Bitterness is a key taste modality mediated in vertebrates by TAS2R G protein coupled receptors, which also function in diverse extraoral tissues. Recent cryo EM structures have revealed a non classic...

Bitter taste receptors (TAS2Rs) are G- protein coupled receptors that detect chemically diverse compounds, including many clinically used drugs. TAS2R14 is expressed in many extraoral tissues and is a...

Nature Structural & Molecular Biology - Bitter taste receptors are a subtype of G-protein receptors that are activated by a variety of ligands, leading to bitter taste sensation. Two studies...

Scientists reflect on insights from the Human Cell Atlas.

Abstract. BitterDB (http://bitterdb.agri.huji.ac.il) was introduced in 2012 as a central resource for information on bitter-tasting molecules and their rec