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I’m confident in my mastery over what doctors do — and less confident about my continued mastery of an ever-evolving universe of facts.

One life, drawn at random from all who have ever lived.

This feature about a healthy person’s visit to a physician offers a case vignette accompanied by two essays, one recommending that the physician perform a routine physical examination and the other .....

The best argument against his nonsense is data. Here it is...

In an all-day hearing, the agency’s scientists argued against allowing broad access to unproven drugs that the agency had banned three years ago.

This editorial contextualizes a randomized trial of interval likelihood ratios for clinical decision-making.

Dichotomized reporting of diagnostic test results may oversimplify test characteristics. Interval likelihood ratios (ILRs), test characteristics across a range of values, offer a nuanced alternativ...

Addison's disease is a relatively common disorder to endocrinologists, but is rare and potentially fatal when presenting acutely. Treatment now involves replacement of glucocorticoids and mineralocort...

A 47-year-old man with heart failure with a reduced ejection fraction and an ICD for the primary prevention of sudden cardiac death presented with an unheralded syncopal event, which had been captu...

A recent federal announcement to combat tick-borne disease has a promising premise but deserves scrutiny.