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Prism Science

@prismscienceorg.bsky.social
144 followers 25 following 51 posts

Prism is building the full stack of technologies and algorithms necessary to make protein motion measurable, actionable, and predictable. Learn more at prismscience.org

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Prism Science @prismscienceorg.bsky.social · 08/09/2026
Prism is building the full stack of technologies and algorithms necessary to make protein motion measurable, actionable, and predictable. Coordinated change to transform the field of structural biology.
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Prism Science @prismscienceorg.bsky.social · 08/09/2026
We need new ways to understand disease & design drugs. Protein motion holds the answer.
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Prism Science @prismscienceorg.bsky.social · 01/09/2026
Same mission, but an expanded vision for revolutionizing structural biology to better capture protein motion. Launching September 8.
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Prism Science @prismscienceorg.bsky.social · 21/08/2026
DiffUSE is rebuilding GOODVIBES, a forward model for lattice vibrations in diffuse scattering, in fully open-source Python that handles any space group or unit cell. Stephen Thornton posts the progress and open questions. diffuse.science/posts/goodvi... #openscience
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Prism Science @prismscienceorg.bsky.social · 11/08/2026
We ran qFit across high-resolution PDB entries with deposited structure factors: 60,000+ ensemble models, the largest experimentally derived set to date. 83.7% fit the data better than the deposited structure, surfacing side-chain heterogeneity that single models miss.
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Prism Science @prismscienceorg.bsky.social · 22/07/2026
New TTPD episode discusses two bioRxiv preprints, revisits the Bethesda Declaration one year on, and public pushback to the OMB funding rule. Plus: where blogs end and peer review begins. diffuse.science/posts/TTPD-16/ #StructuralBiology #Biophysics #OpenScience
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Prism Science @prismscienceorg.bsky.social · 30/06/2026
Open science is useful science. One effort we are developing are logbooks where we share research as it happens: what works, what doesn't, what we've learned. Led by DiffUSE Scientist Steve Meisburger (@meisborg.bsky.social). See the latest: diffuse.science/logbook/beam... #OpenScience
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Prism Science @prismscienceorg.bsky.social · 29/06/2026
What's happening in protein dynamics research right now? Jaime & Stephanie break down NIH policy changes, preprints & the conformational ensembles conference. New episode up: diffuse.science/posts/TTPD-15/ #StructuralBiology
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Prism Science @prismscienceorg.bsky.social · 15/06/2026
See our most recent blog diffuse.science/post/science... #SciComm #OpenScience
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Prism Science @prismscienceorg.bsky.social · 09/06/2026
We present sampleworks, an open, modular platform for generating and evaluating biomolecular conformational ensembles from structure predictors guided by experimental data doi.org/10.82153/jkx....
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Prism Science @prismscienceorg.bsky.social · 13/05/2026
ICYMI: The latest Tortured Proteins Department episode. @stephanieaw.bsky.social and @fraserlab.com on: NIH strategic plan comments (due 5/26), AI lab guidelines, two new cryo-EM preprints, training scientists for what's next diffuse.science/posts/TTPD-14/
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Prism Science @prismscienceorg.bsky.social · 26/02/2026
Tomorrow (2/27) 3 pm ET, DiffUSE Project Scientist Steve Meisburger presents "Diffuse Scattering Wars (Episode IV): A New Hope for Structural Biology" Learn how diffuse scattering could reveal what AI structure predictors are missing. Join here: www.chess.cornell.edu/science/ches...
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