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Terje Johansen - Autophagy Research Group

@terjejohansen.bsky.social
294 followers 158 following 8 posts

Professor and leader of the Autophagy Research Group at UiT The Arctic University of Norway. Engaged in curiosity driven basic research into molecular mechanisms and roles of selective autophagy in cell signaling and disease mechanisms.

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Terje Johansen - Autophagy Research Group @terjejohansen.bsky.social · 19/12/2025
A C-terminal cytoplasmic retention motif and nuclear localization signal regulates nuclear import of TP53INP2 url: journals.biologists.com/jcs/article/... BIG Congratulations to all authors and particularly to the first author Birendra Kumar Shrestha who did a fantastic job !
journals.biologists.com
A C-terminal cytoplasmic retention motif and nuclear localization signal regulates nuclear import of TP53INP2
Highlighted Article: The transcriptional coactivator TP53INP2 is degraded by nuclear proteasomes under basal conditions. Upon starvation and exposure to various chemical stressors, a conserved cytopla...
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Terje Johansen - Autophagy Research Group @terjejohansen.bsky.social · 06/07/2025
WSTF nuclear autophagy regulates chronic but not acute inflammation is published in Nature😀 nature.com/articles/s41... Congratulations to all collaborating groups! Fantastic effort by first author Yu Wang! Kudos to Zixhun Dou for leading the entire project!😀
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Reposted by Terje Johansen - Autophagy Research Group
Waggoner Lab @labwaggoner.bsky.social · 02/07/2025
WSTF nuclear autophagy regulates chronic but not acute inflammation @nature.com @terjejohansen.bsky.social www.nature.com/articles/s41...
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Terje Johansen - Autophagy Research Group @terjejohansen.bsky.social · 07/04/2025
Caloric restriction prevents inheritance of polycystic ovary syndrome through oocyte-mediated DNA methylation reprogramming. Liu, Yue et al. Cell Metabolism, Volume 37, Issue 4, 920 - 935.e6 doi.org/10.1016/j.cm...
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Reposted by Terje Johansen - Autophagy Research Group
satooze.bsky.social @satooze.bsky.social · 26/03/2025
I am looking for a post/doc! Are you motivated to study the fundamental questions in autophagy? Have a look!
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Reposted by Terje Johansen - Autophagy Research Group
Claudine Kraft's Lab @kraftlabfr.bsky.social · 07/01/2025
🚨 Paper Alert! We’re starting off the year with our latest publication in @naturecellbiology.bsky.social on the role of phase separation in selective autophagy initiation! This work was a close and exciting collaboration with @wilflinglab.bsky.social 🔗 nature.com/articles/s41... Here's a thread👇
nature.com
Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy - Nature Cell Biology
Licheva, Pflaum, Babic, Mancilla et al. show that low-affinity cargo–receptor interactions promote autophagy receptor mobility and condensation of the scaffold protein Atg11 to trigger initiation hub ...
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Terje Johansen - Autophagy Research Group @terjejohansen.bsky.social · 30/11/2024
Congratulations with a great paper and a massive amount of important work from Serhiy Pankiv in Anne Simonsen´s group creating a gold chest of reagents for studies of BEACH domain proteins!😀👍 doi.org/10.1083/jcb....
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Terje Johansen - Autophagy Research Group @terjejohansen.bsky.social · 22/11/2024
Exciting study about Gliocidin, a nicotinamide-mimetic prodrug, that targets glioblastoma!!! Chen, YJ., Iyer, S.V., Hsieh, D.CC. et al. Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma. Nature (2024). doi.org/10.1038/s415...
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Reposted by Terje Johansen - Autophagy Research Group
Jennifer Palmer @jenniferepalmer.bsky.social · 13/11/2024
To celebrate the move to Bluesky, here is our recent review on autophagy, ageing, and age-related neurodegeneration: www.cell.com/neuron/fullt...
cell.com
Autophagy, aging, and age-related neurodegeneration
This review discusses the links between the autophagy pathway, aging, and age-associated neurodegeneration in Alzheimer’s, Parkinson’s, motor neuron, and Huntington’s diseases. The authors highlight t...
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Reposted by Terje Johansen - Autophagy Research Group
Ariel K. Frame @arielframe.bsky.social · 31/10/2024
Fantastic study! Highly worth checking this out www.nature.com/articles/s41... for those interested in #aging #drosophila #mitochondria #autophagy
nature.com
Accumulation of F-actin drives brain aging and limits healthspan in Drosophila - Nature Communications
Changes to actin dynamics during brain aging are not well understood. Here, the authors report that there is an age-related increase in F-actin in Drosophila brain which disables autophagy within the ...
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