It's been a long time since I sat down and enjoyed reading a paper cover-to-cover as much as this. Some cracking work and experiments.
www.science.org/doi/10.1126/...
science.org
Mechanical loading induces the longitudinal growth of muscle fibers via a rapamycin-insensitive mechanism
mTORC1 does not always hold the key to unlocking the mechanical load-induced growth of skeletal muscle.