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Reid Oshiro

@rtoshiro.bsky.social
240 followers 280 following 12 posts

Postdoc; Schrader lab, IU Biology | PostDoc; Seed lab, UC Berkeley | PhD, Microbiology; Kearns lab, IU Biology | Love microbiology and baking! HI ➡️ IN ➡️ CA ➡️ IN| he/him 🏳️‍🌈

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Reposted by Reid Oshiro
Jan-Ulrik Dahl (Dahl lab, ISU) @janulrikdahl.bsky.social · 25/09/2026
Join us and become my colleague! The School of Biological Sciences is opening the search for an Assistant Professor in the field of Host-Microbe Interactions with the targeted start date of Fall 2027. Please reach out to me with any questions you have: jobsearch.illinoisstate.edu/jobs/assista...
jobsearch.illinoisstate.edu
ASSISTANT PROFESSOR IN HOST-MICROBE INTERACTIONS (IMMUNOLOGY, MICROBIOLOGY) - Normal, Illinois, Illinois, United States
Title: ASSISTANT PROFESSOR IN HOST-MICROBE INTERACTIONS (IMMUNOLOGY, MICROBIOLOGY)Employee Classification: Asst ProfessorDivision Name: Academic AffairsCollege/Unit: College of Arts and SciencesDepart...
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Reposted by Reid Oshiro
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 19/09/2026
Genome-wide characterization of host factors involved in single-stranded RNA and DNA phage infection pathways www.biorxiv.org/content/10.64898/20…
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Tulilab.com @tulilab.bsky.social · 14/09/2026
IU is hiring a virologist. I am so excited. Come join a great group of scientists and people.
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artemisaev.bsky.social @artemisaev.bsky.social · 11/09/2026
Chromatin structure controls defense island expression! Why do some systems defend on plasmids but fail natively? H-NS is key. Removing it boosts defense and overcomes anti-defense proteins but raises toxicity. Common lab strains still hide novel immunity modules! www.biorxiv.org/content/10.6...
biorxiv.org
H-NS silences antiviral immunity through 3D chromatin compaction
Bacterial antiviral immunity systems can be toxic to their hosts and must be tightly regulated. Immunity genes are often encoded by AT-rich mobile genetic elements subjected to silencing by nucleoid b...
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Reposted by Reid Oshiro
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 12/08/2026
Minimal diadenylate cyclases have been co-opted to detect phage immune evasion www.biorxiv.org/content/10.64898/20…
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Reposted by Reid Oshiro
Malcolm White @mfwhite2.bsky.social · 11/08/2026
Tim Blower and I are guest editing a Biochemical Journal @biochemsoc.bsky.social themed collection on: The Prokaryotic Immune System It's now open for research submissions and we'd welcome submission of research and review articles. More info: portlandpress.com/biochemj/pag...
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Reposted by Reid Oshiro
artemisaev.bsky.social @artemisaev.bsky.social · 10/07/2026
Thrilled to share! We present the structure of a prototypical P2 OLD and reveal that its tRNAse activity is triggered by ssDNA hairpins in phage origins or unresolved termini in RecBCD-deficient cells. Great team effort with Wang, Bikard & Nudler labs. www.biorxiv.org/content/10.6...
biorxiv.org
OLD sentinel: an abortive tRNase surveys phage replication and DNA defects in RecBCD-compromised cells
OLD, an abortive immunity protein from prophage P2, consists of an ABC ATPase sensor and a TO-PRIM nuclease effector - a core architecture shared by a large protein family, including components of ant...
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Reposted by Reid Oshiro
Taga Lab @tagalab.bsky.social · 30/06/2026
Are you interested in #phages? The Taga Lab is looking to hire a postdoc with expertise in phage biology to work on a project about phage-mediated nutrient sharing. If you're interested, please reach out to Dr. Taga.
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Reposted by Reid Oshiro
Waggoner Lab @labwaggoner.bsky.social · 12/03/2026
Capturing dynamic phage–pathogen coevolution by clinical surveillance @nature.com @ucberkeleyofficial.bsky.social www.nature.com/articles/s41...
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Reposted by Reid Oshiro
Nature Microbiology @natmicrobiol.nature.com · 16/01/2026
Out Now! A phage protein screen identifies triggers of the bacterial innate immune system #MicroSky
go.nature.com
A phage protein screen identifies triggers of the bacterial innate immune system
Nature Microbiology, Published online: 16 January 2026; doi:10.1038/s41564-025-02239-6A library of 400 phage protein-coding genes is used to find a trove of antiphage systems, revealing systems that target tail fibre and major capsid proteins.
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Reposted by Reid Oshiro
Vivek Mutalik @vivekmutalik.bsky.social · 13/01/2026
Such a privilege to share the Phage Foundry (phagefoundry.org) team’s work at the inaugural GRC meeting on Microbiome Editing 🎉🎊.
Conference poster on microbiome editing
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Christina Stallings @stallingslab.bsky.social · 08/01/2026
We are hiring new faculty!! Come join our amazing community in the Department of Molecular Microbiology at Washington University School of Medicine! The deadline for applications is 2/21, but applications will be reviewed on a rolling basis. facultyopportunities.wustl.edu/Posting/Deta...
facultyopportunities.wustl.edu
Opportunity Details - Faculty Opportunities
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Reposted by Reid Oshiro
Christina Stallings @stallingslab.bsky.social · 06/01/2026
Registration is open for the 2026 Gordon Research Conference on Microbial Stress Response to be held on July 19-24 2026!! Submit your abstract by February 15th to be considered for a short talk. Apply now before it fills up!! Hope to see you there!! www.grc.org/microbial-st...
grc.org
2026 Microbial Stress Response Conference GRC
The 2026 Gordon Research Conference on Microbial Stress Response will be held in South Hadley, Massachusetts. Apply today to reserve your spot.
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Reposted by Reid Oshiro
Mark Mandel @markjmandel.bsky.social · 05/01/2026
Registration is open for September’s Vibrio2026 conference in Berlin! event.fourwaves.com/vibrio2026/p...
event.fourwaves.com
Vibrio2026: The International Meeting on the Biology of Vibrios
Join Vibrio2026: The International Meeting on the Biology of Vibrios, September 13-16, 2026. Learn more on Fourwaves.
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Reposted by Reid Oshiro
New England Biolabs @nebiolabs.bsky.social · 15/12/2025
Durham University (@durham.ac.uk) and NEB scientists described the first biochemical characterization of GmrSD Type IV restriction enzyme substrate specificity and inhibition by phage protein IP1*. royalsocietypublishing.org/doi/10.1…
royalsocietypublishing.org
Modified DNA substrate selectivity by GmrSD-family Type IV restriction enzyme BrxU
Abstract. Bacteriophages (phages), viral predators of bacteria, generate selection pressure that causes bacteria to evolve defence systems. Type I, II and
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Reposted by Reid Oshiro
anna brogan @apbrogan.bsky.social · 13/12/2025
Fer’s tour de force in B. anthracis is out! Fer got Tn-seq running, built an ordered knockout library, defined all essential sporulation genes, and found a peptidoglycan deacetylase inhibitor critical for engulfment. Including our first one-by-all Alphafold screen! journals.plos.org/plosbiology/...
journals.plos.org
Identification of sporulation genes in Bacillus anthracis highlights similarities and significant differences with Bacillus subtilis
How good is Bacillus subtilis as a model for the spore-forming pathogen Bacillus anthracis? Using high throughput genetics to identify B. anthracis sporulation genes and cytological analysis of the mu...
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Reposted by Reid Oshiro
Anthony Vecchiarelli @cellforganized.bsky.social · 12/12/2025
Just got word that we are a go for the Bacterial Cell Biology and Development GRS and GRC at Southern New Hampshire University! GRS will be on June 5-6, 2027 GRC will be from June 6-11, 2027 Block off your calendars Prokaryotic Cell Biologists! More details to come! Please repost!
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Joe Bondy-Denomy @jbdsf.bsky.social · 08/12/2025
Phages are full of genes of unknown function that are likely adaptive in specific conditions. New preprint: Phage TnSeq identifies essential genes rapidly and knocks all non-essentials. We would like to send a pool of phiKZ mutants to anyone wanting it! Reach out tinyurl.com/bdcfrejh
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Reposted by Reid Oshiro
Erez Yirmiya @erezyirmiya.bsky.social · 04/12/2025
I’m happy to share our new preprint! We uncovered the full diversity of bacterial TIR-based antiviral immune signaling, massively expanded the known diversity of Thoeris systems, and revealed conservation of TIR-derived immune signals across the tree of life. www.biorxiv.org/content/10.6...
biorxiv.org
Systematic discovery of TIR-based immune signaling systems in bacteria
Toll/interleukin-1 receptor (TIR) domains are important for immune signaling across humans, plants and bacteria. These domains were recently found to produce immune signaling molecules in plant immuni...
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Reposted by Reid Oshiro
Jack Bravo @jpkbravo.bsky.social · 02/12/2025
📢 We have multiple open PhD positions to study bacterial immune systems using cutting-edge cryo-EM, microbiology, and biochemistry in our group! Join us and uncover how bacterial defenses eliminate predators and engineer next-gen biotech tools. 🔥 Apply by Jan 8, 2026 Details: phd.pages.ista.ac.at
phd.pages.ista.ac.at
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Joe Bondy-Denomy @jbdsf.bsky.social · 01/12/2025
Check this out for the 2026 SISB (phage defense) meeting in NYC. Mark your calendar! (and note the Zoom option, if needed) sisb2026.rockefeller.edu
sisb2026.rockefeller.edu
SISB2026
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Reposted by Reid Oshiro
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 27/11/2025
Spatial constraint drives negative frequency dependent selection of phage weaponization www.biorxiv.org/content/10.1101/202…
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Dorentina Humolli @humollidorentina.bsky.social · 20/11/2025
First the link to the preprint: www.biorxiv.org/content/10.1...
biorxiv.org
Systematic mapping of bacteriophage gene essentiality with HIDEN‑SEQ
The constant arms race of bacteriophages and their bacterial hosts has inspired major breakthroughs in biotechnology and shaped phages as fierce predators with great clinical potential to fight multid...
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Reposted by Reid Oshiro
Michael Baym @baym.lol · 20/11/2025
Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/ www.science.org/doi/10.1126/...
science.org
Intracellular competition shapes plasmid population dynamics
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
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Reposted by Reid Oshiro
Alexander Harms @aharms485.bsky.social · 20/11/2025
🚨Preprint alert - this is a big one! We transfer the revolutionary power of TnSeq to bacteriophages. Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms. A thread 1/8
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Reid Oshiro @rtoshiro.bsky.social · 15/11/2025
I’m excited to share my recent postdoc work. Here, we interrogate how different phage infection outcomes (productive vs. restrictive) affect the expression of phage defense systems. We find that a restricted infection not only inhibits the phage but also induces increased immune protein abundance.
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Reposted by Reid Oshiro
Melanie Blokesch @mblokesch.bsky.social · 25/04/2025
Join the Blokesch lab (@EPFL) as a postdoc in Molecular Microbiology 🤩 Study Vibrio cholerae defense systems (phage/plasmid) in a dynamic, collaborative environment in Lausanne close to Lake Geneva in 🇨🇭! Please visit my lab's webpage for details about the position and how to formally apply.
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Adams Lab - Biology of Spirochetes @adamslab.bsky.social · 18/12/2024
Adams Group webpage is live! #NIAIDNews #IRPatNIH #ResearchingSpirochetes 🔬🧫🧬 (Consider joining our team!!) www.niaid.nih.gov/research/ada...
niaid.nih.gov
Adams Research Group
The Adams Research Group uses molecular and cellular techniques to manipulate spirochetes, sequence bacterial transcriptomes, characterize cellular processes, map regulatory networks, and study spiroc...
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Reposted by Reid Oshiro
Dr. Aisha Burton @aishaburton.bsky.social · 12/11/2024
Since we have had a big boom to bsky let me reintroduce myself. I am Aisha Burton and a new PI at Cornell Micro. Currently on maternity leave but my two research techs are keeping the research going 🙏🏾. My lab is interested in studying small proteins and how they impact stress responses in bacteria
Burton lab in big black letters. DNA helix connects B of Burton and L of Lab. Between the two words there is smaller text that reads Large Roles Small proteins.
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Reid Oshiro @rtoshiro.bsky.social · 10/05/2024
Really excited to share my first preprint as a postdoc! Here, we determined that the BREX-inhibitor, OrbA, encoded by the lytic phage ICP1 inhibits BREX through the ATPase BrxC in V. cholerae. www.biorxiv.org/content/10.1...
biorxiv.org
The vibriophage-encoded inhibitor OrbA abrogates BREX-mediated defense through the ATPase BrxC
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Reid Oshiro @rtoshiro.bsky.social · 09/11/2023
Attention phage/microbiology 🧫🦠enthusiasts- the Seed lab kimseedlab.com @UCBerkeley is hiring a staff research associate, an ideal opportunity for folks looking to gain research experience before grad school/professional school careerspub.universityofcalifornia.edu/psp/ucb/EMPLOY… please share!
kimseedlab.com
Seed Lab
Kim Seed is an Assistant Professor at the University of California, Berkeley and her lab studies the interactions between bacteria and their viral predators (bacteriophages), and how these interacti...
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Reid Oshiro @rtoshiro.bsky.social · 21/09/2023
Yay @aishaburton.bsky.social glad to see this out!
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