Statins, which are commonly prescribed to lower cholesterol, could help protect the eyes against glaucoma, says new research from UC San Diego.

New UC San Diego study finds psilocybin use among those with depression doesn't lead to abandoning traditional care but is linked to higher perceived unmet mental health needs.

Chronic back pain flares activate the brain's

A new grant awarded to UC San Diego and the University of Vermont will enable the construction of a national biological observatory, which will empower new discoveries in neurosciences and basic…

UC San Diego researchers have received a $12.6 million award from the National Institute on Drug Abuse to establish the Polysubstance Addiction Research Center, a multidisciplinary center designed to…

Researchers from UC San Diego found that a 12-month exercise intervention was associated with improvements in attention and memory among breast cancer survivors, while a companion analysis suggests…

A new UC San Diego study finds that an estimated 8.9% of adults age 65 and older used cannabis in the past year, and more than one in 10 of those who used cannabis met criteria for cannabis use…

Reinventing surgery, medical training and patient care — before patients even enter the room.

UC San Diego researchers find naturally occurring peptide catestatin reduces tau and amyloid buildup, eases brain inflammation and improves function in preclinical models of neurodegeneration.…

UC SanDiego researchers are using AI and

A new UC San Diego and San Diego VA study has found that U.S. Marines with higher natural anti-NMDAR1 antibody levels had ~25% lower depression and 22% lower PTSD symptoms after traumatic brain…

How artificial intelligence and geofences can reduce risk for drivers.

Academic medicine can lead the next era of innovation and artificial intelligence in health care.

Artificial intelligence accelerates drug innovation at UC San Diego.

Researchers at UC San Diego have demonstrated that one of biology’s most essential enzymes can accurately read and transcribe an expanded genetic alphabet containing eight DNA letters instead of the…

Researchers at UC San Diego have been awarded a DARPA contract to redesign red blood cells to temporarily boost human performance.

In this issue of Discoveries magazine, we explore the digital transformation across UC San Diego Health Sciences — through stories of breakthrough technologies, ethical frontiers and inventive…

UC San Diego study links higher Valley fever rates to some natural landscapes and agricultural land uses, raising concerns as drought and water regulations lead to more farmland being left…

Researchers identified a previously overlooked pattern of DNA mutations in colorectal cancer. The pattern had been detected in large cancer-genome datasets before, but researchers had interpreted it…

UC San Diego has launched Brain-FRAMe, an innovative program integrating neuroscience and immunology to improve brain health and clinical care for people living with HIV and methamphetamine use…

Working memory is essential to our daily functioning, but there are still unanswered questions about how it works. UC San Diego researchers are helping answer them.

UC San Diego researchers have found a

The Stein Institute for Research on Aging at UC San Diego will play a central role in an ambitious competition aimed at extending the human healthspan.

A mindfulness-based treatment for opioid use disorder could generate $12 in economic benefit for every dollar spent, a massive improvement on current approaches.

Researchers from University of California San Diego have found that switching to a vegan diet for just one month can alter the body’s epigenetic landscape in ways associated with reduced inflammation…

At the U.S. News & World Report Healthcare of Tomorrow conference, leaders from UC San Diego and from across the health care industry gathered in Washington, D.C., to explore a defining question: How…

Researchers from UC San Diego analyzed the latest data from one of the nation’s largest long-term studies of youth to better understand when substance use begins, how it changes during adolescence…

UC San Diego researchers and their colleagues designed short strands of DNA to target protein production by disease-causing mutations, dramatically reducing seizures and sparking developmental gains,…

New statewide analysis reveals rising injury severity among e-bike riders, particularly children, highlighting urgent needs for safety education, infrastructure improvements and policy changes.

The new Institute for Applied Health Intelligence at UC San Diego will connect resources across six schools and UC San Diego health to generate next-generation solutions for pressing challenges in…

Researchers at UC San Diego have developed a large-scale screening approach that identifies proteins controlling a fundamental step in gene expression known as alternative polyadenylation (APA). APA…

New research from UC San Diego suggests that an existing drug, previously shelved in other contexts, could help control cholesterol.

Innovative project will use AI-powered “digital twins” to help public health agencies better prevent HIV, hepatitis C and overdose among people who use drugs.

The grant provides continuing support for the Comprehensive Cancer Center’s cutting‑edge research and increases access to innovative cancer therapies across the San Diego region.

Using data from 1.5 million respondents in the Tobacco Use Supplement to the Current Population Survey, researchers created a “Willingness to Restrict Smoking” (WTRS) scale that captures how strongly…

New grants to UC San Diego researchers will help them explain why women are more likely to get Alzheimer's disease and develop new risk-prediction tools for clinicians.

A new training program at UC San Diego Moores Cancer Center is preparing scientists and physicians the ins and outs of industry, helping them bring promising ideas to patients faster.

UC San Diego researchers have identified genetic drivers of cocaine addiction, uncovering a potential new treatment target in the liver. This large-scale study maps how metabolism influences…

New research suggests that a single administration of spinal segment-targeted gene therapy may provide a long-lasting strategy for reducing muscle spasticity caused by spinal cord injury and…

A study of sea squirts from researchers at UC San Diego and their collaborators reveals new possibilities for regenerative medicine.

A study by UC San Diego researchers and their colleagues has found that semaglutide slows down the accumulation of biological aging markers in the DNA of adults with HIV, pointing to the potential of…

U.S. overdose death rates declined between 2023 and 2024, marking the first recorded drop in all four waves of the nation’s overdose crisis. However, overdose deaths involving stimulants without…

UC San Diego researchers discovered that blocking microRNA-25 reshapes the tumor immune environment and improves responses to cancer immunotherapy.

Researchers from UC San Diego have uncovered a new possibility for treating melanoma, and it's something we have in our bodies already.

A gene therapy approach developed by UC San Diego researchers could provide a fix for neurodegenerative diseases, including Alzheimer's and related dementias.

A new AI model developed by UC San Diego researchers could make it possible to predict treatment response based only on a tumor's genetics.

UC San Diego researchers report substantial reductions in symptoms of depression by using machine learning to tailor behavioral interventions based on data participants collect about their own moods…

Researchers from the University of California San Diego have found that women not only experience a higher burden of certain modifiable dementia risk factors, but also appear more vulnerable to their…

National study found use of the drug rose sharply following major media coverage and later White House promotion, despite limited large-scale evidence for autism treatment.

Sleep complaints may be an early warning sign of Alzheimer’s disease risk in older women. Sleep complaints may serve as a low-cost, early warning sign of Alzheimer’s risk and a potential target for…