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Tom Golde

@tomgolde.bsky.social
193 followers 304 following 14 posts

biophysics. post-doc @XavierTrepat lab barcelona. currently focused on intermediate filaments and epithelial tissues.

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Reposted by Tom Golde
Wolfram Pönisch @wolframponisch.bsky.social · 18/08/2026
Postdoc in my group at @humantechnopole.bsky.social! We want to answer how single-cell morphodynamics is connected to cell topology & state in cell collectives, using data analysis and theoretical modelling. Please share! careers.humantechnopole.it/job/Postdoc-...
careers.humantechnopole.it
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Tom Golde @tomgolde.bsky.social · 27/07/2026
This is the result of many years as a postdoc in the lab of @xaviertrepat.bsky.social. Simulations were done in Marino Arroyo’s lab by @marcopensalfini.bsky.social. Special thanks to @onenimesa.bsky.social and my collaborators @gcharras.bsky.social, Gerhard Wiche, and @pcusachs.bsky.social
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Tom Golde @tomgolde.bsky.social · 27/07/2026
We finally demonstrate that bundling is a collective process starting in a few initial cells and spreading towards a cluster of cells with a supracellular keratin bundle network.
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Tom Golde @tomgolde.bsky.social · 27/07/2026
The bundle transition is surprisingly slow and dynamics are controlled by keratin-actin interactions. Via computational models, we show that nuclear uncaging releases compressive stress on the nucleus, raising the question if this protects the nucleus or exposes it to more mechanical forces.
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Tom Golde @tomgolde.bsky.social · 27/07/2026
New paper in @natphys.nature.com! We uncovered a stress adapation mechanism where keratin intermediate filaments in stretched epithelia undergo a supracellular bundling transition that uncages the nucleus. www.nature.com/articles/s41... @ibecbarcelona.eu, @upc.edu @qmul.bsky.social
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Tom Golde @tomgolde.bsky.social · 10/04/2026
Coming back from the EMBO workshop "Structure and Function of the Cytoskeleton" in Paris. Happy to report that I won the best poster award for a story about intermediate filaments in a conference full of actin and microtubule people. Many thanks to the organizers for a great conference!
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Tom Golde @tomgolde.bsky.social · 08/04/2026
Spending the week at the EMBO workshop "Structure and Function of the Cytoskeleton" in Paris. I had a bit off a rough start since the airline insisted on checking in my poster roll at the gate and then loosing it somehow. Luckily, there are copy shops in the area so now I can focus on the science!
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Reposted by Tom Golde
Marija Matejčić (mateytch-itch) @marija-matejcic.bsky.social · 24/02/2026
Tissue mechanics and synth morphogenesis folks, bump on this: Would you or someone in your lab be up for a video of a protocol you use getting recorded? The tips and tricks, the hard-to-explain-without-seeing-it-done? In the name of standardization and reproducibility in the field: get in touch! 🫀
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Reposted by Tom Golde
Marija Matejčić (mateytch-itch) @marija-matejcic.bsky.social · 16/12/2025
I am putting together a collection of video-protocols we (will) use in tissue mechanics research🌀 I hope to help consolidate established methods, but also showcase a few up-and-coming ones in our blooming field. Abstract submission by March 2026! Get in touch✨ #JoVETissueMech #ReproducibleTissueMech
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Tom Golde @tomgolde.bsky.social · 15/11/2025
Today I'm traveling to Portimao, Portugal to play with the German Men's Masters National team at the World Beach Ultimate Championships 2025. Wish me luck. wbuc.sport
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Tom Golde @tomgolde.bsky.social · 04/09/2025
Thanks Nimesh! Lets hope that the reviewers are as excited about our papers as we are.
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Tom Golde @tomgolde.bsky.social · 02/09/2025
Check out the preprint of my main work in the lab of @xaviertrepat.bsky.social @IBECBarcelona. Many thanks to all the people involved!
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Tom Golde @tomgolde.bsky.social · 03/07/2025
I'm proud to contributing to the development of the experimental system of this amazing study. I heard @onenimesa.bsky.social will do a whole thread soon. And maybe we have even more in the pipeline...
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Reposted by Tom Golde
Pau Guillamat @pauguillamat.bsky.social · 30/06/2025
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials. www.biorxiv.org/content/10.1... #ActiveMatter #TissueEngineering
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Reposted by Tom Golde
epithelial mechanics fan club @epimechfc.bsky.social · 08/06/2025
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations? I'm @juliaeckert.bsky.social. Let's explore some analysis software!‬
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Tom Golde @tomgolde.bsky.social · 07/02/2025
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Tom Golde @tomgolde.bsky.social · 13/12/2024
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Tom Golde @tomgolde.bsky.social · 04/12/2024
Great stuff from our lab!
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Tom Golde @tomgolde.bsky.social · 18/11/2024
Hello world! I wrote something about intermediate filaments and epithelial mechanics back on twitter. But you can also find it here :)
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