An automated nanoprobe system performs label-free mitochondrial sampling in living cells.

Fan et al. propose a non-genetically engineered, adoptive macrophage-based strategy via integrating anti-inflammatory (M2-like) macrophages with STING modulators to efficiently home to GBM and reshape the tumor immune microenvironment for improved therapeutic outcomes in mice models.

Nature Metabolism - Intercellular mitochondrial transfer has recently attracted substantial attention, both from a fundamental and therapeutic point of view. At the same time, the topic continues...

Bi, Mo, Liu et al. carry out high-throughput screening and analysis to profile genome-wide pro-tumour enhancers and uncover enhancer connectomes in glioma. In particular, they identify specific single...

Extracellular vesicles (EVs) are now recognized as powerful modulators of metabolism, and thus the new field of EV-mediated metabolic regulation is growing exponentially. Here, we discuss special expe...

Kim and Dixit review the hallmarks of immune aging with a focus on the interplay between metabolism and immune aging. They highlight metabolic pathways as potential therapeutic targets to improve immu...