Sébastien Poulin @sebpoule.bsky.social · 23/09/2026Great, but good luck trying that in Quebec, Canada, anywhere except Montreal 🤪 (live in suburbs) 020
Sébastien Poulin @sebpoule.bsky.social · 23/09/20262026 Hyundai IONIQ 5 Preferred Long Range AWD with Ultimate Package White matte (and same thing for my wife lol, we call them our “twins”) 140
Sébastien Poulin @sebpoule.bsky.social · 22/09/2026On this day, at the age of 42yo, Sept 22 2026, my last gas⛽️ 🚗 refill ever. Moving to electric car. Feels good. 5200
Sébastien Poulin @sebpoule.bsky.social · 20/09/2026static.klipy.comMan Making It Rain with MoneyALT: Man Making It Rain with Money 010
Sébastien Poulin @sebpoule.bsky.social · 20/09/2026Exactly. And as soon as it’s available, people will start to use it for whatever reasons (99% not good ones). That’s why I’m against it 100% 110
Sébastien Poulin @sebpoule.bsky.social · 20/09/2026Pro tip; Stop using “reply all” email to confirm an abstract review if you didn’t change anything. 100
Reposted by Sébastien PoulinIlan Schwartz @germhuntermd.bsky.social · 17/09/2026Less is more, ortho-ID edition Another game changer in ortho ID from the group that brought you OVIVA Pts with ortho infections who underwent curative surgery (no DAIR) with local implantation of abx were randomized to <=7d vs >=4w ABx No Dif in 12 mo relapse www.nejm.org/doi/full/10.... #IDSky 23217
Sébastien Poulin @sebpoule.bsky.social · 13/09/2026oh wow, hard to find indeed haha thank youstatic.klipy.comKen Jeong (Ben Chang) Says 'So Tiny'ALT: Ken Jeong (Ben Chang) Says 'So Tiny' 110
Sébastien Poulin @sebpoule.bsky.social · 13/09/2026Why no pdf ?static.klipy.comConfused White Cat Asks WhyALT: Confused White Cat Asks Why 301
Reposted by Sébastien PoulinAntibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 09/09/2026🔥🔥Back online🔥🔥 IDSA/ESCMID 2026 Guidelines on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children Part-1 #idsky www.idsociety.org/practice-gui... 0199
Sébastien Poulin @sebpoule.bsky.social · 08/09/2026static.klipy.comRon Burgundy Say Whaaat MemeALT: Ron Burgundy Say Whaaat Meme 110
Sébastien Poulin @sebpoule.bsky.social · 02/09/2026Watching a @wrexhamafc.co.uk 3-0 win against Millwall (between cases at the 🏥) Go Reds Go !!! cc @josephmarcusid.medsky.social 110
Reposted by Sébastien PoulinJonathan Ryder, MD @jonathanrydermd.bsky.social · 29/08/2026POET II RCT is out now in @nejm.org, assessing antibiotic duration in endocarditis! "Response-tailored" vs standard durations in Staph, Strep & Enterococci n=502 Response tailored with 13d less antibiotics, similar composite safety but higher relapse #IDSky www.nejm.org/doi/abs/10.1... 3249
Sébastien Poulin @sebpoule.bsky.social · 24/08/2026static.klipy.comTabarnak Patrick RoyALT: Tabarnak Patrick Roy 110
Reposted by Sébastien PoulinIDSA @idsainfo.bsky.social · 22/08/2026Meet the newest voices behind Let’s Talk ID! ID physicians @kcawcutt.bsky.social and @cortes-penfield.bsky.social join the podcast as co-hosts for episodes focused on research published in IDSA journals. (1/2) 2105
Reposted by Sébastien PoulinClinical Infectious Diseases @cidjournal.bsky.social · 18/08/2026HRA for you! HRA for you! HRA … not for you? ✅ Just Accepted ⭐ Editor's Choice 🔗 bit.ly/4wDbYls 032
Sébastien Poulin @sebpoule.bsky.social · 13/08/2026Have you ever seen a case of MRSL? Methicillin-Resistant Staphylococcus lugdunensis #IDsky n=1 yesterday for me 😵💫 130
Reposted by Sébastien PoulinAntibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 30/07/2026🔥🔥IDSA AMR Guidance 2026🔥🔥 🔺Notable Updates from the 2024 IDSA AMR Guidance Document 🔺Meropenem dosing update: individualized dosing approach (1–2 g IV q8h) with higher doses considered in selected clinical scenarios. #idsky www.idsociety.org/practice-gui... 1166
Sébastien Poulin @sebpoule.bsky.social · 16/07/2026A dream come true Visit of Wrexham 🏴 from 🇨🇦 @wrexhamafc.co.uk @vancityreynolds.bsky.social 140
Sébastien Poulin @sebpoule.bsky.social · 14/07/2026Source control > antibiotics since 1270 #NorthWalesTours #IDsky 050
Sébastien Poulin @sebpoule.bsky.social · 08/07/2026p.s. Two 🇨🇦 @wrexhamafc.co.uk fans in the family 000
Sébastien Poulin @sebpoule.bsky.social · 19/06/2026Well, it finally happened. My first awkward Zoom moment. I was watching a pan-🇨🇦 post EASL meeting presentation (by CASL). I forgot to close my camera. I ended up bare chest while preparing a workout at home… in front of the « crowd » . 🤪😅🤦♂️🤷♂️ 030
Sébastien Poulin @sebpoule.bsky.social · 17/06/2026and Benzylpenicillin versus flucloxacillin or cloxacillin for the treatment of penicillin-susceptible Staphylococcus aureus bacteraemia (SNAP): an international, multicentre, open-label, non-inferiority randomised controlled trial @thelancet.com #IDsky www.sciencedirect.com/science/arti...sciencedirect.com 082
Reposted by Sébastien PoulinAntibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 17/06/2026🔥Just published 🔥NEJM SNAP RCT In patients with MSSA bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality and was associated with a lower incidence of acute kidney injury. #idsky www.nejm.org/doi/full/10....nejm.orgCefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia | NEJMStaphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin should be preferred for the treatment of methicillin-susceptible S. aureus ... 03115
Reposted by Sébastien PoulinThe Journal of Infectious Diseases @jidjournal.bsky.social · 10/06/2026Concomitant liver steatosis in chronic HBV infection is linked to a distinct cytokine profile and reduced viral load ✅ Just Accepted 🔗 bit.ly/4ejsct3 132
Sébastien Poulin @sebpoule.bsky.social · 09/06/2026This was an incredible collaboration between Johns Hopkins Division of Infectious Diseases, University of Toronto, NIH, and Aarhus University. Thanks to the Hopkins CFAR, the Ontario HIV Treatment Network and the W.W. Smith Charitable Trust for funding this study. 100
Sébastien Poulin @sebpoule.bsky.social · 09/06/2026You can find the paper here rdcu.be/fm8lU We hope this study will improve the care of people with HIV with detectable viremia on ART and provide a new tool to study HIV persistence. 100
Sébastien Poulin @sebpoule.bsky.social · 09/06/2026➡️We observed a progressive increase in 5'L-defective RNA in plasma from 1 month on ART (~1%) to long-term ART (~95%), suggesting differential selective pressure for 5'L-defective proviruses. 100
Sébastien Poulin @sebpoule.bsky.social · 09/06/2026➡️We developed a digital PCR assay allowing to easily Capture 5'Leader Anomalies Without Sequencing (🦀CLAWS🦀). CLAWS is a "drop-off" dPCR assay that can distinguish intact from mutated or deleted Major Splicing Donor (MSD) sequences, where 5'Leader defects converge. 100
Sébastien Poulin @sebpoule.bsky.social · 09/06/2026➡️NSV during long-term ART is most likely caused by 5'Leader defective virus released from infected clones, extending previous work from our group and others. 100
Sébastien Poulin @sebpoule.bsky.social · 09/06/2026We studied ~50 PWH on ART with detectable viremia despite no drug resistance and optimal adherence to investigate the frequency of defective proviruses contributing to HIV in plasma. Three take home messages: 100
Sébastien Poulin @sebpoule.bsky.social · 09/06/2026Important #HIV work by @frsimonetti.bsky.social and team. Here's a post by Dr Simonetti on LinkedIn👇 #IDsky ________________________________________ 🦀Time to celebrate🦀. Our study on #HIV non-suppressible viremia despite effective ART has been published in Nature Portfolio (Nat Comm). 120
Sébastien Poulin @sebpoule.bsky.social · 07/06/2026Cancelled; Studies of Oral Weekly Lepetegravir (Formerly GS-1720) and Lenacapavir Pacfosacil (Formerly GS-4182); WONDERS-1 and WONDERS-2 ⬇️CD4 I won’t lie; I completely missed that. #IDsky #HIVsky www.fiercebiotech.com/biotech/gile...fiercebiotech.comGilead cancels midstage HIV trial as FDA’s clinical hold remains intactAfter the FDA placed two of its next-gen HIV drugs on clinical hold last June, Gilead Sciences has now terminated one of the affected trials. | After the FDA placed two of its next-gen HIV drugs on cl... 110
Sébastien Poulin @sebpoule.bsky.social · 29/05/2026#EASL2026 «For the very first time in history, you saw a phase 3 trial with the endpoint S antigen (HBsAg) loss» -Dr @heinerwedemeyer.bsky.social about HBV B-Well phase 3 trials #IDskystatic.klipy.comLance Geiger: That Is History!ALT: Lance Geiger: That Is History! 010
Sébastien Poulin @sebpoule.bsky.social · 28/05/2026HBV Functional cure with Bepirovirsen B-Well 1 and B-Well 2 phase 3 studies ➡️ 24 weeks of Bepi s/c q1 week (all on NUCs) ~19% if qHBsAg <3000 ~26% if qHBsAg <1000 #EASL2026 #IDskynejm.orgPhase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection | NEJMTreatment with bepirovirsen, an antisense oligonucleotide targeting hepatitis B virus (HBV) transcripts, has the potential to result in a functional cure, defined by at least 24 weeks of a sustaine... 031
Reposted by Sébastien PoulinAntibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 27/05/2026🆕💥🔴Don’t Drop the B: Risk of Hepatitis B Virus Infection and Reactivation in the Era of Tenofovir-Sparing Regimens for Treatment and Prevention of HIV #idsky academic.oup.com/cid/article-...academic.oup.comDon’t Drop the B: Risk of Hepatitis B Virus Infection and Reactivation in the Era of Tenofovir-Sparing Regimens for Treatment and Prevention of HIVAbstracts. Tenofovir-sparing antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) are increasingly used. 031
Sébastien Poulin @sebpoule.bsky.social · 27/05/2026Top 20 Greatest Hits in HIV Medicine; Thank you Dr @paulsaxmd.bsky.social for your great Montreal 🇨🇦 presentation (special bonus; picture of young Dr Sax and colleagues) 040
Sébastien Poulin @sebpoule.bsky.social · 03/05/2026media.tenor.coma picture of a mountain with the words coucou written on itALT: a picture of a mountain with the words coucou written on it 000
Sébastien Poulin @sebpoule.bsky.social · 30/04/2026Long time no see #IDsky Petechial hemorrhage in the palpebral conjunctiva of the lower eyelid … ❤️🩹Endocarditis (shared with patient consent) 071
Sébastien Poulin @sebpoule.bsky.social · 25/04/2026and don’t forget the nurses « 🤩 faces » that you get with Cefazolin q8h instead of Cloxa q4h 😉😅😉media.tenor.coma man says " it 's definitely worth it " in front of a gaming chairALT: a man says " it 's definitely worth it " in front of a gaming chair 161
Sébastien Poulin @sebpoule.bsky.social · 25/04/2026I believe you. It’s possible. But in my own 11 y of practice, I have seen many AKI requiring management with IV Cloxacillin. Same for my colleagues. (But we should use RCT results instead of our experience) p.s. I’m pretty sure in 🇨🇦 the $ favors Cefazolin when we include nurse / pharmacy time etc 121