Will need to dig into this, but I can say I've seen some significant hits in GWAS for some of these conditions in non-coding regions, where things like transcription interference makes sense.
Here's the study this article was describing:
link.springer.com/article/10.1...
#MedSky
link.springer.com
Beyond genes: EpiSwitch® and Orion platform-powered 3D genome architecture biomarkers reveal shared biology across ME/CFS, long COVID, PTSD, rheumatoid arthritis, and multiple sclerosis - Journal of T...
Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Long COVID (LC19), post-traumatic stress disorder (PTSD), rheumatoid arthritis (RA), and multiple sclerosis (MS) are clinically ...
