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The Society for Functional Precision Medicine

@thesfpm.bsky.social
285 followers 1 following 18 posts

Our mission is to improve patient care by advancing functional precision medicine through research, education, clinical implementation, and collaboration with academia, industry, regulators, and patients. Join us: www.sfpm.io

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The Society for Functional Precision Medicine @thesfpm.bsky.social · 27/11/2025
Please congratulate our incoming leaders, whose terms will officially begin on Dec 1! Co-Presidents Jesse Boehm, PhD Alice Soragni, PhD @alice.soragnilab.com Secretary Keith Ligon, MD, PhD Board Member At-Large Noah Berlow, PhD We offer our deep appreciation to the outgoing Board members.
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 11/11/2025
𝗦𝗙𝗣𝗠 𝗠𝗲𝗺𝗯𝗲𝗿𝘀 – 𝗬𝗼𝘂𝗿 𝗩𝗼𝗶𝗰𝗲 𝗠𝗮𝘁𝘁𝗲𝗿𝘀! Voting is now open for the SFPM Board Member Elections! This is your chance to help shape the future of our organization by selecting the leaders who will represent and guide our mission. ✅ Vote now: sfpm.membershiptoolkit.com
sfpm.membershiptoolkit.com
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The Society for Functional Precision Medicine
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 11/11/2025
𝗦𝗙𝗣𝗠 𝗠𝗲𝗺𝗯𝗲𝗿𝘀 – 𝗬𝗼𝘂𝗿 𝗩𝗼𝗶𝗰𝗲 𝗠𝗮𝘁𝘁𝗲𝗿𝘀! Voting is now open for the SFPM Board Member Elections! This is your chance to help shape the future of our organization by selecting the leaders who will represent and guide our mission. ✅ Vote now: sfpm.membershiptoolkit.com
sfpm.membershiptoolkit.com
The Society for Functional Precision Medicine - Login
The Society for Functional Precision Medicine
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 08/10/2025
🚨Excited to announce the seminar by Kushtrim Kryeziu, PhD (Oslo University) on "Functional Precision Oncology for Metastatic Colorectal Cancer". Join us TODAY, at 12 PM EDT, open to everyone! Don't miss it and consider joining the SFPM www.sfpm.io/seminars
sfpm.io
Seminars | SFPM
The SFPM Seminar series is for those interested in the use of assaying technology to further biomarker discovery, drug R&D and personalized healthcare outcomes.
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Soragni:Lab @alice.soragnilab.com · 29/09/2025
What incredible news today. I feel so grateful to have worked closely with Tony over the years and to have witnessed firsthand his vision, energy, and commitment to advancing functional precision medicine. I cannot think of a steadier (and more needed) force at the NCI at this time /n
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 29/09/2025
We want to congratulate our President, Dr. Tony Letai, on his appointment as Director of the NCI. This announcement marks an historic moment for cancer research. Dr. Letai has been a tireless advocate and visionary leader for functional precision medicine 🧵 www.nih.gov/news-events/...
nih.gov
Secretary Kennedy Swears in Dr. Anthony Letai as Director of the National Cancer Institute
Dr. Letai will serve as NCI’s 18th director.
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 17/09/2025
We were honored to host Jens M. Kelm, PhD (PreComb Therapeutics) for our September seminar. Dr. Kelm shared insights on: 🎯 Dynamic Drug Response Profiling at Scale for Functional Precision Oncology If you missed the live session, you can now watch it here: www.youtube.com/watch?v=hIkR...
youtube.com
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 08/09/2025
✨ Excited to announce a talk by Jens M. Kelm, PhD (Founder and CSO PreComb Therapeutics AG) on "Dynamic Drug Response Profiling at Scale for Functional Precision Oncology", Join us next Wednesday, September 10, 2025, at 12 PM EDT. Don't miss it! www.sfpm.io/seminars
sfpm.io
Seminars | SFPM
The SFPM Seminar series is for those interested in the use of assaying technology to further biomarker discovery, drug R&D and personalized healthcare outcomes.
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 10/06/2025
Join us this Wednesday 06/11 @ 12:00 PM EST for our monthly SFPM seminar! Dr. Chris Steffi from CompagOs will discuss: "Pioneering Solutions to Understand, Diagnose and Treat Bone Conditions" More info & link to join: www.sfpm.io/seminars
sfpm.io
Seminars | SFPM
The SFPM Seminar series is for those interested in the use of assaying technology to further biomarker discovery, drug R&D and personalized healthcare outcomes.
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 03/06/2025
Precision approaches to tackle acquired resistance to cancer, including model-based functional strategies: www.nature.com/articles/s41...
nature.com
Acquired resistance in cancer: towards targeted therapeutic strategies - Nature Reviews Cancer
Acquired therapeutic resistance is a key contributor to cancer treatment failure, requiring new approaches to address its complex mechanisms. In this Roadmap, Soragni, Knudsen and colleagues discuss t...
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Michael Hoffman @michaelhoffman.bsky.social · 12/03/2025
In panel discussion on regulatory and non-regulatory challenges to the wide adoption of precision diagnostics. Chair Tony Letai. #AACRprecmed25 🧪🧬🖥️
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Michael Hoffman @michaelhoffman.bsky.social · 12/03/2025
Now: Peter Horak. #AACRprecmed25 🧪🧬🖥️
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Michael Hoffman @michaelhoffman.bsky.social · 12/03/2025
Now: Keith Ligon. #AACRprecmed25 🧪🧬🖥️
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 12/03/2025
Two of our Board members, Dr. Letai and Dr. Ligon, are part of this #AACRPM25 panel focused on regulatory and non-regulatory challenges to the wide adoption of precision diagnostics
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 12/03/2025
Join us *today* Wednesday 03/12 @ 12:00 PM EST for our monthly SFPM seminar! Dr. Perova from EMBL-EBI will discuss: "Leveraging CancerModels.Org: enhancing precision oncology through collaborative cancer model resources" More info: www.sfpm.io/seminars
sfpm.io
Seminars | SFPM
The SFPM Seminar series is for those interested in the use of assaying technology to further biomarker discovery, drug R&D and personalized healthcare outcomes.
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Michael Hoffman @michaelhoffman.bsky.social · 11/03/2025
Now: Keith Flaherty: Targets and therapeutics in need of functional insights to guide drug development in solid tumors #AACRprecmed25 🧪🧬🖥️
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Michael Hoffman @michaelhoffman.bsky.social · 11/03/2025
Continued 2: KF: Genetic evidence points to multiple resistance pathways #AACRprecmed25 🧪🧬🖥️ aacrjournals.org/clincancerres/arti…
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Michael Hoffman @michaelhoffman.bsky.social · 11/03/2025
Now: Jeffrey Tyner: Functional omics for novel therapeutic combinations in myeloid malignancies #AACRprecmed25 🧪🧬🖥️
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Michael Hoffman @michaelhoffman.bsky.social · 11/03/2025
Continued 2: JT: Experimental approach: primary cells -> overnight exposure -> CITE-seq: dynamic changes and cell persistence under therapeutic selective pressure. With @wondermixtape.bsky.social #AACRprecmed25 🧪🧬🖥️
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Michael Hoffman @michaelhoffman.bsky.social · 11/03/2025
Now: Coleman Lindsley: Dyanmic assessment in leukemia. What is minimal residual disease and does it matter? #AACRprecmed25 🧪🧬🖥️
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Michael Hoffman @michaelhoffman.bsky.social · 11/03/2025
Now: Sascha Dietrich: Ex vivo drug response profiling for response and outcome prediction in hematologic malignancies #AACRprecmed25 🧪🧬🖥️
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Michael Hoffman @michaelhoffman.bsky.social · 11/03/2025
On my way to @theaacr.bsky.social special conference in cancer research: functional and genomic precision medicine in cancer. Who else will be there? @alice.soragnilab.com #AACRprecmed25 www.aacr.org/meeting/aacr...
aacr.org
AACR Special Conference in Cancer Research: Functional and Genomic Precision Medicine in Cancer: Different Perspectives, Common Goals
Overview for AACR Special Conference in Cancer Research: Functional and Genomic Precision Medicine in Cancer: Different Perspectives, Common Goals
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Soragni:Lab @alice.soragnilab.com · 11/03/2025
This first AACR meeting on functional and genomic precision medicine has officially started! Dr. Mardis gave the introductory remarks followed by our first plenary speaker, Dr. Flaherty, who will focus on the collision of genomic and functional precision medicine #AACRPM25
Elaine Mardis giving introductory remarksKeith Flaherty starting his lecture
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Joan Montero @joanmontero.bsky.social · 11/03/2025
Do not miss this great talk tomorrow at 5pm CET (12pm EDT): Zinaida Perova (EMBL) "Leveraging CancerModels.Org: Enhancing Precision Oncology Through Collaborative Cancer Model Resources". @thesfpm.bsky.social www.sfpm.io/seminars
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 12/02/2025
Join us *today* Wednesday 02/12 @ 12:00 PM EST for our monthly SFPM seminar! Dr. Andrew Satterlee from UNC will discuss overcoming systemic barriers to functional precision medicine using a versatile ex vivo model of patient brain tumors. More info: www.sfpm.io/seminars
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 29/01/2025
An exciting multicenter phase 2 functional precision medicine clinical trial showing how a rapid ex vivo venetoclax sensitivity assay was the strongest predictor for a favorable treatment response and survival in relapsed/refractory secondary AML ashpublications.org/blood/articl...
ashpublications.org
Ex vivo venetoclax sensitivity predicts clinical response in acute myeloid leukemia in the prospective VenEx trial
Key PointsBlast-specific ex vivo venetoclax sensitivity correlated strongly with treatment responses and predicted longer survival.VenEx trial showed that
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Soragni:Lab @alice.soragnilab.com · 13/12/2024
Very interesting functional precision medicine study: glioblastoma patient-derived organoids treated with dual-targeting EGFR-IL13Rα2 CAR-Ts mirrored clinical parameters www.cell.com/cell-stem-ce...
cell.com
Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy
Logun et al. report a unique phase 1 clinical trial design with parallel assessment of patients and rapidly generated patient-derived tumor organoids for CAR-T cell bioactivity in glioblastoma. They showed that cytokine release and the degree of cytolysis in glioblastoma organoids with autologous CAR-T treatment correlated with clinical patient metrics.
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 10/12/2024
Join us *tomorrow* Wednesday 12/11 @ 12:00 PM EST for our last monthly SFPM seminar of the year! Drs. Damle and Pillarisetty from @fredhutch.bsky.social will discuss tumor slice cultures as a window into the human TME. Info to join here: www.sfpm.io/seminars
sfpm.io
Seminars | SFPM
The SFPM Seminar series is for those interested in the use of assaying technology to further biomarker discovery, drug R&D and personalized healthcare outcomes.
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 09/12/2024
And we are back in business! Functional precision medicine folks are moving to Bluesky, and so are we. Find out more about what the Society for Functional Precision Medicine does and how to join here: sfpm.io
sfpm.io
The Society for Functional Precision Medicine
The SFPM arose to match cancer patients to their best therapies. Using patient-derived models, including organoids and 2D culture; and many readouts, including metabolic, morphologic and cell death m...
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Elizabeth McKenna @elizsmckenna.bsky.social · 27/09/2023
📢Announcing a call for commentaries! Cancer Discovery wants to hear YOUR thoughts that challenge existing paradigms/shed new light on emerging topics in cancer. Selected pieces will be published in April 2024 and showcased during #AACR24! Email cancerdiscovery@aacr.org with proposals by Nov. 1.
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The Society for Functional Precision Medicine @thesfpm.bsky.social · 19/09/2023
The Society for Functional Precision Medicine is officially on Bluesky! Hope to find some FPM aficionados on this platform as well. We will be posting updates from the Society as well as functional precision medicine news & papers in general. Learn more about us here: sfpm.io
sfpm.io
The Society for Functional Precision Medicine
The SFPM arose out of recognition of the unmet need in matching cancer patients to the therapies best suited for them. Through the use of functional assays, we hope to bridge the gap between patients ...
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