iiinova — where your digital self keeps evolving

Reposted by Steve Meisburger

Prism Science @prismscienceorg.bsky.social · 04/09/2026

Diffuse scattering is hard to compare quantitatively across experiments, let alone across synchrotrons. A new DiffUSE Project update shows diffuse maps reproducing across CHESS and ALS. Read the project update: diffuse.science/posts/reprod...

diffuse.science

Coffee is for Closers: making Mac1 diffuse scattering reproducible

diffuse scattering reproducible, yay!

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Reposted by Steve Meisburger

Prism Science @prismscienceorg.bsky.social · 03/09/2026

Diffuse scattering can encode correlated protein motions, but standard pipelines often discard it as background. mdx2 is an open-source Python toolkit for carrying that signal through processing. Read @meisborg.bsky.social's overview and try mdx2: diffuse.science/posts/mdx2/

diffuse.science

Revealing hidden signals in raw X-ray crystallography data with mdx2

Mdx2 is a powerful and open-source toolkit for diffuse data processing.

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Reposted by Steve Meisburger

Prism Science @prismscienceorg.bsky.social · 30/06/2026

Open science is useful science. One effort we are developing are logbooks where we share research as it happens: what works, what doesn't, what we've learned. Led by DiffUSE Scientist Steve Meisburger (@meisborg.bsky.social). See the latest: diffuse.science/logbook/beam... #OpenScience

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Reposted by Steve Meisburger

Prism Science @prismscienceorg.bsky.social · 03/03/2026

MD simulations show that diffuse scattering patterns shift depending on whether ligand or a buffer molecule occupies the binding pocket. The differences are quantitatively significant, a promising sign that experiments could detect these changes. Read more: diffuse.science/post/shake-i...

diffuse.science

Shake It Up!

MD simulations of changes in diffuse scattering depending on ligand binding

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Reposted by Steve Meisburger

Prism Science @prismscienceorg.bsky.social · 26/02/2026

Tomorrow (2/27) 3 pm ET, DiffUSE Project Scientist Steve Meisburger presents "Diffuse Scattering Wars (Episode IV): A New Hope for Structural Biology" Learn how diffuse scattering could reveal what AI structure predictors are missing. Join here: www.chess.cornell.edu/science/ches...

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Reposted by Steve Meisburger

Nozomi Ando @nozomi-ando.bsky.social · 06/11/2025

@andolab.bsky.social undergrads at the beamline! Here are Marcus, Katie, Sarah, and Shaheer collecting data for @diffuseproject.bsky.social with @meisborg.bsky.social and @xiaokunpei.bsky.social 😎💥

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Reposted by Steve Meisburger

Seemay Chou @seemaychou.bsky.social · 21/10/2025

I spend a lot of time talking to potential grantees about our open science policy. Some field notes here: open.substack.com/pub/seemay/p...

open.substack.com

Why careerism can be bad for science training

Some field notes from scholarly publishing discussions with scientists

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Reposted by Steve Meisburger

Prism Science @prismscienceorg.bsky.social · 07/10/2025

The Diffuse Project is looking for an amazing Project Manager to help us achieve our goal of unlocking protein dynamics! Are you a scientist who naturally loves organization, coordination, problem solving and working with a diverse team of scientists & engineers?

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