Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 09/04/2026Happening tomorrow! @lonniepyne.bsky.social from McMaster will present on eGFR changes as outcomes of interest #NephGR #NephSky 083
Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 13/02/2026The 2.0 version of the Ontario Renal Network #KidneyWise toolkit is live now www.ontariorenalnetwork.ca/en/kidney-ca... From @sbrimble.bsky.social and team - referral forms - referral criteria - guidance on CKD mgt for PCPs #NephSky #MedSkyontariorenalnetwork.caKidneyWise Toolkit 012
Reposted by @sbrimble.bsky.socialASN Publications @asnpublications.bsky.social · 11/09/2025What are the most important risk factors for suboptimal dialysis initiation? In #ASNKidney360, this article investigates within a prospective cohort study. Read more: kidney.pub/KID0895 @hswapnil.medsky.social @sbrimble.bsky.social 022
Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 30/07/2025We called it unplanned pubmed.ncbi.nlm.nih.gov/30899532/ but suboptimal seems more common @sbrimble.bsky.socialpubmed.ncbi.nlm.nih.govRisk Factors for Unplanned Dialysis Initiation: A Systematic Review of the Literature - PubMedWell-designed prospective studies to determine modifiable risk factors are needed. The lack of a consensus definition for unplanned dialysis makes research and quality improvement initiatives in this ... 021
Reposted by @sbrimble.bsky.socialMichael Walsh @lastwalsh.bsky.social · 05/06/2025It's been a long journey but today we can share the methods and rationale for the #ACHIEVEtrial (Spiro vs placebo for patients with kidney failure receiving maintenance dialysis) and tomorrow we share the results at #era25 journals.sagepub.com/doi/10.1177/...journals.sagepub.comThe Aldosterone Blockade for Health Improvement Evaluation in End-Stage Renal Disease (ACHIEVE) Trial: Rationale and Clinical Research Protocol - Michael Walsh, David Collister, Martin Gallagher, Patr...Background: The mineralocorticoid aldosterone may contribute to the risk of cardiovascular morbidity and mortality in patients receiving maintenance dialysis. W... 22510
Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 16/04/2025As an example Guidelines hijacked by industry for decades 021
Reposted by @sbrimble.bsky.socialDorothy Bishop @deevybee.bsky.social · 16/04/2025some of the most striking tortured phrases i’ve seen in a while. Look here to discover what “moo warm steadiness” is pubpeer.com/publications...pubpeer.comPubPeer - Adsorption of heavy metals from wastewater by chitosan: A re...There are comments on PubPeer for publication: Adsorption of heavy metals from wastewater by chitosan: A review (2024) 95118
Reposted by @sbrimble.bsky.socialderek guy @dieworkwear.bsky.social · 08/04/2025a lot of people think you need a lot of money to buy clothes. now you're right. ok. my bad. 165195431660
Reposted by @sbrimble.bsky.socialRick @rickylongthread.bsky.social · 06/04/2025THIS IS WHAT A TRADE WAR LOOKS LIKE - 453176343789
Reposted by @sbrimble.bsky.socialLonnie Pyne @lonniepyne.bsky.social · 02/04/2025First and only? Can’t be such a stickler as to ignore the PIVOTAL trial. PIVOTAL trial effect estimate on all-cause mortality HR 0.84 (95% CI 0.71 to 1) I do think expecting anything to improve all-cause mortality in ESRD is probably unwise. www.nejm.org/doi/full/10....nejm.orgIntravenous Iron in Patients Undergoing Maintenance Hemodialysis | NEJMIntravenous iron is a standard treatment for patients undergoing hemodialysis, but comparative data regarding clinically effective regimens are limited. In a multicenter, open-label trial with blin... 073
Reposted by @sbrimble.bsky.socialChristopher Webb @cwebbonline.com · 22/03/2025Pete Buttigieg breaks down DEI for everyday folks… “The opposite of diversity is uniformity. The opposite of equity is inequity. The opposite of inclusion is exclusion.” @petebuttigieg.bsky.social Our problem: too many value uniformity over inclusion and they’re the ones running the government. 🧵 11874440914463
Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 01/02/2025It’s been 25 years - RenalWeek was in Toronto in 2000 Time to bring it back 😎 1206
Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 17/03/2025Ugh Dr Jayme Locke (you may know from the XenoTransplant story) hired from UAB to fix the transplant system (that is abysmally awful if you have followed @sumitmohan.bsky.social ) But she was ‘probabtionary’ so DOGE fired her 🤦🏽♂️ @wsj.com story on 🍎 News $wall apple.news/Ans49CVgKQy-... #NephSky 12616
Reposted by @sbrimble.bsky.socialWalking Eagle News @theeagleist.bsky.social · 16/03/2025First Nations offer to buy ‘iconic’ Hudson’s Bay store chain for tobacco, blanket 161079291
Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 17/03/2025Did you know the @csnscn.bsky.social has a jobs board ? www.csnscn.ca/job-board/csnscn.caJob Board - CSN/SCNCURRENT POSITIONS Clinician Teacher in the Section of NephrologyUniversity of ManitobaApplication Deadline: Until Position Is Filled Application Deadline: Until the Position Is Filled NephrologistDalh... 162
Reposted by @sbrimble.bsky.socialCatherine Clase @catherineclase.bsky.social · 15/03/2025Dr Rasha Alawieh, assistant professor in transplant nephrology at Brown, detained at airport after travel to Lebanon, despite valid H-1B visa #nephsky #transplantsky #medsky www.browndailyherald.com/article/2025... @kateschapira.bsky.social @brownmedicine.bsky.socialbrowndailyherald.comBrown University professor held by customs officials at airport after travel to LebanonServing the Brown community since 1891 23719
Reposted by @sbrimble.bsky.socialTechmeme @techmeme.com · 11/03/2025A study of eight AI search engines found they provided incorrect citations of news articles in 60%+ of queries; Grok 3 answered 94% of the queries incorrectly (Columbia Journalism Review) Main Link | Techmeme Permalink 28666273
Reposted by @sbrimble.bsky.socialMichelle Rheault, MD @rheaultm.bsky.social · 08/03/2025Prospective Cohort Study in #Alport Syndrome Patients under Standard Therapy - the ATHENA study www.kireports.org/article/S246...kireports.orgProspective Cohort Study in Alport Syndrome Patients under Standard TherapyPatients with Alport syndrome, a common genetic kidney disease, exhibit variable rates of decline in kidney function. Consequently, this global, multicenter, prospective observational study aimed to g... 1278
Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 03/03/2025This table from @drjmluther.bsky.social needs to be disseminated more widely (We added it to our @cmaj-jamc.bsky.social 5 things for that reason www.cmaj.ca/content/196/...) #NephMadness 21311
Reposted by @sbrimble.bsky.socialPatrick Hickey, MD @pwhickey.bsky.social · 02/03/2025I learned that around 3 million military connected kids- largely children of veterans who have left the service are dependent on Medicaid. This breaks my heart both at the threat to their healthcare access and the fact that we clearly need to do more to help veterans make this transition 226677
Reposted by @sbrimble.bsky.socialASN Publications @asnpublications.bsky.social · 01/03/2025Genetic regulation of plasma sodium concentration is variable and pathways involving the pituitary gland have an important role. There is no evidence of genetic predisposition for the plasma sodium-lowering effect of thiazides. bit.ly/JASN0622 #ASNJASN #BasicResearch 094
Reposted by @sbrimble.bsky.socialAtul Gawande @agawande.bsky.social · 27/02/2025Rubio terminated 5800 USAID contracts – more than 90% of its foreign aid programs – in defiance of the courts. Here’s a list of just some of the lifesaving awards that were terminated. Nearly all were Congressionally mandated. They’ve saved millions of lives. 🧵 420112356200
Reposted by @sbrimble.bsky.socialJarcy Zee @jarcyzphd.bsky.social · 27/02/2025Just beware the "time-averaged proteinuria" methodology was flawed because it uses future information to predict the future at baseline and could be exaggerating effects. See our paper on this unfortunately popular method in nephrology literature: doi.org/10.2215/CJN....doi.orgMethods for Assessing Longitudinal Biomarkers of... : Clinical Journal of the American Society of Nephrologyassessed accuracy of methods using computer simulations and compared biomarker association estimates in the NEPhrotic syndrome sTUdy NEtwork (NEPTUNE), a prospective cohort study of patients with glom... 076
Reposted by @sbrimble.bsky.socialJordy Cohen @jordybc.bsky.social · 26/02/2025Agree. Would almost always opt for a better agent. *Except* I recently learned it’s the only RAS blocker that’s thought to be semi-ok while breast feeding! www.ncbi.nlm.nih.gov/books/NBK500...ncbi.nlm.nih.govEnalaprilBecause of the low levels of enalapril in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants. 185
Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 26/02/2025Agree with Scott Even in HFrEF they used up to 20 mg enalapril (eg www.nejm.org/doi/full/10....) so to cap at 10 mg for HT is quasi-homeopathic Also Why use enalapril at all?nejm.orgEffect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure | NEJMPatients with congestive heart failure have a high mortality rate and are also hospitalized frequently. We studied the effect of an angiotensin-converting–enzyme inhibitor, enalapril, on mortality ... 121
Reposted by @sbrimble.bsky.socialSayna Norouzi, MD @saynanorouzi.bsky.social · 26/02/2025Are you effectively preventing VTE in your patients with nephrotic syndrome? Check out our paper below on KI reports about this important topic. It's a fantastic collaboration with some truly brilliant minds! #NephSky @glomcon.org www.kireports.org/article/S246...kireports.orgVenous thromboembolism prevention for nephrotic syndrome: The role of aspirin, vitamin K antagonists and direct oral anticoagulantsNephrotic syndrome (NS) carries a significantly elevated risk of venous thromboembolic events (VTE), contributing to morbidity and mortality. Current guidelines for VTE prophylaxis in NS are based on ... 11610
Reposted by @sbrimble.bsky.socialCJKHD @cjkhd.bsky.social · 24/02/2025Case Series of Infection-Related #Glomerulonephritis (IRGN) in Quebec Indigenous Peoples: Heterogenous clinical, laboratory, and pathological presentations that make the diagnosis of #IRGN quite challenging. @csnscn.bsky.social @cjkhd.bsky.social doi.org/10.1177/2054...doi.orgSage Journals: Discover world-class researchSubscription and open access journals from Sage, the world's leading independent academic publisher. 022
Reposted by @sbrimble.bsky.socialgrahamabra.bsky.social @grahamabra.bsky.social · 21/02/2025Dear @gavinnewsom.bsky.social, As you are well aware, California has the largest number of undocumented immigrants in the United States with an estimated 2.6 million individuals according to the Department of Homeland Security. 153
Reposted by @sbrimble.bsky.socialSwapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 15/02/2025Our last #ISNWCN debate on protein restriction in CKD is now published - #OpenAccess pubmed.ncbi.nlm.nih.gov/39933007/ with @kidneyboy.bsky.social and Abdullah Bawazir, OttawaRenal fellow #NephSkypubmed.ncbi.nlm.nih.govProtein restriction in CKD: an outdated strategy in the modern era - PubMedChronic kidney disease (CKD) management has traditionally emphasized dietary protein restriction to slow disease progression and delay end-stage renal disease (ESRD). However, evidence from trials que... 13113
sbrimble.bsky.social @sbrimble.bsky.social · 02/02/2025Lovely day for a walk in these troubling times. A white-throated sparrow. #bird 030
Reposted by @sbrimble.bsky.socialgrahamabra.bsky.social @grahamabra.bsky.social · 30/01/2025Breaking news: Dual RAAS blockade still doesn’t work 0112
Reposted by @sbrimble.bsky.socialgrahamabra.bsky.social @grahamabra.bsky.social · 26/01/2025Great talk! His argument to treat the immunologic disease not the CKD particularly early in the course is very appealing We need to test it in an RCT! The big trials typically have pts on some/max RAASI as inclusion/run-in Great that we can start thinking differently! 112
Reposted by @sbrimble.bsky.socialJAMA @jama.com · 20/12/2024Adolescents and young adults receiving care at dialysis facilities with higher patient to staff ratios had reduced access to waitlisting and transplant, particularly if they were younger than 22 years at dialysis initiation. ja.ma/41FEgzO 0124
