Abstract. Models of tumor drug response have illuminated important concepts in oncology, but there remains a need for theory that combines intra-tumor and inter-patient heterogeneity to explain patien...

TO THE AMERICAN PEOPLE We all rely on science. Science gave us the smartphones in our pockets, the navigation systems in our cars, and life-saving medical care. We count on engineers when we drive acr...

The Trump administration hobbles research and endangers the public health.

c-MYC copy number gain due to trisomy 8 drives S100A9-mediated inflammation and expansion of hematopoietic stem cells and progenitors in the bone marrow, thus trisomy 8 defines a new subset of myelopr...