Sign in

Samaneh Ch

@samanehcha64.bsky.social
466 followers 2.4K following 14 posts

Microbiology

PostsRepliesMedia
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 16/09/2026
www.businesswire.com/news/home/20.... Here is a new Mass spec to structure challenge for #metabolomics $50K in prizes.
businesswire.com
074 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 17/09/2026
I am a fan of reading papers where a few people had such deep thought to create a written piece of art but this paper below might become the demise of the concept of a paper altogether and questions why papers are needed at all - such a crazy time we live in. www.nature.com/articles/s41...
nature.com
Reimagining research papers as interactive and reliable AI agents - Nature
Paper2Agent converts research papers into interactive artificial intelligence agents by turning manuscripts, code and data into model context protocol-based tool-invoking systems that reproduce origin...
152 0
Samaneh Ch @samanehcha64.bsky.social · 12/06/2026
000 0
Reposted by Samaneh Ch
UC San Diego Health Sciences @ucsdhealthsci.bsky.social · 13/05/2026
A new web tool called #StructureMASST lets anyone search the world’s public #metabolomics data by chemical structure. #Pharmacy #BigData #SearchEnginge @ucsdpharmacy.bsky.social @pieterdorrestein.bsky.social buff.ly/NXH5r3f
today.ucsd.edu
From Molecules to Meaning: A Search Engine for the Chemistry of Life
A new web tool called StructureMASST lets anyone search the world’s public metabolomics data by chemical structure.
086 0
Reposted by Samaneh Ch
Yasin El Abiead @yelabiead.bsky.social · 16/04/2026
Where has this molecule been detected before across samples, organisms, body parts, and environments? With StructureMASST, you can explore this directly by entering a molecule name and running a search in your browser. 🔗 structure-masst.gnps2.org 📄 www.nature.com/articles/s41...
structure-masst.gnps2.org
Streamlit
32610 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 16/04/2026
Extracting information pan-repositories using structures or substructures have just become possible - see terrific thread by Yasin below.
0122 0
Reposted by Samaneh Ch
Daan Speth @daanspeth.bsky.social · 21/11/2025
Our paper describing the GlobDB is now published in @bioinfoadv.bsky.social doi.org/10.1093/bioa... The GlobDB is the largest species dereplicated genome database currently available, containing 306,260 species representatives. More information on globdb.org 1/5 🖥️🧬🦠
doi.org
GlobDB: a comprehensive species-dereplicated microbial genome resource
AbstractMotivation. Over the past years, substantial numbers of microbial species’ genomes have been deposited outside of conventional INSDC databases.Resu
28944 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 05/03/2026
Yet another new function of bile acids -and relevance of the microbiome in regulating the efficacy of medications. #microbiome #IBD. Discovered using #metabolomics repository scale analysis. #opendata Thanks to all the collaborators and Vincent for leading it. www.biorxiv.org/content/10.6...
biorxiv.org
0194 0
Reposted by Samaneh Ch
Daniel Petras @daniel-petras.bsky.social · 07/02/2026
I am super excited that our paper on inter-laboratory comparability of non-targeted LC–MS/MS analysis of dissolved organic matter was just published in ES&T. pubs.acs.org/doi/10.1021/...
6176 0
Reposted by Samaneh Ch
Laura MATHIEU @lauramathieu.bsky.social · 05/02/2026
nph.onlinelibrary.wiley.com/doi/10.1002/...
nph.onlinelibrary.wiley.com
Inspiring the next generation of plant scientists: What we learned from 421 plant biologists
Addressing biodiversity and climate crises requires a new generation of plant scientists, yet interest in plant-related careers is declining globally. A survey of 421 plant biologists revealed that t...
031 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 12/12/2025
The best keychain ever - ty. This was a molecule discovered in this work www.cell.com/cell/fulltex... . To Prof. Ipsita - I can’t wait to see what you will discover in your own lab at Penn State. Such a pleasure to have had you as a co-worker in the lab. @ipsitamohanty.bsky.social
cell.com
The underappreciated diversity of bile acid modifications
Using mass spectrometry-based tools to mine public untargeted MS/MS data revealed the vastly underappreciated diversity of bile acids hidden in plain sight and led to the discovery of previously unkno...
2232 0
Samaneh Ch @samanehcha64.bsky.social · 14/12/2025
020 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 07/12/2025
This is an important paper to read for people that are trying to understand metabolomics data. Ions detected (features) are not molecules and molecules will generate many ion forms. Be aware of MS ion forms - understand and leverage them. Dark metabolome has a lot of discovery potential.
1218 0
Reposted by Samaneh Ch
British Mycological Society @britmycolsoc.org.uk · 28/11/2025
Cryptococcus neoformans is responsible for nearly 200,000 deaths per year - more than any other fungal pathogen. In this talk, Caroline Coelho describes development of a large-scale imaging platform to investigate host-pathogen interactions 👉 Book here: www.britmycolsoc.org.uk/bms-talks.html
Photo of Carolina Coelho, and the text "BMS Talk 10 December 2025 19:30-21:00. Crossing the line: visualising how Cryptococcus neoformans breaches host tisue barriers from lung to brain."
161 0
Samaneh Ch @samanehcha64.bsky.social · 27/11/2025
#mushroom #lichen #wood #lovely_fungi
060 0
Samaneh Ch @samanehcha64.bsky.social · 27/11/2025
😍😍😍#mushrooms
170 0
Reposted by Samaneh Ch
Natural Product Reports @natprodreports.rsc.org · 19/11/2025
We are delighted to sponsor the Natural Products in the 'Omics Era' symposium at @pacifichem.bsky.social! Keynote speakers include @pieterdorrestein.bsky.social whose research focuses on new MS-based methods to understand the chemistry of microbes #ORG018 📅19-20 December 2025 🔗pacifichem.org
0103 0
Reposted by Samaneh Ch
Microbetv @microbetv.bsky.social · 16/11/2025
@markowenmartin.bsky.social shares how his students test moss- and lichen-derived bacteria for antibiotic activity, using Micrococcus luteus as a control Except from Matters Microbial 116: Microbes in the Concrete Instead of the Abstract
0112 0
Samaneh Ch @samanehcha64.bsky.social · 09/11/2025
020 0
Reposted by Samaneh Ch
The MRC Centre for Medical Mycology @mrccmm.bsky.social · 04/11/2025
🚨 CMM LATAM Unit website is now live 🚨 Explore the CMM LATAM unit, established by University of São Paulo, Brazil and the MRC Centre for Medical Mycology (CMM). 🌍 Explore cutting edge research 🎓 Discover funding and training opportunities 🛡️ Join the FAILSAFE network cmm-latam.com
143 0
Reposted by Samaneh Ch
BioMassSpec @realbiomassspec.bsky.social · 01/11/2025
From Mass to Class: Classification of Amphetamines MS/MS Spectra via Graph Neural Networks #JCIM pubs.acs.org/doi/10.1021/...
pubs.acs.org
From Mass to Class: Classification of Amphetamines MS/MS Spectra via Graph Neural Networks
Identifying emerging novel psychoactive substances (NPS), using liquid chromatography high-resolution tandem mass spectrometry (LC-HR-MS/MS), is often hindered by their frequent absence from mass spec...
052 0
Reposted by Samaneh Ch
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 29/10/2025
Cool 🦠 William Schmidt Gerard Wong Lab @UCLA Nature Microbiology Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode
nature.com
Pseudomonas aeruginosa senses exopolysaccharide trails using type IV pili and adhesins during biofilm formation - Nature Microbiology
Opposing forces generated by exopolysaccharide trail binding versus type IV pilus retraction generate a high cyclic diGMP–high cyclic AMP state in Pseudomonas aeruginosa that promotes social motility.
0208 0
Reposted by Samaneh Ch
BioMassSpec @realbiomassspec.bsky.social · 15/10/2025
Analysis of bioactive compounds in Gardenia jasminoides from different regions by UFLC/QTRAP-MS and PCA #Medicine journals.lww.com/md-journal/f...
journals.lww.com
021 0
Samaneh Ch @samanehcha64.bsky.social · 15/10/2025
000 0
Reposted by Samaneh Ch
BioMassSpec @realbiomassspec.bsky.social · 07/09/2025
HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics #Cell #MassSpec www.cell.com/cell/fulltex...
cell.com
HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics
Single-cell metabolomics (SCM) can probe metabolic heterogeneity but is hindered by low sensitivity for small molecules, limited scalability, and the lack of standardized frameworks for data analysis....
053 0
Reposted by Samaneh Ch
Marnix Medema @marnixmedema.bsky.social · 08/09/2025
We are looking for a 3-year postdoc to work with Daniel Probst, Justin van der Hooft and myself on an exciting project involving federated learning and integrative omics for discovery of new antibiotics from natural products. Apply here: www.wur.nl/en/vacancy/p... Please share!
wur.nl
13232 0
Samaneh Ch @samanehcha64.bsky.social · 07/09/2025
010 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 05/09/2025
It started with a concept of using data science and mass spectrometry for drug discovery with the goal to help people improve quality of their lives enveda.com. Now it’s a 🦄 that is getting a real shot at doing so with great clinical leads and in clinical trials www.youtube.com/watch?v=VafS....
enveda.com
Home
171 0
Reposted by Samaneh Ch
Yasin El Abiead @yelabiead.bsky.social · 26/08/2025
Interested in a co-authorship? We’re building a tool for repository-scale untargeted #metabolomics and #exposomics of #environmental data. To make it the best it can be, we’re looking for people willing to share high-resolution LC-MS/MS (DDA) data from #water, #soil, #sediment, and related samples.
31613 0
Reposted by Samaneh Ch
Rachel Gregor @rachelgregor.bsky.social · 25/08/2025
🌊🦠🧪 Delighted to share this work now out in @isme-microbes.bsky.social: doi.org/10.1093/isme... The currency of microbial life is chemistry, but there’s so much still unknown about how metabolic interactions shape communities. 1/
doi.org
Vitamin auxotrophies shape microbial community assembly on model marine particles
Abstract. Microbial community assembly is governed by the flow of carbon sources and other primary metabolites between species. However, central metabolism
12917 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 26/08/2025
Yes reach out to Yasin for this project. It will allow a worldwide picture of the environmental metabolome. This can be already published or not yet published data but will need world coordinates.
2115 0
Reposted by Samaneh Ch
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 18/08/2025
🄰 🄿🅁🄾🄱🄸🄾🅃🄸🄲 🄵🄾🅁 🅂🅃🅁🄾🄺🄴 🅁🄴🄲🄾🅅🄴🅁🅈 ?? Low 𝘓𝘢𝘤𝘵𝘰𝘣𝘢𝘤𝘪𝘭𝘭𝘶𝘴 𝘢𝘤𝘪𝘥𝘰𝘱𝘩𝘪𝘭𝘶𝘴 levels in the gut predicted cognitive decline after ischemic stroke Probiotic supplementation improved cognition in mice + human clinical trial by ↑ linoleic acid uptake → microglial peroxisomes → anti-inflammatory reprogramming
cell.com
Lactobacillus acidophilus promotes cognitive function recovery via regulating microglial peroxisomal function in cerebral ischemia
Huang et al. report that L. acidophilus deficiency correlates with cognitive decline in cerebral ischemia patients. In cerebral ischemia mouse models, L. acidophilus supplementation enhances linoleic ...
0141 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 13/08/2025
The best of both worlds with awesome speakers that will focus on how the microbiome affects ecosystems at a mechanistic level. Can’t wait for this meeting.
0122 0
Reposted by Samaneh Ch
Nature Microbiology @natmicrobiol.nature.com · 08/08/2025
#NatMicroPicks Hidden microbial world in trees🌳 Living wood hosts trillions of bacteria making trees a complex ecosystems with major roles in forest health and function. #PlantMicro #MicroSky www.nature.com/articles/s41...
nature.com
A diverse and distinct microbiome inside living trees - Nature
Microbiome analyses of living trees show that a single tree can host approximately one trillion bacteria, with microbial communities distinctly partitioned between heartwood and sapwood and with minim...
07529 0
Reposted by Samaneh Ch
Titus Brown @titus.idyll.org · 08/08/2025
taxburst v0.3.0 is now released - this is an update of the Krona visualization system for microbiome/metagenome taxonomy analyses. Enjoy!
ivory.idyll.org
Announcing taxburst, an update of the Krona software for taxonomy exploration
Announcing taxburst for metagenome taxonomy!
02617 0
Reposted by Samaneh Ch
Dr Katherine Duncan @kateduncan.bsky.social · 08/08/2025
www.annualreviews.org/content/jour...
annualreviews.org
Roles of Marine Microbial Natural Products | Annual Reviews
Over billions of years, marine microorganisms evolved a vast genetic potential to produce the molecules we denote as natural products or secondary metabolites. While these molecules show promise as th...
052 0
Reposted by Samaneh Ch
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 07/08/2025
Please share my 1 min video on the importance of maintaining NIH funding of infectious diseases and drug discovery research vs rising antibiotic resistance Drastic budget cuts harm our health and imperil the next generation of scientists More @UCSanDiego “Behind Every Breakthrough” bit.ly/3FlXQs3
39671 0
Samaneh Ch @samanehcha64.bsky.social · 31/07/2025
110 0
Reposted by Samaneh Ch
Daniel Petras @daniel-petras.bsky.social · 27/07/2025
New paper from the group. Together with Chambers Hughes, Giovanni Vitale and our amazing collaborators, we developed a multiplexed chemical metabolomics workflow to assign functional groups in non-targeted LC-MS/MS data: www.nature.com/articles/s41... Behind the paper story: go.nature.com/45ljV4d
nature.com
Enhancing tandem mass spectrometry-based metabolite annotation with online chemical labeling - Nature Communications
To improve annotation in non-targeted metabolomics studies, authors develop a Multiplexed Chemical Metabolomics (MCheM) platform, combining post-column derivatization with integrated data processing. ...
33814 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 21/07/2025
I am so excited about this meeting. I will cover the discovery of 10,000s new metabolites, including an entirely new class of molecules. Looking forward to hearing and discussing your science on microbiome metabolites and metabolism.
0317 0
Reposted by Samaneh Ch
Dr Katherine Duncan @kateduncan.bsky.social · 21/07/2025
www.theguardian.com/society/2025...
theguardian.com
Superbugs could kill millions more and cost $2tn a year by 2050, models show
Exclusive: Research on burden of antibiotic resistance for 122 countries predicts dire economic and health outcomes
043 0
Reposted by Samaneh Ch
Dr Katherine Duncan @kateduncan.bsky.social · 15/06/2025
Wonderful to have Prof Pieter Dorrestein @pieterdorrestein.bsky.social giving the opening keynote talk of #ISBA2025 on ‘Scaling the discovery of new microbial natural products through data science of unused metabolomics data’ #naturalproducts #specializedmetabolites #secmet
1312 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 02/07/2025
Sometimes one get’s to see results that just blow your mind and know instantly how impactful and transformative it is. Probably just got send by a post doc one of the most exciting results I have seen in my career - I LOVE science!! Paper will be hard to write but so fun and just wow.
2122 0
Reposted by Samaneh Ch
Kyo Bin Kang @kyobinkang.bsky.social · 22/06/2025
In this article published today in @metabolomicsj.bsky.social, we introduce the Korea MetAbolomics data rePository (KMAP), and describe what our team has pushed hard and what we will do, to make it standardized and harmonized with the other data repository. doi.org/10.1007/s113...
doi.org
Introducing Korea metabolomics data repository (KMAP): bridging Korean metabolomics data to global data sharing infrastructure - Metabolomics
The Korea MetAbolomics data rePository (KMAP), available at https://kbds.re.kr/KMAP , is a public repository for metabolomics datasets developed as a part of the Korea BioData Station (K-BDS). KMAP ar...
0103 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 12/06/2025
If you have ever wondered what might happen to short chain fatty acids made by the microbiome. Here is a large class of metabolites and how they link to biology. www.cell.com/cell/fulltex...
cell.com
The microbiome diversifies long- to short-chain fatty acid-derived N-acyl lipids
Mass spectrometry data mining tools enabled the creation of an MS/MS spectral library containing hundreds of N-acyl lipids, including conjugates with short-chain fatty acids. This resource enabled the...
29341 0
Reposted by Samaneh Ch
Justin J.J. van der Hooft @jjjvanderhooft.bsky.social · 12/06/2025
www.linkedin.com/posts/jjjvan...
linkedin.com
Thanks for the highlight MAGic-MOLFUN 😎 - it is a great honor to work with so many talented early-career researchers to enhance computational genomics and metabolomics workflows, to also improve… | Ju...
Thanks for the highlight MAGic-MOLFUN 😎 - it is a great honor to work with so many talented early-career researchers to enhance computational genomics and metabolomics workflows, to also improve integ...
011 0
Reposted by Samaneh Ch
EMN Metabolomics Society @emn-metsoc.bsky.social · 10/06/2025
Join us at Metabolomics 2025 for our workshop -> W10: EMN – MetaboMentors! Grow as a mentor or mentee through insights, tools & global perspectives. 📅 Monday, June 23rd, 8:15 - 10:15 in South Hall 2 🔗 www.metabolomics2025.org/workshops 🎤 #EMN #MetaboMentors #Mentorship #Metabolomics2025
077 0
Reposted by Samaneh Ch
BioMassSpec @realbiomassspec.bsky.social · 03/06/2025
Native Mass Spectrometry Facilitates Hit Validation in DNA-Encoded Library Technology #AngewChem onlinelibrary.wiley.com/doi/abs/10.1...
onlinelibrary.wiley.com
Native Mass Spectrometry Facilitates Hit Validation in DNA‐Encoded Library Technology
DNA-encoded Libraries (DEL) are increasingly used for small molecule drug discovery. While millions to billions of compounds can simultaneously be screened, the following validation of hits represent...
041 0
Reposted by Samaneh Ch
BioMassSpec @realbiomassspec.bsky.social · 03/06/2025
Comparative analysis of continuous similarity measures for compound identification in mass spectrometry-based metabolomics #CILS www.sciencedirect.com/science/arti...
sciencedirect.com
Comparative analysis of continuous similarity measures for compound identification in mass spectrometry-based metabolomics
In mass spectrometry (MS)-based metabolomics, the most straightforward and efficient approach for compound identification is the comparison of similar…
052 0
Reposted by Samaneh Ch
Pieter Dorrestein @pieterdorrestein.bsky.social · 30/05/2025
It’s so nice that an important paper led by yasin - is out. www.nature.com/articles/s41.... This paper is a key milestone as it is the foundation for data science across data repositories through indexing and metadata harmonization of 1.6 million files (although much more now due to updates). 1/n
2207 0