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Jake Wintermute

@synbio1.bsky.social
1.8K followers 428 following 854 posts

Synthetic Biologist - Foundry Theorist foundrytheory.substack.com stay humble biodesigners

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Jake Wintermute @synbio1.bsky.social · 7h
I heard somewhere that AI will solve plastic recycling in 10 years so this is probably fine
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Jake Wintermute @synbio1.bsky.social · 12/10/2026
East coast is the yeast coast
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Jake Wintermute @synbio1.bsky.social · 01/10/2026
“AI can’t possibly know everything about biotech because some of it is tacit knowledge you can only experience first hand.” The tacit knowledge:
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Jake Wintermute @synbio1.bsky.social · 15/09/2026
Sell me this bioproduct
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Jake Wintermute @synbio1.bsky.social · 14/09/2026
I'd like to get a 90s-era medical device console like this and install some kind of AI soundboard in it so it can be my sassy lab companion
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Jake Wintermute @synbio1.bsky.social · 14/07/2026
Nobody there cares but I do it anyway
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Jake Wintermute @synbio1.bsky.social · 11/07/2026
Can anyone who played CELLQuest on the original Becton Dickinson tell me if it was fun? Is it worth trying to vibe code an emulator for some retro gaming?
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Jake Wintermute @synbio1.bsky.social · 27/05/2026
I look forward to the day when every lab instrument runs linux and the entire UI is just an MCP for my agents
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Jake Wintermute @synbio1.bsky.social · 13/05/2026
If weeds can overgrow a fake lawn then it stands to reason that you could develop a strain of grass that would functionally replace the fake lawn except be real
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Jake Wintermute @synbio1.bsky.social · 30/04/2026
How it feels to do biotech in 2026
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Jake Wintermute @synbio1.bsky.social · 28/04/2026
Bioproduct idea gluten-free damp dusters for the market of people with celiac disease who want to eat their scrub daddies
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Jake Wintermute @synbio1.bsky.social · 24/04/2026
I am literally begging you to start a biotech company, literally any biotech company, and incorporate slop maximalism into your branding I am in love with biotech slop maximalism. I will do free work for you. I will shill whatever bioproduct or AI model thing you sell.
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Jake Wintermute @synbio1.bsky.social · 20/04/2026
1) Apparently snails can eat graffiti 2) Apparently snails actively seek out graffiti to eat 3) ??? 4) Start a biotech company that sells snails for graffiti removal
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Jake Wintermute @synbio1.bsky.social · 11/04/2026
I will personally award the Nobel Prize in Chemistry to the first person who engineers a peptide that can do the worm
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Jake Wintermute @synbio1.bsky.social · 11/04/2026
Hands-free lab automation solves this problem
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Jake Wintermute @synbio1.bsky.social · 09/04/2026
We know that AI increases the value of human biological data. But by how much? Super interesting to see a specific class of human biological data assigned a spot price in a real market event
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Jake Wintermute @synbio1.bsky.social · 08/04/2026
Lab coats should have elastic scrunchies on the sleeves
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Jake Wintermute @synbio1.bsky.social · 06/04/2026
16 years ago I blew off my thesis research for one day to make a YouTube video about plasmids www.youtube.com/watch?v=pNeC... Today I'm in the plasmid sequencing tutorials for Plasmidsaurus www.youtube.com/watch?v=pNeC... The trick to having a fun career in science is say yes to random fun things
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Jake Wintermute @synbio1.bsky.social · 24/03/2026
Me when I click on an in-line citation in an online article and it takes me to the references section of the same article instead of opening the new article in a new tab
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Jake Wintermute @synbio1.bsky.social · 26/02/2026
Bioproduct idea: sooner oats
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Jake Wintermute @synbio1.bsky.social · 25/02/2026
We’re so blessed that evolution made the shape of eggs be the literal only possible shape for eggs that isn’t deeply unsettling
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Jake Wintermute @synbio1.bsky.social · 24/02/2026
Biotech startups 0.0003 nanoseconds after the lab team ships a breakthrough drug to clinical trials
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Jake Wintermute @synbio1.bsky.social · 22/02/2026
The funniest version of the future is the one where we invent ASI only to watch it immediately start culturing brain cells to invent ASSI www.cell.com/cell-reports...
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Jake Wintermute @synbio1.bsky.social · 05/02/2026
Have fun in the small pumpkin underclass losers
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Jake Wintermute @synbio1.bsky.social · 02/02/2026
Me and everyone who keeps calling it Pichia pastoris holding out against the attempt to rename it Komagataella phaffii
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Jake Wintermute @synbio1.bsky.social · 01/02/2026
How it feels to start opening tabs on a new research project
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Jake Wintermute @synbio1.bsky.social · 30/01/2026
There are still some good gene splicer jobs
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Jake Wintermute @synbio1.bsky.social · 29/01/2026
You must assemble the 4 lost parafilms of type "L," "N," "O" and "P"
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Jake Wintermute @synbio1.bsky.social · 27/01/2026
The children yearn for bioproducts
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Jake Wintermute @synbio1.bsky.social · 27/01/2026
fruitpilled peachcel
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Jake Wintermute @synbio1.bsky.social · 27/01/2026
I'll give you the secret tech for good popcorn: nutritional yeast
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Jake Wintermute @synbio1.bsky.social · 27/01/2026
The good version of the future includes a decentralized bioeconomy supporting lots of good green-collar jobs in bioproducts and bioservices Sourdough microbakeries hint at what that future might look like www.nytimes.com/2026/01/26/d...
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Jake Wintermute @synbio1.bsky.social · 26/01/2026
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Jake Wintermute @synbio1.bsky.social · 26/01/2026
The fancy popcorn from the organic market is bad at popping compared to the cheap popcorn from the normal grocery store and I’m tired of pretending it’s not
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Jake Wintermute @synbio1.bsky.social · 24/01/2026
Techbio / Biotech
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Jake Wintermute @synbio1.bsky.social · 21/01/2026
When you work in a yeast lab and you pause a moment to enjoy the aromas of the yeast
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Jake Wintermute @synbio1.bsky.social · 19/01/2026
I don't want to be the main character I want to be the quest giver
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Jake Wintermute @synbio1.bsky.social · 17/01/2026
Mutagen Man, Living Ooze
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Jake Wintermute @synbio1.bsky.social · 17/01/2026
This vintage Abcam fridge magnet does me so right It’s odd, it’s playful, it’s memorable. But what I like best is the way you can tell if reflects a real human’s sense of humor. It wasn’t designed by committee. More marketing like this please biotech companies
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Jake Wintermute @synbio1.bsky.social · 16/01/2026
But there's nothing like the warm sound of an orbital shaker
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Jake Wintermute @synbio1.bsky.social · 12/01/2026
This is the strongest argument in favor of automated labs
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Jake Wintermute @synbio1.bsky.social · 11/01/2026
I've often daydreamed about fantastically large fruits and vegetables, living in a pumpkin house, boats made of watermelons, things of that nature But maybe I need to re-imagine that future because these large carrots are actually quite unsettling
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Jake Wintermute @synbio1.bsky.social · 09/01/2026
At first I thought this picture was just somebody from woodgang hornyposting so imagine my delight to see bark-dwelling microbes on the cover of science magazine www.science.org/doi/10.1126/...
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Jake Wintermute @synbio1.bsky.social · 08/01/2026
Scientists often assume that "the public" has an innate and knee-jerk opposition to GMOs, lab-grown meat or other novel bioproducts But when you make something people really want it turns out they have a higher weirdness tolerance than you might expect
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Jake Wintermute @synbio1.bsky.social · 08/01/2026
This is how I feel about attempts to build a virtual cell model
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Jake Wintermute @synbio1.bsky.social · 07/01/2026
Biotech goals
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Jake Wintermute @synbio1.bsky.social · 06/01/2026
Writing your lover a note on paper made from your own hair is the kind of high-upside romantic bet you can only make with a bio-based product
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Jake Wintermute @synbio1.bsky.social · 02/01/2026
I wonder if we could replicate this pipeline to get more of the the fitness-style biohacking community interested in fundamental biology and lab-style biohacking
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Jake Wintermute @synbio1.bsky.social · 31/12/2025
When you're brainstorming about bioproduct ideas one thing you look for is signs of an unmet market need
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Jake Wintermute @synbio1.bsky.social · 29/12/2025
We could have GFP cats just sayin
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