Throughout the world, peer review serves as the cornerstone of the scientific enterprise, providing rigorous quality control and building the confidence that underpins progress for both science and so...

Telomeres are nucleoprotein elements bound by shelterin that protect chromosome ends from DNA damage signalling and inappropriate repair. A defining architectural feature is the telomere loop (t-loop)...

Cicada Innovations is Australia's leading incubator for startups and scaleups working on deep tech science and engineering innovations.

Telomerase recruitment to telomeres is a tightly regulated process which is stimulated by replication stress. Here, the authors identify that nuclear filamentous actin is important for interaction bet...

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Emerging evidence suggests that, following genotoxic therapy, it is the repair of DNA double-strand breaks, rather than the damage itself, that frequently drives cancer cell death.

Nature Reviews Molecular Cell Biology - Changes in nuclear and genome organization promote the repair of DNA double-strand breaks and genome stability. Processes that are involved include the...

Nature Communications - Here the authors reveal how telomeres signal mitotic stress. A key protein network alters their structure exposing telomere ends to signal mitotic stress, ultimately...

Here the authors reveal how telomeres signal mitotic stress. A key protein network alters their structure exposing telomere ends to signal mitotic stress, ultimately triggering a controlled DNA damage...

Social DNAing Webinar Series, sponsored by the Cancer Genomics and Epigenomics Program at Columbia University, aims to provide a virtual meeting room for the genomic instability community worldwide.

The Trump administration has put a hold on all federal financial grants and loans, affecting tens of billions of dollars in payments.