Sign in

Pranavathiyani G

@pranavathiyani.bsky.social
359 followers 1.1K following 25 posts

Assistant Professor (Research) at SASTRA University | Multidisciplinary enthusiast 💬 | #Bioinformatics #SystemsBiology #DataScience #AMR #Coding #AI

PostsRepliesMedia
Reposted by Pranavathiyani G
Nobel Prize @nobelprize.org · 18h
BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
16973477
Pranavathiyani G @pranavathiyani.bsky.social · 04/10/2026
Can you name the women who have won a science Nobel prize? Take @nature.com quiz on female @Nobel laureates in physics, chemistry or physiology or medicine. @nobelprize.org www.nature.com/articles/d41... #NobelPrizeWeek2026
nature.com
Can you name the women who have won a science Nobel prize?
Take Nature’s quiz on female Nobel laureates in physics, chemistry or physiology or medicine.
010
Reposted by Pranavathiyani G
Nature Reviews Drug Discovery @natrevdrugdiscov.nature.com · 20/04/2026
Target identification and assessment in the era of AI rdcu.be/fep9Z www.nature.com/articles/s41... This new Review analyses advances in applying AI-driven approaches for therapeutic target exploration, and discusses how to address challenges and limitations in the field
Stages at which different AI models are used in drug target identification and assessment
031
Reposted by Pranavathiyani G
Galaxy Project @galaxyproject.bsky.social · 18/03/2026
Registration is now OPEN for the 2026 Galaxy Training Academy! A free, global week of hands-on training in: 🧬 Proteomics | 🧩 Assembly | 🧫 Transcriptomics 🔬 Single cell | 🌍 Climate | 🤖 Machine learning + more 🗓 May 18–22 Learn more and register here: gxy.io/GTA2026-info
Banner announcing that registration is now open for the Galaxy Training Academy. Text reads “Galaxy Training Academy” with dates May 18–22, 2026 and “Free Virtual Course,” along with the link gxy.io/GTA2026-info. The design features a blue background and an illustration of a person wearing headphones working on a laptop inside a yellow circular graphic.
054
Reposted by Pranavathiyani G
EMBL-EBI @ebi.embl.org · 26/02/2026
📢 We want your feedback on our new pilot project for sharing AI models in life science research. Finding, reusing and citing machine learning models remains a major challenge in the life sciences. BioAIrepo is here to help. www.ebi.ac.uk/about/news/t...
ebi.ac.uk
BioAIrepo: EMBL-EBI’s hub for life science AI models
New EMBL-EBI repository helps researchers share and reuse machine learning models trained on life science data.
1168
Reposted by Pranavathiyani G
Protein Data Bank in Europe (PDBe) @pdbeurope.bsky.social · 21/10/2025
AlphaFold DB v6 (synced with UniProt 2025_03) is live! Here are the details: Totals v4 → v6: 241,070,489 entries. Since v4: +65,711,653 added, 39,324,993 removed, 276,539 changed (in sequence), 175,082,297 unchanged (metadata refresh, relabelled v6). Details 👇
194
Reposted by Pranavathiyani G
Posit @posit.co · 17/09/2025
📣 HUGE ANNOUNCEMENT! Drum roll please 🥁🥁🥁🥁🥁🥁🥁 Introducing Positron, a free code editor built specifically for data science. Learn more about what you can do with Positron: posit.co/blog/positro...
2527
Reposted by Pranavathiyani G
FEMS @femsmicro.org · 17/09/2025
For #InternationalMicroorganismDay, we asked our FEMS MICRO 2025 Keynote Speakers and FEMS Journal Editors "'What is your favourite microbe?'' With delightful answers, ranging over many microbes and personal stories, this was the perfect way to celebrate IMD 2025! #MicroSky youtu.be/oEJsWNJCtBw
youtu.be
Favourite Microbes for International Microorganism Day 2025
YouTube video by FEMS Microbiology
074
Reposted by Pranavathiyani G
Antimicrobial resistance #AMR @antimicrobial.bsky.social · 13/09/2025
Today on World Sepsis Day, neonatal sepsis remains a major killer, taking over 400,000 newborn lives each year, driven by weak immunity, delayed care, and #AMR. Strengthening hygiene, diagnostics, and timely treatment is crucial to closing the survival gap. www.financialexpress.com/life/health/...
financialexpress.com
World Sepsis Day 2025: 400,000 babies die each year from this silent infection—Can it be stopped?
World Sepsis Day 2025: Sepsis is a silent infection that takes 400,000 newborn lives every year. Weak immunity, delayed treatment, and drug resistance make it harder to save babies.
01913
Pranavathiyani G @pranavathiyani.bsky.social · 11/09/2025
Ten simple rules for navigating #AI in #Science @plos.org
010
Reposted by Pranavathiyani G
Protein Data Bank in Europe (PDBe) @pdbeurope.bsky.social · 11/09/2025
🧪 We're beta testing – and we want your thoughts! Try the new PDBe-KB Complex pages and let us know: 🔸 What’s working? 🔸 What’s confusing? 🔸 What features are lacking 💬 Feedback form: tinyurl.com/pdbekb-compl... #PDBeKB #Complexes #Bioinformatics #StructuralBiology #Science
064
Pranavathiyani G @pranavathiyani.bsky.social · 30/07/2025
Virtual Lab #AI www.czbiohub.org/news/with-no...
czbiohub.org
AI-built ‘scientists’ get the job done quickly
In Virtual Lab project, CZ Biohub San Francisco researchers and collaborators assemble team of interdisciplinary AI agents that can solve complex research questions
030
Reposted by Pranavathiyani G
Javier Santoyo @jsantoyo.bsky.social · 23/07/2025
PhyloScape: interactive and scalable visualization platform for phylogenetic trees. r#PhylogeneticTees #Visualization #Bioinformatics #BMCbioinformatics bmcbioinformatics.biomedcentral.com/articles/10....
041
Reposted by Pranavathiyani G
Stephen Turner @stephenturner.us · 22/07/2025
Genomic reproducibility in the bioinformatics era genomebiology.biomedcentral.com/articles/10.... 🧬🖥️
153
Reposted by Pranavathiyani G
Stephen Turner @stephenturner.us · 11/07/2025
Exploring R and Rust in Bioinformatics - online developer forum blog.bioconductor.org/posts/2025-0... #Rstats #rustlang
072
Pranavathiyani G @pranavathiyani.bsky.social · 25/06/2025
#AlphaGenome: #AI for better understanding the #genome deepmind.google/discover/blo...
deepmind.google
AlphaGenome: AI for better understanding the genome
Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API.
052
Pranavathiyani G @pranavathiyani.bsky.social · 10/05/2025
Tissue specific protein-protein associations #atlas #ppi #disesse
nature.com
A tissue-specific atlas of protein–protein associations enables prioritization of candidate disease genes - Nature Biotechnology
Protein–protein interactions specific to 11 individual tissues are presented in a comprehensive resource.
000
Pranavathiyani G @pranavathiyani.bsky.social · 09/05/2025
#Candida auris - emerging pathogen of #UTI
journals.plos.org
Candida auris is emerging as a prevalent urinary pathogen
Urinary tract infections (UTIs) are one of the most common infections, with a subgroup of these infections, catheter-associated UTIs (CAUTIs), accounting for 40% of nosocomial infections. While the ma...
000
Reposted by Pranavathiyani G
Zoe Anne Dyson @msmicrobiocode.bsky.social · 09/05/2025
🧬 Out today 🧬 - our TyphiNET #AMR surveillance dashboard for #typhoid Use TyphiNET to view genome-derived data on global and national annual trends in AMR and circulating pathogen genotypes via any standard web browser. genomemedicine.biomedcentral.com/articles/10....
genomemedicine.biomedcentral.com
The TyphiNET data visualisation dashboard: unlocking Salmonella Typhi genomics data to support public health - Genome Medicine
Background Salmonella enterica subspecies enterica serovar Typhi (abbreviated as ‘Typhi’) is the bacterial agent of typhoid fever. Effective antimicrobial therapy reduces complications and mortality; ...
2137
Pranavathiyani G @pranavathiyani.bsky.social · 23/04/2025
#Programming for research
nature.com
Which programming language should I use? A guide for early-career researchers
Computer scientists and bioinformaticians address four key questions to help rookie coders to make the right choice.
010
Pranavathiyani G @pranavathiyani.bsky.social · 11/03/2025
Margaret Dayhoff! #Bioinformatics www.nature.com/articles/s43...
nature.com
Celebrating a pioneer in bioinformatics - Nature Computational Science
In honor of the 100th birthday of Margaret Dayhoff, we spotlight her footprint in the field of bioinformatics.
031
Reposted by Pranavathiyani G
Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 20/01/2025
Foldseek 10 with 4-27x (1-8 GPUs) faster search through MMseqs2-GPU. Faster ProstT5 protein search w/o structure prediction through multi-GPU/Apple Metal, new BFVD/BFMD databases and multimer clustering (preview). 💾 github.com/steineggerla... 📄 www.biorxiv.org/content/10.1... 🐍 available in bioconda
17824
Pranavathiyani G @pranavathiyani.bsky.social · 04/12/2024
#KlebPhaCol www.biorxiv.org/content/10.1... #klebsiella #phage
biorxiv.org
KlebPhaCol: A community-driven resource for Klebsiella research identified a novel gut phage order associated with the human gut
The growing threat of multidrug-resistant Klebsiella pneumoniae, coupled with its role in gut colonisation, has intensified the search for new treatments, including bacteriophage therapy. Despite incr...
100
Pranavathiyani G @pranavathiyani.bsky.social · 03/12/2024
Bacteria’s Stress Strategy: Slow Down to Avoid the Crowd www.the-scientist.com/bacteria-s-s... #bacteria #stress #simulation
the-scientist.com
Bacteria’s Stress Strategy: Slow Down to Avoid the Crowd
Computer simulations highlight how bacteria slow their growth to avoid overcrowding, a behavior that may inform pathogen control.
000
Pranavathiyani G @pranavathiyani.bsky.social · 02/12/2024
www.ipd.uw.edu/2024/11/intr... #peptidedesign #diffusion
ipd.uw.edu
Introducing RFpeptides - Institute for Protein Design
Generative AI based on RFdiffusion designs cyclic peptides with atomic accuracy.
010
Pranavathiyani G @pranavathiyani.bsky.social · 30/11/2024
www.nature.com/articles/d41... #longevity #aging
nature.com
What’s the secret to living to 100? Centenarian stem cells could offer clues
A bank of cells from people more than 100 years old gives scientists a new resource for studying longevity.
000
Pranavathiyani G @pranavathiyani.bsky.social · 29/11/2024
Language Models for Molecular Dynamics www.biorxiv.org/content/10.1... #languagemodel #moleculardynamics
biorxiv.org
Language Models for Molecular Dynamics
Molecular Dynamics (MD) simulations provide accurate descriptions of the motions of molecular systems, yet their computational demands pose significant challenges in applications in molecular biology ...
000
Reposted by Pranavathiyani G
bioRxiv Bioinfo @biorxiv-bioinfo.bsky.social · 29/11/2024
EasyPubPlot: a shiny web application for rapid omics data exploration and visualization www.biorxiv.org/content/10.1101/202…
biorxiv.org
EasyPubPlot: a shiny web application for rapid omics data exploration and visualization https://www.biorxiv.org/content/10.1101/2024.11.26.625339v1
Computational toolkits for data exploration and visualization from widely used omics platforms often
021
Reposted by Pranavathiyani G
Gabriele Corso @gcorso.bsky.social · 28/11/2024
We’re excited to release a major update to the Boltz repo: v0.3.0. This release contains several important new features, including our confidence model and memory-efficient inference. Give it a try! github.com/jwohlwend/bo...
github.com
GitHub - jwohlwend/boltz: Official repository for the Boltz-1 biomolecular interaction model
Official repository for the Boltz-1 biomolecular interaction model - jwohlwend/boltz
27113
Reposted by Pranavathiyani G
Milot Mirdita @milot.bsky.social · 27/11/2024
MMseqs2 Release 16 Highlights: GPU-accelerated search📄, ORF or new 6-frame translated search modes, contig taxonomy always keeps the longest ORF, bug fixes (reduced memory and higher sensitivity) and relicensed as MIT 📄 biorxiv.org/content/10.1... 💾 mmseqs.com and 🐍Bioconda 🖥️🧬🧶
Promotional logo for MMseqs2 16 with the MMseqs2 Rocket mascot as a smart phone like App logo
011443
Pranavathiyani G @pranavathiyani.bsky.social · 26/11/2024
#NetworkCommons: bridging data, knowledge and methods to build and evaluate context-specific biological #networks www.biorxiv.org/content/10.1...
biorxiv.org
NetworkCommons: bridging data, knowledge and methods to build and evaluate context-specific biological networks
Summary: We present NetworkCommons, a platform for integrating prior knowledge, omics data, and network inference methods, facilitating their usage and evaluation. NetworkCommons aims to be an infrast...
100
Reposted by Pranavathiyani G
Cameron Thrash @jcamthrash.bsky.social · 19/11/2024
UniProt: the Universal Protein Knowledgebase in 2025 academic.oup.com/nar/advance-... #jcampubs
academic.oup.com
UniProt: the Universal Protein Knowledgebase in 2025
Abstract. The aim of the UniProt Knowledgebase (UniProtKB; https://www.uniprot.org/) is to provide users with a comprehensive, high-quality and freely acce
0196
Pranavathiyani G @pranavathiyani.bsky.social · 23/11/2024
#WhatIsMyGene: Back to the Basics of Gene Enrichment www.biorxiv.org/content/10.1... #enrichment #genes
biorxiv.org
WhatIsMyGene: Back to the Basics of Gene Enrichment
Since its inception over 20 years ago, gene enrichment has been largely associated with curated gene lists (e.g. GO) that are constructed to represent various biological concepts; the cell cycle, canc...
010
Pranavathiyani G @pranavathiyani.bsky.social · 22/11/2024
#PanTax: Strain-level taxonomic classification of metagenomic data using #pangenome graphs www.biorxiv.org/content/10.1... #microbiome #metagenomics #taxonomy
biorxiv.org
PanTax: Strain-level taxonomic classification of metagenomic data using pangenome graphs
Microbes are omnipresent, thriving in a range of habitats from oceans to soils and even within our gastrointestinal tracts. They play a vital role in maintaining ecological equilibrium and promoting t...
063
Reposted by Pranavathiyani G
Kourosh Kalantar-Zadeh @kouroshkalantar.bsky.social · 20/11/2024
Your friends shape your microbiome — and so do their friends Analysis of nearly 2,000 people living in remote villages in Honduras reveals who’s spreading gut microorganisms to whom. www.nature.com/articles/d41...
082
Pranavathiyani G @pranavathiyani.bsky.social · 22/11/2024
#Harmonizome 3.0: integrated knowledge about genes and proteins from diverse multi-omics resources academic.oup.com/nar/advance-... #knowledgegraph #multiomics #genes #data #llm
academic.oup.com
Harmonizome 3.0: integrated knowledge about genes and proteins from diverse multi-omics resources
Abstract. By processing and abstracting diverse omics datasets into associations between genes and their attributes, the Harmonizome database enables resea
000
Pranavathiyani G @pranavathiyani.bsky.social · 22/11/2024
#Gaia: A Context-Aware #Sequence Search and Discovery Tool for Microbial #Proteins www.biorxiv.org/content/10.1... #languagemodel #llm
biorxiv.org
Gaia: A Context-Aware Sequence Search and Discovery Tool for Microbial Proteins
Protein sequence similarity search is fundamental to genomics research, but current methods are typically not able to consider crucial genomic context information that can be indicative of protein fun...
000
Reposted by Pranavathiyani G
bioRxivpreprint @biorxivpreprint.bsky.social · 21/11/2024
CellBinDB: A Large-Scale Multimodal Annotated Dataset for Cell Segmentation with Benchmarking of Universal Models www.biorxiv.org/content/10.1101/202…
biorxiv.org
CellBinDB: A Large-Scale Multimodal Annotated Dataset for Cell Segmentation with Benchmarking of Universal Models https://www.biorxiv.org/content/10.1101/2024.11.20.619750v1
In recent years, advances in cell segmentation techniques have played a critical role in the analysi
011
Pranavathiyani G @pranavathiyani.bsky.social · 21/11/2024
What is the real value of #omics data? Enhancing #research outcomes and securing long-term data excellence academic.oup.com/nar/article/...
academic.oup.com
What is the real value of omics data? Enhancing research outcomes and securing long-term data excellence
Abstract. A wealth of high-throughput biological data, of which omics constitute a significant fraction, has been made publicly available in repositories o
011
Pranavathiyani G @pranavathiyani.bsky.social · 21/11/2024
#AI-readiness for #Biomedical Data: Bridge2AI Recommendations www.biorxiv.org/content/10.1...
biorxiv.org
AI-readiness for Biomedical Data: Bridge2AI Recommendations
Biomedical research and clinical practice are in the midst of a transition toward significantly increased use of artificial intelligence (AI) and machine learning (ML) methods. These advances promise ...
010
Pranavathiyani G @pranavathiyani.bsky.social · 21/11/2024
Global ocean #microbiome catalogue: A gateway to unlock marine microbial resources and #ecosystem functions www.the-innovation.org/article/doi/...
the-innovation.org
Global ocean microbiome catalogue: A gateway to unlock marine microbial resources and ecosystem functions
010
Pranavathiyani G @pranavathiyani.bsky.social · 21/11/2024
#Boltz-1: Democratizing Biomolecular Interaction Modeling www.biorxiv.org/content/10.1... #biomolecules #interactions
biorxiv.org
Boltz-1: Democratizing Biomolecular Interaction Modeling
Understanding biomolecular interactions is fundamental to advancing fields like drug discovery and protein design. In this paper, we introduce Boltz-1, an open-source deep learning model incorporating...
010
Reposted by Pranavathiyani G
Leo Zang @leozang.bsky.social · 21/11/2024
Database updates -The Pfam protein families database: embracing AI/ML academic.oup.com/nar/advance-... - UniProt: the Universal Protein Knowledgebase in 2025 academic.oup.com/nar/advance-... - RASP v2.0: an updated atlas for RNA structure probing data academic.oup.com/nar/advance-...
academic.oup.com
UniProt: the Universal Protein Knowledgebase in 2025
Abstract. The aim of the UniProt Knowledgebase (UniProtKB; https://www.uniprot.org/) is to provide users with a comprehensive, high-quality and freely acce
1163
Reposted by Pranavathiyani G
Kyle Tretina @allthingsapx.bsky.social · 19/11/2024
If you're building AI models for drug discovery, you should check out the newly open-source #BioNeMo Framework: code: github.com/NVIDIA/bione... paper: arxiv.org/abs/2411.10548 docs: docs.nvidia.com/bionemo-fram... explainer: t.co/7MOamSChGN
github.com
GitHub - NVIDIA/bionemo-framework: BioNeMo Framework: For building and adapting AI models in drug discovery at scale
BioNeMo Framework: For building and adapting AI models in drug discovery at scale - NVIDIA/bionemo-framework
094
Reposted by Pranavathiyani G
Javier Santoyo @jsantoyo.bsky.social · 19/11/2024
APAtizer: a tool for alternative polyadenylation analysis of RNA-Seq data. #PolyA #AlternativePolyadenylation #RNAseq #Sequencing #Bioinformatics 🧬 🖥️ academic.oup.com/bioinformati...
academic.oup.com
APAtizer: a tool for alternative polyadenylation analysis of RNA-Seq data
AbstractSummary. APAtizer is a tool designed to analyze alternative polyadenylation events on RNA-sequencing data. The tool handles different file formats,
081
Pranavathiyani G @pranavathiyani.bsky.social · 14/11/2024
All about #Bioinformatics! go.bsky.app/ExYDQFv
360