iiinova — where your digital self keeps evolving

Reposted by Shivani Dharmadhikari

preLights @prelights.bsky.social · 25/02/2026

How to make a 4-cell square ascidian embryo? Cytoplasmic pulling rotates centrosomes, cortical forces lock the plane. Corentin Mollier & Shivani Dharmadhikari highlight a #preprint from Silvia Caballero-Mancebo & team @rdumollard.bsky.social #preLight ⬇️ prelights.biologists.com/highlights/c...

prelights.biologists.com

Cooperation between cortical and cytoplasmic forces shapes planar 4-cell stage embryos - preLights

How to make a 4-cell square ascidian embryo? Cytoplasmic pulling rotates centrosomes, cortical forces lock the plane.

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 25/01/2026

One the most lovely combinations of science and art I have been to in a long time at Musée d’Orsay☺️✨ by the @manuelthery.bsky.social #cytomorpholab

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Reposted by Shivani Dharmadhikari

Manuel Thery @manuelthery.bsky.social · 05/12/2025

#LivingArchitectures We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay. www.musee-orsay.fr/fr/agenda/ev... Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night. -> Two shows on the 24th and 25th of January.

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 13/11/2025

A fun way to recover embryos on a grey Parisian day 🌧️🐭

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 07/08/2025

Spent a memorable summer at Physiology course at @mblscience.bsky.social Very coooool science with some lovely people! Thanks @brangwynnelab.bsky.social and @gladfelterlab.bsky.social for being amazinnnng course coordinators! 🧵

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Reposted by Shivani Dharmadhikari

Tanner Fadero @tanner-fadero.bsky.social · 04/02/2025

I'll kick off my bsky profile with a great 3D fluorescence microscopy time-lapse. My buddies Joe Brzostowski and Rachel Stadler (NIH) acquired this on their #snoutscope that I helped them build. Shown is a fluorescent actin marker in Dictyostelium. Joe and Rachel called this "The Mark of Zorro!"

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Reposted by Shivani Dharmadhikari

Marine Biological Laboratory @mblscience.bsky.social · 25/06/2025

MBL scientists use skates and their embryos to study skeletal development. By shining a light through egg cases, scientists can watch the entire maturation process. Learn more about skates as a research organism here: bit.ly/3Rmvq3F 📹 Bioquest

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Reposted by Shivani Dharmadhikari

brangwynnelab.bsky.social @brangwynnelab.bsky.social · 18/06/2025

The one and only Manu @prakashlab.bsky.social inspiring @mblscience.bsky.social Physiology students at this morning's lecture.

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Reposted by Shivani Dharmadhikari

brangwynnelab.bsky.social @brangwynnelab.bsky.social · 17/06/2025

A great morning with the @mblscience.bsky.social Physiology students after my talk today.

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Reposted by Shivani Dharmadhikari

Erwin Frey @physicsoflifelmu.bsky.social · 31/03/2025

We may not have really squared the circle — but we came close! 😉 In our @NaturePhysics paper w/ @fakhrilab.bsky.social, light-triggered membrane excitability enables programmable shapes — a step toward engineering living matter. 🔗 www.nature.com/articles/s41... #biophysics #syntheticcell #softmatter

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 24/04/2025

Is there a pattern of how they arrange in the drop or have I been staring through the microscope for far toooo long? 🧐😁#beautifulembryos

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Reposted by Shivani Dharmadhikari

Viroscope @viroscope.bsky.social · 21/03/2025

New cell line = New cell morphologies to explore! This hepatic cell line has fully invested into membrane protrusions! Actin is shown in 🟦 and DNA in 🟧 #FluorescenceFriday #SciArt

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Reposted by Shivani Dharmadhikari

John Wallingford @jbwallingford.bsky.social · 11/03/2025

A woman studies embryos for decades, struggles for funding and respect. She publishes under her husband’s name, until they divorce. A single mother, she moves across an ocean to continue her studies. It all sounds quite modern, until you learn that she also worried she’d be burned as a witch. 🧵 1/15

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 09/02/2025

Lovely work on shape evolution! Check out the story below:)

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 05/02/2025

As a biologist, we have to often choose colors and the way of representation of data..but Pierre-Joseph Redouté’s plant illustrations are amazing and Nicholas Rougeux's collation and post processing and representation of data is beautiful! Lots of amazing stuff! check here - www.c82.net/work/

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 04/01/2025

Interesting topic and a lovely lab to work in! Don’t miss out on the opportunity!

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 27/12/2024

Such an important way of progressing in any scientific question, yet so undervalued!

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 18/12/2024

There is the beast of the year! Little hunting 🐙 And the beauty by Manon’s lovely heart! Its nice to be a part of the yearly tradition! 🎄

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Reposted by Shivani Dharmadhikari

Thibaut Brunet @thibautbrunet.bsky.social · 07/12/2024

Yes! everybody has their favorite early Metchnikoff paper (before he moved on to such secondary pursuits as discovering innate immunity). Mine: his early intuition that animals evolved from colonies of flagellates that could transdifferentiate into amoebae - 100y before molecular phylogenies!

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 30/11/2024

An interesting read! An article from John Hopfield on how he chooses to work on the next question(now what?)… a question, as a scientist we often ask ourselves! pni.princeton.edu/people/john-...

pni.princeton.edu

Now What?

John J. Hopfield, Princeton University, Princeton, NJ 08544, USA. October 2018 John J. Hopfield Now What? (Article in PDF format) My first full-time permanent employment was at the Bell Telephone Labo...

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Reposted by Shivani Dharmadhikari

Michalis Averof @michalis-averof.bsky.social · 12/11/2024

Looking for a tag to localise fluorescent proteins to the plasma membrane? Unsure which tag might work in your species? We generated a toolkit of 11 membrane-localising tags, which can be screened rapidly by microinjecting mRNA in your species of interest. 1/4 www.biorxiv.org/content/10.1...

biorxiv.org

A toolkit for testing membrane localisation tags across species

Transgenic markers and tools have revolutionised how we study cells and developing organisms. Some of the elements needed to construct those tools are universally applicable (e.g. fluorescent proteins...

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Reposted by Shivani Dharmadhikari

Jean Léon Maître @maitrejl.bsky.social · 26/11/2024

Congrats to double Doctor Julie Firmin on receiving the prize for her Great Advances in Biology from the Academie des Sciences!

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 22/11/2024

Early mouse morula! Almost two years ago, I imaged my very first mouse embryo and since then I haven’t gotten over the funny apical domains (cyan)😍 nostalgic :) This beauty was part of the first immunostaining, I did when I joined the lab! #fluoroscentfriday

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 21/11/2024

First snow of the year!! For someone who was used to 30 degrees all year along, snowing is special❄️🌨️ I will try to work today😉

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 19/11/2024

Hatching blastocyst! When you fix the embryos wayyyy later than you wanted to, because you got caught up;) still a beautiful one though 😉☺️

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Reposted by Shivani Dharmadhikari

Informationsdienst Wissenschaft - idw @idw-online.de · 21/10/2024

Ovulation filmed from start to finish for the first time Approximately 400 times in a woman's life, a mature egg makes the “leap.” It is released into the fallopian tube, ready for fertilization by the sperm. Researchers led by Melina Schuh,... weiterlesen

The image shows an egg that has just been ovulated next to the follicle. - Copyright Max Planck Institute for Multidisciplinary Sciences

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Reposted by Shivani Dharmadhikari

Kirsty Wan @micromotility.bsky.social · 13/11/2024

Couldn't find one so made a quick physics of life list, enjoy! go.bsky.app/EA2VsDN

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Shivani Dharmadhikari @sdharmadhikari.bsky.social · 17/11/2024

Fun movie of the cell surface of mouse morula. Jiggly protrusions, now the task of quantifying them💪 Any suggestions!?

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Reposted by Shivani Dharmadhikari

Kirsty Wan @micromotility.bsky.social · 11/11/2024

Move over C. elegans... single celled protist wriggles forwards and backwards! Check out the beautiful ciliary metachronal waves #didinium #protistsonsky

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