iiinova — where your digital self keeps evolving

Sean Escola @seanescola.bsky.social · 25/08/2026

If insights from neuroscience can improve AI – e.g., by achieving low-power computing, continual learning, or enhanced cognition – the capital unlocked from the AI industry would drive clinical and scientific breakthroughs. I discuss this funding landscape here: www.youtube.com/watch?v=sSPd...

youtube.com

Sean Escola | Funding Brain Science @ Vision Weekend UK 2026

YouTube video by Foresight Institute

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Sean Escola @seanescola.bsky.social · 17/07/2026

Behavior-trained AI captures what we do but not the mental process behind it. @patrickmineault.bsky.social & I call that gap cognitive dark matter & think it explains a lot about where today's models could be improved. Enjoyed this chat with Jan Witkowski at CSHL. www.youtube.com/watch?v=s4t6...

youtube.com

Interview with: Sean Escola

YouTube video by CSHL Leading Strand

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Sean Escola @seanescola.bsky.social · 08/07/2026

AI models are trained on the outputs of human cognition, like behavior, but miss the underlying processes. It was great chatting about this “cognitive dark matter” with Annelies Gamble and how it could be key to improving the cognitive capabilities of AI. www.mixtureofexperts.co/p/the-though...

mixtureofexperts.co

The thoughts that never become behavior

A conversation with Sean Escola, Dan Wetmore, and Tom Griffiths

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Sean Escola @seanescola.bsky.social · 30/06/2026

Nobody spells it out like @kordinglab.bsky.social. In this latest @juanbenetpodcast.bsky.social episode, Konrad discusses why we need “compilers” to translate molecularly annotated connectomes into neural dynamics – generating data we could use to build better AI. www.youtube.com/watch?v=FHQf...

youtube.com

The Power of a Single Neuron and a Path to Simulating the Brain | Dr. Konrad Kording

YouTube video by Juan Benet Podcast

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Sean Escola @seanescola.bsky.social · 15/06/2026

What if we could redesign AI to mirror biology’s efficiency? Reardon & the Flourish team are exploring exactly that. By mapping neural connections in the human brain, they aim to develop biology-inspired AI that is radically more energy-efficient. Read here: www.wired.com/story/jeff-b...

wired.com

Jeff Bezos Is Funding a Wild Hunt for the Brain’s ‘Core Algorithm’

With $500 million in funding and a reported $2.5 billion valuation, Flourish wants to reinvent AI by putting real neurons under the microscope.

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Sean Escola @seanescola.bsky.social · 11/06/2026

Humans already alter their own brain states — coffee boosts focus and alcohol relaxes. Neurotech could deliver the same effects with precision and without the systemic risks. Read about how neurotech can expand from purely clinical to consumer use ⬇️ zenodo.org/records/2011...

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juanbenet @juanbenet.bsky.social · 11/05/2026

Ep 2 of my new podcast is out today! My guest is Ben Rapoport, co-founder and CSO of @precisionneuro.bsky.social, which has built Layer 7, an innovative BCI that reads from the cortex surface without penetrating it. Hope you enjoy the conversation! www.youtube.com/watch?v=a8-9...

youtube.com

Ben Rapoport — Treating Paralysis and Digitizing Brain Data

YouTube video by Juan Benet Podcast

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juanbenet @juanbenet.bsky.social · 27/05/2026

Ep 3 of the podcast is out. My guest: @jacquescarolan.bsky.social, a founding Program Director at @aria-research.bsky.social. He directs two neurotech programs developing tools and systems to interface, at scale, with the human brain. Hope you enjoy! youtu.be/RAmigpsKCQY

youtu.be

Jacques Carolan — The Mission to Get Breakthrough Brain Treatments to Everyone

YouTube video by Juan Benet Podcast

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Biswas Family Foundation @biswasfamilyfdn.bsky.social · 20/05/2026

NEW: $3M in Fast Grants for AI-driven life sciences research. We’re funding pilot projects in AI diagnostics, prediction, and personalized therapeutics — with a two-week review turnaround. 35 grants · $25K–$100K · Deadline: June 15 Please share! www.biswasfamilyfoundation.org/science/fast...

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Alison Gopnik @alisongopnik.bsky.social · 17/05/2026

So pleased that our paper on empowerment and causal models is out and freely available as part of this impressive special issue on world models and AI, with Melanie Mitchell, Josh Tenenbaum, Tom Griffiths and many other stars. royalsocietypublishing.org/rsta/article...

royalsocietypublishing.org

World models, artificial general intelligence and the hard problems of life–mind continuity: toward a unified understanding of natural and artificial intelligence

Abstract. This special issue examines how natural and artificial intelligences (AIs) model the world, and what this modelling reveals about cognition and r

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Sean Escola @seanescola.bsky.social · 06/05/2026

Can the human brain provide the reference architecture for more human-like AI? Coming out of discussions at the PL Neuro Connectomics Workshop last month, Moritz Helmstaedter details a 10-year, $10–20B technical path to map every synapse in the human brain. Read more: zenodo.org/records/1973...

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Protocol Labs @protocollabs.bsky.social · 08/04/2026

PRIMA is a retinal implant from @science.xyz that's already restoring real vision. This is how @maxhodak.bsky.social, founder and CEO of Science, is working to improve lives in meaningful ways. Full conversation on the Juan Benet Podcast >>> bit.ly/4siB7Qp

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Sean Escola @seanescola.bsky.social · 08/04/2026

Great convo painting a positive neurotech future for the world, if we can build it @juanbenet.bsky.social @maxhodak.bsky.social

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Sean Escola @seanescola.bsky.social · 07/04/2026

What is holding #neurotech back from being one of the greatest breakthroughs of our time? Infrastructure. Getting from approval to access takes years — delaying patient access & company capital. PL Neuro aims to break these bottlenecks. Here's our Roadmap: zenodo.org/records/1924...

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Sean Escola @seanescola.bsky.social · 01/04/2026

PL Neuro is officially live! plneuro.xyz We exist to break bottlenecks, accelerate progress in neurotech & NeuroAI, and to invest in innovations that benefit humanity. PL Neuro will focus on 3 core areas: - Neural augmentation - Biologically-inspired intelligence - Whole brain emulation

plneuro.xyz

Homepage — PL Neuro

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Protocol Labs @protocollabs.bsky.social · 31/03/2026

1/ Neurotechnology is one of the defining opportunities of this century. We’re already seeing the potential to restore function, treat disease, and eventually expand human capability.

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Konrad Kording @kordinglab.bsky.social · 31/03/2026

Preprint out arguing that we should build the techology to translate (compile) molecularly annotated connectomes into dynamics. I think this is incredibly important. arxiv.org/abs/2603.25713

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Sean Escola @seanescola.bsky.social · 31/03/2026

Great to work w/ @kordinglab.bsky.social and team on this important roadmap for linking molecular/structural features to function. The future of precision treatments for brain disorders, neurotechnology advances, and an understanding of intelligence itself depend on science that bridges btw scales

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David Sussillo @sussillodavid.bsky.social · 27/03/2026

Honored to share my story of growing up in group homes, and my work in neuroscience, on Armchair Expert!!

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Sean Escola @seanescola.bsky.social · 15/03/2026

We know about cosmological dark matter despite being unable to measure it because, without it, galaxies would fall apart. By analogy, let's talk about "cognitive dark matter" (CDM): brain functions that meaningfully shape behavior but are hard to infer from behavior alone. New paper! 🧵👇

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Neuromatch @neuromatch.bsky.social · 13/03/2026

At #COSYNE2026? #Neuromatch has a booth! Join us for a meetup on Saturday, 14 March at 12:15 at the booth. Whether you're an alumnus, a teaching assistant, a content creator, or just curious about getting involved; this one's for you! #COSYNE #ComputationalNeuroscience #CompNeuro

Bradley Roberts (CEO) and Joana Guedes (Program Manager) seated at the Neuromatch branded booth.

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Patrick Mineault @patrickmineault.bsky.social · 10/03/2026

There's no better way to learn than to teach! Help make NMA a resounding success!

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Protocol Labs @protocollabs.bsky.social · 10/02/2026

The next interface isn’t a screen — it’s neural. PL network team @precisionneuro.bsky.social is working at the intersection of neuroscience and digital interaction, exploring how neural signals can help people with neurodegenerative diseases.

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Bruce Springsteen @brucespringsteen.net · 28/01/2026

I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good. Stay free

youtu.be

Bruce Springsteen - Streets Of Minneapolis (Official Audio)

YouTube video by Bruce Springsteen

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Victoria Bosch @initself.bsky.social · 03/11/2025

Introducing CorText: a framework that fuses brain data directly into a large language model, allowing for interactive neural readout using natural language. tl;dr: you can now chat with a brain scan 🧠💬 1/n

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Sean Escola @seanescola.bsky.social · 21/10/2025

Awesome work from @maxhodak.bsky.social and the Science Corp team

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Sean Escola @seanescola.bsky.social · 28/09/2025

Can’t recommend this opportunity strongly enough!!

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The Transmitter @thetransmitter.bsky.social · 18/07/2025

An exciting collaboration is underway. @thetransmitter.bsky.social is partnering with @neuromatch.bsky.social to serve the computational neuroscience community and help connect neuroscientists across all career stages. www.thetransmitter.org/neuromatch-p... #neuroskyence

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Guillotine Hunger Force @handle.invalid · 17/05/2025

typical corrupt science

=
Nation & World -
The Seattle Times
My Account ™
The T. Rex may have been a lot smarter than you thought
Jan. 9, 2023 at 7:36 am | Updated Jan. 9, 2023 at 7:36 am
By DINO GRANDONI
The Washington Post

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Blake Richards @tyrellturing.bsky.social · 26/03/2025

Eva Dyer and I wrote an opinion piece for @thetransmitter.bsky.social on why neuroscience needs to embrace complexity and accept the "bitter lesson" by using a data-driven regime at scale. With commentary from several wonderful researchers! 🧠📈 #NeuroAI 🧪

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Josh Marshall @joshtpm.bsky.social · 25/03/2025

It's critical for everyone to remember what an Executive Order is. It is the President communicating orders to members of the executive branch. Policies to pursue, actions to take, etc. They are not laws. They are not close to being laws. They are formalized memos to employees. That's all.

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Patrick Mineault @patrickmineault.bsky.social · 17/03/2025

Not to toot my own horn, but Neuromatch's NeuroAI course is one of the best places to learn about this exciting area of neuroscience. Students and postdocs, apply!

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Neuromatch @neuromatch.bsky.social · 17/03/2025

🌟 Teaching Assistants are who make Neuromatch Academy run! 🌟 Thinking of becoming a Teaching Assistant (TA) for Neuromatch or Climatematch Academy? Here’s why you should GO FOR IT! 🚀 Learn more and apply here: neuromatch.io/courses/ #Education #TA #TeachingOpportunity #mentorship

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Sean Escola @seanescola.bsky.social · 05/03/2025

Do some science! Make some friends!

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Neil deGrasse Tyson @neildegrassetyson.com · 15/02/2025

At the moment, mansion-sized Asteroid 2024-YR4 has a one-in-fifty chance of hitting Earth in the next eight years. Now might be a bad time to reduce spending on Science. Just sayin’.

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David Pfau @davidpfau.com · 28/01/2025

Remember how, when the lockdowns started, every organization said "we only have two weeks of cash on hand and will shut down if we don't get assistance"? That's basically happening to every single lab and NGO right now, except for no actual reason.

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Adam Marblestone @adammarblestone.bsky.social · 08/01/2025

🚀 Calling all visionary scientists and engineers! Announcing our call for Focused Research Organization proposals in the UK. 🔬Submit your concept paper by Feb 7 & full proposal by March 28. More here: www.convergentresearch.org/frost-uk ⤵️

convergentresearch.org

FROST UK — Convergent Research

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Blake Richards @tyrellturing.bsky.social · 26/12/2024

I don't think traditional systems neuroscience fits my definition, as it has rarely concerned itself with general principles of intelligence that apply to non-biological systems.

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David Pfau @davidpfau.com · 23/12/2024

So, they set up the ARC prize specifically to have limits on how much compute you can use, required the submissions to be open-sourced, and then OpenAI just went ahead and crushed it with >$1m of compute from a closed model with no idea how it works anyway? Do I have that right?

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Sean Escola @seanescola.bsky.social · 15/12/2024

I like this definition (although it’s not the one I’ve typically espoused). It basically says that #NeuroAI is intelligence science writ large. And the name works because our current options for intelligence are either neural or artificial

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Sean Escola @seanescola.bsky.social · 13/12/2024

Have a read of @davidamarkowitz.bsky.social’s proposal to accelerate intelligence science with new institutions in @thetransmitter.bsky.social #NeuroAI

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Tony Zador @tonyzador.bsky.social · 03/12/2024

Estimate from @mbeisen.bsky.social that about $1.5B (3%) of the $50B NIH budget goes to publishing fees. If we are looking to cut government waste, this might be a good place to start.

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Surya Ganguli @suryaganguli.bsky.social · 19/11/2024

The time is now to argue vociferously for immense societal and economic value of public investment in scientific research. But unfortunately that argument must be made not to the choir in our beautiful blue bubble here, but in the arena of X where said value is now questioned: x.com/suryaganguli...

x.com

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David A. Markowitz @davidamarkowitz.bsky.social · 13/11/2024

Unpopular opinion: If you are a scientist who doesn't participate in science advocacy outside your filter bubble, you are doing yourself a disservice. Bluesky is intellectually fun, but the people who will soon be making decisions about government science funding priorities are not on here.

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Laureline Logiaco @laurelinelogiaco.bsky.social · 10/11/2024

We (w/ @seanescola.bsky.social & K Lakshminarasimhan) recently wrote a review covering different types of thalamocortical models for motor control. Here is a link to a related talk. Giving a wide perspective & discussing a large body of work was both very challenging & rewarding. Thank you, Andrew!

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