The study also distinguishes between feeling fatigued and becoming progressively less able to maintain performance post-COVID.

Flu arrives to Pacific states; COVID wave seen in US, England, and Europe; Neuro-Long COVID and HHV-7; a 5th Pennsylvania measles death; Plague lab accident in Siberia; and much more.

Health authorities in Siberia’s Irkutsk region have placed nearly 200 people under medical observation after a laboratory worker died from plague, according to media reports and a statement by a regio...

Communications Medicine - Functional antibody responses and protection against symptomatic dengue

Podcast Episode · Quiet Riot · 4 October · 1hr 2min

Experts say now is an ideal time to get a flu shot, before influenza starts spreading widely

Researchers at the Francis Crick Institute, King’s College London and Complutense University of Madrid have shown that γδ T cells use adaptive immune receptors to drive rapid, innate-like responses to...

### What you need to know Altitude illness is a collective term for syndromes that can occur in unacclimatised people who travel to destinations higher than 2500 metres above sea level.1,2,3 Altitud...

As preparedness lags, many regions around the world could be overwhelmed by rising temperatures, climate experts warn.

Senior Downing Street officials reach out to thinktanks and pollsters as they look to test backing for reversing Brexit

Climate change is shaping health in the 21st century. In the past few weeks alone, Nepal has faced unprecedented flash floods, and multiple countries have experienced deadly heatwaves and catastrophic...

3 track album

People with CKDu don’t have the classic risk factors of kidney disease, like hypertension or diabetes.

Follicular regulatory T (Tfr) cells enter the B-cell follicle and germinal center, where they control the magnitude, specificity, and duration of the antibody response. However, the temporal and spatial determinants of Tfr differentiation are incompletely understood. Recent advances in fate-mapping, single-cell transcriptomics, and human tissue analyses have revealed that Tfr cells differentiate progressively through distinct differentiation states, a process directed by follicular helper T cells. Tfr differentiation states have unique transcriptional identities, functional roles, and stabilities revealing intricate feedback loops controlling humoral immunity. Here, we review recent findings on the origins and functions of Tfr cells in mice and humans, how these subsets are intrinsically and extrinsically controlled, and how targeting these pathways may treat human disease.

Changes in guidance and science seem to have little impact on millions of devastated lives. It’s a social crisis playing out behind closed doors, says Guardian columnist George Monbiot

Two that are promising, and one that is difficult to talk about

The bacteria responsible picked up some new genetic material, say experts.

Oropouche virus (OROV), an emerging arbovirus of the genus Orthobunyavirus, has become a growing public health concern following its recent expansion across the Americas and its potential to cause severe clinical outcomes in maternal and child health. Although Oropouche fever has classically been described as an acute self-limited febrile illness, accumulating evidence indicates that OROV is associated with meningitis and fatal infection, as well as evidence of vertical transmission associated...

The AfD is on the path to power. It doesn’t just want to take Germany in a different political direction – it wants to build a new country

Clinician conversations with patients will matter more than ever

Historically, state health departments determine cases and deaths, not the CDC.

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Exploratory analyses examining associations between SARS-CoV-2 infections and newly diagnosed health conditions

Spiritual leaders stress diversity of views within Jewish community and warn against inaction on settler violence Prominent British rabbis have backed Ed Miliband’s sanctions on Israeli settlements, warning that the time for inaction on settler violence must come to an end. The intervention comes after the UK’s chief rabbi, the spiritual leader of mainstream Orthodox Jews in the UK, Sir Ephraim Mirvis, described UK sanctions against illegal Israeli settlements in the occupied Palestinian territories as a “dark day for British Jews” and warned they could embolden people who “use hatred as a weapon against Jews”. Continue reading...