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Sameer Sheth, MD, PhD

@sameershethmd.bsky.social
57 followers 43 following 11 posts

Neurosurgeon and Professor at Baylor College of Medicine

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Reposted by Sameer Sheth, MD, PhD
Nicole Rust @nicolecrust.bsky.social · 11/09/2026
The Grand Plan for brain & mind research is in terrific hands with the researchers at Baylor College of Medicine! From an excellent panel discussion across silos to many insightful conversations with PIs and trainees, I'm a bit blown away by what they are up to here. Impactful & exciting.
Poster for Reimagining Brain Therapies
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Reposted by Sameer Sheth, MD, PhD
From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 10/09/2026
Drs. @benhayden.bsky.social @sameershethmd.bsky.social @assiachericoni.bsky.social et al reveal how hippocampal #neurons track the positions of self, others, and gaze direction. @cp-neuron.bsky.social @bcmhouston.bsky.social @bcmneurosurgery.bsky.social @bcmneurosci.bsky.social tinyurl.com/29mxnz2n
cell.com
Neural geometry in the human hippocampus enables generalization across spatial position and gaze
Chericoni et al. show that neurons in the human hippocampus track the positions of multiple agents in a simple pursuit-based video game. They identified place codes for each agent and for gaze. The co...
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Reposted by Sameer Sheth, MD, PhD
Ben Hayden @benhayden.bsky.social · 09/09/2026
New paper from the Neurosurgery Research Team at BCM! “Neural geometry in the human hippocampus enables generalization across spatial position and gaze” led by @assiachericoni.bsky.social! 🧵 www.cell.com/neuron/abstr...
cell.com
Neural geometry in the human hippocampus enables generalization across spatial position and gaze
Chericoni et al. show that neurons in the human hippocampus track the positions of multiple agents in a simple pursuit-based video game. They identified place codes for each agent and for gaze. The co...
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Reposted by Sameer Sheth, MD, PhD
From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 03/09/2026
How does the #brain make decisions in real time? Check out the findings by A. Chericoni, B. Hayden, S. @sameershethmd.bsky.social et al. reported in @nature.com @bcmhouston.bsky.social @bcmneurosurgery.bsky.social blogs.bcm.edu/2026/09/03/m...
blogs.bcm.edu
Making decisions: how the human brain continuously balances competing goals in real time
Together, three brain regions enable the seamless balancing and updating of goals that allows us to navigate moment-to-moment decisions in the complex world around us.
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Reposted by Sameer Sheth, MD, PhD
From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 21/08/2026
How does the #brain navigate between competing #goals? B. Hayden, @sameershethmd.bsky.social et al explain their findings in @nature.com @bcmhouston.bsky.social @bcmneurosurgery.bsky.social #GPS #decissionMaking www.bcm.edu/news/beyond-...
bcm.edu
Beyond yes or no: How the brain navigates between competing goals
How do we decide what to do when faced with choices? And how does the brain adapt those decisions as the world around us changes? A new study published...
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Reposted by Sameer Sheth, MD, PhD
Ben Hayden @benhayden.bsky.social · 13/08/2026
New paper from the BCM Neurosurgery research team! "Neural basis of compositional control" led by @assiachericoni.bsky.social and @justfineneuro.bsky.social ! 🧵 www.nature.com/articles/s41...
nature.com
Neural basis of compositional control - Nature
Behaviour of human participants in a prey-pursuit task reflects dynamic blending of goal-specific control policies, with hippocampus estimating latent states, anterior cingulate cortex orchestrating p...
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Reposted by Sameer Sheth, MD, PhD
Eleonora Bartoli @elebartoli.bsky.social · 30/06/2026
New preprint from my lab, showing that OFC CCEPs may be able to predict antidepressants effects in DBS for depression! With @srheilbronner.bsky.social, @sameershethmd.bsky.social, @nicoleprovenza.bsky.social
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From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 06/07/2026
#Bilingual people appear to organize concepts in a shared neural structure when speaking different #languages. #brain @sameershethmd.bsky.social, B. Hayden, @xinyuanyan.bsky.social et al blogs.bcm.edu/2026/07/02/f... @cellpress.bsky.social @bcmhouston.bsky.social @bcmneurosurgery.bsky.social
blogs.bcm.edu
Scientists discover how the brain represents meaning across different languages
The findings may help explain how people can effortlessly translate thoughts between languages without confusing them.
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Reposted by Sameer Sheth, MD, PhD
Cell Press @cellpress.bsky.social · 24/06/2026
For many bilingual people, switching between languages feels effortless. Now, scientists have figured out how bilingual brains accomplish this feat at the single neuron level. spkl.io/633297EUXJ Xinyuan Yan, Benjamin, Y. Hayden, @sameershethmd.bsky.social & colleagues @cp-cell.bsky.social
first page of Cell paper: “Shared neural geometries for bilingual semantic representations in human hippocampal neurons"
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Reposted by Sameer Sheth, MD, PhD
Ben Hayden @benhayden.bsky.social · 24/06/2026
New lab paper ! "Shared neural geometries for bilingual semantic representations in human hippocampal neurons" led by @xinyuanyan.bsky.social. 🧵 www.sciencedirect.com/science/arti...
sciencedirect.com
Shared neural geometries for bilingual semantic representations in human hippocampal neurons
The human brain has the remarkable ability to comprehend and express similar concepts in multiple languages. To understand how it does so, we examined…
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Reposted by Sameer Sheth, MD, PhD
BCM Neurosurgery @bcmneurosurgery.bsky.social · 29/05/2026
#NEWS: A team at @bcmhouston.bsky.social & #RiceUniversity, which includes #BCMNeurosurgery's @sameershethmd.bsky.social & @nicoleprovenza.bsky.social, has joined #BrainGate, a consortium of universities and academic medical centers working on creating brain-computer interface (BCI) technologies 🧠
“It is a momentous step for Baylor and Rice to join BrainGate and lend our expertise to this consortium’s work. The development of an implant capable of allowing people to control a robotic arm holds the power to transform the lives of people living with paralysis, restoring not only movement but also independence and hope.”

-Sameer Sheth, M.D., Ph.D.
Baylor College of Medicine“Our team’s rich experience decoding mood, motivation and emotion from human intracranial neural recordings will hopefully enable improved control of motor and speech effectors. We are excited to explore how fluctuations in cognitive signals may impact the ability to control neuroprotheses long-term.”

-Nicole Provenza, Ph.D.
Baylor College of Medicine“My main research focus is building intracortical brain–computer interfaces, a rapidly expanding field, with the goal of helping people who are paralyzed and rely on care partners to restore independence in communication and activities of daily living.”

-Nishal Shah, Ph.D.
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Sameer Sheth, MD, PhD @sameershethmd.bsky.social · 29/05/2026
Excited to share our team @nicoleprovenza.bsky.social and I and @bhaishahster.bsky.social will be joining the BrainGate consortium! This clinical trial focuses on developing assistive robotic technologies for individuals with paralysis to help improve quality of life www.bcm.edu/news/clinica...
bcm.edu
Clinical Trial Seeks to Advance Intuitive Assistive Robotics for People with Paralysis
When a person loses a limb, a prosthesis often can help restore a significant degree of mobility. But when movement or communication is impaired by a neurological...
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Reposted by Sameer Sheth, MD, PhD
BCM Neurosurgery @bcmneurosurgery.bsky.social · 15/05/2026
“The brain has developed such amazing, sophisticated mechanisms for doing all these complex [language processing] tasks all day long, that it can do some of these things even without us being aware.” @sameershethmd.bsky.social explains more in a recent @nature.com article: tinyurl.com/2hf7jyn2
“The brain has developed such amazing, sophisticated mechanisms for doing all these complex [language processing] tasks all day long, that it can do some of these things even without us being aware.”

-Sameer Sheth, M.D., Ph.D.
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Reposted by Sameer Sheth, MD, PhD
From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 19/05/2026
Baylor College of Medicine recognizes #research excellence with #DeBakey Awards. @bcmhouston.bsky.social S. Hartig, Z. Liu, R. Kommagani, A. Lee and @sameershethmd.bsky.social @bcmneurosurgery.bsky.social blogs.bcm.edu/2026/05/19/f...
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Reposted by Sameer Sheth, MD, PhD
BCM Neurosurgery @bcmneurosurgery.bsky.social · 26/05/2026
#ICYMI: #BCMNeurosurgery's @sameershethmd.bsky.social and @benhayden.bsky.social are featured in Time, discussing their recent findings which suggest that the #brain is still capable of complex language processing, even while unconscious 🧠 Read more: tinyurl.com/mrxr753z
tinyurl.com
The Brain Processes Language Even Under Anesthesia, a New Study Finds
It’s further proof that even fairly complex neural processes are not the same as consciousness.
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Reposted by Sameer Sheth, MD, PhD
From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 28/05/2026
Baylor @bcmhouston.bsky.social, @riceuniversity.bsky.social join #BrainGateTeam to create #brainComputerInterface technologies that assist people with impaired #movement. @sameershethmd.bsky.social @nicoleprovenza.bsky.social N. Shah @neuroleigh.bsky.social M. Norton www.bcm.edu/news/clinica...
bcm.edu
Clinical Trial Seeks to Advance Intuitive Assistive Robotics for People with Paralysis
When a person loses a limb, a prosthesis often can help restore a significant degree of mobility. But when movement or communication is impaired by a neurological...
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Sameer Sheth, MD, PhD @sameershethmd.bsky.social · 13/05/2026
Please welcome Marie Vallens, our new PhD student in QCB at BCM! Her BS in Physics (Biomedical) from Portland State, MS in Bioinformatics (Neuroinformatics) from JHU, and prior computational clinical neurotech experience inform her work in our lab on semantic encoding in the PFC.
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Sameer Sheth, MD, PhD @sameershethmd.bsky.social · 13/05/2026
Welcoming BCM QCB PhD student Minye Zhou to the lab! She earned her B.S. in Bioinformatics from UC San Diego and M.S. in Computational Biology & Quantitative Genetics from Harvard. Her research focuses on how the brain integrates multimodal inputs to support natural behavior.
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Reposted by Sameer Sheth, MD, PhD
Ben Hayden @benhayden.bsky.social · 06/05/2026
New paper from the lab! "Plasticity and language in the anaesthetized human hippocampus" www.nature.com/articles/s41...
nature.com
Plasticity and language in the anaesthetized human hippocampus - Nature
In the hippocampus, complex processing of sensory stimuli occurs even in the unconscious state.
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Reposted by Sameer Sheth, MD, PhD
From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 06/05/2026
The #humanBrain is capable of sophisticated #language processing while in an unconscious state from general #anesthesia. @sameershethmd.bsky.social, B Hayden et al explain their findings. @nature.com @bcmhouston.bsky.social @bcmneurosurgery.bsky.social www.bcm.edu/news/researc...
bcm.edu
Researchers discover advanced language processing in the unconscious human brain
Baylor College of Medicine researchers have found that the human brain is capable of sophisticated language processing while in an unconscious state from...
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Reposted by Sameer Sheth, MD, PhD
BCM Neurosurgery @bcmneurosurgery.bsky.social · 27/04/2026
#NEWS: Motif Neurotech, a brain-computer interface (BCI) company co-founded by @sameershethmd.bsky.social, has received FDA approval for a first-in-human study to evaluate its Motif XCS System, offering hope for individuals living with treatment-resistant depression 🧠 → tinyurl.com/2v7txufr
“Treatment-resistant depression is one of the leading causes of disability and suicide in the U.S. and worldwide. Individuals with this condition have often tried a long list of medications and therapies and are still suffering. The RESONATE study gives us the opportunity to offer something genuinely new to people who have run out of options.”

Sameer Sheth, M.D., Ph.D.
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Reposted by Sameer Sheth, MD, PhD
BCM Neurosurgery @bcmneurosurgery.bsky.social · 17/04/2026
#NEWS: @sameershethmd.bsky.social has been named as one of this year's recipients of the prestigious @bcmhouston.bsky.social Michael E. DeBakey, M.D., Excellence in Research Award! The honor recognizes outstanding scientific contributions over the past three years. #BCMNeurosurgery
Sameer Sheth, M.D., Ph.D., has been named of the recipients of the prestigious Baylor College of Medicine Michael E. DeBakey, M.D., Excellence in Research Award.
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Sameer Sheth, MD, PhD @sameershethmd.bsky.social · 03/04/2026
Proud to share funding for our R01 (MH137102) as part of an outstanding MPI team, alongside Jennifer Blumenthal-Barby and Parag Patil. Looking forward to advancing this important work at the intersection of neuroscience, ethics, and innovation. @bcmneurosurgery.bsky.social
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Reposted by Sameer Sheth, MD, PhD
Nicole Rust @nicolecrust.bsky.social · 27/03/2026
Excited to be posting updates from Brown today at this INCREDIBLE symposium organized by @wael-asaad.bsky.social+, focused on therapies for the most formidable conditions: depression, OCD, severe autism, disorders of consciousness & memory.
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Sameer Sheth, MD, PhD @sameershethmd.bsky.social · 20/03/2026
Congratulations to this outstanding team—our project on reward sensitivity through a cross-species circadian lens has been selected for funding. @nicoleprovenza.bsky.social @bcmneurosurgery.bsky.social
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Sameer Sheth, MD, PhD @sameershethmd.bsky.social · 20/03/2026
Congratulations to these med students who did a research year in our BCM Neuromodulation group and matched today! Very proud of all of you!! Wishing you great success in your training! Gabriel Reyes, Anthony Allam, Zain Naqvi, Kasra Mansourian, Davin Devara, Holden Bentley.
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Sameer Sheth, MD, PhD @sameershethmd.bsky.social · 09/03/2026
Excited to share our latest work in Operative Neurosurgery on using a combination procedure of open resection and responsive neurostimulation (RNS) for epilepsy. journals.lww.com/onsonline/fu... @bcmneurosurgery.bsky.social
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Sameer Sheth, MD, PhD @sameershethmd.bsky.social · 04/03/2026
Great presentation today with neurosurgeon Jon Willie from @uthealthaustin.bsky.social at the @riceneuro.bsky.social Engineering Minds seminar, highlighting exciting work on amygdala neuromodulation for memory enhancement and PTSD.
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Sameer Sheth, MD, PhD @sameershethmd.bsky.social · 02/03/2026
What a pleasure to welcome Flip Sabes to BCM last week for a fascinating look at next-gen neuromodulation and the interface of academia and neurotech! @nicoleprovenza.bsky.social @benhayden.bsky.social @bcmneurosci.bsky.social @bcmneurosurgery.bsky.social
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Reposted by Sameer Sheth, MD, PhD
Marcin Leszczynski @marcin-leszcz.bsky.social · 27/09/2025
1/3: What happens in the #brain when moving your eyes? Using closed-loop #EyeTracking with simultaneous intracranial #EEG in humans, we found that: *Saccades boost visual responses but reduce network connectivity. *Excitability changes and visual features are coded along the saccade–fixation cycle.
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Reposted by Sameer Sheth, MD, PhD
Anup Das, PhD @neuroanup.bsky.social · 18/09/2025
1/7 New preprint on the role of insular traveling waves in memory and behavior, using depth recordings from neurosurgical patients, with @chenwumd.bsky.social, Sameer Sheth, and Josh Jacobs. www.biorxiv.org/content/10.1...
biorxiv.org
Insular Traveling Waves Link Distributed Neural Dynamics to Human Memory Performance
The insula is a critical brain region that plays a foundational role in adaptive human behaviors, with diverse subregions performing distinct functional roles. However, explaining how these insular su...
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