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Dan Bachovchin

@bachovchin.bsky.social

422 followers 125 following 1 posts

Scientist at Memorial Sloan Kettering Cancer Center

Posts Replies Media

Reposted by Dan Bachovchin

Seth Masters @sethlucianmasters.bsky.social · 07/12/2024

A starter pack for anyone interested in #autoinflammation and #autoinflammatory diseases. Please let me know if you’d like to be added. go.bsky.app/5M6obrp

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Reposted by Dan Bachovchin

Abhishek Chatterjee @achemsynbio.bsky.social · 01/12/2024

Got the chance to put together the "Click of Chemical Biologists" starter pack v1 and v2 over the Thanksgiving Break. Feel free to ping me on who else I might be missing! V1: go.bsky.app/3P5i7nJ V2: go.bsky.app/Cr4ej7

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Dan Bachovchin @bachovchin.bsky.social · 29/11/2024

Check out our lab's latest paper describing a mutually inhibitory complex between DPP9 and KEAP1 www.jbc.org/article/S002...

jbc.org

The Serine Protease DPP9 and the Redox Sensor KEAP1 Form a Mutually Inhibitory Complex

Synthetic inhibitors of the serine protease DPP9 activate the related NLRP1 and CARD8 inflammasomes and stimulate powerful innate immune responses. Thus, it seems plausible that a biomolecule similarl...

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