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Sudipta Mondal

@sudipta-cryoet.bsky.social
100 followers 292 following 6 posts

In situ structural biology enthusiast | chasing molecular machines in their native habitat #cryoET Postdoc @ParkLab Scripps

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Reposted by Sudipta Mondal
Ben Barad @baradlab.com · 12/12/2025
Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6... Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet
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Sudipta Mondal @sudipta-cryoet.bsky.social · 29/10/2025
Do #lipids carry the signatures of #evolution?🤔 In #Biochemistry Perspective, We 'provocatively' (as my former PhD guide & scientific guru Sankar put it ) propose an expanded view of the classic “lipid divide” idea feedback/critiques all welcome 🙌 #lipidtime pubs.acs.org/doi/10.1021/...
pubs.acs.org
An Integrative View on Multiple “Lipid Divide” Events as Hallmarks of Distinct Evolutionary Transitions
Lipids are fundamental to life, serving not only as membrane components but also as key players in signaling, energy storage, and cellular identity. While the well-known “lipid divide” between Bacteri...
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Reposted by Sudipta Mondal
Oli Clarke @olibclarke.bsky.social · 13/09/2025
This one is a bit of a departure from the usual and definitely a work in progress! We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below. Read on for details... 1/x
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Sudipta Mondal @sudipta-cryoet.bsky.social · 08/07/2025
#NotTheCover @cellpress.bsky.social ...but, we’re still pretty proud of it! 😄 Had an awesome time putting this together with the amazing @kfreeman.bsky.social and @raphaelpark.bsky.social What a ride! 🚀 #SciArt #CryoET #CryoEM Paper👉 www.cell.com/cell/fulltex...
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Reposted by Sudipta Mondal
RCSB Protein Data Bank @rcsbpdb.bsky.social · 18/05/2025
The very first structural images of a tuberculosis-fighting virus New insights could advance phage therapies for the world’s deadliest bacteria—including drug-resistant strains. www.scripps.edu/news...
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Reposted by Sudipta Mondal
Di Jiang @dijiang319.bsky.social · 16/05/2025
@science.org 🧫🧬❄️🔬 Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis | Science www.science.org/doi/10.1126/... @yiweichang.bsky.social www.yiweichanglab.org @jiwasa.bsky.social #virology #Influenza #Cryo-EM #StructuralBiology #RNA #polymerase
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Reposted by Sudipta Mondal
Scripps Research @scripps.edu · 23/04/2025
Scripps Research and @pittofficial.bsky.social capture the first cryo-EM & cryo-ET images of a virus infecting TB-causing Mycobacteria, revealing an unexpected infection mechanism that could inform phage therapies for drug-resistant TB, per @cellpress.bsky.social.
scripps.edu
The very first structural images of a tuberculosis-fighting virus
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Reposted by Sudipta Mondal
Ben Engel @cellarchlab.com · 18/04/2025
Some eye-catching #TeamTomo work here. Congrats to @kfreeman.bsky.social and all the authors! 🧪🧶🧬🔬
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Sudipta Mondal @sudipta-cryoet.bsky.social · 17/04/2025
Host invasion by a mycobacteriophage—visualized in action! 🦠✨ Thrilled to have contributed to this exciting work! Great collaboration with the amazing Krista @kfreeman.bsky.social & Graham Hatfull lab. Huge thanks to the Park lab for this fantastic opportunity 🙌 #CryoEM #CryoET #phage #mycobacteria
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Sudipta Mondal @sudipta-cryoet.bsky.social · 11/04/2025
Had an amazing week at the Gordon Research Conference on Biology of Mycobacteria! Great chats, exciting posters and the chance to meet both legends in the field and awesome new peers… #mycobacteria
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