iiinova — where your digital self keeps evolving

Reposted by German Demidov

Oxford Nanopore @nanoporetech.com · 26/06/2025

ELRIN completes two T2T human genomes — using only #Nanopore data. As part of their mission to advance clinical diagnostics, ELRIN has released two complete, haplotype-phased genomes—enabling deeper insights into genetic variation that could inform future clinical research elrin-network.eu/t2t.html

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German Demidov @reptiloid.bsky.social · 15/06/2025

I agree with the message, from Germany, but for different reasons...

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German Demidov @reptiloid.bsky.social · 26/05/2025

Could not come to #eshg this year, but hey I also had a productive weekend I started to run maybe 2 years ago, so obviously it is just a very amateur thing, but still I am glad that I started even at my age www.medizin.uni-tuebingen.de/de/das-klini...

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German Demidov @reptiloid.bsky.social · 20/05/2025

Let's go for a scientific conference in the US, they say. It will be fun, they say.

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German Demidov @reptiloid.bsky.social · 09/05/2025

I am not a deep learning specialist, but I laughed

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German Demidov @reptiloid.bsky.social · 29/04/2025

"Want something to drink?" she asked, opening the fridge. "There's water, milk, spiders, Dr. Pepper..." "Spiders?" "Alright, spiders." "No, I mean..." But she was already pouring the spiders.

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German Demidov @reptiloid.bsky.social · 29/04/2025

I hope they are not mRNA based // dark times dark jokes

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German Demidov @reptiloid.bsky.social · 27/04/2025

Any academic paper authors be like

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German Demidov @reptiloid.bsky.social · 16/04/2025

Twenty more people now know that I am stupid and cannot check table labels before the submission

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Reposted by German Demidov

Emma Chory, Ph.D. @chorye.bsky.social · 14/04/2025

When investors learn that the trait for green eyes is also ~20 SNPs

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German Demidov @reptiloid.bsky.social · 13/04/2025

The feeling I have living 13km from Universitätsstadt Tübingen in a normal non academic town when I see someone reading a sci paper in a Biergarten

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Reposted by German Demidov

Maxim Greenberg @maxvcg.bsky.social · 11/04/2025

The Americans are doing to Kseniia what the Russians did to Brittney Griner for having 0.7 grams of cannabis oil. Except no one is coming to negotiate her freedom and Harvard is sitting on their hands. I am so ashamed. Please share this story. www.nytimes.com/2025/04/11/s...

nytimes.com

She Worked in a Harvard Lab to Reverse Aging, Until ICE Jailed Her (Gift Article)

President Trump’s immigration crackdown ensnared Kseniia Petrova, a scientist who fled Russia after protesting its invasion of Ukraine. She fears arrest if she is deported there.

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Reposted by German Demidov

Eric Topol @erictopol.bsky.social · 24/03/2025

These are the specific foods that were linked with healthy aging and other outcomes. Green-favorable; Red-unfavorable

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Reposted by German Demidov

Eric Topol @erictopol.bsky.social · 22/03/2025

I've reviewed 10 consumer-facing companies that are in the business of promoting longevity and healthspan erictopol.substack.com/p/the-busine... Open-access, in the new edition of Ground Truths

Table of 10 companies selling longevity and extended healthspan

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Reposted by German Demidov

Albert Vilella, PhD. @albertvilella.bsky.social · 22/03/2025

We are going from expensive eggs to no eggs at all.

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German Demidov @reptiloid.bsky.social · 10/03/2025

"The Fake News losers at CNN immediately tried to fact check it, but President Trump was right (as usual)." As a Russian I would like to protest, only Lavrov is allowed to use such a language, Trump is just copying www.whitehouse.gov/articles/202...

whitehouse.gov

Yes, Biden Spent Millions on Transgender Animal Experiments

Last night, President Donald J. Trump highlighted many of the egregious examples of waste, fraud, and abuse funded by American taxpayers, including $8

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Reposted by German Demidov

Eric Topol @erictopol.bsky.social · 09/03/2025

Research support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH. Such work is exemplified by Prof Anna Greka @broadinstitute.org in a new Ground Truths podcast. Open-access, w/ transcript, video, no ads erictopol.substack.com/p/anna-greka...

erictopol.substack.com

Anna Greka: Molecular Sleuthing for Rare Diseases

Listen now | Finding the Mechanisms and the Basis for Potential Cures

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Reposted by German Demidov

Carl T. Bergstrom @carlbergstrom.com · 06/03/2025

Let's talk about this Nature piece in more detail. I've rarely read something so anti-scientific anywhere short of the National Review. www.nature.com/articles/d41...

nature.com

Three AI-powered steps to faster, smarter peer review

Tired of spending countless hours on peer reviews? An AI-assisted workflow could help.

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German Demidov @reptiloid.bsky.social · 01/03/2025

In moments like this I regret I left twitter and promised myself not to post anything political on Bluesky

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German Demidov @reptiloid.bsky.social · 23/02/2025

I thought the ideocracy will come to the world just as the increased proportion of idiots, but it seems that it will come as chat-gepatit virus Very contagious, it replaces parts of human brains responsible for critical thinking, and in my experience, irreversible

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German Demidov @reptiloid.bsky.social · 22/02/2025

My carefully selected feed of scientists now 90% consists of posts about politics I don't judge

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German Demidov @reptiloid.bsky.social · 19/02/2025

judging the speed of idiocracy spreading across the world, I just hope they won’t burn us [scientists] at the stake or at absolute minimum 1) they won't do it too soon 2) they will do it fast

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German Demidov @reptiloid.bsky.social · 12/02/2025

we switched to Teams, but can't install Teams due to the security problems on our work computers you know which browser can't handle Microsoft Teams browser version? Microsoft Edge

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Reposted by German Demidov

ERN-RND @ern-rnd.bsky.social · 10/02/2025

"Having a diagnosis for patients, who had no diagnosis, is the most important thing" - over 300 experts from the #EU and Canada re-analysed genome data from 6447 patients and were able to diagnose 506 patients and their families. More about this reasearch project: www.radboudumc.nl/en/news-item...

youtube.com

Solve-RD: The Worth or Reanalysis (Holm Graessner)

YouTube video by ERN-RND

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German Demidov @reptiloid.bsky.social · 08/02/2025

I have a rare genetic disorder the problem is that I am always right about everything

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German Demidov @reptiloid.bsky.social · 08/02/2025

you say "CNVs were called using a previously published pipeline", but you do it without the proper reference to the tool

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German Demidov @reptiloid.bsky.social · 07/02/2025

do you remember blockchain? it's him now feel old yet?

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German Demidov @reptiloid.bsky.social · 06/02/2025

We as scientists are concentrated on solving the unsolved cases with tricky causal variants But the biggest impact would be produced just by the increased number of routine tests

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German Demidov @reptiloid.bsky.social · 05/02/2025

Ah, an error in one (1) index in a 1000s lines script that required three full days for debug Long time no see I was not missing you

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Reposted by German Demidov

Eric Topol @erictopol.bsky.social · 04/02/2025

New: The largest medical A.I. randomized controlled trial yet performed, enrolling >100,000 women undergoing mammography screening The use of AI led to 29% higher detection of cancer, no increase of false positives, and reduced workload compared with radiologists w/o AI thelancet.com/journals/lan...

thelancet.com

Screening performance and characteristics of breast cancer detected in the Mammography Screening with Artificial Intelligence trial (MASAI): a randomised, controlled, parallel-group, non-inferiority, ...

The findings suggest that AI contributes to the early detection of clinically relevant breast cancer and reduces screen-reading workload without increasing false positives.

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German Demidov @reptiloid.bsky.social · 04/02/2025

I was an organiser of several educational events inside and outside of Germany and I realized the biggest issue for me in Germany is that there are almost no photos or videos after any of these People simply don't take photos in Germany Because of privacy, yes, but in the end it is just...not nice..

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German Demidov @reptiloid.bsky.social · 31/01/2025

My paper was cited 5 times last week according to Research Gate. This is good. All of the citations come from the same authors (but different book chapters) in a garbage pseudo-scientific book where even the topic does not match. How can I remove these citations?

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Reposted by German Demidov

Prof Sheena Cruickshank @sheencr.bsky.social · 31/01/2025

Absolutely fantastic news as sickle cell gene therapy is to be rolled out for sickle cell academia with a one off treatment curing 97% of patients 🧪

theguardian.com

‘Groundbreaking’ potential cure for sickle cell in England approved for NHS use

Clinical trials find one-time gene therapy exa-cel offers ‘functional cure’ in 96.6% of patients

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German Demidov @reptiloid.bsky.social · 30/01/2025

I mean, I didn't really want to, but I need to go to the ERDERA satellite meeting anyway...

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German Demidov @reptiloid.bsky.social · 30/01/2025

...when you make a lot of comments in a draft of a paper you co-author and find all of them rejected

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