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Steffen Scholpp

@scholpplab.bsky.social
2.7K followers 2.7K following 164 posts

I am a cell and developmental biologist at the Living Systems Institute (LSI) in Exeter. We work on spreading Wnt signals and characterising cytonemes in zebrafish embryos, human neurons, and cancer using high-res imaging and mathematical modelling.

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Steffen Scholpp @scholpplab.bsky.social · 16h
Great two days at our Wnt SFB 1324 meeting @heidelberg ! 🧬 Fantastic science, fresh ideas, new tools & lots of exciting collaborations. Great to have Lizzy, Gemma & Jess presenting their work and getting inspired. Now back @lsiexeter.bsky.social to try it all out! 🔬🐟 #Wnt #Cytonemes
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Steffen Scholpp @scholpplab.bsky.social · 17/09/2026
How does a Wnt cytoneme contact become a productive signalling site? Emma Cooper and colleagues find focal Ca²⁺ transients at cytoneme contacts and link Ca²⁺ availability to contact stability and Wnt/β-catenin signalling. www.biorxiv.org/content/10.6... #Wnt #Cytonemes #CellBiology
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Steffen Scholpp @scholpplab.bsky.social · 23/07/2026
A fantastic start to our first @wellcometrust.bsky.social Cytoneme Network Workshop @lsiexeter.bsky.social, bringing together our Exeter and Manchester teams. Excited to uncover the unifying principles of contact-mediated signalling of Wnt, Notch, & Dpp in Drosophila, fish & mice. Cytonemes rock!
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Steffen Scholpp @scholpplab.bsky.social · 14/07/2026
Back where it all started! Great to visit my old PhD lab and catch up with Michael. Fascinating to see the impressive progress in brain regeneration research using #zebrafish. Thanks for the warm welcome and inspiring discussions. Always a pleasure to come back!
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Steffen Scholpp @scholpplab.bsky.social · 12/07/2026
Fantastic presentations of PhD students, postdocs, ECRs, and PIs from all the zebrafish groups in Exeter at #EZM2026 - well done everyone! Exeter is becoming a central hub for research using zebrafish as a model organism in the UK and Europe. #LSIZebrafsihHub @lsiexeter.bsky.social @exeter.ac.uk
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Steffen Scholpp @scholpplab.bsky.social · 08/07/2026
Exeter is making waves at #EZM2026! Fantastic to see so many brilliant Exeter posters from development & disease to imaging&gene editing; great science & great people. From the West Country to Europe: Exeter is becoming a real zebrafish hotspot. Come say hi! @exeter.ac.uk @lsiexeter.bsky.social
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Steffen Scholpp @scholpplab.bsky.social · 09/06/2026
I guess one with MERFISHEYES.....
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Steffen Scholpp @scholpplab.bsky.social · 09/06/2026
The LSI Zebrafish Hub is very excited to welcome Prof Alex Schier - @schierlab.bsky.social - from the @biozentrum.unibas.ch for our Joint LSI/Biosciences Distinguished Seminar @lsiexeter.bsky.social tomorrow! Please come along & join us! #zebrafish #developmentalbiology @zebrafishrock.bsky.social
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Steffen Scholpp @scholpplab.bsky.social · 06/06/2026
After months of experiments, failed injections, unexpected results, and those rare moments when everything suddenly works - our manuscript is finally submitted. Read our newest story about a journey of tiny vesicles carrying big biological messages, now in bioRxiv. www.biorxiv.org/content/10.6...
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Steffen Scholpp @scholpplab.bsky.social · 26/05/2026
It was a pleasure to showcase our most recent data on cytonemes to the cell biology community in Bristol, including a long discussion about morphogen distribution mechanisms. Zebrafish cell biology rocks!
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Steffen Scholpp @scholpplab.bsky.social · 19/05/2026
Today’s lab meeting came with proper birthday celebrations for our two birthday girls and, thanks to Jess, not one but two cakes. A very strong experimental design: double cake input, significantly improved lab morale output. Cake really does make all data sweeter.
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Steffen Scholpp @scholpplab.bsky.social · 14/05/2026
Wonderful PhD Day @lsiexeter.bsky.social today - full of great science, interdisciplinary projects, lively discussions and lots of laughter. Huge congratulations to our PhD students Jess Bansey and Lizzy Sears for winning Best Talk & Best Flash Talk Award. Very proud of you both! 👏 #PhDLife #ECRs
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Steffen Scholpp @scholpplab.bsky.social · 07/05/2026
Very happy to share that I have joined the Heidelberg CRC/SFB 1324 “Mechanisms and Functions of Wnt Signalling” as a DFG Mercator Fellow. Looking forward to linking our work @lsiexeter.bsky.social with @cosheidelberg.bsky.social. Wonderful to hear Gemma's excellent presentation on cytonemes.
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Steffen Scholpp @scholpplab.bsky.social · 16/03/2026
How many fish researchers fit into a tiny elevator? Answer; apparently all of us! Unexpected outcome: massively improved team spirit! 🐟📸
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Steffen Scholpp @scholpplab.bsky.social · 20/01/2026
We are delighted to launch the Centre for Cellular Life, a new partnership between the @lsiexeter.bsky.social and SKLMB, Tsinghua University. Interdisciplinary science will drive collaborative research, researcher mobility and doctoral training to tackle how cells function in health and disease.
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Steffen Scholpp @scholpplab.bsky.social · 22/12/2025
Back in my old uni city. Where the memories are strong, the coffee tastes familiar, and the colleagues somehow look the same 😄
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Steffen Scholpp @scholpplab.bsky.social · 15/12/2025
End-of-year lab meeting powered by Jellycat-style cake creatures 🐟🧁. Smiling faces, great results, and a lot to celebrate from 2025. Here is to the same momentum in 2026 (and more cake from Lizzy et al.). 🍰
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Steffen Scholpp @scholpplab.bsky.social · 12/12/2025
Great to see our collaboration between @tsinghuauniversity.bsky.social and the @lsiexeter.bsky.social taking shape after a fantastic visit to Beijing. We have established a strong foundation for joint research projects starting in 2026. Thanks to Li Yu and Fan Zhou for the excellent organisation.
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Steffen Scholpp @scholpplab.bsky.social · 01/10/2025
Back from the London Zebrafish Research Network — a truly inspiring afternoon. Many thanks to @cvagenapantoula.bsky.social, @kkalyviotis.bsky.social and Eleni for putting together such an interactive programme, full of excellent talks - Tim 👏 - and great discussions. Zebbie research at its best!
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Steffen Scholpp @scholpplab.bsky.social · 19/09/2025
A huge thank you to everyone who made #UKZF2025 possible 🙌🐟 From inspiring talks and posters to lively discussions and community spirit — your energy and contributions turned this meeting into a real success. 💙✨
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Steffen Scholpp @scholpplab.bsky.social · 12/09/2025
All the hard work during the workshop at #UKZF2025 🐟💡 was rewarded with a joyful gala dinner — science, community & celebration coming together in style ✨🥂
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Steffen Scholpp @scholpplab.bsky.social · 11/09/2025
One of the best parts of #UKZF2025 🐟✨ — old friends reconnecting, new colleagues meeting for the first time, all sharing ideas and energy to drive science forward together 💡🤝
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Steffen Scholpp @scholpplab.bsky.social · 10/09/2025
Day 1 of #UKZF2025 is here! 🎉🐟 The conference kicks off in Exeter & Exmouth — packed with science, networking, and community. Let’s dive in! 🚀 @izfs.bsky.social @zebrafishrock.bsky.social @lsiexeter.bsky.social @zebrafishhusbandry.bsky.social
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Steffen Scholpp @scholpplab.bsky.social · 10/09/2025
What started as a small idea has grown into a buzzing UKZF2025 — and now we’re treated to an incredible line-up of super science talks from our brilliant UK ECRs! 🐟✨ #UKZF2025
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Steffen Scholpp @scholpplab.bsky.social · 10/09/2025
🐟🎟 Long queues at the #UKZF2025 registration desk this morning — thank you all for your patience and enthusiasm! The buzz is real, and we’re so excited to get started 🚀
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Steffen Scholpp @scholpplab.bsky.social · 10/09/2025
It’s all coming together beautifully — #UKZF2025 is really taking shape 🐟✨ We can’t wait to share this vibrant meeting with you all!
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Steffen Scholpp @scholpplab.bsky.social · 10/09/2025
🚨 Final bits are falling into place for #UKZF2025 🎉 The organisers are buzzing with excitement and can’t wait to welcome the zebrafish community to Exeter & Exmouth TODAY 🐟✨
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Steffen Scholpp @scholpplab.bsky.social · 30/07/2025
Team BBQ yesterday: sun, sizzle, and seriously good food! But also bittersweet as we said goodbye (for now) to two fab members 😢. Lucy is off on maternity leave to grow a tiny scientist. Eloise is swapping pipettes for passport stamps. We’ll miss them both-but remember, our lab door is always open!
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Steffen Scholpp @scholpplab.bsky.social · 23/07/2025
Huge congratulations to our brilliant graduates: one newly minted PhD, a sharp MSc, and two stellar BScs! You all looked majestic in your gowns — a well-earned symbol of your hard work, late nights, and scientific curiosity. Serious achievements, bright futures. @lsiexeter.bsky.social @exeter.ac.uk
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Steffen Scholpp @scholpplab.bsky.social · 20/06/2025
Power presentation of Bertram about the beauty of cryo EM at the #LSIOpenDay. @lsiexeter.bsky.social
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Steffen Scholpp @scholpplab.bsky.social · 17/06/2025
Time is running out to present your latest #Zebrafish research at ZFUK25 tinyurl.com/mw7r3nbn in Exeter. This is your chance to share your work, connect with the community, and contribute to cutting-edge discussions. The deadline for abstract submission is rapidly approaching: 30th June 2025!
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Steffen Scholpp @scholpplab.bsky.social · 11/06/2025
Thrilled to announce a seminar featuring Prof. Hilary Ashe, a leading Cell & Developmental Biologist from @UoM_BioSci! Discover her lab's latest findings on spatiotemporal gene expression & cell communication in #Drosophila @lsiexeter.bsky.social
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Steffen Scholpp @scholpplab.bsky.social · 09/06/2025
Excellent presentation of the function of cytonemes in neural crest specification from Gemma Sutton GW4 Imaging workshop @lsiexeter.bsky.social @gw4alliance.bsky.social Cytoneme biology rocks!
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Steffen Scholpp @scholpplab.bsky.social · 05/06/2025
My next stop is CRUK Scotland in Glasgow. Thanks to Owen Sansom @cruk-si.bsky.social for hosting me. The @wntuk.bsky.social community is just awesome—great people, excellent research!
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Steffen Scholpp @scholpplab.bsky.social · 05/06/2025
I had an excellent visit to the @roslininstitute.bsky.social. They do amazing developmental biology research. Thanks to Joe Rainger for hosting me!
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Steffen Scholpp @scholpplab.bsky.social · 14/05/2025
Early bird registration ends tomorrow! We already have a large number of registrations, and we are pleased to announce that the Genetics Society @gensocuk.bsky.social is now an official sponsor of the First ZF UK Meeting! Be quick and register today: www.exeter.ac.uk/research/ins...
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Steffen Scholpp @scholpplab.bsky.social · 07/05/2025
It's time for a new @skircle.bsky.social ; skircle.me
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Steffen Scholpp @scholpplab.bsky.social · 07/05/2025
Don't miss the First UK Zebrafish Meeting @lsiexeter.bsky.social in Exeter, sponsored by @brukercorporation.bsky.social @brukerspatial.bsky.social al.bsky.social! 🐠 Join us Sept 10 - 12. Early bird registration closes soon! Secure your spot. www.exeter.ac.uk/research/ins...
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Steffen Scholpp @scholpplab.bsky.social · 28/04/2025
We're excited to announce that Tecniplast www.tecniplast.it/uk/index.html will be our first Platinum Sponsor for the first UK Zebrafish Meeting @lsiexeter.bsky.social. You want to present your work (talk or poster)? Early-bird registration deadline is 15/5/. Don't delay! #Zebrafish #ECR #PhD
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Steffen Scholpp @scholpplab.bsky.social · 24/04/2025
We are happy to announce that @biologists.bsky.social will sponsor the first UK Zebrafish Meeting @lsiexeter.bsky.social. Are you a PhD student/ECR who wants to present your work? Talk or poster? 👍 Deadline for the early bird registration is 15/5/. So, be quick! www.exeter.ac.uk/research/ins....
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Steffen Scholpp @scholpplab.bsky.social · 24/04/2025
We are happy to announce that The Company of Biologists will sponsor the first UK Zebrafish Meeting @lsiexeter.bsky.social . Are you a PhD student / ECR who wants to present your work as a talk or on a poster? 👍 The deadline for the early bird registration is 15/5/. So, be quick! lnkd.in/eqQH_pCW .
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Steffen Scholpp @scholpplab.bsky.social · 14/04/2025
The LSI Exeter invites you to join the first UK Zebrafish Meeting, 10/ - 12/9/ @lsiexeter.bsky.social. We are looking for motivated PhD students/ECRs to present their work - as talks and posters. www.exeter.ac.uk/research/ins... . The deadline for the early bird registration is 15/5/. So, be quick!
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Steffen Scholpp @scholpplab.bsky.social · 14/03/2025
Excellent inaugural presentation by Prof Stefano Pagliara. Thanks for the engaging talk on antimicrobial resistance! @exeter.ac.uk @lsiexeter.bsky.social
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Steffen Scholpp @scholpplab.bsky.social · 06/03/2025
In 2022, we organised an EMBO meeting to discuss cytoneme-mediated signalling @lsiexeter.bsky.social. Today, 2 of our speakers, @michellemonje.bsky.social and @frankwinkler.bsky.social, received the highly prestigious @brainprize.bsky.social for researching cytoneme synapses. Isn't that excellent?
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Steffen Scholpp @scholpplab.bsky.social · 06/03/2025
What a great walk across Streatham Campus to my morning lecture @lsiexeter.bsky.social @uniexecec.bsky.social
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Steffen Scholpp @scholpplab.bsky.social · 05/02/2025
BBSRC fellowships are now open! If anyone is interested in applying to join my team and working on Wnt signalling, growth factor transport mechanisms, cytonemes and zebrafish @lsiexeter.bsky.social then send me a PM! www.ukri.org/opportunity/...
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Steffen Scholpp @scholpplab.bsky.social · 10/01/2025
Evening run after a very productive Friday. Yes!
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Steffen Scholpp @scholpplab.bsky.social · 09/01/2025
What a delightful remedy for the January blues. Light & Sound show @exetercathedral.bsky.social.
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Steffen Scholpp @scholpplab.bsky.social · 08/01/2025
It's so great starting the year with some ginger biscuits! Thanks to Gemma, our "new" postdoc: Zebrafish Rocks, also in 2025! @lsiexeter.bsky.social @zebrafishrock.bsky.social
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Steffen Scholpp @scholpplab.bsky.social · 06/01/2025
Happy New Year! I hope 2025 is good for you all. We start this year with a somewhat controversial review. www.sciencedirect.com/science/arti.... Here, we discuss how a cell receives signalling receptors from neighbouring cells, allowing the receivers to transduce a previously unknown signal. 1/3
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