iiinova — where your digital self keeps evolving

Christy Collins @sun-in-winter12.bsky.social · 04/04/2026

Bookmarking this- I’ll need to evaluate further, but this seemed to give me a much-needed boost today! 🙏 Acupuncture was one of the very first things that helped with my #LongCOVID. Today I decided to see if I could recreate the benefits myself… ✨ bit.ly/12acub

youtu.be

Acupressure for Yourself

YouTube video by UMMCVideos

021 0

Christy Collins @sun-in-winter12.bsky.social · 04/02/2026

Great info here! 🧵on treating microclots in #LongCOVID

030 0

Christy Collins @sun-in-winter12.bsky.social · 04/02/2026

Great thread! Thanks for sharing this 🙏

120 0

Christy Collins @sun-in-winter12.bsky.social · 04/02/2026

Here it is: Part 2 in my series about how I recovered from Long COVID PEM ✨ One of the most important things I did was use immune stimulants to clear persistent SARS-CoV-2 virus. However, these can be very rough on the body. Here’s what I did to stabilize my symptoms BEFORE treatment 👇 #longcovid

open.substack.com

My Recovery from Long COVID PEM, Part 2: Stabilizing my Symptoms with Microclot Treatment

How I stabilized my symptoms before trying immune stimulants

040 0

Reposted by Christy Collins

derek guy @dieworkwear.bsky.social · 25/01/2026

The Washington Post published a clear video of federal agents removing Alex Pretti's handgun moments before he was fatally shot. There's nothing in the video to suggest Pretti even reached for his weapon. wapo.st/49Zqv1L

808207377937 0

Reposted by Christy Collins

Acyn @acyn.bsky.social · 25/01/2026

Reporter: You received a letter from AG Pam Bondi making several demands…. Walz: I would just give a pro tip to the AG. There's 2 million documents in the Epstein files we're still waiting on. Go ahead and work on those

9244744513584 0

Reposted by Christy Collins

Olga Nesterova @onestpress.onestnetwork.com · 25/01/2026

Minnesota National Guard members have arrived at a federal building and were directed to distribute donuts, coffee, and hot chocolate to anti-ICE protesters. Guard members were issued reflective vests so they would not be mistaken for federal agents.

15775579213725 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

this is not the end - will discuss Pillars 2 and 3 in a bit!!!!!

020 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

I also used things like: coconut oil - powerful antiviral Brazil nuts for selenium - glutathione precursor miso + yogurt for probiotics - immunomodulatory properties Some of this I'd started earlier - more info in my previous update here: longcovidbegone.substack.com/p/a-positive... 12/

longcovidbegone.substack.com

A Positive Update: How I stopped needing blood thinners for Long Covid

Turning a corner, June 2024

110 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

There's a lot you can do to make it more difficult for the virus to invade your cells. For example, Omega-3 and alpha lipoic acid can help strengthen your cells' membranes so the virus has to work harder to break through. 11/ bit.ly/41x8Ue1

bit.ly

Omega-3 & COVID-19: What the Studies Say

Delve into omega-3 and COVID-19 research: What the studies say. Stay informed about omega-3's potential benefits during the pandemic.

120 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

Glutathione specifically has been shown to improve the immune response. It plays an important role in t-cell and natural killer cell function - two types of cells which we need to clear virally infected cells! 10/

Screenshot of title and abstract from this paper: https://pubmed.ncbi.nlm.nih.gov/40184815/

highlighted text says: "Overall, our study identifies dysregulated GSH metabolism as a key driver of NK cell dysfunction in acute leukemia and suggests that GSH-based interventions may provide a promising strategy to enhance NK cell-mediated immunotherapies."

130 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

Glutathione, CoQ10, alpha lipoic acid can all help with this. Glutathione in particular has been shown to have multiple antiviral properties. It's often depleted in chronic infections such as HIV, and supplementing it can help restore immune function. 9/

screenshot of title and abstract of this paper: https://bit.ly/45ZD1ft

highlighted text says: An imbalance in GSH is observed in a wide range of pathologies, such as cancer, neurodegenerative diseases, cystic fibrosis (CF), several viral infections including HIV-1, as well as in aging. Several reports have provided evidence for the use of GSH and molecules able to replenish intracellular GSH levels in antiviral therapy.

120 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

1: Mitochondrial & Metabolic Support Viruses take over our mitochondria to replicate. The more difficult we can make for it to do that, by keeping our own human chemical reactions going, the more we can slow the virus down. 8/

120 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

My goal was to do everything I could to both fight the virus directly, as well as optimize my immune response. ✨My plan had 3 main pillars:✨ 1) Mitochondrial & Metabolic Support 2) Antivirals 3) Immune Stimulants 7/

120 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

I planned my treatment meticulously before I started. With a virus that was possibly actively replicating, I knew I had to hit it as hard as I could, all at once. I didn’t want to treat it halfway, and give it the chance to mutate. So I planned a siege. 6/

120 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

The viral persistence hypothesis had always terrified me. In the back of my mind, I think I always knew it was my root cause - but I was scared to face it. Once I read this preprint, I decided it was time. 5/

120 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

My own anti-spike antibodies immediately following my Feb 2023 acute infection were off the charts - >12,500 U/mL. Compare this to Oct 2021 when I'd only been vaccinated - they were 2000 U/mL. 4/

Screenshot of my lab results for anti-spike antibodies. The amount says >12,500 U/mL

120 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

In this paper, Rodriguez et al studied biomarkers from a cohort of patients with severe Long COVID. What they found suggested a possible relationship between high anti-spike antibodies, a restrained T cell response, and viral persistence in LC. 3/ bsky.app/profile/sun-...

120 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

In spring 2024, I put together a 3-part treatment plan based on the idea that I needed to clear the SARS-CoV-2 virus from my body. While viral persistence may not be the root cause for everyone with Long Covid, I was strongly influenced by this 2024 preprint... 2/

120 0

Christy Collins @sun-in-winter12.bsky.social · 26/11/2025

✨How I Recovered from Long Covid PEM:✨ Hey everyone, I've waited a while to share this - I wanted to make sure my improvements stuck. It's been almost a year now, in total - wow! 1/ longcovidbegone.substack.com/p/my-recover...

longcovidbegone.substack.com

My Recovery from Long Covid PEM: Introduction

How I targeted the SARS-CoV-2 virus, and got rid of my post-exertional malaise.

150 0

Reposted by Christy Collins

Jon Douglas @atranscendedman.bsky.social · 29/08/2025

La Jolla researchers screened 56 small molecules and found a new class that binds ETF1, a host protein, to disrupt viral ribosomal frameshifting. These compounds blocked SARS-CoV-2, HIV, and other viruses without harming cells. www.biorxiv.org/content/10.1...

biorxiv.org

153 0

Christy Collins @sun-in-winter12.bsky.social · 25/08/2025

Thanks for sharing! (I was gonna put it on here too but hadn’t had a chance yet- appreciate your spreading the word! 🙂)

110 0

Christy Collins @sun-in-winter12.bsky.social · 25/08/2025

Happy to! Thanks so much for everything you and your colleagues are doing! 🙏

010 0

Christy Collins @sun-in-winter12.bsky.social · 25/08/2025

Wow... seems like pretty strong evidence for SARS-CoV-2 persistence in pediatric Long COVID....

051 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

We know there is likely more than one root cause of LC, and some people don’t make antibodies at all. However I think it’s AMAZING that a phenotype of viral persistence has been clearly defined 🎉 We’ve moved past asking whether the virus is still present, to proving WHY 16/

130 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

Of course, the #1 thing to take away from this is that the authors are now hypothesizing about a cure. That’s right, they wrote the word CURE ✨ Specifically, antivirals (+presumably other strategies) to remove the persistent virus that our t-cells could not. /15

Screenshot from the paper. Highlighted text says:

"All in all, our results suggest that a persistent viral reservoir is likely contributing to Long COVID pathology and ongoing efforts (NCT05823896) to remove such persisting viruses with prolonged antiviral therapies are important and hold clinical promise for delivering a much-needed cure to the community of Long COVID sufferers worldwide."

111 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

Basically, we may have evolved this restrained t-cell response for a reason. The authors say it may be a way for women's bodies to conserve energy for reproduction, and children's bodies for growth. Now, this trait that was helpful to us in the past is now harming us 14/

010 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

Senior author @petterbrodin.bsky.social explains that the answer may lie in our genetics, as well as the fact that the immune system operates differently at different stages of life. 13/

100 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

They started to ask the question: Why does Long Covid more often affect people we'd expect to have STRONGER immune systems? Why do children and women of child-bearing age disproportionately develop LC, compared to those at high risk of severe acute disease? 12/

210 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

Why does this happen? When the researchers took steps to select the patients who were the sickest, following a mild infection, their patient population came out to a 87% female. With an average age of 48. 11/

131 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

Personally, I totally believe this is what happened to me. According to the authors, antibody responses normally wane in 6 months, in people who fully recover. Meanwhile my anti-spike antibodies were just under 10K, 10 months following my acute infection 8/

Screenshot of my SARS-CoV-2 spike antibody result showing a level of 9,825.00 U/mL

110 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

Our T-cells fail to fully fight off the virus in the initial stage, allowing it to establish reservoirs. Our B-cells then try to pick up the slack by producing tons of antibodies, but can't seem to fully clear it. So we end up with viral persistence + high antibodies 7/

142 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

For some reason, this process seems to be “restrained” in LC patients. The team found the higher the level of anti-spike antibodies, the lower the person's rate of CD8+ clonal expansion. Essentially, the two responses are inversely correlated, when they're supposed to match 6/

110 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

Why would this occur? Normally when the immune system encounters a pathogen, the CD8+ T cells clone themselves to rapidly increase in number. www.akadeum.com/blog/t-cell-... 5/

akadeum.com

T Cell Clonal Expansion

Clonal expansion is the rapid division of genetically identical T cells, creating copies specific to invading pathogens for immune response.

100 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

So they looked to see what else was wrong. They found that compared to people who fully recovered, #pwLC tended to have much higher anti-spike antibodies. In some people, the level of antibodies actually went UP over time, instead of down. 4/

120 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

The researchers set out to discover what made these patients different. They looked for signs of viral persistence, such as spike protein in the blood. The problem was that different tests gave different results, and didn't always correspond with how the patients felt. 3/

110 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

In this study, researchers recruited out of LC clinics in Sweden and Belgium. They purposely chose patients with the most severe symptoms following a mild infection. The goal was to zero in on the root cause of LC, as opposed to organ damage from severe infection. 2/

120 0

Christy Collins @sun-in-winter12.bsky.social · 24/08/2025

Hey everyone, ICYMI I wanted to highlight this groundbreaking #LongCOVID preprint. Personally, I've found there may be a lot of truth to this idea: **High anti-spike antibodies that don’t wane 6 months after infection may be a sign of viral persistence** 1/ 👇 www.medrxiv.org/content/10.1...

medrxiv.org

Restrained memory CD8+ T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID

During the COVID-19 pandemic it was widely described that certain individuals infected by SARS-CoV-2 experience persistent disease signs and symptoms, Long COVID, which in some cases is very severe wi...

192 0

Christy Collins @sun-in-winter12.bsky.social · 30/12/2024

Glutathione and Coq10 help me immensely in the short term. I’m thinking of adding NAD+ injections as well. Long term, I think we need to clear the persistent virus…

040 0

Christy Collins @sun-in-winter12.bsky.social · 18/12/2024

#PwLC reading this… have you benefited from any treatments that would activate NK cells? Someone mentioned peptides- that’s a really promising area that I’ve been meaning to post about. Anything else you’ve tried? 11/

001 0

Christy Collins @sun-in-winter12.bsky.social · 18/12/2024

And of course, huge, huge thanks to @polybiorf.bsky.social for supporting this research. Can’t begin put into words how grateful I am, and what it means to actually be feeling hopeful at this point in my LC journey! This research is just truly incredible. 10/ bsky.app/profile/poly...

110 0

Christy Collins @sun-in-winter12.bsky.social · 18/12/2024

You can watch Dr. Tim Henrich explain their NK cell research, and the rationale for the Anktiva trial, at the 2024 @polybiorf.bsky.social Fall Symposium: 9/ youtu.be/nzwH556GsuU?...

youtu.be

PolyBio Fall 2024 Symposium

YouTube video by PolyBio Research Foundation

100 0