Organoids and tissues grown from human cells promise more accurate results, with £20m Cambridge project to create standardised models

The UK government has agreed a deal with Donald Trump that will see the NHS pay pharma companies much higher drugs prices. This will cost the NHS £9 billion a year by 2036 – but so far the government ...

Our 2-day Science+ meeting, co-organised with Professor Geoff Pilkington on behalf of the Alliance for Human Relevant Science, was an exceptional experience. We were deeply honoured to have so many ou...

Science+ meeting organised by Professor Geoffrey J Pilkington, Ms Rebecca Ram, and Ms Kathy Archibald

On November 11th 2025, the UK Government published its long-awaited strategy, ‘Replacing animals in science’. Addressing both regulatory and ‘discovery’ research, it includes a range of measures to he...

The UK Government has (11.11.2025) published its strategy for “Replacing animals in science”, to deliver on a key pledge from the Labour Party’s election manifesto to set out a clear plan to reduce an...

The film ‘How to make drugs and feel great about everything’, by director Journey Wade-Hak and co-producer / writer Keegan Kuhn covers what will be familiar ground to many – the translational failure ...

When considering the use of animals in research intended to have relevance for human health, the time may come when we look back and realise that animal experiments have been a huge and costly distrac...

In our new paper, Safer Medicines Trust Research Director, Pandora Pound, explores whether a sociological perspective can help explain why animal research persists within academia despite the availabi...

The use of non-animal, new approach methodologies (NAMs) is increasing but there has been no associated decrease in animal use. Reasons may include th…

It's time for the UK to catch up and focus on modern, human-relevant science. Add your name to the petition calling on the government to create an ambitious and detailed roadmap to phase out animal te...

The government promised to work towards phasing out animal testing. Now they're creating a roadmap to make it happen, but it needs to be an ambitious and detailed plan, with clear milestones to drive ...

Recent developments in the US have taken us all by surprise, not only because they were unanticipated, but also due to their breadth and ambition. First the Food and Drug Administration (FDA) declared...

A cultural shift Much has been written about Nicole Kleinstreuer’s announcement in the joint workshop between the FDA and the National Institutes for Health (NIH), namely that all new NIH funding oppo...

May 20th every year marks Clinical Trials Day, to recognise the day in 1747 when James Lind, a ship’s surgeon in the British Royal Navy initiated what is considered to be one of the first ever clinica...

It all began on 10th April, when the US Food and DrugAdministration (FDA) announced its intention to take ‘a groundbreaking step to advance public health’ by using ‘more effective, human-relevant meth...

Andrei Georgescu of Vivodyne discusses key advantages of its humanized drug testing platform and the impact of the FDA’s policy shift.

Commentary: The Food and Drug Administration and the Environmental Protection Agency say they will start backing off of animal testing.

Summary of our recent publication on an intestine-on-chip model for gaining a deeper understanding of the pathogenicity mechanisms of Candida albicans.

A new biochip replicates key aspects of the PDAC microenvironment, providing a powerful tool for drug development and reduction of animal testing.

Science lobby prepares massive PR push against reduction strategy Science lobby prepares massive PR push against reduction strategy In the run-up...

A common misconception suggests that patients with severe illnesses support animal experiments in the hope of finding a cure. But the reality is different. Many patients are speaking out against the…

🐀 The capture of medicine by animal research and how to break free

Can a regulator make it as easy as possible for companies to market their products and at the same time protect the public health?

This blog explores established infection models using organ-on-chip technology and their implications for scientific research.

Objectives To investigate the drugs and indications that have passed through the UK's Early Access to Medicines Scheme (EAMS) to date, the type of evidence the ...

Australia’s lack of transparency and funding leave it on the outer as researchers worldwide explore alternatives for training, study and testing

Lawmakers detail shocking taxpayer-funded animal experiments, including drugged puppies, transgender lab rats, and gain-of-function research.

In the move to transition away from animal research and towards New Approach Methodologies (NAMs), the emphasis tends to be on developing and validating NAMs, as if their availability alone will creat...

A proposal to use the cosmetic animal testing bans as a legislative framework to advance safety standards in other areas, including medicines. Our Scientific Consultant, Rebecca Ram, is also a Scienti...

A comprehensive summary of internationally available courses on organ-on-chip technology, detailing the provider, content and location.