New Service Empowers Clinicians with Personalized Insights from Coriell Life Sciences to Optimize Prescribing Across Specialties SECAUCUS, N.J., Sept. 4, 2025 /PRNewswire/ -- Quest Diagnostics...

Genetic variation within intron 3 of the CACNA1C calcium channel gene is associated with schizophrenia and other neuropsychiatric disorders, but an...

GeneAgent is a language agent using large language models and self-verification to improve gene-set function annotation.

Research grant contest to improve how epigenetics can impact disease using DNA methylation studies.

Epigenome association study of father’s preconception body silhouette with offspring DNA methylation, providing mechanistic insight into how epigenetic inheritance impacts offspring obesity, asthma an...

The phase 2 ROME trial demonstrated that combining tissue and liquid biopsies to guide tailored therapy in advanced solid tumors significantly improves survival outcomes compared to standard of care o...

Ovation is a genomic data company committed to unlocking the potential of human genomic data to accelerate precision medicine. By generating high-quality genomic data linked to rich, longitudinal phen...

Kabuki syndrome type 1 (KS1) is a monogenic disorder arising from pathogenic variants within KMT2D and characterized by syndromic neurodevelopmental delay. We report the retrospective identification o...

The delay for Stealth Biotherapeutics comes amid a heightened focus on the impact FDA job cuts might have on drug reviews.

The science of aging, geroscience, translates to its medical application, or geromedicine. This transition will be facilitated by systematic omics technologies quantifying pro-aging (gerogenic) and an...

The suggestion that pathogens play a part in driving dementia is not as niche as it once was, but the evidence remains inconclusive.

A novel antiviral targeting the SARS-CoV-2 PLpro protease shows strong efficacy in a mouse model, preventing lung pathology and reducing brain dysfunction. The study provides proof-of-principle that P...

Labcorp's pTau-217/Beta Amyloid 42 Ratio blood test meets the performance criteria to confirm amyloid pathology consistent with Alzheimer's disease BURLINGTON, N.C. , April 2, 2025 /PRNewswire/ -- Lab...

Providers can use combinatorial pharmacogenomic panels to aid psychiatric medication prescribing. Results are typically documented in static documents which list the genotype and predicted phenotyp...

Delivery of autoimmune disease–associated antibodies activates the immune system to fight glioblastomas.

COVID-19 vaccines have prevented millions of COVID-19 deaths. Yet, a small fraction of the population reports a chronic debilitating condition after COVID-19 vaccination, often referred to as post- va...

New systems can identify unknown proteins in samples from diseased tissue, the environment, and archaeological sites

Earlier this month, Ian Lipkin, M.D., and his team at Columbia University submitted a paper for publication that suggests certain approved drugs could possibly be repurposed for a severe fatigue co | ...

Dr Ben Sinclair battled long Covid before opening specialist clinics to help other sufferers

Read about Bing Ren Appointed Scientific Director and Chief Executive Officer of the New York Genome Center at the New York Genome Center on March 27, 2025

Long-read sequencing technologies can directly profile methylation modifications across the genome. In this Review, Fu et al. overview the long-read computational tools to identify and compare methyla...

In a survey of AI researchers, most say current AI models are unlikely to lead to artificial general intelligence with human-level capabilities, even as companies invest billions of dollars in this go...

Ellrott et al. provide a means to assign patient samples from clinical trials and other cancer genome studies to published TCGA molecular subtypes. Applying machine learning to data from five differen...

Nanopore and PacBio are generally considered free from sequence composition bias, a key factor—alongside read length—that explains their success in producing high quality genome assemblies. However, o...

Overall, by harnessing the specificity and efficacy of ASOs, we present an effective and adaptable therapeutic platform for NSCLC treatment.

Scientists at UC San Francisco have developed a revolutionary cancer treatment that precisely targets tumors with radiation while sparing healthy tissues. By using a KRAS-targeting drug to mark cancer...

European Journal of Applied Physiology -

We tested the within-person comparability of common epigenetic clocks across five tissue types: buccal epithelial, saliva, dry blood spots, buffy coat (i.e., leukocytes), and peripheral blood mononuc...

Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) patients share similar symptoms including post-exertional malaise, neurocognitive impairment, and memory loss. The neurocogni...

We developed an AI-based method that can provide an accurate, timely, and economical prediction of gene mutation and mutation spatial distribution. The method showed substantial potential as an assist...

Recent drug approvals show small and medium-sized players are becoming increasingly successful at navigating the obstacles to get precision therapies acros...

NIH has an historic opportunity to transform post-viral illness research by bringing ME/CFS into its long Covid RECOVER Initiative.

Using multiple datasets from real-world evidence and completed trials, a machine learning model using routine blood and clinical data is shown to be predictive of patient response to immune checkpoint...

Our study highlights that national-scale EHRs provide a unique resource to estimate detailed prevalence, clinical, and demographic data for rare diseases. Using COVID-19-related mortality analysis, we...

The landscape of psychiatric care is poised for transformation through the integration of pharmaco-multiomics, encompassing genomics, proteomics, metabolomics, transcriptomics, epigenomics, and microb...

Background/Objectives: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex neuroimmunological disorder with limited treatment options. Despite the widespread use of Dietary Supple...

In a population-based cohort of 191 children with diverse solid tumors, systems-level analyses unravel immune variation with age and tumor type and provide a reference for future precision immunothera...

npj Digital Medicine - Convergence of evolving artificial intelligence and machine learning techniques in precision oncology

UK oncology researchers have come together to write the first ever national thought leadership strategy report into cancer vaccine advances and the opportunities these present for those affected by ca...

15Background: BESPOKE CRC, a multicenter, prospective, observational study investigated the clinical utility of ctDNA for detecting MRD-based early recurrence in pts with surgically resected CRC. The ...

I think of you all every day as I work to untangle the complex molecular basis of this horrific disease…I am very optimistic that soon the major mechanisms that initiate the disease will be found. Thi...

Pediatric Research - Distinct pro-inflammatory/pro-angiogenetic signatures distinguish children with Long COVID from controls

This cohort study examines whether there are differences in the risk of developing long COVID, or post-COVID condition, by sex.

npj Digital Medicine - Computational frameworks transform antagonism to synergy in optimizing combination therapies