The autumn bugs are doing the rounds right now.

How we write scientific papers does not reflect how we do science, masking the human in the process by design. This Perspective invites us to consider the structure of the scientific paper, and the ne...

How we write scientific papers does not reflect how we do science, masking the human in the process by design. This Perspective invites us to consider the structure of the scientific paper, and the ne...

Funding is often secured through Wellcome Trust or MRC DTP Fellowships. Further information about this and specific projects studying under the supervision of Departmental supervisors who have obtaine...

Respiratory syncytial virus (RSV) remains a health threat to young children worldwide. The host immune response plays a key role in disease following infection. Infection models advance our understand...

Live Forever?: A Curious Scientist’s Guide to Wellness, Ageing and Death : Tregoning, Prof. John S.: Amazon.ie: Books

The COVID-19 pandemic highlighted the need for rapidly deployable, flexible vaccine platforms; particularly RNA which is now being explored for several other pathogens. DNA vaccines have potential advantages over RNA, including cost of manufacture, ease of storage and potentially lower reactogenicit …

Challenges with vaccine reactogenicity, stability, and access have highlighted the need to develop alternative strategies for formulation and delivery. We explored the incorporation of cucurbit[n]urils (CBs), as supramolecular "hosts," into nucleic acid-polymer polyplexes. CBs are small, non-toxic, …

Vaccines are central to the strategy to control antimicrobial resistant (AMR) bacterial infections; one multidrug resistant pathogen of particular concern is Acinetobacter baumannii. In this study we identified two novel A. baumannii antigens using mass spectrometry and phage expression: Oxa23 and P …

Two-photon polymerization (2PP) 3D printing enables top-down biomaterial synthesis with nanoscale spatial resolution for de novo design of monodisperse injectable drug delivery systems. Spatiotemporal Controlled Release Inks of Biocompatible polyEsters (SCRIBE) is a novel poly(lactic-co-glycolic aci …

Self-amplifying RNA (saRNA) is an extremely promising platform because it can produce more protein for less RNA. We used a sort and sequence approach to identify host cell factors associated with transgene expression from saRNA; the hypothesis was that cells with different expression levels would ha …

The development of a universal influenza vaccine likely requires an understanding of previous exposure to influenza virus (through vaccination or infection) and how that shapes the antibody repertoire to vaccination, sometimes called original antigenic sin or antigenic imprinting. While animal model …

This work was supported by the NIHR Health Protection Research Unit in Respiratory Infections, United Kingdom, NIHR Imperial College London, United Kingdom (Grant number: NIHR200927; AL) in partnership with the UK Health Security Agency and the NIHR Medical Research Council (MRC), United Kingdom (Gr …

The changes announced by a major UK science funder are putting scientists — and the future of research — in a difficult position.

Events at Waterstones get you closer to the books and authors you admire most. Find information and tickets about Deborah Cohen & Prof. John S.Tregoning in conversation today.

This 1970s notion is a bit of a myth – but it’s still a good idea to wear a hat if it’s cold out

Live Forever?: A Curious Scientist’s Guide to Wellness, Ageing and Death : Tregoning, Prof. John S.: Amazon.co.uk: Books

Experts weigh in on whether cold water swimming, drinking kombucha and taking vitamins can boost your immune system.

Experts weigh in on whether cold water swimming, drinking kombucha and taking vitamins can boost your immune system.

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Nature asked contributors, editors and working researchers to share their best advice for scientists.

At a recent ceremony for world leaders in Beijing, a hot mic picked up a surprising exchange between Vladimir Putin and Xi Jinping about the possibility of living to 150. Putin suggested the secret mi...

Given the explosion of RNA vaccines in the last 5 years, this review explores gaps in knowledge and what is needed to fill these. Tregoning and colleagues focus on the immune response to RNA vaccines,...

Nucleic acid vaccines require antigen expression and inflammation to induce the adaptive immune response. Sallah and colleagues explored the use of cucurbiturils as supramolecular “hosts” to crosslink...

Two-photon polymerization (2PP) 3D printing enables top-down biomaterial synthesis with nanoscale spatial resolution for de novo design of monodisperse injectable drug delivery systems. Spatiotemporal...

npj Vaccines - Intranasal delivery of mRNA expressing newly identified Acinetobacter baumannii antigens protects against bacterial lung disease

Discover Research Assistant in Vaccine Immunology jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

Profs Daniel M Davis & John Tregoning: Boosting Immune Health – To Live, Well, Forever?

Profs Daniel M Davis & John Tregoning: Boosting Immune Health – To Live, Well, Forever?

Live Forever?: A Curious Scientist's Guide to Wellness, Ageing and Death eBook : Tregoning, John S.: Amazon.co.uk: Books