iiinova — where your digital self keeps evolving

Ryan Hoffman, PhD @ryanthescientist.bsky.social · 08/02/2026

My wife just asserted that Gollum was played by Benedict Cumberbatch, or whatever

Ryan Hoffman, PhD @ryanthescientist.bsky.social · 20/12/2025

In grad school a new postdoc will be hired onto your project. This postdoc will ask to collaborate. Its important you say yes.

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 14/10/2025

Happy PostDoc Appreciation Week 🫶

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 12/08/2025

Being a new postdoc is going from being an expert is what your PhD lab DID, to being an expert in what your postdoc lab WILL DO.

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 10/07/2025

Started my postdoc at the Institute for Psychedelics and Neurotherapeutics at UC Davis this week 🤙

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 15/06/2025

No Kings Protest in Santa Cruz was huge and all peaceful! I've lived here for 13 years and have never seen this kind of turnout for anything before. Im proud of my town! The fight against fascism is alive and well. Keep it up y'all! #nokings

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 14/06/2025

Heading to the No Kings Protest. Here's my sign #NoKings Kings belong in Guillotines

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Indivisible ❌👑 @indivisible.org · 09/06/2025

We will not cower, even in the face of Trump’s militarized escalation. On Saturday, we are going to rise up all across the country in defiance of this administration’s authoritarian agenda. Join the nationwide peaceful protests for No Kings Day: www.nokings.org?SQF_SOURCE=i...

(around an image of a map of No Kings events) NO KINGS JUNE 14 - NATIONWIDE DAY OF DEFIANCE nokings.org

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 02/05/2025

I defend my thesis tomorrow, wish me luck!

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 17/04/2025

Just thought of my thesis title! Shooting to send it off Monday 🙃

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 01/04/2025

Cracked 100pg on my thesis today and I'm starting to see the finish line

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 26/03/2025

My thesis just broke 20k words. The scary part is I still have a lot to cover

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 16/03/2025

If you see this, quote post with your green art 💚

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John Lukens @lukensjohnr.bsky.social · 14/03/2025

Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum: Neuron www.cell.com/neuron/fullt...

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Stand Up for Science! @standupforscience.net · 13/03/2025

A troubling moment for the next generation of scientists. UMass Chan Med School is rescinding dozens of PhD offers in biomedical sciences due to fears over federal research funding cuts. www.nbcboston.com/news/local/u...

nbcboston.com

UMass Chan rescinds admission for biomedical sciences PhD program amid funding concerns

UMass Chan Medical School is rescinding admission offers to candidates for its biomedical sciences PhD program over concerns about federal funding cuts.

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 12/03/2025

Ergonomics are important - keep it natural

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The Daily Show @thedailyshow.com · 11/03/2025

Get in loser, we're tanking the economy

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 11/03/2025

A single cup of t-SNE to start the morning 🧪🥼🔬🧫🧬🧠

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 07/03/2025

Nerds Against Nazis #standupforscience2025 UC Santa Cruz 🥼🧪🔬🧫🧬🧠

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 05/03/2025

A little orange on yellow to start the morning #bananaslug

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 05/03/2025

Support Nerds 🧪🥼🔬🧫🧬 Reject Nazis

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BWJones @bwjones.bsky.social · 05/03/2025

Trans… genic. Trans.. genic. Trans. genic. Trans.genic. Transgenic is the word and concept you are looking for.

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 24/02/2025

I am excited to announce that I will be a Postdoc with David Olson's Lab and the Institute of Psychedelics and Neurotherapeutics (IPN) at UC Davis later this summer! Here's a cool video of what I've been doing for the PhD

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 13/02/2025

So a grants to study - patient derived iPSCs bias towards forming blood brain barrier choroid plexus and its influence on the apical-basal polarization of cerebral cells in organoids - wouldn't be considered for federal funding because it uses words Trump / white supremacists / fascists find scary?

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Saeed Jones @theferocity.bsky.social · 06/02/2025

Universities — including the schools that most aggressively shut down student activism — are now fully panicking because the Trump administration is about to shut down all kinds of funding for research and more. Too bad they made it clear that their students shouldn’t speak up and speak out.

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News Eye @newseye.bsky.social · 26/01/2025

NEW: Trump is going to force Americans to pay more for coffee because Colombia refused to accept his deportation flights. He announces immediate 25% tariffs on all Colombian goods, rising to 50% next week. Diplomatic bullying of a supposed ally and economic self-harm. It’s Day 6.

A post from Donald Trump which says:
I was just informed that two repatriation flights from the United States, with a large number of Illegal Criminals, were not allowed to land in Colombia. This order was given by Colombia’s Socialist President Gustavo Petro, who is already very unpopular amongst his people. Petro’s denial of these flights has jeopardized the National Security and Public Safety of the United States, so I have directed my Administration to immediately take the following urgent and decisive retaliatory measures:

-Emergency 25% tariffs on all goods coming into the United States. In one week, the 25% tariffs will be raised to 50%.
-A Travel Ban and immediate Visa Revocations on the Colombian Government Officials, and all Allies and Supporters.
-Visa Sanctions on all Party Members, Family Members, and Supporters of the Colombian Government.

-Enhanced Customs and Border Protection Inspections of all Colombian Nationals and Cargo on national security grounds.

-IEEPA Treasury, Banking and Financial Sanctions to be fully imposed.

These measures are just the beginning. We will not allow the Colombian Government to violate its legal obligations with regard to the acceptance and return of the Criminals they forced into the United States!

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The New York Times @nytimes.com · 26/01/2025

Investigators are still trying to determine what started the Eaton fire, which raged through Altadena, California, and killed 17 people. A new video appears to show sparking on a power line near the origin of the blaze. www.nytimes.com/2025/01/26/u...

Power lines are suspended from metal towers across a scorched canyon, with houses on hillsides in the background. A headline reads: "New Video of Eaton Fire Raises More Questions for Power Company." Photo by Stephen Ross Goldstein for The New York Times.

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Dave Levitan @davelevitan.bsky.social · 24/01/2025

More from inside NIH: Per a source with knowledge, for all internal research (of which there is like $10 billion worth or so), ALL purchasing shut down as of yesterday. That means gloves, reagents, anything involved with lab work, which means a lot of that work will stop.

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God @thegodshow.com · 23/01/2025

Thou shalt accept that DEI didn't hold your career back -- you're just mid, bro.

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George Takei @georgetakei.bsky.social · 23/01/2025

Trump has deployed active military to help round up migrants and put them into detention camps. The military forced us out of our homes at gunpoint in 1942 because we were considered possibly disloyal Americans. They sent us to internment camps for four years. History is repeating. Pay attention.

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 23/01/2025

Anyone else feeling like this for the last few days? 🎨 And yeah, that's Trump colored brainrot, and that sh*ts leaking everywhere #horror #art #painting

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Ilan Schwartz @germhuntermd.bsky.social · 22/01/2025

Scientific advancements aside, this is economically irresponsible Every $1 spent by NIH generates $2.46 For example, in 2023, $47B in NIH spending generated ~$93B Halting NIH spending will LOSE the US a lot of money (and talent)

An image of NIH campus. Text says : With annual budget of more than $47 billion, NIH is the largest single public funder of biomedical and behavioural research in the world. In fiscal year 2023, NIH funding generated an estimated $92.89 billion in economic activity

Every state and almost every congressional district received a share of NIH investment
Each year, NIH awards over 60,000 grants that directly support more than 300,000 researchers at more than 2,500 different institutions
In fiscal year 2023, every $1 of NIH funding generated approximately $2.46 of economic activity

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Fabian Theis @fabiantheis.bsky.social · 22/01/2025

Excited to see Moscot (moscot-tools.org) published in @Nature! We scaled Optimal Transport (OT) in single-cell genomics & added multimodality together with spatiotemporal trajectory inference, finding exciting new biology in the pancreas! 🚀 Read at www.nature.com/articles/s41...

nature.com

Mapping cells through time and space with moscot - Nature

Moscot is an optimal transport approach that overcomes current limitations of similar methods to enable multimodal, scalable and consistent single-cell analyses of datasets across spatial and temporal...

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BWJones @bwjones.bsky.social · 22/01/2025

Most folks do not understand how far in advance the planning and logistics of NIH grants take. We prepare for months or years for these submissions for one of 3 cycles per year. This study section cancellation delays grants by at least 6 months when study sections are cancelled.

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Science Magazine @science.org · 22/01/2025

“The impact of the collective executive orders and directives appears devastating.” scim.ag/40ureTO

scim.ag

Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring

Researchers facing

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@LaBonneLaB @labonnelab.bsky.social · 22/01/2025

Here it comes #science folks: Trump has instructed federal health agencies to pause all external communications, such as health advisories, weekly scientific reports, updates to websites and social media posts including officials at the National Institutes of Health

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Guardian US @us.theguardian.com · 22/01/2025

Winds picked up on Tuesday in southern California and at least a couple of new wildfires broke out as firefighters remained on alert two weeks after two major blazes are still burning in the LA area.

theguardian.com

California prepares for possible new fires as winds create conditions for ‘explosive growth’

Gusts could peak at 70mph (113km/h) along the coast and 100mph (160km/h) in the mountains and foothills

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Dan Diamond @ddiamond.bsky.social · 22/01/2025

New: Trump officials have paused all external communications at health agencies like CDC, FDA, NIH. No health alerts and the famed MMWRs; no updates to key websites or social media posts. And no indication how long the pause will last. With @rachelroubein.bsky.social + Lena Sun.

washingtonpost.com

Trump officials pause health agencies’ communications, citing review

The agencies are charged with making decisions that touch the lives of every American and are the source of crucial information to health-care providers.

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DrBreaky @drbreaky.bsky.social · 20/01/2025

Brains minimize energy consumption while maximizing computation. In humans, this trade-off is reconciled towards complex behaviors & hence relatively high energy use Review & synthesis with @sharnajamadar.bsky.social @annabhlr.bsky.social & Hamish Deery tinyurl.com/47c9n65w osf.io/preprints/os...

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Ryan Hoffman, PhD @ryanthescientist.bsky.social · 20/01/2025

So depending on what video you watch, they may have cut away when Elon did the Nazi salute... but it did happen Here is a link to NBCs video. It occurs 19sec into the video www.nbcnews.com/video/elon-m... I'm sorry to put this further out there more. But mainstream media is not talking about it

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