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Therapeutics Initiative (TI)

@drug-evidence.bsky.social
1.5K followers 1.4K following 708 posts

Independent, evidence-informed, practical #BetterPrescribing resources for physicians, pharmacists, & nurse practitioners. Based in the University of British Columbia's Faculty of Medicine, Department of Anesthesiology, Pharmacology & Therapeutics.

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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 09/10/2026
💭 How do prescribing patterns vary between older adults in their final year of life? A Canadian retrospective case-control study found community dwelling older adults with dementia had the highest rates of polypharmacy and hyperpolypharmacy: buff.ly/DAM9si4
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 10/10/2026
⚠️ ICYMI: UBC TI #BestEvidence webinar recording: Do your (es)citalopram prescriptions cost more than they're worth? 👉 youtube.com/watch?v=KWUi... #citalopram #escitalopram #prescribing #drugcosts
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Dr. Dionzie Ong: Do your (es)citalopram prescriptions cost more than they're worth?
YouTube video by Therapeutics Initiative
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 10/10/2026
ICYMI: TI #BestEvidence webinar recording! 🚨 #ADHD and other disability diagnoses: the seven sins of clinicians youtube.com/watch?v=P0Of... Speaker: Dr. Allyson Harrison #MedEd #diagnosis #BetterPrescribing #BetterHealth
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Dr. Allyson Harrison: ADHD and other disability diagnoses: the seven sins of clinicians
YouTube video by Therapeutics Initiative
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 08/10/2026
🚨 ICYMI - #Opioids prescribing webinar recording featuring pharmacologist Dr. David Juurlink 💊 What have we learned about #prescribing? 💊 How should we treat pain when opioids overdoses have become an intractable epidemic? 👉🏽 www.youtube.com/watch?v=dr46... #pain #MedEd #medsafety #deprescribing
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Dr. David Juurlink: Relieving pain in the era of fentanyl
YouTube video by Therapeutics Initiative
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 08/10/2026
ICYMI: UBC TI #Deprescribing series webinar #10 👉Watch the recording: ti.ubc.ca/deprescribin... Case: Less is S’more: Sweetening life by deprescribing in diabetes (and beyond) Presenter: Sydney Saunders, Primary Care Pharmacist #MedEd #diabetes
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 07/10/2026
‼️ ICYMI: We need to talk about #Tramadol 💊 ICYMI: Our #BestEvidence webinar recording featuring the TI's Dr. Jessica Otte Practical info for clinicians considering tramadol for pain: www.youtube.com/watch?v=Z_Gp... 👉 More here: ti.ubc.ca/letter131 #MedEd #deprescribing #pain
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Dr. Jessica Otte: We need to talk about tramadol
YouTube video by Therapeutics Initiative
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 06/10/2026
ICYMI - UBC TI #BestEvidence Webinar recording! "GLP-1 RA and SGLT2i in type 2 diabetes" Speaker: The TI's @guillaume-grenet.bsky.social 👉 View recording: youtu.be/JUCIfScMqGY #MedEd #CME #diabetes #CVD
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Dr. Guillaume Grenet: GLP-1 RA and SGLT2i in type 2 diabetes
YouTube video by Therapeutics Initiative
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 06/10/2026
💭 How do prescribing cascades contribute to problematic pharmacy and medication-related harm? A large retrospective cohort study from over 12,000 participants published in @lancetprimarycare.bsky.social provides valuable new insights: buff.ly/5ZMq4ph
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 06/10/2026
ICYMI - #Deprescribing webinar recording! 😍 When making decisions about 🛑 #statins, consider: ✅ patient values, preferences ✅ health status ✅ current evidence Watch as the TI's Dr. Wade Thompson summarizes current evidence: www.youtube.com/watch?v=cqEo... #MedEd
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Dr. Wade Thompson: Statin deprescribing for older adults
YouTube video by Therapeutics Initiative
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 01/10/2026
🚨ICYMI - our MOST-VIEWED new TI video in 2025: Addressing medications that are ineffective & potentially harmful for patients with alcohol & other substance use disorders 💊🍻🚬 ti.ubc.ca/harms-aud-sud/ Speaker: Dr. Evan Wood #alcohol #polypharmacy #BetterPrescribing
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Reposted by Therapeutics Initiative (TI)
Cochrane Hypertension @cochranehtn.bsky.social · 29/09/2026
🆕 #Cochrane Hypertension protocol 🆕 Blood pressure targets for hypertension in people with diabetes mellitus: doi.org/10.1002/1465... #hypertension #bloodpressure #diabetes
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 29/09/2026
Be sure to check out the next International Deprescribing Journal Club hosted by @deprescribeau.bsky.social! The journal club will be happening on October 1st at 09:00 AM Eastern Time (11:00 PM Australian Eastern Standard Time). Register using the QR code below!
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 28/09/2026
🚨 UBC TI #Deprescribing series webinar #10 👉Watch the recording: ti.ubc.ca/deprescribin... Case: Less is S’more: Sweetening life by deprescribing in diabetes (and beyond) Presenter: Sydney Saunders, Primary Care Pharmacist #MedEd #diabetes
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 27/09/2026
Our Statin Deprescribing Information Pamphlet was created specifically for older adult users of statins and their carers. This tool can be provided to help inform discussions with healthcare providers about continuing or stopping a statin. Download the information pamphlet here: buff.ly/Qw2tJOL
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 25/09/2026
🆕 UBC TI #Deprescribing series webinar #10 🆕 👉Watch the recording: ti.ubc.ca/deprescribin... Case: Less is S’more: Sweetening life by deprescribing in diabetes (and beyond) Presenter: Sydney Saunders, Primary Care Pharmacist #MedEd #diabetes
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 25/09/2026
🆕 UBC TI #Deprescribing series webinar #10 🆕 👉Watch the recording: ti.ubc.ca/deprescribin... Case: Less is S’more: Sweetening life by deprescribing in diabetes (and beyond) Presenter: Sydney Saunders, Primary Care Pharmacist #MedEd #diabetes @caden-recad.bsky.social @deprescribing.bsky.social
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 24/09/2026
Want to share the key points of our new #Statin #Deprescribing guideline with other healthcare providers, patients taking statins, or carers of statin-users? 💡 Check out our Statin Deprescribing Guideline Plain Language Summary! Download the resource here: deprescribing.org/resources/de...
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 24/09/2026
ICYMI: Examining #HbA1c in Frail Older Adults: A Linked Data Cohort Study www.ti.ubc.ca/2026/04/22/e... For frail people with #diabetes, there are important management lessons, including possibility that HbA1c isn't a useful metric & that #overtreatment with hypoglycaemic agents must be considered
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Reposted by Therapeutics Initiative (TI)
CADeN | ReCAD @caden-recad.bsky.social · 21/09/2026
🔍 A new @bmj.com study of 2.3M+ older adults in Ontario identified 24 ↑ priority potentially inappropriate prescribing cascades—where a medication side effect may lead to another medication being prescribed. The findings could help support medication review & deprescribing. 🔗 tinyurl.com/whwrz5ed
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Reposted by Therapeutics Initiative (TI)
CADeN | ReCAD @caden-recad.bsky.social · 22/09/2026
⏰ Reminder: Our 2026–27 Student Funding Program closes Sept. 30. Medical, pharmacy & nursing students can receive up to $500 CAD to lead peer education on medication appropriateness & deprescribing and spark new conversations. 💡Have a creative idea? Apply & bring it to life: tinyurl.com/yfxm9h32
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 15/09/2026
🤲 The wait is finally over - the full #Statin #Deprescribing Guideline published in Canadian Family Physician is finally here! The decision to stop a statin should be made together with the healthcare provider, the patient, and their carers. Read the full guideline here: buff.ly/ufS4HOv
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 23/09/2026
⌛️ TODAY (Sep 23) @ Noon Pacific ⌛️ UBC TI #Deprescribing webinar "Less is S’more: Sweetening Life by Deprescribing in Diabetes (and Beyond)" 👉 REGISTER: ti.ubc.ca/deprescribin... *** Up to 1.0 Mainpro+® Certified Activity credits #MedEd #CME #diabetes #BetterPrescribing
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 22/09/2026
⌛️ TOMORROW (Sep 23) @ Noon Pacific⌛️ UBC TI #Deprescribing webinar "Less is S’more: Sweetening Life by Deprescribing in Diabetes (and Beyond)" 👉 REGISTER: ti.ubc.ca/deprescribin... *** Up to 1.0 Mainpro+® Certified Activity credits #MedEd #CME #diabetes #BetterPrescribing
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 20/09/2026
Alongside the launch of our #Statin #Deprescribing Guideline, check out our new 3-Part Whiteboard Video series on our Youtube channel! Guideline and Algorithm Overview Video: buff.ly/7D0bei1 Case Example Videos: buff.ly/Oi9YQYZ buff.ly/0kM2jkm
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Introducing deprescribing.org's Statin Deprescribing Guideline and Algorithm
deprescribing.org’s evidence-based guidelines are tools to help you decide when and how to stop or reduce medications that may be causing harm or are no longer beneficial. This video introduces…
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 21/09/2026
🚨ICYMI: UBC TI #BestEvidence webinar recording Oral vs IV Antibiotics ti.ubc.ca/antibiotics-... See also: TI Therapeutics #antibiotics Letter ti.ubc.ca/letter155 Patient handout: When are oral ABX the right choice? ti.ubc.ca/antibiotics-...
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 18/09/2026
ICYMI: TI #BestEvidence webinar recording! 🚨 #ADHD and other disability diagnoses: the seven sins of clinicians www.youtube.com/watch?v=P0Of... Speaker: Dr. Allyson Harrison #MedEd #diagnosis #BetterPrescribing #BetterHealth
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Dr. Allyson Harrison: ADHD and other disability diagnoses: the seven sins of clinicians
YouTube video by Therapeutics Initiative
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 16/09/2026
#BetterPrescribing -> Better Health ❤️💪 Physician? Nurse Practitioner? Pharmacist? Researcher?👩🏾‍⚕️👨‍⚕️ ✅ Never miss another UBC Therapeutics Initiative webinar, workshop, publication ✅ SUBSCRIBE to our Therapeutics Letters + events: e1.envoke.com/ext/pages/af... #independent #MedEd
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Reposted by Therapeutics Initiative (TI)
CADeN | ReCAD @caden-recad.bsky.social · 01/09/2026
💊 Aging can change how our bodies respond to meds. When might the harms outweigh the benefits? Share this webinar with patients, caregivers, & communities: “Taking Medications Safely as You Age,” with pharmacist Louise Papillon-Ferland. 📅 Sept. 16 | 10–11:30 a.m. | 💻 Zoom 👉 tinyurl.com/2rfdb228
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Reposted by Therapeutics Initiative (TI)
CADeN | ReCAD @caden-recad.bsky.social · 14/09/2026
What makes a deprescribing recommendation more useful in practice? Join Shin Liau, PhD, from @monashuniversity.bsky.social on Oct. 1 to explore principles for integrating deprescribing into guidelines & strengthening recommendations. 🇦🇺 Hosted by @deprescribeau.bsky.social. 👉 tinyurl.com/m25yr3fw
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Reposted by Therapeutics Initiative (TI)
CADeN | ReCAD @caden-recad.bsky.social · 15/09/2026
Deprescribing diabetes meds doesn’t always go as planned. Join Sydney Saunders, primary care pharmacist at @novascotiahealth.bsky.social, Sept. 23, for @drug-evidence.bsky.social’s 10th Deprescribing Webinar “Less is S’more”—on monitoring, legacy ℞s & how to adapt if needed. 🔗 tinyurl.com/3zzmaywa
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 15/09/2026
🚨ICYMI - our MOST-VIEWED new TI video in 2025: Addressing medications that are ineffective & potentially harmful for patients with alcohol & other substance use disorders 💊🍻🚬 ti.ubc.ca/harms-aud-sud/ Speaker: Dr. Evan Wood #alcohol #polypharmacy #BetterPrescribing
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 12/09/2026
We collaborated with an international team of experts to create a Prioritized List of 24 Potentially Inappropriate Prescribing Cascades published in @bmj.com: www.bmj.com/content/394/... This list will help inform future prescribing and deprescribing initiatives. Please reshare w/ your network!
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 14/09/2026
ICYMI: TI #BestEvidence webinar recording youtu.be/vXhWbRXvGpM Dr. Davie Wong: Antimicrobial durations in practice: a product of magical thinking in medicine ✅ How we choose #antibiotics durations ✅ Recognize limitations of how we select durations ✅ Determining optimal duration #BetterPrescribing
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Dr. Davie Wong: Antimicrobial durations in practice - a product of magical thinking in medicine
YouTube video by Therapeutics Initiative
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 14/09/2026
🚨 ICYMI: UBC TI #ResearchMethods recording What is the role of regulatory documents & individual patient data in drug assessments? 👉 www.youtube.com/watch?v=LTk4... #medsafety #RIAT #OpenResearch #ResearchTransparency
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Dr. Juan Erviti: The need for access to regulatory documents for better drug assessment
YouTube video by Therapeutics Initiative
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 11/09/2026
🚨 Webinar: Audit & Feedback for Reducing Low-Value Testing Exploring how healthcare teams can: ✅ Reduce unnecessary testing ✅ Improve patient care ✅ Ensure efforts to ⬇️ unnecessary testing are fair+equitable 🗓️ Thu Sept 24 @ 9am Pacific ✍️ Register: bit.ly/46JwOFd #MedEd #LabTests #Overdiagnosis
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Welcome! You are invited to join a webinar: Rethinking Routine: Audit and Feedback for Reducing Low-Value Testing. After registering, you will receive a confirmation email about joining the webinar.
This webinar will explore how healthcare teams can reduce unnecessary tests and improve patient care using two practical approaches: audit and feedback, which helps clinicians understand and improve t...
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 01/09/2026
Find guidance on deprescribing benzodiazepines or opioids (when medically appropriate) on our Deprescribing Guidelines Repository (DEPOT) page: buff.ly/2Buy8U2
deprescribing.org
Deprescribing Guidelines Repository (DEPOT) - Deprescribing.org
A resource for guideline developers to share their guidelines and for guideline users to access deprescribing guidance. This public-facing central repository is a place where deprescribing guideline…
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 10/09/2026
🚨 UBC TI #Deprescribing webinar "Less is S’more: Sweetening Life by Deprescribing in Diabetes (and Beyond)" 👉 REGISTER NOW: ti.ubc.ca/deprescribin... *** Up to 1.0 Mainpro+® Certified Activity credits #MedEd #CME #diabetes #BetterPrescribing
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 09/09/2026
🚨ICYMI: UBC TI #BestEvidence webinar recording Safe & sound: #Polypharmacy & rational primary care ti.ubc.ca/drugevidence24 Dr. Dee Mangin describes key aspects of primary care in maximizing therapeutic benefit + provides examples/areas of challenge for rational tx
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 09/09/2026
Air Pollution 🏭 and Polypharmacy 💊. Is there any relation between the two? A recent systematic review and meta-analysis published in BMJ Public Health attempts to answer this question. Read the full study here: buff.ly/zbGS7s0
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Reposted by Therapeutics Initiative (TI)
Michael Sykes @msykes.bsky.social · 08/09/2026
🤩 This looks excellent!! 🤩 "Reducing Low-Value Testing" by two wonderful academics, Drs Nicola McCleary and Anshula Ambasta.
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 08/09/2026
🆕 Webinar: Audit & Feedback for Reducing Low-Value Testing Exploring how healthcare teams can: ✅ Reduce unnecessary testing ✅ Improve patient care ✅ Ensure efforts to ⬇️ unnecessary testing are fair+equitable 🗓️ Thu Sept 24 @ 9am Pacific ✍️ Register: bit.ly/46JwOFd #MedEd #LabTests #Overdiagnosis
bit.ly
Welcome! You are invited to join a webinar: Rethinking Routine: Audit and Feedback for Reducing Low-Value Testing. After registering, you will receive a confirmation email about joining the webinar.
This webinar will explore how healthcare teams can reduce unnecessary tests and improve patient care using two practical approaches: audit and feedback, which helps clinicians understand and improve t...
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 08/09/2026
#BetterPrescribing -> Better Health ❤️💪 Physician? Nurse Practitioner? Pharmacist? Researcher?👩🏾‍⚕️👨‍⚕️ ✅ Never miss another UBC Therapeutics Initiative webinar, workshop, publication ✅ SUBSCRIBE to our Therapeutics Letters + events: e1.envoke.com/ext/pages/af... #independent #MedEd
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 08/09/2026
BC family #physicians & NPs: Are you interested in reviewing + assessing your prescribing practices? 👩🏽‍⚕️👨🏼‍⚕️💊 Sign up to receive your confidential, personalized prescribing portrait from our TI Prescribing Portraits program: ti.ubc.ca/portrait #MedEd #PrescribingPortraits #BetterPrescribing
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 05/09/2026
🆕 BMJ DTB Editorial: Can we do more to address long-term harms of medicine use? Learning from the DES (diethylstilboestrol) disaster dtb.bmj.com/content/dtb/... "a drug’s legacy does not necessarily end at withdrawal; harmful effects can continue long after it is no longer in use" #drugsafety
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 04/09/2026
🆕 BMJ DTB Editorial: Can we do more to address long-term harms of medicine use? Learning from the DES (diethylstilboestrol) disaster dtb.bmj.com/content/dtb/... "a drug’s legacy does not necessarily end at withdrawal; harmful effects can continue long after it is no longer in use" #drugsafety
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 04/09/2026
BC family #physicians & NPs: Are you interested in reviewing + assessing your prescribing practices? 👩🏽‍⚕️👨🏼‍⚕️💊 Sign up to receive your confidential, personalized prescribing portrait from our TI Prescribing Portraits program: ti.ubc.ca/portrait #MedEd #PrescribingPortraits #BetterPrescribing
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 04/09/2026
BC family #physicians & NPs: Are you interested in reviewing + assessing your prescribing practices? 👩🏽‍⚕️👨🏼‍⚕️💊 Sign up to receive your confidential, personalized prescribing portrait from our TI Prescribing Portraits program: ti.ubc.ca/portrait #MedEd #PrescribingPortraits #BetterPrescribing
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 03/09/2026
ICYMI: TI #BestEvidence webinar recording! 🚨 #ADHD and other disability diagnoses: the seven sins of clinicians www.youtube.com/watch?v=P0Of... Speaker: Dr. Allyson Harrison #MedEd #diagnosis #BetterPrescribing #BetterHealth
youtube.com
Dr. Allyson Harrison: ADHD and other disability diagnoses: the seven sins of clinicians
YouTube video by Therapeutics Initiative
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 02/09/2026
🚨 UBC TI #Deprescribing webinar "Less is S’more: Sweetening Life by Deprescribing in Diabetes (and Beyond)" 👉 REGISTER NOW: ti.ubc.ca/deprescribin... *** Up to 1.0 Mainpro+® Certified Activity credits #MedEd #CME #diabetes #BetterPrescribing
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Reposted by Therapeutics Initiative (TI)
deprescribing.org @deprescribing.bsky.social · 01/09/2026
August 31st was International Overdose Awareness Day! Benzodiazepines and opioids are among the most common medications involved in medication overdoses worldwide. 🌎 #Deprescribing can help reduce the risk of drug overdose. Learn more about Drug Overdose and spread the word: buff.ly/sSwLnVO
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