Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 26/12/2025Really pleased to finally get this published. Happy Holidays and Happy 2026! t.co/LxxOgKQXLP 130
Reposted by Seth Ari Sim-Son HoffmanStanford Center for Innovation in Global Health @stanfordcigh.bsky.social · 04/12/2025Global Health Faculty Fellows Dr. Bonnie Maldonado and @sethahoffmanmd.bsky.social contributed to this timely report about aluminum salts in childhood vaccines, reviewing nearly a century of evidence about key safety concerns. 0114
Reposted by Seth Ari Sim-Son HoffmanEdward Nirenberg @enirenberg.bsky.social · 05/12/2025Now we have a presentation from Griffin on aluminum adjuvants, which I'm sure will be a very fun experience from me. I will note that there is no inclusion of this on the latest agenda, though it was there in previous versions. 495
Reposted by Seth Ari Sim-Son HoffmanEdward Nirenberg @enirenberg.bsky.social · 03/12/2025#medsky #pedsky #idsky #immunosky #episky I collaborated with exceptionally talented people in infectious diseases to write this Special Article about aluminum salts in childhood vaccines. We review the evidence base for key safety concerns and offer guidance for communication with caregivers.publications.aap.orgThe Role and Safety of Aluminum Adjuvants in Childhood VaccinesAluminum salts have been used as adjuvants in vaccines for nearly a century, enhancing the immune response to purified antigens and ensuring durable protection against serious infectious diseases. Des... 717270
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 17/09/2025Luby Lab has 2 open postdoctoral positions, one focused on laboratory/measurement advances and a second focused on survey design and analysis. The full position details are here: hph.stanford.edu/careers lubylab.stanford.edu 010
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 17/09/2025Luby Lab has 2 open postdoctoral positions, one focused on laboratory/measurement advances and a second focused on survey design and analysis. The full position details are here: hph.stanford.edu/careers lubylab.stanford.edu 010
Reposted by Seth Ari Sim-Son HoffmanEdward Nirenberg @enirenberg.bsky.social · 12/06/2025Brief 🧵 Hi, everyone. I know so many people have been affected by the funding cuts to science in horrific ways. Sanaria, the company I am consulting for, has produced unprecedented progress in a highly effective malaria vaccine and is in major financial jeopardy because of these cuts. 39850
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 03/06/2025Sanaria reports positive initial safety results for groundbreaking PfSPZ-LARC2 malaria vaccine 🎉🎉🎉 www.eurekalert.org/news-release... @malarianomore.org @lshtm-malaria.bsky.social @pathmalaria.bsky.social @malariaconsortium.bsky.social @gatesfoundation.bsky.social @stanfordcigh.bsky.social 095
Reposted by Seth Ari Sim-Son HoffmanStanford Center for Innovation in Global Health @stanfordcigh.bsky.social · 14/05/2025Exciting to see the highly impactful work of Stanford's Luby Lab to address pollution from brick kilns featured in @science.org! #planetaryhealth 011
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 09/05/2025#LubyLab! So proud of the vital work our lab does for humans and our planet @stanfordcigh.bsky.social @stanforddeptmed.bsky.social 042
Reposted by Seth Ari Sim-Son HoffmanBK. Titanji @boghuma.bsky.social · 10/04/2025Maybe it's just me but I feel very sad that the United States has a #measles tracker in 2025, when we have had a vaccine that is 97% effective for over 50 years. www.nbcnews.com/data-graphic...nbcnews.comMap: Track the spread of measles in the U.S.More than 600 cases have been confirmed so far this year. NBC News is updating case totals twice every week. 1324162
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 31/03/2025Absolutely fantastic, timely, and important conversation podcasts.apple.com/us/podcast/g...podcasts.apple.comWeaning off Foreign Aid with Catherine KyobutungiPodcast Episode · Global Health Unfiltered · 03/30/2025 · 1h 4m 000
Reposted by Seth Ari Sim-Son HoffmanMax Bayer @maxbayer.bsky.social · 20/03/2025An @endpts.com exclusive: the CDC's ACIP meeting has been rescheduled to mid-April. endpts.com/acip-meeting...endpts.comCDC vaccine meeting, delayed earlier this year, is rescheduledA meeting of CDC vaccine advisors that’s been in limbo for almost a month is slated to take place around the middle of April, two sources familiar with the planning told Endpoints News. 145
Reposted by Seth Ari Sim-Son HoffmanStanford Center for Innovation in Global Health @stanfordcigh.bsky.social · 26/02/2025“Measles is the most infectious virus we know. However, it’s a harbinger of low vaccination rates, and it is quite likely we will start seeing outbreaks of other diseases that are vaccine preventable as well as these vaccine rates decrease." www.cnn.com/2025/02/26/h...cnn.comChild in West Texas is first US measles death in a decade | CNNThe first measles death in the growing outbreak in West Texas was a school-aged child. 121
Reposted by Seth Ari Sim-Son HoffmanJason L. Schwartz @jasonlschwartz.bsky.social · 20/02/2025If people are interested in learning about the ACIP and its decades of contributions to US vaccine policy successes, here’s a short 2014 piece I wrote in NEJM with Adel Mahmoud (timed with its 50th anniversary) www.nejm.org/doi/full/10....nejm.orgA Half-Century of Prevention — The Advisory Committee on Immunization Practices | NEJMIn 1964, after a vaccination program against polio, diphtheria, tetanus, and pertussis began, the Advisory Committee on Immunization Practices was created to advise the U.S. government on vaccinati... 2216129
Reposted by Seth Ari Sim-Son HoffmanEdward Nirenberg @enirenberg.bsky.social · 18/02/2025There’s a lot of… discussion… right now about what’s going on with the US’s current flu season, which seems to be the worst it’s been in 15 years of recorded data. I’d like to clarify some things to help people understand:cdc.govWeekly US Influenza Surveillance Report: Key Updates for Week 6, ending February 8, 2025Influenza activity is increasing slightly among children but remains low nationally. 113143
Reposted by Seth Ari Sim-Son HoffmanEdward Nirenberg @enirenberg.bsky.social · 18/02/2025I can't underscore this enough- Kennedy's word is worthless. He says whatever he needs to say to maximize the power he holds and he tells baldfaced lies without flinching (just look at his confirmation hearings). He actively ignores the evidence- it's been shown to him many times. 613422
Reposted by Seth Ari Sim-Son HoffmanJeremy Berg @jeremymberg.bsky.social · 18/02/2025ATTENTION If you are on a study section that was scheduled to meet, please post or DM me with information regarding: 1. The name of the study section 2. The scheduled date 3. Whether the meeting actually occurred THANK YOUmedia.tenor.coma man wearing a top hat and a purple jacket is asking for more .ALT: a man wearing a top hat and a purple jacket is asking for more . 38104107
Reposted by Seth Ari Sim-Son HoffmanEdward Nirenberg @enirenberg.bsky.social · 13/02/2025#medsky#pedsky#idsky#immunosky 🧪 In the midst of all of the scary headlines recently, I thought I could take a moment to share a bit of good news: for the first time in history, a malaria vaccine with >90% efficacy seems to be within reach! Here’s why that’s a really big deal for EVERYONE 🧵sanaria.comA Single-Dose Breakthrough: PfSPZ-LARC Vaccines Offer Transformative Protection Against Malaria – Sanaria 427153792802
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 12/02/2025In light of all the negativity in the news, awesome to see SCRI and Sanaria's (sanaria.com) #malariavaccine work being highlighted! 😍 🦟🤺💉 www.news-medical.net/news/2025021...news-medical.netGroundbreaking malaria vaccine provides high-level protection with just one doseScientists at Sanaria and Seattle Children's Research Institute's Center for Global Infectious Disease Research (CGIDR) have unveiled a groundbreaking malaria vaccine, Sanaria® PfSPZ-LARC2 Vaccine, de... 1103
Reposted by Seth Ari Sim-Son HoffmanAndrew M Leber @andrewleber.bsky.social · 29/01/2025Louisiana folks - Sen. Cassidy may be wavering on RFKj. Cassidy's office number in DC is (202) 224-5824 if you want to let him know what you think about that nomination. 6356227
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 29/01/2025How to: Place oneself on the causal pathway 🧐 120
Reposted by Seth Ari Sim-Son HoffmanEdward Nirenberg @enirenberg.bsky.social · 29/01/2025I commend Dr. Kennedy-Meltzer on the courage of sharing this with the public. I beseech people to see reason: there is no one more anti-qualified to serve as secretary of HHS. www.statnews.com/2025/01/28/k... www.documentcloud.org/documents/25...statnews.comPrivate emails show RFK Jr. making false claims about Covid-19 shots, linking vaccines to autismKennedy's niece, a NYC physician, shares private emails, says public needs to see what she calls her uncle’s misguided views and conspiracy theories. 9251100
Reposted by Seth Ari Sim-Son HoffmanMadhu Pai, MD, PhD @madhupai.bsky.social · 22/01/2025Just as WHO is under attack, Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring www.science.org/content/arti...science.orgTrump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiringResearchers facing 15033
Reposted by Seth Ari Sim-Son HoffmanMadhu Pai, MD, PhD @madhupai.bsky.social · 22/01/2025“Member states in each region of the world should step up and make sure WHO is sustainably financed” www.theguardian.com/commentisfre...theguardian.comMemo to President Trump: you are wrong to leave the World Health Organization. You should think again | Gordon BrownAny funding disparities can be addressed, but another pandemic is coming – and we’ll need the WHO to help fight it, says former UK prime minister Gordon Brown 04112
Reposted by Seth Ari Sim-Son HoffmanGregg Gonsalves @gregggonsalves.bsky.social · 22/01/2025Are you a researcher in a “red” state? Time to call and keep calling every member of your Congressional delegation. Capitol switchboard: (202) 224-3121media.tenor.coma close up of a dragon 's head with fire coming out of it 's mouth .ALT: a close up of a dragon 's head with fire coming out of it 's mouth . 29434
Reposted by Seth Ari Sim-Son HoffmanDan Diamond @ddiamond.bsky.social · 22/01/2025New: Trump officials have paused all external communications at health agencies like CDC, FDA, NIH. No health alerts and the famed MMWRs; no updates to key websites or social media posts. And no indication how long the pause will last. With @rachelroubein.bsky.social + Lena Sun.washingtonpost.comTrump officials pause health agencies’ communications, citing reviewThe agencies are charged with making decisions that touch the lives of every American and are the source of crucial information to health-care providers. 48543752976
Reposted by Seth Ari Sim-Son HoffmanBK. Titanji @boghuma.bsky.social · 21/01/2025Now more than ever: Global health needs champions Science needs champions Public health needs champions. I will keep doing my part because it's the one thing I can control. Sharing fact-based information on science, health and global health threats. 617832
Reposted by Seth Ari Sim-Son HoffmanRhys Parry @rhyshparry.bsky.social · 18/01/2025Here we provide evidence of henipaviruses in North America with the discovery of Camp hill virus in the Northern Short-Tailed Shrew, Alabama. Early release article available from EID wwwnc.cdc.gov/eid/article/... #virology 17229
Reposted by Seth Ari Sim-Son HoffmanEddie Holmes @eddieholmes.bsky.social · 17/01/2025Worth remembering that the evidence tally for/against lab leak currently stands at none/lots 24310
Reposted by Seth Ari Sim-Son HoffmanHelen Branswell 🇨🇦 @helenbranswell.bsky.social · 16/01/2025#USDA confirms 1 more #H5N1 #birdflu infected dairy herd in California. CA's total is up to 711 herds, though 128 of them have been released from quarantine. The national total is 928 herds in 16 states. www.cdfa.ca.gov/AHFSS/Animal... 06312
Reposted by Seth Ari Sim-Son HoffmanKai Kupferschmidt @kakape.bsky.social · 14/01/2025Not good news: @who.int just announced a new Marburg outbreak in Tanzania. “As of 11 January 2025, nine suspected cases were reported including eight deaths across two districts – Biharamulo and Muleba. … Results are pending official confirmation.” 🧪 #IDsky www.who.int/emergencies/...who.intOutbreak of suspected Marburg Virus Disease– United Republic of Tanzania 315472
Reposted by Seth Ari Sim-Son HoffmanAngie Rasmussen @angierasmussen.bsky.social · 14/01/2025Really bad news. I hate it when Marburg shows up. 59625
Reposted by Seth Ari Sim-Son HoffmanRichard Corsi @corsiaq.bsky.social · 12/01/2025That's good of ASHRAE. Given that what has happened in Paradise, Lanai, and now Los Angeles will be played out over and over and over again, I would love for ASHRAE to make 44-2024 & future iterations available indefinitely as a contribution to the many who will be effected in the future. 13916
Reposted by Seth Ari Sim-Son HoffmanEdward Nirenberg @enirenberg.bsky.social · 09/01/2025Tour de force work from @kcklatt.bsky.social concerning water fluoridation history, opposition to fluoridation, and the health consequences open.substack.com/pub/kcklatt/...open.substack.comSwimming in a (Fluoridated) Sea of Inadequate DataOn the history of fluoride and the new NTP Fluoride and IQ Meta-analysis 45414
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 09/01/2025@kcklatt.bsky.social heyyy…I got my first and only cavity at Cornell too! 🤔🧐 110
Reposted by Seth Ari Sim-Son HoffmanLiz Highleyman @lizhighleyman.bsky.social · 07/01/2025www.theguardian.com/world/2025/j...theguardian.comDozens dead as strong 6.8-magnitude earthquake in Tibet felt as far as Nepal and IndiaQuake damaged buildings in Shigatse and could be felt hundreds of kilometres away in Nepal and the Indian state of Bihar 011
Reposted by Seth Ari Sim-Son HoffmanEdward Nirenberg @enirenberg.bsky.social · 20/12/2024There's a really interesting new paper out in Science for people who care about immunity to flu (which should be everyone because flu is a VERY big problem): www.science.org/doi/10.1126/... Here's my thread explaining this work🧵science.orgCoupling antigens from multiple subtypes of influenza can broaden antibody and T cell responsesThe seasonal influenza vaccine contains strains of viruses from distinct subtypes that are grown independently and then combined. However, most individuals exhibit a more robust response to one of the... 1023670
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 03/01/2025👏👏👏 @stanforddeptmed.bsky.social @stanfordcigh.bsky.social 031
Reposted by Seth Ari Sim-Son HoffmanBK. Titanji @boghuma.bsky.social · 01/01/2025Great to see published in @nejm.org the case report on the severe case of H5N1 in a Canadian teenager. this is an opportunity to learn but also a reminder of how severe these infections can be. A brief summary 🧵 #IDSky #MedSky 🧪 www.nejm.org/doi/full/10....nejm.orgCritical Illness in an Adolescent with Influenza A(H5N1) Virus Infection | NEJMInfluenza A(H5N1) viruses are an emerging zoonotic threat and have spread widely throughout birds in North America. Recently, influenza A(H5N1) infection led to serious illness in a teenager in Canada... 26614
Reposted by Seth Ari Sim-Son HoffmanRichard Corsi @corsiaq.bsky.social · 01/01/2025A professional highlight of 2024 was completion of a National Academies Consensus Study Report on Health Risks of Indoor Exposure to Fine Particulate Matter & Practical Mitigation Solutions. Product of 2 yrs of hard work by an extraordinary committee. Five overarching conclusions provided in thread. 2356
Reposted by Seth Ari Sim-Son HoffmanBK. Titanji @boghuma.bsky.social · 01/01/20251/ 🧵Breaking down the latest findings on Highly Pathogenic Avian Influenza A(H5N1) in the U.S. (March–Oct 2024). This NEJM case series is timely and a key resource for understanding recent outbreaks among human. 🧪 #MedSky #IDSky www.nejm.org/doi/full/10....nejm.orgHighly Pathogenic Avian Influenza A(H5N1) Virus Infections in Humans | NEJMHighly pathogenic avian influenza A(H5N1) viruses have caused widespread infections in dairy cows and poultry in the United States, with sporadic human cases. We describe characteristics of human A... 78831
Seth Ari Sim-Son Hoffman @sethahoffmanmd.bsky.social · 30/12/2024The urgent care system @abraarkaran.bsky.social and I work at just notified providers that all our pharmacies are currently out of Tamiflu due to very high #InfluenzaA positivity…🤧🙊🙉🙈😱 #MaskUp and wash those paws! (for #norovirus too…👻) 030