The Institute of Human Genetics invites applications for a Principal Investigator position in its main research areas. Read more...

Three-dimensional (3D) genome organization plays a central role in gene regulation, chromatin folding, and genome stability. Although chromosome-conformation capture (3C)-derived methods have revoluti...

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Nature Communications - Determining how replication forks move across the human genome is critical for the effective use of agents that target replication stress. Here, the authors present...

Posted 8:04:09 PM. About UsInstitut Curie Research CenterInstitut Curie is a major player in the research and fight…See this and similar jobs on LinkedIn.

Delamarre et al. develop a technology named PCP that can simultaneously map complex spatial relationships between millions of molecules. Using PCP, they investigate chromatin structure and describe si...

Background The identification of sites of DNA replication initiation in mammalian cells has been challenging. Here, we present unbiased detection of replication initiation events in human cells using ...

Investigating the relationships between R-loops and genetic instability led to the discovery that some DNA:RNA hybrids actually arise as a consequence of DNA lesions.

Investigating the relationships between R-loops and genetic instability led to the discovery that some DNA:RNA hybrids actually arise as a consequence of DNA lesions.

Nature Reviews Molecular Cell Biology - Changes in nuclear and genome organization promote the repair of DNA double-strand breaks and genome stability. Processes that are involved include the...

Nature Communications - DNA:RNA hybrids are linked to genetic instability in several pathological situations. Here, the authors report that various types of DNA lesions can trigger hybrid formation...