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Winston Timp

@timp0.bsky.social
185 followers 34 following 6 posts

timplab.org

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Winston Timp @timp0.bsky.social · 19/11/2025
We are excited to announce our most recent preprint “Single-cell long-read sequencing of the experience-induced transcriptome” (www.biorxiv.org/content/10.1...) led by @sheridan in collaboration with Richard Huganir. A few highlights:
biorxiv.org
Single-cell long-read sequencing of the experience-induced transcriptome
Neural activity drives transcriptional events that are critical for learning. Activity-induced transcript isoform expression and alternative splicing are cell-type specific events typically obscured b...
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Reposted by Winston Timp
David Schoppik @schoppik.com · 31/05/2025
Here's the White House's proposed reorganization of NIH institutes & budgets. Details in: www.hhs.gov/sites/defaul...
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Reposted by Winston Timp
Jim Shaw @jimshaw.bsky.social · 28/05/2025
Announcing myloasm, a new long-read (ONT R10/PacBio) metagenome assembler that I've been working on during my postdoc in the Heng Li lab (@lh3lh3.bsky.social). myloasm-docs.github.io
myloasm-docs.github.io
myloasm - metagenomic assembly with (noisy) long reads
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Reposted by Winston Timp
Simon Fisher @profsimonfisher.bsky.social · 09/04/2025
Telomere-to-telomere genome sequences of six ape species: chimpanzee, bonobo, gorilla, Bornean & Sumatran orangutan, & siamang! Invaluable resource for future evolutionary studies of humans & our closest living relatives. Kateryna Makova, @aphillippy.bsky.social, Evan Eichler & co in @nature.com.🙌🧬🧪
nature.com
Complete sequencing of ape genomes - Nature
Complete sequences of chromosomes telomere-to-telomere from chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang provide a comprehensive and valuable resource for future evol...
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Reposted by Winston Timp
Fritz Sedlazeck @sedlazeck.bsky.social · 03/04/2025
Long reads such as @nanoporetech.com or @pacbio.bsky.social can provide insights into epigenetic. We @yileifu.bsky.social & @timp0.bsky.social )summarize the latest #Bioinformatics approaches & why this matters! Out now @natrevgenet.bsky.social at: bit.ly/4cjxUtl @bcmhouston.bsky.social @jhu.edu
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Yilei Fu @yileifu.bsky.social · 29/03/2025
We summarized state-of-the-art computational methods for DNA methylation analysis using long-read sequencing, covering everything from base calling to sample-level, cell-type-level, and even population-scale analysis. Huge thanks to @sedlazeck.bsky.social and @timp0.bsky.social for this great work!
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Reposted by Winston Timp
Aaron Quinlan (he/him) @aaronquinlan.bsky.social · 13/01/2025
The abstract deadline for Biology of Genomes is a month away. We hope to see you there! meetings.cshl.edu/meetings.asp...
meetings.cshl.edu
Biology of Genomes
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
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