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Seth Ari Sim-Son Hoffman

@sethahoffmanmd.bsky.social
2.9K followers 952 following 79 posts

Instructor, Infectious disease doc/researcher @Stanford • Research to benefit the under-served #IDSky #GlobalHealth #PlanetaryHealth 🇺🇸=🇺🇦x🇲🇾 profiles.stanford.edu/seth-hoffman

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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 26/12/2025
Really pleased to finally get this published. Happy Holidays and Happy 2026! t.co/LxxOgKQXLP
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Stanford Center for Innovation in Global Health @stanfordcigh.bsky.social · 04/12/2025
Global Health Faculty Fellows Dr. Bonnie Maldonado and @sethahoffmanmd.bsky.social contributed to this timely report about aluminum salts in childhood vaccines, reviewing nearly a century of evidence about key safety concerns.
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Edward Nirenberg @enirenberg.bsky.social · 05/12/2025
Now we have a presentation from Griffin on aluminum adjuvants, which I'm sure will be a very fun experience from me. I will note that there is no inclusion of this on the latest agenda, though it was there in previous versions.
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Edward Nirenberg @enirenberg.bsky.social · 03/12/2025
#medsky #pedsky #idsky #immunosky #episky I collaborated with exceptionally talented people in infectious diseases to write this Special Article about aluminum salts in childhood vaccines. We review the evidence base for key safety concerns and offer guidance for communication with caregivers.
publications.aap.org
The Role and Safety of Aluminum Adjuvants in Childhood Vaccines
Aluminum salts have been used as adjuvants in vaccines for nearly a century, enhancing the immune response to purified antigens and ensuring durable protection against serious infectious diseases. Des...
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 17/09/2025
Luby Lab has 2 open postdoctoral positions, one focused on laboratory/measurement advances and a second focused on survey design and analysis. The full position details are here: hph.stanford.edu/careers lubylab.stanford.edu
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 17/09/2025
Luby Lab has 2 open postdoctoral positions, one focused on laboratory/measurement advances and a second focused on survey design and analysis. The full position details are here: hph.stanford.edu/careers lubylab.stanford.edu
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 13/06/2025
🎉🎉🎉
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 12/06/2025
🙏🙏🙏
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Edward Nirenberg @enirenberg.bsky.social · 12/06/2025
Brief 🧵 Hi, everyone. I know so many people have been affected by the funding cuts to science in horrific ways. Sanaria, the company I am consulting for, has produced unprecedented progress in a highly effective malaria vaccine and is in major financial jeopardy because of these cuts.
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 03/06/2025
Sanaria reports positive initial safety results for groundbreaking PfSPZ-LARC2 malaria vaccine 🎉🎉🎉 www.eurekalert.org/news-release... @malarianomore.org @lshtm-malaria.bsky.social @pathmalaria.bsky.social @malariaconsortium.bsky.social @gatesfoundation.bsky.social @stanfordcigh.bsky.social
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Stanford Center for Innovation in Global Health @stanfordcigh.bsky.social · 14/05/2025
Exciting to see the highly impactful work of Stanford's Luby Lab to address pollution from brick kilns featured in @science.org! #planetaryhealth
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 09/05/2025
#LubyLab! So proud of the vital work our lab does for humans and our planet @stanfordcigh.bsky.social @stanforddeptmed.bsky.social
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BK. Titanji @boghuma.bsky.social · 10/04/2025
Maybe it's just me but I feel very sad that the United States has a #measles tracker in 2025, when we have had a vaccine that is 97% effective for over 50 years. www.nbcnews.com/data-graphic...
nbcnews.com
Map: Track the spread of measles in the U.S.
More than 600 cases have been confirmed so far this year. NBC News is updating case totals twice every week.
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 31/03/2025
Absolutely fantastic, timely, and important conversation podcasts.apple.com/us/podcast/g...
podcasts.apple.com
Weaning off Foreign Aid with Catherine Kyobutungi
Podcast Episode · Global Health Unfiltered · 03/30/2025 · 1h 4m
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Max Bayer @maxbayer.bsky.social · 20/03/2025
An @endpts.com exclusive: the CDC's ACIP meeting has been rescheduled to mid-April. endpts.com/acip-meeting...
endpts.com
CDC vaccine meeting, delayed earlier this year, is rescheduled
A meeting of CDC vaccine advisors that’s been in limbo for almost a month is slated to take place around the middle of April, two sources familiar with the planning told Endpoints News.
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Stanford Center for Innovation in Global Health @stanfordcigh.bsky.social · 26/02/2025
“Measles is the most infectious virus we know. However, it’s a harbinger of low vaccination rates, and it is quite likely we will start seeing outbreaks of other diseases that are vaccine preventable as well as these vaccine rates decrease." www.cnn.com/2025/02/26/h...
cnn.com
Child in West Texas is first US measles death in a decade | CNN
The first measles death in the growing outbreak in West Texas was a school-aged child.
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Jason L. Schwartz @jasonlschwartz.bsky.social · 20/02/2025
If people are interested in learning about the ACIP and its decades of contributions to US vaccine policy successes, here’s a short 2014 piece I wrote in NEJM with Adel Mahmoud (timed with its 50th anniversary) www.nejm.org/doi/full/10....
nejm.org
A Half-Century of Prevention — The Advisory Committee on Immunization Practices | NEJM
In 1964, after a vaccination program against polio, diphtheria, tetanus, and pertussis began, the Advisory Committee on Immunization Practices was created to advise the U.S. government on vaccinati...
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Edward Nirenberg @enirenberg.bsky.social · 18/02/2025
There’s a lot of… discussion… right now about what’s going on with the US’s current flu season, which seems to be the worst it’s been in 15 years of recorded data. I’d like to clarify some things to help people understand:
cdc.gov
Weekly US Influenza Surveillance Report: Key Updates for Week 6, ending February 8, 2025
Influenza activity is increasing slightly among children but remains low nationally.
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Edward Nirenberg @enirenberg.bsky.social · 18/02/2025
I can't underscore this enough- Kennedy's word is worthless. He says whatever he needs to say to maximize the power he holds and he tells baldfaced lies without flinching (just look at his confirmation hearings). He actively ignores the evidence- it's been shown to him many times.
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Jeremy Berg @jeremymberg.bsky.social · 18/02/2025
ATTENTION If you are on a study section that was scheduled to meet, please post or DM me with information regarding: 1. The name of the study section 2. The scheduled date 3. Whether the meeting actually occurred THANK YOU
media.tenor.com
a man wearing a top hat and a purple jacket is asking for more .
ALT: a man wearing a top hat and a purple jacket is asking for more .
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 17/02/2025
😂….🥲…🫣…😭
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 14/02/2025
just missing the ALL CAPS...🫠
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Edward Nirenberg @enirenberg.bsky.social · 13/02/2025
#medsky#pedsky#idsky#immunosky 🧪 In the midst of all of the scary headlines recently, I thought I could take a moment to share a bit of good news: for the first time in history, a malaria vaccine with >90% efficacy seems to be within reach! Here’s why that’s a really big deal for EVERYONE 🧵
sanaria.com
A Single-Dose Breakthrough: PfSPZ-LARC Vaccines Offer Transformative Protection Against Malaria – Sanaria
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 12/02/2025
In light of all the negativity in the news, awesome to see SCRI and Sanaria's (sanaria.com) #malariavaccine work being highlighted! 😍 🦟🤺💉 www.news-medical.net/news/2025021...
news-medical.net
Groundbreaking malaria vaccine provides high-level protection with just one dose
Scientists at Sanaria and Seattle Children's Research Institute's Center for Global Infectious Disease Research (CGIDR) have unveiled a groundbreaking malaria vaccine, Sanaria® PfSPZ-LARC2 Vaccine, de...
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 05/02/2025
This is not ideal...
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Andrew M Leber @andrewleber.bsky.social · 29/01/2025
Louisiana folks - Sen. Cassidy may be wavering on RFKj. Cassidy's office number in DC is (202) 224-5824 if you want to let him know what you think about that nomination.
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 29/01/2025
How to: Place oneself on the causal pathway 🧐
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Edward Nirenberg @enirenberg.bsky.social · 29/01/2025
I commend Dr. Kennedy-Meltzer on the courage of sharing this with the public. I beseech people to see reason: there is no one more anti-qualified to serve as secretary of HHS. www.statnews.com/2025/01/28/k... www.documentcloud.org/documents/25...
statnews.com
Private emails show RFK Jr. making false claims about Covid-19 shots, linking vaccines to autism
Kennedy's niece, a NYC physician, shares private emails, says public needs to see what she calls her uncle’s misguided views and conspiracy theories.
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Madhu Pai, MD, PhD @madhupai.bsky.social · 22/01/2025
Just as WHO is under attack, Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring www.science.org/content/arti...
science.org
Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring
Researchers facing
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Madhu Pai, MD, PhD @madhupai.bsky.social · 22/01/2025
“Member states in each region of the world should step up and make sure WHO is sustainably financed” www.theguardian.com/commentisfre...
theguardian.com
Memo to President Trump: you are wrong to leave the World Health Organization. You should think again | Gordon Brown
Any funding disparities can be addressed, but another pandemic is coming – and we’ll need the WHO to help fight it, says former UK prime minister Gordon Brown
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Gregg Gonsalves @gregggonsalves.bsky.social · 22/01/2025
Are you a researcher in a “red” state? Time to call and keep calling every member of your Congressional delegation. Capitol switchboard: (202) 224-3121
media.tenor.com
a close up of a dragon 's head with fire coming out of it 's mouth .
ALT: a close up of a dragon 's head with fire coming out of it 's mouth .
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Dan Diamond @ddiamond.bsky.social · 22/01/2025
New: Trump officials have paused all external communications at health agencies like CDC, FDA, NIH. No health alerts and the famed MMWRs; no updates to key websites or social media posts. And no indication how long the pause will last. With @rachelroubein.bsky.social + Lena Sun.
washingtonpost.com
Trump officials pause health agencies’ communications, citing review
The agencies are charged with making decisions that touch the lives of every American and are the source of crucial information to health-care providers.
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BK. Titanji @boghuma.bsky.social · 21/01/2025
Now more than ever: Global health needs champions Science needs champions Public health needs champions. I will keep doing my part because it's the one thing I can control. Sharing fact-based information on science, health and global health threats.
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Rhys Parry @rhyshparry.bsky.social · 18/01/2025
Here we provide evidence of henipaviruses in North America with the discovery of Camp hill virus in the Northern Short-Tailed Shrew, Alabama. Early release article available from EID wwwnc.cdc.gov/eid/article/... #virology
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Eddie Holmes @eddieholmes.bsky.social · 17/01/2025
Worth remembering that the evidence tally for/against lab leak currently stands at none/lots
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Helen Branswell 🇨🇦 @helenbranswell.bsky.social · 16/01/2025
#USDA confirms 1 more #H5N1 #birdflu infected dairy herd in California. CA's total is up to 711 herds, though 128 of them have been released from quarantine. The national total is 928 herds in 16 states. www.cdfa.ca.gov/AHFSS/Animal...
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Kai Kupferschmidt @kakape.bsky.social · 14/01/2025
Not good news: @who.int just announced a new Marburg outbreak in Tanzania. “As of 11 January 2025, nine suspected cases were reported including eight deaths across two districts – Biharamulo and Muleba. … Results are pending official confirmation.” 🧪 #IDsky www.who.int/emergencies/...
who.int
Outbreak of suspected Marburg Virus Disease– United Republic of Tanzania
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Angie Rasmussen @angierasmussen.bsky.social · 14/01/2025
Really bad news. I hate it when Marburg shows up.
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Richard Corsi @corsiaq.bsky.social · 12/01/2025
That's good of ASHRAE. Given that what has happened in Paradise, Lanai, and now Los Angeles will be played out over and over and over again, I would love for ASHRAE to make 44-2024 & future iterations available indefinitely as a contribution to the many who will be effected in the future.
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Edward Nirenberg @enirenberg.bsky.social · 09/01/2025
Tour de force work from @kcklatt.bsky.social concerning water fluoridation history, opposition to fluoridation, and the health consequences open.substack.com/pub/kcklatt/...
open.substack.com
Swimming in a (Fluoridated) Sea of Inadequate Data
On the history of fluoride and the new NTP Fluoride and IQ Meta-analysis
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 09/01/2025
@kcklatt.bsky.social heyyy…I got my first and only cavity at Cornell too! 🤔🧐
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 08/01/2025
😂😂😂
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Liz Highleyman @lizhighleyman.bsky.social · 07/01/2025
www.theguardian.com/world/2025/j...
theguardian.com
Dozens dead as strong 6.8-magnitude earthquake in Tibet felt as far as Nepal and India
Quake damaged buildings in Shigatse and could be felt hundreds of kilometres away in Nepal and the Indian state of Bihar
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 05/01/2025
“Unexpected”…
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Edward Nirenberg @enirenberg.bsky.social · 20/12/2024
There's a really interesting new paper out in Science for people who care about immunity to flu (which should be everyone because flu is a VERY big problem): www.science.org/doi/10.1126/... Here's my thread explaining this work🧵
science.org
Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses
The seasonal influenza vaccine contains strains of viruses from distinct subtypes that are grown independently and then combined. However, most individuals exhibit a more robust response to one of the...
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 03/01/2025
👏👏👏 @stanforddeptmed.bsky.social @stanfordcigh.bsky.social
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BK. Titanji @boghuma.bsky.social · 01/01/2025
Great to see published in @nejm.org the case report on the severe case of H5N1 in a Canadian teenager. this is an opportunity to learn but also a reminder of how severe these infections can be. A brief summary 🧵 #IDSky #MedSky 🧪 www.nejm.org/doi/full/10....
nejm.org
Critical Illness in an Adolescent with Influenza A(H5N1) Virus Infection | NEJM
Influenza A(H5N1) viruses are an emerging zoonotic threat and have spread widely throughout birds in North America. Recently, influenza A(H5N1) infection led to serious illness in a teenager in Canada...
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Richard Corsi @corsiaq.bsky.social · 01/01/2025
A professional highlight of 2024 was completion of a National Academies Consensus Study Report on Health Risks of Indoor Exposure to Fine Particulate Matter & Practical Mitigation Solutions. Product of 2 yrs of hard work by an extraordinary committee. Five overarching conclusions provided in thread.
Image shows the cover of a National Academies consensus study report entitled "Health Risks of Indoor Exposure to Fine Particulate Matter and Practical Mitigation Solutions."  The cover is deep purple and shows light coming through a window with what appears to be a lot of particles in the air.
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BK. Titanji @boghuma.bsky.social · 01/01/2025
1/ 🧵Breaking down the latest findings on Highly Pathogenic Avian Influenza A(H5N1) in the U.S. (March–Oct 2024). This NEJM case series is timely and a key resource for understanding recent outbreaks among human. 🧪 #MedSky #IDSky www.nejm.org/doi/full/10....
nejm.org
Highly Pathogenic Avian Influenza A(H5N1) Virus Infections in Humans | NEJM
Highly pathogenic avian influenza A(H5N1) viruses have caused widespread infections in dairy cows and poultry in the United States, with sporadic human cases. We describe characteristics of human A...
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Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 30/12/2024
The urgent care system @abraarkaran.bsky.social and I work at just notified providers that all our pharmacies are currently out of Tamiflu due to very high #InfluenzaA positivity…🤧🙊🙉🙈😱 #MaskUp and wash those paws! (for #norovirus too…👻)
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