlocking a new class of cures. Listen here: ow.ly/NWGN50Y44tv
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Reposted by Thomas R. Cox
Metastasis Research Society @metastasisresearch.bsky.social · 22/01/2026
Are you as excited as we are for the 2026 MRS Biennial Meeting? As we get closer, we’ll be highlighting speakers each week, starting today!
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William Hill @drwilliamhill.bsky.social · 22/01/2026
Incredible work demonstrating a functional role for malignant cell states in preclinical lung cancer models www.nature.com/articles/s41...
nature.com
Critical role for a high-plasticity cell state in lung cancer - Nature
The high-plasticity cell state (HPCS) is a critical hub that enables reciprocal transitions between cancer cell states, and targeting the HPCS may suppress cancer progression and eradicate treatment r...
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Reposted by Thomas R. Cox
Garvan Institute @garvaninstitute.bsky.social · 22/01/2026
Exciting news: Garvan’s Prof Marina Pajic has been awarded MRFF funding to lead a team undertaking two trials testing new approaches for pancreatic cancer. Read more: ow.ly/t4eW50Y0Z5F
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Garvan Institute @garvaninstitute.bsky.social · 16/01/2026
An international team, co-led by Garvan's Prof Stuart Tangye, has discovered that the protein CBL is crucial for B cell development, shedding light on immune function and why some people are more prone to infections. Published today in Nature Immunology: ow.ly/gk4z50XX0Y7
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Johanna Joyce @johannajoyce.bsky.social · 17/12/2025
Very pleased to share our new review "The Evolving Landscape of Brain Metastasis" in @cp-trendscancer.bsky.social 🧠🔬🧪 Grateful to an outstanding team of co-authors, all pioneers in the #brain #metastasis field and to @valientelab.bsky.social for co-leading this 🙏🏻 Link: www.cell.com/trends/cance...
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Thomas R. Cox @trcox.matrixandmetastasis.com · 10/12/2025
We're looking for a Research Assistant / Senior Research Assistant to join our team. If you're interested in studying the extracellular matrix and tumour microenvironment in cancer, then get in touch. Applications will be reviewed on a rolling basis. garvan.wd3.myworkdayjobs.com/garvan_insti...
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Thomas R. Cox @trcox.matrixandmetastasis.com · 04/12/2025
Enormous thank you to the Australian Cancer Research Foundation for awarding us a $2.5m grant to launch the ACRF MATRIX Centre – a dedicated national centre for visualising & decoding the tumour microenvironment & its impact on therapy resistance & metastasis. www.garvan.org.au/news-resourc...
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Reposted by Thomas R. Cox
Metastasis Research Society @metastasisresearch.bsky.social · 20/11/2025
Still buzzing from the fantastic ECLC virtual meeting! Thank you to all speakers and attendees for the compelling talks and discussions on metastasis research. On today, World Pancreatic Cancer Day, we honor every patient and researcher. Share your favorite paper from 2025. Starting here:
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Metastasis Research Society @metastasisresearch.bsky.social · 04/11/2025
The MRS is excited to announce the awardees for the 2026 MRS Awards. Each will be presenting at the 2026 Biennial Congress in Salt Lake City, Utah, June 28 - July 1, 2026, don't miss it! 🎉Congratulations to all of our awardees! 🎉
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Metastasis Research Society @metastasisresearch.bsky.social · 03/11/2025
🚀 Two weeks to go! The ECR Meeting brings together early-career scientists driving the next wave of metastasis research. ⚡ Don’t miss: 💡 Inspiring talks from rising leaders 💬 Community-led discussions 🌍 A global metastasis community 🗓️ Register by Nov 18 ➜ bit.ly/4qyxE0o Program ➜ bit.ly/4qtpVR9
metastasis-research.org
2nd MRS Early Career Research Virtual Meeting | Metastasis Research
The 2025 MRS Early Career Research Virtual Meeting is a two day meeting aimed at engaging trainees and early career researchers from around the world and highlighting recent advances in metastasis research through keynote presentations, invited talks, panel discussions, and selected talks from abstracts. The meeting is organized and hosted by the Early Career Leadership Council (ECLC) of the MRS. Abstracts are being accepted for consideration for oral presentations. Abstract submission is open to graduate students, postdoctoral fellows, medical students, residents, clinical fellows, and researchers within 3 years of starting their own independent research group. Registration for this meeting is free for MRS Members!
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Metastasis Research Society @metastasisresearch.bsky.social · 27/10/2025
🚀 The program is LIVE! Our ECR Virtual Meeting brings together trainees & junior PIs pushing the frontiers of metastasis research. 💡 Inspiring talks 🤝 Community-led discussion sessions 🌍 A global Metastasis Research Society Program ➜ bit.ly/4qtpVR9 Register by Nov 18 ➜ bit.ly/4qyxE0o
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Metastasis Research Society @metastasisresearch.bsky.social · 24/10/2025
🎗️ October is #BreastCancerAwarenessMonth! 💗The MRS honors survivors and researchers, including our MRS president, Dr. Alana Welm, who recently received Innovator of the Year award for advancing & sharing patient-derived breast cancer models enabling precision medicine. bit.ly/493BMiL
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Anna Obenauf @obenaufa.bsky.social · 13/10/2025
Excited to present at the @metastasisresearch.bsky.social webinar soon. Registration is free!
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Mac4Me @mac4me.bsky.social · 13/10/2025
Metastatic disease affects 20-30% of early breast cancer patients. This is the frontier where we need to focus.🎯 Mac4Me’s goal is to help transform metastatic breast cancer from a typically terminal condition into a chronic or potentially curable one. #MetastaticBreastCancerAwarenessDay
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Cancer Research UK Manchester Institute @cruk-mi.bsky.social · 08/10/2025
Interested in establishing your own research group? Our support package for new Group Leaders includes: 🥼2 #Postdocs, a technician & 2 PhD students + lab costs 🔬Full access to core facilities 🧪Access to the MCRC #Biobank ✔️Mentorship, #grant advice & more www.cruk.manchester.ac.uk/career/new-g...
Graphic has a blue-tone photograph of the Paterson Building on the right-hand side, with a dark blue background and white text on the left

Text says:

We Are Recruiting New Group Leaders
Join us in Manchester / Develop bold, innovative, & high-impact research programmes
Salary £58,000 – £65,000 (dependent upon experience/clinical work)
Job ID MI/25/54
Apply by 2nd November 2025
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Reposted by Thomas R. Cox
Shona Ritchie @shonaritchie.bsky.social · 07/10/2025
Had a fantastic time at @myueg.bsky.social week in Berlin, sharing science and meeting new colleagues/pals! Huge thanks to @metastasisresearch.bsky.social for making it possible for me to attend and share our research
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Metastasis Research Society @metastasisresearch.bsky.social · 19/09/2025
Attending a meeting? Early career MRS members can apply for a bursary! metastasis-research.org/for-research... 🚨Next bursary deadline is:October 1! 🚨 🎉 Congratulations again to our latest MRS Travel Bursary winners! 🌍 Shona Ritchie (Australia) 🇺🇸 Abby Jackson (USA) 🇮🇱 Avishai Maliah (Israel)
metastasis-research.org
MRS Meeting Bursaries | Metastasis Research
The Metastasis Research Society is pleased to announce the availability of up to 10 Early Career Researcher (ECR) travel scholarships annually. These scholarships aim to support young investigators in presenting their metastasis research at national and international conferences.
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EACR - European Association for Cancer Research @helloeacr.bsky.social · 24/09/2025
As our Goodbye Flat Biology conference in Essen coincides with #WorldCancerResearchDay, what better way to mark the occasion than with a group photo? #WCRD @wcrd24sept.bsky.social
Group photo of a conference hall filled with participants posing in front of a World Cancer Research Day slide
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Metastasis Research Society @metastasisresearch.bsky.social · 11/09/2025
Don't miss our next webinar by Zoi Diamantopoulou on "Timing the perfect strike: Using circadian rhythms to target metastasis" - September 22, 2025 - more details and register here: metastasis-research.org/2025/09/11/z...
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Aguirre-Ghiso Lab @jaguirreghisolab.bsky.social · 04/09/2025
Pioneering trial targeting dormant residual cancer cells by L. Chodosh, A. DeMichele et al., @penncancer.bsky.social Proof-of-concept that targeting dormant RTCs in breast cancer survivors depletes MRD. NCT03032406. Congratulations for this work! www.nature.com/articles/s41...
nature.com
Targeting dormant tumor cells to prevent recurrent breast cancer: a randomized phase 2 trial - Nature Medicine
A combination of mouse model data and data from a randomized phase 2 trial in patients with breast cancer in remission demonstrates feasibility, safety and a reduction in residual tumor cells followin...
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Matthia Karreman @matthiakarreman.bsky.social · 04/09/2025
How do #metastases survive (and thrive!) in the #brain microenvironment? In our review, now online @cp-neuron.bsky.social, we discuss the recent findings on #cancerneuroscience of #brainmetastases: Learn all about how #cancer cells adapt to, and communicate with, this unique environment 🧠
authors.elsevier.com
ScienceDirect.com | Science, health and medical journals, full text articles and books.
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Metastasis Research Society @metastasisresearch.bsky.social · 25/08/2025
🚨Excited for the 2nd MRS Early Career Research Virtual Meeting on Nov 18-19, 2025! Trainees & Junior Faculty (within 3 years of starting your lab), share your work! Abstract Deadline: Sept 12, 2025. Submit here: bit.ly/47KLyp2 ❗Free registration for MRS Members! #MRS #Research #EarlyCareer
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RedPen/BlackPen @redpenblackpen.bsky.social · 08/08/2025
Really just had something like this feeling this afternoon. It’s the high that keeps you coming back for more
Cartoon of a scientist peering through a microscope saying "Whoaah!!!". Title says "The best part of Science is knowing, for a moment, something that nobody else in the world knows."
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Denis Wirtz @deniswirtz.bsky.social · 08/08/2025
The updated version of the database of PhD fellowships produced and maintained by my team can be downloaded by anyone here: research.jhu.edu/rdt/funding-... For each of the 187 fellowships, you will find a short description, deadline, $ amount, link, etc. Good luck!
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Metastasis Research Society @metastasisresearch.bsky.social · 06/08/2025
Calling all ECRs in cancer and metastasis research. Don't forget to register for the upcoming ECR Virtual Symposium in November (FREE for MRS members). More details here metastasis-research.org/2025/08/06/2...
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Mathew Kiang @mathewkiang.com · 25/06/2025
Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages. ki.se/en/about-ki/...
ki.se
Call for 20 Assistant Professor positions
Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...
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Jon Humphries @jdhl18.bsky.social · 27/06/2025
Evolutionary paths towards metastasis www.nature.com/articles/s41...
nature.com
Evolutionary paths towards metastasis - Nature Reviews Cancer
In this Perspective, Kamila Naxerova discusses how genetic analyses of primary tumours and matched metastases can distinguish between competing metastasis evolution models, arguing that further insigh...
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Johanna Joyce @johannajoyce.bsky.social · 27/06/2025
🧠 Neuro-immunology is reshaping how we understand the brain - across many diseases, including #cancer In this research highlight 🧪🔬 we discuss a new study in #Nature by Remsik, Boire et al showing how IFNγ-activated immune cells in the CNS, incl DCs, help constrain leptomeningeal #metastasis
nature.com
CNS gatekeepers: IFNγ-activated dendritic cells control leptomeningeal metastasis - Cell Research
Cell Research - CNS gatekeepers: IFNγ-activated dendritic cells control leptomeningeal metastasis
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Nature Portfolio @natureportfolio.nature.com · 28/06/2025
Nature reports on how scientists are working to decipher the precise mechanisms that connect the brain to processes associated with ageing. #medsky 🧪
go.nature.com
How your brain controls ageing — and why zombie cells could be key
Research is revealing the cellular mechanisms that link mental well-being and longevity.
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Metastasis Research Society @metastasisresearch.bsky.social · 23/06/2025
Register for our next ECLC webinar by Marco Montagner, PhD on Understanding the determinants of the invisible phase of metastasis - June 26th, 2025 - USA: 11:00 AM EDT | Europe: 17:00 PM CEST | Australia: 01:00 AM AEST - tinyurl.com/ujer8yw8
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Guillaume Jacquemet @guijacquemet.bsky.social · 23/06/2025
Are you looking for a postdoc? I will be looking for 2-4 people after the summer to join the lab !! Do not hesitate to reach out and disseminate !!
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Metastasis Research Society @metastasisresearch.bsky.social · 17/06/2025
1/Meet the MRS ECLC Chairs! Dr. Thomas Cox @trcox.matrixandmetastasis.com is a Professor at the @garvaninstitute.bsky.social focussing on the Extracellular Matrix and Fibrosis in Cancer. We interviewed Dr. Cox about his role as a founding member of the MRS Early Career Leadership Council 🧵👇
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OzMRS @ozmrs.bsky.social · 13/06/2025
Save the date! OzMRS Symposium 2025 will take place at the University of Wollongong on the 29th and 30th of October. More information coming soon. #Metastasis #CancerResearch
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Thomas R. Cox @trcox.matrixandmetastasis.com · 11/06/2025
New Review on Organ Repair & Fibrosis Repeated organ injuries leads to abnormal ECM remodelling, disrupting tissue structure and function. Nice summary of the ECM's role in persistent fibrosis, organ-specific healing mechanisms, and anti-fibrotic strategies. www.nature.com/articles/s44...
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Thomas R. Cox @trcox.matrixandmetastasis.com · 04/06/2025
New review paper written by Jess Chitty in the team just out in Trends in Cancer (@cp-trendscancer.bsky.social) (OpenAccess) The extracellular matrix in cancer: from understanding to targeting | → www.sciencedirect.com/science/arti... ← |
sciencedirect.com
The extracellular matrix in cancer: from understanding to targeting
Significant advances in matrix biology research have enhanced our understanding of individual matrix components and extracellular matrix (ECM) signall…
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Thomas R. Cox @trcox.matrixandmetastasis.com · 03/06/2025
June 4th = National Cheese Day 🧀 Sounds like a great excuse to eat one’s entire body weight in cheese 🤩 😋
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Metastasis Research Society @metastasisresearch.bsky.social · 03/06/2025
Register for our next ECLC webinar by Marco Montagner, PhD on Understanding the determinants of the invisible phase of metastasis - June 26th, 2025 - USA: 11:00 AM EDT | Europe: 17:00 PM CEST | Australia: 01:00 AM AEST - tinyurl.com/ujer8yw8
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Thomas R. Cox @trcox.matrixandmetastasis.com · 02/06/2025
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells www.nature.com/articles/s41...
nature.com
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells - Nature Cell Biology
Conway et al. show that integrin β1 phosphorylation is regulated through balanced activities of tyrosine kinases, such as Src and Arg, and phosphatases, such as PTP-PEST and Shp2, facilitating invadop...
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Phil Gregory @drphilgregory2.bsky.social · 29/05/2025
My lab at the Center for Cancer Biology (UniSA, Adelaide, Australia) has a fully funded PhD position open to domestic or international students to explore the functions of alternative spliced isoforms in prostate cancer progression. @CCB_Research www.unisa.edu.au/research/deg...
unisa.edu.au
Discovery of alternative splicing pathways that promote lethal castrate resistant prostate cancerminus-thickplus-thickminus-thickplus-thickminus-thickplus-thickminus-thickplus-thickminus-thickplus-thi...
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MBSANZ @mbsanz.bsky.social · 28/05/2025
Join us in Lorne for the 13th International Proteoglycan Meeting & the annual scientific meeting of @mbsanz.bsky.social Meet our Speakers! Over the next few weeks, we will feature each of the fantastic speakers who will join us in Lorne. More information below - mbsanz2025.smalltalkevents.com.au
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