Florian Privé @privefl.bsky.social · 20/08/2025LEAVING ACADEMIA Although I did not manage to secure the funding needed to establish my own research group, I am grateful for what I’ve learned in academia. *I am now beginning a new chapter*, joining a very early startup in France working on detecting cancer from DNA circulating in the blood. 2282
Florian Privé @privefl.bsky.social · 20/07/2025But you shouldn’t use only 2 PCs to compute the distance 😉 020
Florian Privé @privefl.bsky.social · 04/07/2025I probably won't have time to make a video out of this. But the materials are available online, and should be pretty self-explanatory. Hope this is useful to some people. privefl.github.io/statgen-cour...privefl.github.ioStatistical Human Genetics course using RStatistical Human Genetics course using R 13915
Florian Privé @privefl.bsky.social · 20/06/2025Next week, I'm teaching a **Statistical Human Genetics course using R**; would be of interest if I try to record it to make it available as a Youtube video? 5312
Reposted by Florian PrivéAndrea Ganna @andganna.bsky.social · 01/06/2025We have 2-3 group leader positions opening @fimm-uh.bsky.social !! We are looking for outstanding candidates in human genetics and precision medicine. This time we have a focus on population health data science. E.g. AI for EHR/health data Generous starting package 💰 shorturl.at/FAk6njobs.helsinki.fiFIMM-EMBL Group Leaders in Molecular MedicineFIMM-EMBL Group Leaders in Molecular Medicine 03845
Reposted by Florian PrivéAndrea Ganna @andganna.bsky.social · 21/05/2025We are looking for a post-doc/research fellow working on non-bullshit, reality-centered AI. Meaning: unique nationwide EHR and -omics with the possibility to recontact people and prospectively test multimodal AI approaches. jobs.helsinki.fi/job/Helsinki... @FIMM_UH @FinnGen_FI 21113
Reposted by Florian PrivéMichel Nivard @michelnivard.bsky.social · 19/05/2025This is VERY big genetics & health news, Regeneron (Pharmaceutical company with v strong genetics in medicine arm) is going to buy 23andme. investor.regeneron.com/news-release...investor.regeneron.com 23318
Reposted by Florian PrivéAlex Strudwick Young @alextisyoung.bsky.social · 28/04/2025I am recruiting a quantitative/computational postdoc to my group at UCLA. This is a great opportunity to work on foundational theory, methods, and software in statistical genetics. Link to apply: recruit.apo.ucla.edu/JPF10275. Please repost! 01217
Florian Privé @privefl.bsky.social · 10/04/2025Thanks! I actually use a few people from the 1000G as well, to get a few more people from Finland, Japan, and South America. In the future I would like to also add the Papuan from the SGDP. 100
Florian Privé @privefl.bsky.social · 10/04/2025✅ In this paper, I used the UK Biobank to define 18 reference worldwide populations, and provided a method to easily infer ancestry proportions of individuals from your study more accurately. Please have it a try! Paper: doi.org/10.1093/bioi... Tutorial: privefl.github.io/bigsnpr/arti... 281
Florian Privé @privefl.bsky.social · 10/04/2025👀 I still see many papers using the 1000G data to infer ancestry proportions of individuals in their respective studies. ❌ But I argue that the 1000G is not doing a very good job at covering well the worldwide populations. 143
Florian Privé @privefl.bsky.social · 07/04/2025Not sure. I think someone provided some VCF -> bed -> BGEN conversion. Not sure what is this DRAGEN. 100
Florian Privé @privefl.bsky.social · 07/04/2025Did they update the BGEN files they provide? Initially they were missing 30% of variants. 110
Reposted by Florian PrivéSMARTbiomed @smartbiomed.bsky.social · 02/04/2025📢 Applications open for the SMARTbiomed Summer School! 🧠 Learn Causal Inference, Statistical Genetics & ML in R 📍 June 23–27 at the stunning Sandbjerg Estate, Denmark ⏳ Apply by April 19 — limited spots available! 👩🔬 For PhDs, postdocs & early-career researchers 🔗 smartbiomed.dk/news-and-eve...smartbiomed.dk 176
Reposted by Florian PrivéBjarni Vilhjalmsson @bvilhjal.bsky.social · 25/03/2025Potential Main or Co-Supervisors include: Naomi Wray (Oxford), Peter Visscher (Oxford), Erin Gabriel (KU), Preben B Mortensen (AU), @eagerbo.bsky.social (AU), @privefl.bsky.social (AU), Thomas Gerds (KU), Julie Dreier (AU), and others. 141
Reposted by Florian PrivéInternational Society of Psychiatric Genetics @ispg.bsky.social · 23/03/2025Join us for the ISPG Members' Meetup on March 26th! Dr. Oliver Pain will present his groundbreaking research on polygenic scores and the innovative GenoPred pipeline. Don't miss out: us06web.zoom.us/meeting/regi... #ISPG #Genetics #PolygenicScores #Bioinformatics 077
Florian Privé @privefl.bsky.social · 18/03/2025I'll be there! This is a very affordable conference on Statistical Genetics methodologies 🤩 040
Reposted by Florian PrivéBjarni Vilhjalmsson @bvilhjal.bsky.social · 11/03/2025We're hiring Pioneer Fellow Postdocs!! Join us at the Pioneer Centre for SMARTbiomed to develop innovative methods in epidemiology, biostatistics, and statistical genetics, working with big biomedical data. international.au.dk/about/profil... #StatGen #Epi #Postdoc #SMARTbiomedinternational.au.dkPostdocs in Epidemiology or Statistical Genetics at The Pioneer Centre for SMARTbiomed - Vacancy at Aarhus UniversityVacancy at Department of Public Health - NCRR - National Centre for Register-based Research, Aarhus University 12112
Reposted by Florian PrivéSMARTbiomed @smartbiomed.bsky.social · 14/01/2025The Pioneer Centre for SMARTbiomed will leverage large-scale, multimodal biomedical data combined with focused innovation in statistical and computational methods including machine learning to advance our understanding, treatment, and prevention of human disease. Learn more about us: smartbiomed.dksmartbiomed.dkThe Pioneer Centre for SMARTbiomedThe Pioneer Centre is anchored at Aarhus University and will be a collaboration of researchers from Aarhus University, University of Copenhagen, and University of Oxford. 064
Reposted by Florian PrivéSMARTbiomed @smartbiomed.bsky.social · 14/01/2025Looking for a PhD position in statistical methods development for causality? Then we might be looking for you! jobportal.ku.dk/alle-opslag/...jobportal.ku.dkPhD fellowships in Biostatistics and Causal inference at the SMARTbiomed Pioneer centre 014
Reposted by Florian PrivéAnthony Herzig @anthony-herzig.bsky.social · 06/01/2025Abstract submissions for the European Mathematical Genetics Meeting are open! emgm2025.sciencesconf.org Deadline February 2nd, looking forward to seeing your proposals. Meeting is in Brest, France, 8-9 Aprilemgm2025.sciencesconf.org53rd European Mathematical Genetics Meeting - Sciencesconf.org 034
Florian Privé @privefl.bsky.social · 23/12/2024Genetic PCs rarely provide large % of variation, but I don’t think it means they’re not useful. Try to look at the loadings if possible. 100
Florian Privé @privefl.bsky.social · 22/12/2024Are there any peaks? Cf. privefl.github.io/bigsnpr/arti...privefl.github.ioHow to capture population structure with PCA? 221
Florian Privé @privefl.bsky.social · 22/12/2024I meant the looking of the PC scores. Did you look at the PC loadings? 100
Florian Privé @privefl.bsky.social · 22/12/2024The PCA is indeed a bit odd; are you sure you’re not capturing LD instead of population structure? 100
Reposted by Florian PrivéShai Carmi @shaicarmi.bsky.social · 24/11/2024Very interesting work by Tade Souaiaia et al on the non-polygenic architecture of the extremes of complex traits. For many traits, polygenic scores show "regression to the mean" around the tails, as extreme traits are mostly due to rare alleles. www.biorxiv.org/content/10.1... 14316