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PRIMED Consortium

@prsmethods.bsky.social
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The NIH-funded Polygenic Risk Methods Development (PRIMED) Consortium. primedconsortium.org

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PRIMED Consortium @prsmethods.bsky.social · 25/08/2026
Check out Coordinating Center member Stephanie Gogarten presenting at @elsihub.bsky.social ELSI Congress on "Sensitive sociobehavioral traits in the construction of ensemble Polygenic Risk Score models" vimeo.com/1206496440?f...
vimeo.com
B4. Polygenic Scores, Responsibility, and Social Risk
This is "B4. Polygenic Scores, Responsibility, and Social Risk" by ELSIhub by CERA on Vimeo, the home for high quality videos and the people who love them.
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PRIMED Consortium @prsmethods.bsky.social · 25/08/2026
🧬 👀 In addition to innovating methods for genetic risk prediction across different contexts, the @prsmethods.bsky.social consortium is proactively considering ethical and social implications of its work 🎬 See our video collection: primedconsortium.org/education#et...
primedconsortium.org
Education | PRIMED Consortium
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PRIMED Consortium @prsmethods.bsky.social · 07/08/2026
🎬 New Friday video drop! Watch @prsmethods.bsky.social investigator Micah Hysong present on "Practical considerations for social determinant-based disease prediction," using the NIH All of Us research program data primedconsortium.org/education#en...
primedconsortium.org
Education | PRIMED Consortium
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PRIMED Consortium @prsmethods.bsky.social · 30/07/2026
🔖 Read about our Research Highlights primedconsortium.org/research/hig... 📹 Watch PRIMED investigators in our Video Collection primedconsortium.org/education#vi... Follow us at @prsmethods.bsky.social
primedconsortium.org
Research Highlights | PRIMED Consortium
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PRIMED Consortium @prsmethods.bsky.social · 30/07/2026
The NIH-funded PRIMED (Polygenic Risk Methods Development) Consortium was launched in 2021 and is working to address gaps noted in this recent @nytimes.com article www.nytimes.com/2026/07/20/s...
nytimes.com
This Lifesaving Genetics Tool Works Best if You’re White
Genetic prediction models are poised to revolutionize medicine. But because they have been trained on European DNA, they threaten to widen health care disparities.
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PRIMED Consortium @prsmethods.bsky.social · 17/07/2026
Watch @prsmethods.bsky.social investigators Dave Conti and Sara Cromer present on "Incorporating Polygenic Risk Scores and Social Determinants of Health Across Populations" from the May @ajhgnews.bsky.social journal club, now added to our PRIMED video collection: primedconsortium.org/education#en...
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PRIMED Consortium @prsmethods.bsky.social · 17/06/2026
🎉 Congratulations to @prsmethods.bsky.social investigators on this work on developing genetic risk scores for type 2 diabetes in diverse ancestry populations
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PRIMED Consortium @prsmethods.bsky.social · 11/06/2026
🎉 Congratulations to @prsmethods.bsky.social investigators on this manuscript advancing contextualization of genetic risk 🧬
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Reposted by PRIMED Consortium
Sarah Nelson @blueyedgenes.bsky.social · 27/05/2026
👋 Come work on our new ELSI (Ethical, Legal, and Social Implications) R01 grant focused on cloud-based platforms and their promise to ‘democratize’ the genomic data sciences ☁️ 🧬 wd5.myworkdaysite.com/recruiting/u...
wd5.myworkdaysite.com
Research Coordinator 3 (E S UAW Research)
Job Description OVERVIEW: The University of Washington Department of Bioethics and Humanities (B&H) has an outstanding opportunity for a full-time Research Coordinator 3 to support a recently awar...
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PRIMED Consortium @prsmethods.bsky.social · 30/04/2026
🗓️ Join @prsmethods.bsky.social investigators on May 13 to discuss integrating Social Determinants of Health (SDoH) and polygenic risk scores 👀 Event information: bit.ly/4chGKtr 🔖 Publication: pubmed.ncbi.nlm.nih.gov/41785862/
bit.ly
American Society of Human Genetics: Incorporating Polygenic Risk Scores and Social Determinants of Health Across Populations
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PRIMED Consortium @prsmethods.bsky.social · 08/04/2026
Funding for BGE sequencing and analyses are provided through the NIH-funded @prsmethods.bsky.social consortium For more information and how to apply for access, visit primedconsortium.org/research/our... 3/
primedconsortium.org
OurHealth study | PRIMED Consortium
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PRIMED Consortium @prsmethods.bsky.social · 08/04/2026
The release adds 391 participants with Blended Genome-Exome sequencing, imputed genotypes, and cardiometabolic phenotypes, for a total of 1012 participants 2/
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PRIMED Consortium @prsmethods.bsky.social · 08/04/2026
👀🧬🫀 ICYMI - updated data release from the OurHealth study of Cardiovascular Disease in South Asians now available on @anvilproject.org! anvilproject.org/releases/202... 1/
anvilproject.org
March 2026 Release - AnVIL Portal
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Reposted by PRIMED Consortium
American Society of Human Genetics (ASHG) @geneticssociety.bsky.social · 13/03/2026
The authors of the @ajhgnews.bsky.social latest article explore the opportunities and challenges of harmonizing data across cohorts & biobanks & outline key ethical considerations for conducting or reporting this work: bit.ly/4dbA3JZ #ASHG @prsmethods.bsky.social
bit.ly
Incorporating polygenic risk scores and social determinants of health across populations: Considerations and best practices in research
Despite increasing focus on the intersection of genetic and social risk factors on health, heterogeneity in how these factors are measured, distributed, and analyzed across populations and datasets co...
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Reposted by PRIMED Consortium
Gen Wojcik @genandgenes.bsky.social · 04/03/2026
Are you interested in understanding how social and structural determinants of health influence estimates of genetic risk? Looking for figures for teaching these concepts? Check out our work on considerations for modeling them together, led by Sara Cromer and Dave Conti with @prsmethods.bsky.social
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PRIMED Consortium @prsmethods.bsky.social · 27/02/2026
The @prsmethods.bsky.social consortium - in 5 years, going from "Can we predict disease genetically" to "Can we predict disease in a way that's accurate, equitable, and clinically useful across diverse populations?" Find out more at primedconsortium.org/research/hig...
Circle of PRIMED themes across discovery and methods, diversity and equity, gene-environment, clinical context, and clinical impact
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PRIMED Consortium @prsmethods.bsky.social · 12/01/2026
The call for #DNADay26 essays is out! Open to students in grades 9-12 📝 🧬 Pro tip for genetics professionals: the contest is also often looking for judges...
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PRIMED Consortium @prsmethods.bsky.social · 09/01/2026
Follow us for more highlights throughout the year and see our running lists of publications and research highlights primedconsortium.org/publications... primedconsortium.org/research/hig... end/
primedconsortium.org
View Publications | PRIMED Consortium
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PRIMED Consortium @prsmethods.bsky.social · 09/01/2026
November also saw the first data release of genetic and phenotypic data from the OurHealth study, with blended genome-exome sequencing funded by PRIMED, primedconsortium.org/research/our... 8/
primedconsortium.org
OurHealth study | PRIMED Consortium
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PRIMED Consortium @prsmethods.bsky.social · 09/01/2026
Recommendations for the responsible use of population descriptors in polygenic risk development were published in November pubmed.ncbi.nlm.nih.gov/41286102 7/
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PRIMED Consortium @prsmethods.bsky.social · 09/01/2026
At #ASHG25, a range of PRIMED work was presented in talks and posters docs.google.com/spreadsheets... 6/
docs.google.com
ASHG 2025 PRIMED Abstracts
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PRIMED Consortium @prsmethods.bsky.social · 09/01/2026
PRIMED members investigated incorporating social determinants of health into disease prediction in the NIH All of Us Research Program doi.org/10.1101/2025... 5/
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PRIMED Consortium @prsmethods.bsky.social · 09/01/2026
The Data Sharing Working Group published a review of PRIMED consortium data sharing procedures and policy recommendations for future initiatives pubmed.ncbi.nlm.nih.gov/40628271 4/
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PRIMED Consortium @prsmethods.bsky.social · 09/01/2026
The Population Descriptors, Social and Ethical Implications Working Group published a new data model that allows flexible and responsible use of population descriptors, and aligns with @nationalacademies.org recommendations pubmed.ncbi.nlm.nih.gov/40513563 3/
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PRIMED Consortium @prsmethods.bsky.social · 09/01/2026
We joined Bluesky! Here’s our PRIMED investigator starter pack - bsky.app/starter-pack... 2/
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PRIMED Consortium @prsmethods.bsky.social · 09/01/2026
PRIMED Year in Review: Join us as we look back on some of what @prsmethods.bsky.social consortium members accomplished in 2025 to help improve genetic risk prediction in global populations 1/
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PRIMED Consortium @prsmethods.bsky.social · 03/12/2025
Funding for BGE sequencing and analyses are provided through the NIH-funded PRIMED Consortium @prsmethods.bsky.social For more information and how to apply for access, visit primedconsortium.org/research/our... /end
primedconsortium.org
OurHealth study | PRIMED Consortium
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PRIMED Consortium @prsmethods.bsky.social · 03/12/2025
The release includes self-reported basic demographics, anthropometric traits, cardiometabolic outcomes, and Blended Genome-Exome sequencing data on 621 study participants 2/
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PRIMED Consortium @prsmethods.bsky.social · 03/12/2025
🧬🫀🌏 NEW data release from the OurHealth study of Cardiovascular Disease in South Asians now available on @anvilproject.org! anvilproject.org/news/2025/11... 1/
anvilproject.org
Release of The OurHealth Study on the AnVIL Platform - AnVIL Portal
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PRIMED Consortium @prsmethods.bsky.social · 02/12/2025
📢 New from the @prsmethods.bsky.social consortium, "Recommendations for responsible use of population descriptors in polygenic risk score development"! H/t to leads @johannalsmith.bsky.social and Quan Sun www.nature.com/articles/s41... in @natgenet.nature.com
nature.com
Recommendations for responsible use of population descriptors in polygenic risk score development - Nature Genetics
In this Perspective, authors from the Polygenic Risk Methods Development (PRIMED) Consortium highlight the ethical and analytical impact of population descriptors in polygenic risk score development a...
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PRIMED Consortium @prsmethods.bsky.social · 07/11/2025
🎉 Congrats to Julie-Alexia Dias and thanks for the shout out to @prsmethods.bsky.social ! "Some of the most formative parts of my own training have come from working across groups and institutions...through my involvement in PRIMED (Polygenic Risk Methods Development)..."
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PRIMED Consortium @prsmethods.bsky.social · 29/10/2025
👀 🔖 ICYMI @prsmethods.bsky.social investigators report on incorporating social determinants of health into disease prediction in the NIH All of Us research program - www.medrxiv.org/content/10.1...
medrxiv.org
Quantifying Social Determinants of Health for Disease Prediction: A Multi-Level Approach Using Healthy People 2030 and All of Us Data
Despite the growing recognition that social determinants of health (SDoH) play a prominent role in shaping health outcomes, inconsistent measures across health systems and research studies - and the a...
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PRIMED Consortium @prsmethods.bsky.social · 14/10/2025
Attending #ASHG25? Learn how @prsmethods.bsky.social investigators are improving polygenic risk prediction in diverse populations by visiting these talks and posters docs.google.com/spreadsheets...
docs.google.com
ASHG 2025 PRIMED Abstracts
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PRIMED Consortium @prsmethods.bsky.social · 10/10/2025
👀🔖 Check out this new review by @prsmethods.bsky.social member Iftikhar Kullo, which explores the current state of the field, highlights key challenges, and outlines future directions for the use of PRSs to improve risk prediction and to advance personalized prevention in clinical care
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Reposted by PRIMED Consortium
Arun Durvasula @arundurvasula.bsky.social · 03/09/2025
Excited to share our latest manuscript, "Exposure accumulation drives age-dependent disease architectures and polygenic risk scores," led by Xilin Jiang: www.medrxiv.org/content/10.1... I am attempting an explainer thread for the first time here: (I am usually too exhausted to post one)
medrxiv.org
Exposure accumulation drives age-dependent disease architectures and polygenic risk scores
Our understanding of the dependence of the genetic and environmental architecture of common diseases on age is incomplete. Here, we use longitudinal data to quantify age-dependent genetic and environm...
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PRIMED Consortium @prsmethods.bsky.social · 25/08/2025
‪The PRIMED Consortium has a new handle: @prsmethods.bsky.social! Please tag us there when referencing our work or to share with us the latest in PRS methods development. We’re excited to keep connecting with you!
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PRIMED Consortium @prsmethods.bsky.social · 15/08/2025
👀 🔖 Congrats to @aliciahuerta.bsky.social @josepmercader.bsky.social and @prsdiversity.bsky.social co-authors and collaborators on this pre-print demonstrating that multi-ancestry PRSs improve T2D prediction across all ancestries www.medrxiv.org/content/10.1...
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PRIMED Consortium @prsmethods.bsky.social · 14/08/2025
📣 Reminder that @anvilproject.org is calling all genomic researchers, data scientists, and cloud computing enthusiasts to register for the AnVIL Community Conference In-person registration closes Aug 19: https:/bit.ly/anvil2025
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PRIMED Consortium @prsmethods.bsky.social · 02/08/2025
Thanks to @elsihub.bsky.social for featuring "A data model for population descriptors in genomic research" from the NIH-funded @prsdiversity.bsky.social consortium in their "New Publications" section! www.cell.com/ajhg/abstrac... elsihub.org/news-and-eve...
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Reposted by PRIMED Consortium
NHGRI AnVIL @anvilproject.org · 10/07/2025
🚨 Registration is OPEN for #AnVILCommunity2025 Conference! Join us in Nashville, Sept 3-5 for talks, posters, & CoFest! - Regular rate ($75): bit.ly/acc2025-register - Student rate ($25): bit.ly/acc2025-register-student - Virtual (free!): bit.ly/acc2025-register-virtual Don’t miss it!
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PRIMED Consortium @prsmethods.bsky.social · 11/07/2025
Co-authors include @johannalsmith.bsky.social, @quennawong.bsky.social, Whitney Hornsby, @mconomos.bsky.social, @blueyedgenes.bsky.social, and the Data Sharing Working Group! @prsdiversity.bsky.social is an NHGRI and NCI funded Consortium
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PRIMED Consortium @prsmethods.bsky.social · 11/07/2025
🎉 Out now in @ajhgnews.bsky.social: the @prsdiversity.bsky.social perspective on data sharing to improve genetic risk prediction in global populations 🧬🌎 🌍🌏 See also our thread on the pre-print - bsky.app/profile/prsd...
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PRIMED Consortium @prsmethods.bsky.social · 02/07/2025
ICYMI - see this recent work from the NIH-funded PRIMED Consortium @prsdiversity.bsky.social introducing a data model for population descriptors in genomic research 🎉 published in @ajhgnews.bsky.social www.cell.com/ajhg/abstrac...
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PRIMED Consortium @prsmethods.bsky.social · 25/04/2025
Happy #DNADay25 from the PRIMED Consortium @prsdiversity.bsky.social! Genetic information can help improve risk prediction for a broad range of health outcomes. Learn more: 🧬 Publications: primedconsortium.org/publications... 🧬 Research Highlights: primedconsortium.org/research/hig...
primedconsortium.org
View Publications | PRIMED Consortium
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Reposted by PRIMED Consortium
Gen Wojcik @genandgenes.bsky.social · 24/04/2025
I wrote a thing. I am eternally grateful for my editor, who took the original draft and helped me narrow down my key points into a more effective piece with a broader reach. Also, thanks to the editorial & legal teams, who maintained the message while protecting us in this fraught moment.
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PRIMED Consortium @prsmethods.bsky.social · 09/04/2025
Find this and other @prsdiversity.bsky.social publications and preprints on our website, primedconsortium.org/publications...
primedconsortium.org
View Publications | PRIMED Consortium
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PRIMED Consortium @prsmethods.bsky.social · 09/04/2025
They also discuss current challenges in fully using local ancestry in genetic epidemiological studies and suggest future directions towards its full usage. 3/
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PRIMED Consortium @prsmethods.bsky.social · 09/04/2025
Quan Sun and colleagues at the EPIC-PRS PRIMED Site review methods to infer and incorporate local ancestry in various analyses including admixture mapping, association testing, and polygenic prediction. 2/
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PRIMED Consortium @prsmethods.bsky.social · 09/04/2025
👀 🔖 🧬 New @prsdiversity.bsky.social publication out in @ajhgnews.bsky.social, "Opportunities and challenges of local ancestry in genetic association analyses" 1/ www.sciencedirect.com/science/arti...
sciencedirect.com
Opportunities and challenges of local ancestry in genetic association analyses
Recently, admixed populations make up an increasing percentage of the US and global populations, and the admixture is not uniform over space or time o…
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Reposted by PRIMED Consortium
Elizabeth Atkinson @egatkinson.bsky.social · 03/04/2025
I'm delighted to be part of this symposium, put on by University of Pennsylvania Perelman School of Medicine, and led by @bpasaniuc.bsky.social and @sarahtishkoff.bsky.social. See you in a few weeks! upenn.co1.qualtrics.com/jfe/form/SV_...
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