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Slater Clay

@slaterc.bsky.social
368 followers 350 following 12 posts

Mucosal Immunology & Anti-Tumor Immunity Postdoc | Wendy Garrett Lab | Harvard School of Public Health

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Joe Longo @joelongo.bsky.social · 29/06/2026
The #LongoLab @roswellpark.bsky.social is seeking a highly motivated postdoc to join our growing team studying how metabolism regulates tumor growth and anti-tumor immunity. More information here: www.roswellpark.org/careers/post...
roswellpark.org
Postdoctoral Fellow in Cancer and Immunometabolism
A postdoctoral position is available in the laboratory of Dr. Joseph Longo in the Department of Immunology at Roswell Park Comprehensive Cancer Center. The Longo Lab studies how metabolism and nutriti...
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Reposted by Slater Clay
Andy Hogan @andyhogan82.bsky.social · 02/06/2026
🚨 New Publication Alert - out now in @science.org - We outline the environmental regulators of MAIT cells including the nutrients they need - with them coming into focus in cancer this is sure to be important - read it here doi.org/10.1126/scis...
doi.org
Environmental regulation of mucosal-associated invariant T cells: Adding food for thought
Nutrients are important environmental factors that affect the functional responses of MAIT cells to challenge.
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Slater Clay @slaterc.bsky.social · 27/05/2026
So good to see this finally out!
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Reposted by Slater Clay
Andy Hogan @andyhogan82.bsky.social · 29/04/2026
Delighted to share our latest paper out today - led by @ardeena-berisha.bsky.social - we show that we can boost the anti-cancer activity of human MAIT cells by getting them to use lactate & also directing them using bi-specific engagers as a proof of concept academic.oup.com/jimmunol/art...
academic.oup.com
Lactate conditioning reprograms mucosal-associated invariant T cell metabolism boosting effector function
Abstract. Mucosal-associated invariant T (MAIT) cells are unconventional T cells, which upon activation can display potent cytotoxic and cytokine-producing
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Reposted by Slater Clay
Waggoner Lab @labwaggoner.bsky.social · 05/12/2025
Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation www.science.org/doi/10.1126/... @science.org @thedohertyinst.bsky.social @hay-mish.bsky.social
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Slater Clay @slaterc.bsky.social · 02/11/2025
Excited to share a preprint from my postdoc @theGarrettLab- now on bioRxiv! Oral acetoacetate (AcAc) suppresses tumor growth by expanding and activating MAIT cells… and the mechanism was a surprise 🧵👇 (1/10) www.biorxiv.org/content/10.1...
biorxiv.org
Acetoacetate suppresses colon cancer via an MR1-MAIT axis
Colorectal cancer (CRC) is a leading cause of cancer mortality and additional preventative, and therapeutic strategies are urgently needed. Ketogenic diets have mixed effects on tumorigenesis and comp...
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