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SMT

@pp0196.bsky.social
494 followers 787 following 538 posts

Sequences and consequences. Credit Pic : Cellular landscape cross-section through a eukaryotic cell, by Evan Ingersoll

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troy_phd @troyhernandez.bsky.social · 22/09/2026
Update: corteza scored 100% on ARC-AGI-3's public set with GPT-6 Astra! And due to how they calculate their metrics, I'm happy to report that our 100% is the best 100%. I made a dashboard with details: cornball.ai/arc-agi-3/ #rstats
cornball.ai
ARC-AGI-3 comparison
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SMT @pp0196.bsky.social · 20/09/2026
The truism that LLMs are LITERALLY stochastic parrots continues to butt-hurt some people. Why bother? You're literally operationalizing it through resampling, branching, verification, and search a.k.a. “agents”. Just show the promised value. Cure cancer. Long live Chinchilla!
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SMT @pp0196.bsky.social · 20/09/2026
#RStats heads-up CRAN Macos binaries are zstd compressed now (at least for some recently built ones, including knitr), this might break some CI setups github.com/r-lib/pkgdep...
github.com
Support zstd-compressed package archives: CRAN's current macOS binaries fail with "unknown archive type" · Issue #485 · r-lib/pkgdepends
Request Please recognize zstd-compressed tarballs in detect_package_archive_type(). CRAN's macOS builder has started compressing .tgz binaries with zstd, and pkgdepends rejects those archives befor...
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Gabor Csardi @gaborcsardi.org · 14/09/2026
New beta of #Rstats rig: LOTS of EXCITING stuff: - new: web site: rig.r-lib.org - new: user-mode R installation: rig.r-lib.org/admin-vs-use... - new: manage R packages (CRAN + git): rig.r-lib.org/pkg-guide.html - new: manage R projects and virtual environments: rig.r-lib.org/proj-guide.h...
rig.r-lib.org
rig – the R Installation Manager – rig
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SMT @pp0196.bsky.social · 12/09/2026
CanardAbsurd: Durable #RStats workflows with DuckDB state and Quack remote SQL (Slop) Sloppy attempt to solve some recurring issues around durability (and resumption) especially for (frontend or api) exposed (costly) workflow coordination. repo: github.com/RGenomicsETL...
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Heng Li @lh3lh3.bsky.social · 23/03/2026
Long reads carry multiple small vars and SVs and their phasing. LongcallD is the only caller that tightly integrates germline/mosaic small/structural vars/MEIs and their phasing in a single C program. One command line to get competitive small variant calls and better SVs. Led by Yan Gao.
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Miles McBain @milesmcbain.bsky.social · 09/09/2026
Big difference is obviously macros. But they worked damned hard to keep “the code is just data” philosophy that underpins macros.
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Vini @vinimdocarmo.com · 24/03/2025
Well, it's now backed by S3 and I've made the code public for anyone interested: github.com/vinimdocarmo... 🦆
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Henrik Bengtsson @henrikbengtsson.bsky.social · 21/08/2026
The Futureverse Resource Specification proposal: a syntax for resource declarations, monitoring & scheduling; fits <- map(xs, model_fit) |> resources(\(x) memory(4*object.size(x))) |> futurize() www.jottr.org/2026/08/11/r... #RStats #parallel #hpc
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DuckDB @duckdb.org · 17/08/2026
Quack, quack! A DuckDB v2.0 preview is here! 🦆 In this post, #DuckDB co-creators Mark Raasveldt + @hannes.muehleisen.org preview the headline features of DuckDB v2.0 (expected to land this autumn): • DuckDB as a server • Triggers • async I/O • + more Dive into the deets: duckdb.org/2026/08/17/d...
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Eddie Ruiz @ed2uiz.bsky.social · 14/08/2026
Can databases scale scientific analyses beyond RAM? I’m excited to share dbverse, a composable database framework built to do just that. Across benchmarks, dbverse delivers ~1000x speedups and scales #spatialomics analyses to millions of cells. Preprint: www.biorxiv.org/content/10.6... 1/🧵
biorxiv.org
dbverse scales spatial omics analysis with embedded analytical databases
Spatial omics datasets are increasing in size and complexity, exceeding the memory of standard computers and thereby limiting data analysis. Here we present dbverse, a framework for larger-than memory...
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troy_phd @troyhernandez.bsky.social · 14/08/2026
diffuseR is on CRAN! AI images and video, locally in #rstats install.packages("diffuseR") Go make something weird!
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SMT @pp0196.bsky.social · 11/08/2026
No matter how much one tries, LLMs cannot stop generating disgusting #Rstats code (1K .something functions checking if string is empty or similar) and i think this is getting worse. No wonder people do not want to read code anymore or prefer using slop language they don't know to read
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Tim Dunn @timd.one · 22/07/2026
CRISPR off-target search can find the right locus while hiding plausible alignments within it. I wrote about how Sassy v0.2.5 uses recursive backtracking to report every reasonable alignment—more than 9× as many in under 30 seconds. blog.fulcrumgenomics.com/p/why-crispr...
blog.fulcrumgenomics.com
Why CRISPR Off-Target Search Should Report Multiple Alignments Per Locus
How Sassy enumerates every reasonable alignment without sacrificing runtime
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SMT @pp0196.bsky.social · 29/07/2026
Even though i am a user of slopware, i thing the #Bioinformatics field needs a declaration like this leidendeclaration.ai
leidendeclaration.ai
Leiden Declaration on Artificial Intelligence and Mathematics
This declaration calls for action to address the challenges posed by the use of artificial intelligence within mathematics research.
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SMT @pp0196.bsky.social · 28/07/2026
#CRAN Release of version 1.5.1-0.1.3 of Rduckhts: #RStats Bindings to the #htslib based #DuckDB extension for HTS file formats This comes with a BigWig reader via libBigWig used with (WIP)DuckVEP: the fastest Ensembl VEP-compatible consequence predictor in the West written in #C #Bioinformatics
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SMT @pp0196.bsky.social · 25/07/2026
#RStats is this SSL issue on cran.r-project.org/submit.html restricted to me or others are facing the same issue ?
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SMT @pp0196.bsky.social · 18/07/2026
#Rstats ah looks like CRAN fedora machine's tool chain got updated, and lot of C code nonsense in the vendored libraries my packages wrap are not allowed anymore. Good though that there are 25 other packages concerned :D I have on month to fix it or packages will be rightfully boot out
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SMT @pp0196.bsky.social · 14/07/2026
best way to send a LLM into a loop and burn all your tokens, in #RStats/C project, say go look at @coolbutuseless.bsky.social repos github.com/coolbutusele... for what we can use
github.com
coolbutuseless - Repositories
Cool, but useless. coolbutuseless has 255 repositories available. Follow their code on GitHub.
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SMT @pp0196.bsky.social · 10/07/2026
CRAN release of version 1.4.0-0.1.0 of Rduckhts, the #RStats It was also nice to confirm that are our port of Brent Pedersen 's great mostdepth algorithm is likely the fastest for that application space in the West. But riker shows us there is space for memory bounding !
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Ragnar {Groot Koerkamp} @curiouscoding.nl · 09/07/2026
My secret 4th ALGO paper is out! We show a tight space lower on non-minimal k-perfect hash functions, generalize PtrHash into a non-minimal k-PHF, and then use it to develop a hash set implementation that is up to 1.6x faster than other hash sets! With Stefan {Hermann, Walzer} and Peter Sanders
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SMT @pp0196.bsky.social · 08/07/2026
ggmlR from Yuri Baramykov is a great #RStats package, i re-use the big work of the selective ggml build infra for the related Rfmalloc Project ggmlR: github.com/Zabis13/ggmlR Rfmalloc monorepo : github.com/sounkou-bioi...
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SMT @pp0196.bsky.social · 06/07/2026
This is for the real lovers of esoterica RSTT: Work-in-progress set-theoretic type algebra for the R language by Mickaël Laurent #RStats, #OCaml, #C API, Programming language theory and set theory repo : github.com/E-Sh4rk/rstt/ with a REPL !
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Mickaël CANOUIL, Ph.D. @mickael.canouil.fr · 01/07/2026
My day job is to conduct statistical analysis of omics data, and most of it is spent writing R. In this new blog post, I share the R package shape I reached for in my recent projects. mickael.canouil.fr/posts/2026-0... #RStats #Shiny #Quarto #OpenSource #DataScience
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SMT @pp0196.bsky.social · 01/07/2026
since i am doing lot of pi based vibesloping these days and R markdown is my testing framework, made piknit #RStats package with Slope Code for a coming work github.com/sounkou-bioi...
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SMT @pp0196.bsky.social · 29/06/2026
cited Marx one time in a session, and now Slope Code autocompletes "idealist" at each new concepts "discovery". Below i suggest let's see what are the lazy eval/effect type of libraries in the Typescript (for my own culture) world just like in #RStats : --->Idealist
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Tyler Morgan-Wall @tylermw.com · 29/06/2026
‼️Big package update on CRAN! #raymolecule v0.9.0 brings ribbon diagrams! Grab PDB files directly from the RCSB Protein Data Bank with just their PDB ID and render it in #RStats with #rayrender or #rayvertex: it's that easy! read_pdb("2w5o") |> generate_ribbon_scene() |> render_model()
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troy_phd @troyhernandez.bsky.social · 26/06/2026
Now you can use your Claude or ChatGPT subscription to run the R agent harness, corteza. No API key, no per-token meter, and it's on CRAN! Thanks to @hadley.nz for the provider-native search idea, and to @pp0196.bsky.social, whose Codex OAuth PR became tinyoauth. cornball.ai/posts/claude...
cornball.ai
Claude and Codex subscriptions, now driving an R agent
A couple of months ago, corteza was an R session you could hand to an LLM, as long as you fed it an API key and watched the per-token meter tick. As of this week you can point it at your Claude Pro/Ma...
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Charlie Gao @shikokuchuo.net · 12/06/2026
New release of secretbase 1.3.0 - a cryptography and data encoding toolkit. Adds base64 URL-safe variants. This is in addition to sha256, sha3, shake256, keccak, siphash, base58, cbor, json etc. all in 40kB. This package provides secure hashing for {targets}. #Rstats github.com/shikokuchuo/...
github.com
GitHub - shikokuchuo/secretbase: secretbase - Cryptographic Hash Functions and Data Encoding
secretbase - Cryptographic Hash Functions and Data Encoding - shikokuchuo/secretbase
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Gabor Csardi @gaborcsardi.org · 11/06/2026
#Rstats package update: zip 3.0.0 with some very cool new things: password protected zip files, vectorized and concurrent unzip(), unzip over HTTP, progress bars. Full change log at github.com/r-lib/zip/re...
github.com
Releases · r-lib/zip
Platform independent zip compression via miniz. Contribute to r-lib/zip development by creating an account on GitHub.
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troy_phd @troyhernandez.bsky.social · 11/06/2026
I’m excited to announce that #codex is now available (typically through a chatGPT subscription) from R through corteza. Logging in is enabled by the dev version of the new tinyoauth package, already in the CRAN queue! A big thank you to @pp0196.bsky.social for the contribution.
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SMT @pp0196.bsky.social · 10/06/2026
Beware #Rstats users, according to Misanthropic, an R to C transpiler is a security risk 😄 Fable turned out to as expected to be La Fable I think some french speaker at Misanthropic is doing some kind of joke with these model names
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SMT @pp0196.bsky.social · 07/06/2026
Rbebelm: #RStats Bindings for 'BebeLM' 'CPU' Inference For A 8B-1B Active model, not that bad A tiny R CLI "Agent" inspired by Corteza github.com/cornball-ai/... repo: github.com/sounkou-bioi... Upstream Rust crate : github.com/maximecb/beb... LFM2.5-8B-A1B blog: www.liquid.ai/blog/lfm2-5-...
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SMT @pp0196.bsky.social · 03/06/2026
Ropendal: Abstract Filesystem access in #Rstats via 'Apache OpenDAL' R/Rust package using #savvy and exporting a C API because i for whatever reason i frequently download terabytes from Google Drive. Async API is heavily by #nanonext. Several time faster than paws for most ops at MinIO baseline
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SMT @pp0196.bsky.social · 28/05/2026
RsimdDispatch: Runtime 'SIMD' Dispatch Templates for 'C' Code in #RStats Packages hellorust.multiversion: Minimal Rust SIMD Multiversioning Example for #RStats A way to enjoy both Linux binary Packages and Optimized code at runtime. github.com/sounkou-bioi... github.com/sounkou-bioi...
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BF Francis Ouellette @bffo.bsky.social · 23/05/2026
academic.oup.com/bioinformati...
academic.oup.com
BLIT: an R package for seamless integration of command-line bioinformatics tool universe
AbstractMotivation. Modern computational biology relies heavily on command-line tools that underpin analytical workflows, yet integrating these tools into
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Daniel Kaschta @danielkaschta.bsky.social · 22/05/2026
Our medRxiv preprint is out: Automated versus manual reanalysis in rare disease genomics. We reanalysed 377 rare disease cases from a routine diagnostic genome sequencing cohort, comparing the established manual workflow with Talos-based automation. www.medrxiv.org/content/10.6...
medrxiv.org
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Open Targets @opentargets.org · 21/05/2026
We conducted the most extensive systematic GWAS gene prioritisation to date across all openly available data, with a retrospective analysis of 100,526 GWAS over the past decade: www.biorxiv.org/content/10.6...
biorxiv.org
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SMT @pp0196.bsky.social · 20/05/2026
Rducks: Register arbitrary #Rstats User-Defined Functions in duckdb-r (1.5.2) including (sacrilege) distributed chunk execution mode via #mirai+libnng. Arrow C Data marshaling dance that that may be removed later. Trivial #duckplyr integration. Stream DuckDB queries repo: github.com/sounkou-bioi...
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SMT @pp0196.bsky.social · 19/05/2026
#duckplyr with no fallbacks, because why not Learned that prefixing a function call with `dd$` is a way to call arbitrary duckdb functions (in our case a registered #RStats UDF) duckplyr.tidyverse.org/dev/articles...
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SMT @pp0196.bsky.social · 19/05/2026
@hannes.muehleisen.org are their plans to expose the (de) serialization primitives used in quack in the next C (unstable) stable API? Wld allow some (ridiculous) applications like the multiprocess/distributed #RStats scalar UDF execution mode via arrow IPC i am using here github.com/sounkou-bioi...
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The R Foundation @r-foundation.bsky.social · 13/04/2026
It is with great sadness that we announce the passing on 1 April of Tomáš Kalibera, a valuable member of the R Core Team for close to 10 years, after a short but aggressive illness. Tomáš is survived by his wife and 1 year old son. A full obituary will be posted in due time.
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SMT @pp0196.bsky.social · 18/05/2026
Use Claude code to fix some ci yaml crap or other minor issue and all of the sudden the LLM is a "contributor" on your repo, anthroslopic and the weird misanthropic co-author default
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SMT @pp0196.bsky.social · 17/05/2026
Some performance tuning (row batching size, schema sharing, streaming) get the ducknng arrow IPC to 30% slower than quack_query at 10 Million rows, our own adaptation of the DuckDB internal application/vnd.duckdb serializer is 20% faster than quack_query ! Even faster over tcp #nng #DuckDB #quack
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SMT @pp0196.bsky.social · 17/05/2026
Reproduction of the drogonR benchmark after addition of additional #RStats http frameworks No-op setup (adding some actual work should be fairer to plumber2-mirai) drogonR 10x>> nanonext 2x> RestRServe 10x>> httpuv/plumber(2) Vibecoded repo for issues with the setup github.com/sounkou-bioi...
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SMT @pp0196.bsky.social · 17/05/2026
drogonR: High-performance HTTP server for #RStats, powered by the Drogon C++ framework by Yuri Baramykov Order of magnitude faster than httpuv/plumber with SSE support out of the box github.com/Zabis13/drog... #Network
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SMT @pp0196.bsky.social · 17/05/2026
ggmlR: #Rstats bindinds to 'GGML' Tensor Operations for Machine Learning by Yuri Baramykov github.com/Zabis13/ggmlR #DeepLearning
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SMT @pp0196.bsky.social · 13/05/2026
Release of version 0.1.1 of the duckdb community extension ducknng: a nanonext inspired DuckDB C extension providing binding to the NNG scalability protocols and a Arrow IPC RPC based Framework Call into any NNG (or http) speaking runtime. What better example than calling a nanonext #RStats server
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John Coene @john-coene.com · 12/05/2026
Watch me ramble about #rstats in an attempt to introduce my "builder" preprocessor. Word count: - "heh" - 56 - "ah" - 47 - "hmmm" - 34 - "..." - 23 - *inaudible - 17 youtu.be/VBj6Q8Ad6aU?...
youtu.be
Builder - a preprocessor for R
YouTube video by John Coene
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Charlie Gao @shikokuchuo.net · 12/05/2026
Async R gets a proper memory model. mirai 2.7.0 and mori 0.2.0 on CRAN: - byte-level dispatcher queue cap: `daemons(memory = ...)` - non-blocking submit on a full queue: `try_mirai()` - mori out of experimental – zero-copy shared memory across processes opensource.posit.co/blog/2026-05... #rstats
opensource.posit.co
A memory model for production async R: mirai 2.7.0 and mori 0.2.0
Two CRAN releases extend R's foundations for production async: bounded queues and `try_mirai()` in mirai 2.7.0, plus mori 0.2.0 graduating from experimental status.
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